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e.ploring the.e.fe.ts of a.thropoge.ic disturba.ce.on pre.a.or inspe.tion a.tivity in Trinida.ia. guppie.

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Curre.t Zoology 2024年第1期70卷 109-111页

作者： a.ix J.P Brusse.u laurence e.a.feyten a.a. L.Cra.e.Gra.t e.Brown De.a.tme.t of Biology Concordia UniversityMontrealQCH4B 1R6Canada De.a.tme.t of Biome.ica. Scie.ce. WCVMUniversity of SaskatchewanSaskatoonSKCanada

Pre. a.ima.s a.e.ofte. fa.e. with unce.ta.nty due.to ha.ing impe.fe.t informa.ion re.a.ding curre.t loca. conditions,including pre.a.ion risks a.d the.a.a.la.ility of re.ia.le.fora.ing opportunitie.(Da.l 2010).a. this unce.ta.nty incre.se.,the.proba.ility of ma.ing costly be.a.iora. e.rors a.so incre.se.,le.ding to more.risk a.e.se.be.a.iora. ta.tics(feyten e. a..2019).For e.a.ple.Trinida.ia. guppie. Poe.ilia.re.icula.a.a.e.fa. more.risk a.e.se.whe. fa.e. with multiple.unknown source. of risk a.se.sme.t informa.ion tha. whe. fa.e. with a.mix of known a.d unknown cue.(feyten e. a..2019).Pre. ca. re.uce.unce.ta.nty by ga.he.ing a.d inte.ra.ing priva.e.a.d socia. informa.ion re.a.ding curre.t risk le.e.s within microha.ita.s(Da.l 2010;Munoz a.d Blumste.n 2012).

关键词： huma. disturba.ce informa.ion a.a.la.ility informa.ion re.ia.ility pre.a.or-pre. inte.a.tions risk a.se.sme.t unce.ta.nty

Disturba.ce.cue.communica.ion is sha.e. by e.itte. die. a.d re.e.ve. ba.kground risk in Trinida.ia. guppie.

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Curre.t Zoology 2022年第4期68卷 433-440页

作者： Ja.k a.Goldma. a.a. L Cra.e.laurence e.a.feyten e.ily Collins Gra.t e.Brown De.a.tme.t of Biology Concordia University7141 Sherbrooke Street WestMontrealQCCanada H4B 1R6

In a.ima. communica.ion syste.s,individua.s tha. de.e.t a.cue.i.e.,“re.e.ve.s”)a.e.ofte. influe.ce. by cha.a.te.istics of the.cue.*** insta.ce.in ma.y spe.ie.,re.e.ve.s a.oid che.ica. cue. tha. a.e.re.e.se. by e.itte.s e.pe.ie.cing *** che.ica.“disturba.ce.cue.”a.pe.r to be.e.it re.e.ve.s by wa.ning the. a.out ne.rby da.ge.,such a. a.pre.a.or’s *** the.a.tive.ingre.ie.ts in disturba.ce.cue. ha.e.be.n la.ge.y une.plore.,by-products of me.a.olize. prote.n a.e.thought to pla. a.role.for some.*** so,the.conte.t(qua.ity)a.d volume.qua.tity)of the.e.itte.’s die. should a.fe.t the.r disturba.ce.cue.,thus a.te.ing how re.e.ve.s pe.ce.ve.the.cue. a.d *** Poe.ilia.re.icula.a.a.e.a.spe.ie. known to discrimina.e.a.ong disturba.ce.cue. from diffe.e.t type. of donors,but die.a.y va.ia.ion ha. ye. to be.*** this study,we.found e.ide.ce.tha. die. qua.ity a.d qua.tity ca. a.fe.t disturba.ce.cue. re.e.se. by guppy e.itte.s(i.e.,e.pe.ime.ta.“donors”).Re.e.ve.s discrimina.e. be.we.n donor cue.tre.tme.ts,re.ponding more.strongly to cue. from donors fe. a.prote.n-rich bloodworm die.(e.pe.ime.t 1),a. we.l a. a. ove.a.l la.ge. die.(e.pe.ime.t 2).We.a.so found tha. re.e.ve.s e.pose. to highe. ba.kground risk we.e.more.se.sitive.to disturba.ce.cue.va.ia.ion,with the.stronge.t a.oida.ce.re.ponse. displa.e. by high-risk re.e.ve.s towa.d disturba.ce.cue. from donors fe. the.high-qua.ity ***,die.,a.d pe.ha.s prote.n spe.ifica.ly,a.fe.ts e.the. the.conce.tra.ion or composition of disturba.ce.cue. re.e.se. by *** va.ia.ion ma. be.importa.t in informa.ion signa.ing in socia. spe.ie. like.the.guppy.

关键词： a.a.m cue. che.ica. cue. die. qua.ity die. qua.tity prote.n

Re.ilie.ce. the.6th Vita. Sign: Conce.tua.izing, Conte.tua.izing, a.d Ope.a.iona.izing a.l Six Vita. Signs

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He.lth 2024年第7期16卷 657-673页

作者： Rose.e. Consta.tino Be.ty J. Bra.te. Chi Ching Vivia. Hui La.issa.C. a.le. Lillia. J. Wolfe.Ka.he.ine.H. e.dre. Je.yl Ce.pron Cuta.ora.laurence L. Ga.cia.Da.sy R. Pa.ompon Ka.hle.n Thimse. Bra.de. N. Ka.e. Ma.ga.e.e.L. Za.on De.a.tme.t of He.lth a.d Community Syste.s School of Nursing University of Pittsburgh Pittsburgh PA USA Unde.gra.ua.e.a.fa.rs School of Nursing University of Pittsburgh Pittsburgh PA USA The.Hong Kong Polyte.hnic Unive.sity Hong Kong China School of Nursing Adjunct Faculty at the University of Pittsburgh Pittsburgh PA USA School of Nursing University of Pittsburgh Pittsburgh PA USA De.a.tme.t of He.lth Promotion a.d De.e.opme.t School of Nursing University of Pittsburgh Pittsburgh PA USA Colle.e.of Nursing Cebu Normal University Cebu City Philippines School of Nursing University of Nevada Las Vegas USA De.a.tme.t of He.lth a.d Community Syste.s University of Pittsburgh PA USA De.a.tme.t of Nursing University of Scranton Scranton PA USA

The.e.a.e.five.vita. signs tha. he.lthca.e.provide.s a.se.s: te.pe.a.ure. pulse. re.pira.ion, blood pre.sure. a.d pa.n. Norma. le.e.s for the.five.vita. signs a.e.publishe. by the.a.e.ica. He.rt a.socia.ion, a.d othe. spe.ia.ty orga.iza.ions, howe.e., the.sixth vita. sign (re.ilie.ce. which a.opts the.me.sure.of immune.re.ilie.ce.is sugge.te. in this pa.e.. Re.ilie.ce.is the.a.ility of the.immune.syste. to re.pond to a.ta.ks a.d de.e.d e.fe.tive.y a.a.nst infe.tions a.d infla.ma.ory stre.sors, a.d psychologica. re.ilie.ce.is the.ca.a.ity to re.ist, a.a.t, re.ove., thrive. a.d grow from a.cha.le.ge.or a.stre.sor. Individua.s with be.te. optima. immune.re.ilie.ce.ha. be.te. he.lth outcome. tha. those.with minima. immune.re.ilie.ce. The.purpose.of this pa.e. is to conce.tua.ize. conte.tua.ize. a.d ope.a.iona.ize.a.l six vita. signs. We.sugge.t me.suring re.ilie.ce.subje.tive.y a.d obje.tive.y. Subje.tive.y, use.a.5-ite. guide. inte.vie. re.ise. from the.Connor-Da.idson Re.ilie.ce.Sca.e.(CDRC), a.sca.e.of 10 ite.s. The.re.ise. CDRC sca.e.is a.5-ite. sca.e. The.sca.e.is ra.e. on a.5-point Like.t sca.e.from 0 (not true. to 4 (true.a.l the.time.. The.tota. score.ra.ge. from 0 to 20, with highe. tota. score. indica.ing gre.te. re.ilie.ce. The.sca.e.de.onstra.e. good construct va.idity a.d inte.na. consiste.cy (α = 0.85) during the.de.e.opme.t of the.sca.e. The.CD-RISC ha. a.good Cronba.h’s a.pha.le.e. of 0.85. The.Re.ise. CD-RISC ca. be.comple.e. in 2 - 4 minute.. To me.sure.re.ilie.ce.obje.tive.y, we.sugge.t using Immune.Re.ilie.ce.(IR) le.e.s, the.le.e. of re.ilie.ce.to pre.e.ve.a.d/or ra.idly re.tore.immune.re.ilie.ce.functions tha. promote.dise.se.re.ista.ce.a.d control infla.ma.ion a.d othe. infla.ma.ory stre.s. IR le.e.s a.e.ga.ge. with two pe.iphe.a. blood me.rics tha. qua.tify the.ba.a.ce.be.we.n CD8 a.d CD4 T-ce.l le.e.s a.d ge.e.e.pre.sion signa.ure. tra.king longe.ity-a.socia.e. immunocompe.e.ce.a.d morta.ity- or e.tropy-a.socia.e. infla.ma.ion. IR de.e.ula.ion i

关键词： Conce.tua.iza.ion Conte.tua.iza.ion Ope.a.iona.iza.ion Body Te.pe.a.ure Pulse Re.pira.ion Blood Pre.sure Pa.n Re.ilie.ce

Se.de. a.d re.e.ve. e.pe.ie.ce.a.te.s the.re.ponse.of fish to disturba.ce.cue.

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Curre.t Zoology 2020年第3期66卷 255-261页

作者： Ja.k a.GOLDMa. laurence e.a.feyten Inda. W.Ra.Na.INe.Gra.t e.BROWN De.a.tme.t of Biology Concordia University7141 Sherbrooke St.WestMontrealQCH4B 1R6Canada De.a.tme.t of Lifte.Scie.ce. University of the West IndiesSt.AugustineTrinidad and Tobago

Pre.a.ion is a.pe.va.ive.se.e.tion pre.sure.sha.ing morphologica.,physiologica.,a.d be.a.iora. phe.otype. of pre. *** studie. ha.e.be.un to e.a.ine.how the.e.fe.ts of individua. e.pe.ie.ce.with pre.a.ion risk sha.e. the.use.of publicly a.a.la.le.risk a.se.sme.t ***,we.inve.tiga.e. the.e.fe.ts of prior pre.a.ion risk e.pe.ie.ce.on disturba.ce.cue.production a.d use.by Trinida.ia. guppie. Poe.ilia.re.icula.a.unde. la.ora.ory *** our first e.pe.ime.t,we.de.onstra.e.tha. the.re.ponse.of guppie. from a.high pre.a.ion popula.ion(Lopinot Rive.)wa. de.e.de.t upon the.source.of disturba.ce.cue.se.de.s(high *** pre.a.ion popula.ions).Howe.e.,guppie. colle.te. from a.low pre.a.ion site.Uppe. a.ipo Rive.)e.hibite. simila. re.ponse. to disturba.ce.cue.,re.a.dle.s of the.se.de. *** our se.ond e.pe.ime.t,we.use. la.ora.ory stra.n guppie. e.pose. to high ve.sus low ba.kground risk *** re.ults show a. a.a.ogous re.ponse.pa.te.ns a. shown for our first *** e.pose. to high ba.kground risk conditions e.hibite. stronge. re.ponse. to the.disturba.ce.cue. colle.te. from se.de.s e.pose. to high(***)risk conditions a.d guppie. e.pose. to low risk conditions we.e.not influe.ce. by se.de. ***,our re.ults sugge.t tha. e.pe.ie.ce.with ba.kground pre.a.ion risk significa.tly impa.ts both the.production of a.d re.ponse.to disturba.ce.cue. in guppie..

关键词： disturba.ce.cue. e.ology of informa.ion pe.ce.ve. risk pre.a.or-pre. inte.a.tions Trinida.ia. guppy

Urba. he.t mitiga.ion by gre.n a.d blue.infra.tructure.Drive.s,e.fe.tive.e.s,a.d future.ne.ds

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The.Innova.ion 2024年第2期5卷 145-166页

作者： Pra.ha.t Kuma. Sisa. e.De.e.e.Sohe.la.Kha.ili Christos H.Ha.ios Je.te.dra.Sa.a.i Na.rin a.ha.oha.ma.i Ma.ia.de.Fa.ima.a.dra.e.Ma.ia.a.ha.a.sia.ou Ka.a.de.p Bhui Ne.e. Ca.villo Shi-Jie.Ca. Fre.e.ic Coulon Jill L.e.mondson Da.id Fle.che. e.milson Dia. de.Fre.ta. Ha. Guo Ma.the. C.Hort Ma.husuda. Ka.ti Thoma. Rodding Kje.dse. Ste.fe. Le.ma.n Giulia.o Ma.e.li Locosse.li She.a.h K.Ma.ha. Lidia.Mora.ska.Ra.a. Pa.a.uli Christophe. D.F.Roge.s Runming Ya. Fa.g Wa.g Ja.nis We.k laurence Jone. Globa. Ce.tre.for Cle.n a.r Re.e.rch(GCa.e. School of SustainabilityCivil and Environmental EngineeringFaculty of Engineering and Physical SciencesUniversity of SurreyGuildford GU27XHUK Institute.for Susta.na.ility University of SurreyGuildford GU27XHSurreyUK School of Built e.vironme.t University of ReadingWhiteknightsReading RG66BUUK School De.ign a.d the.Built e.vironme.t Curtin University Sustainability Policy InstituteKent StBentley 6102Western Australia Ha.ry Butle. Institute Murdoch UniversityMurdoch 6150Western Australia a.mosphe.ic Scie.ce. De.a.tme.t Institute of AstronomyGeophysics and Atmospheric SciencesUniversity of Sao PauloSao Paulo 05508-090Brazil Me. Office FitzRoy RoadExeter EX13PBUK De.a.tme.t of Psychia.ry a.d Nuffie.d De.a.tme.t of Prima.y Ca.e.He.lth Scie.ce. Wadham CollegeUniversity of OxfordOxfordUK Ce.tre.for Inte.disciplina.y Me.hodologie. University of WarwickWarwickUK School of a.chite.ture Southeast University2 SipailouNanjing 210096China Cra.fie.d Unive.sity School of WaterEnvironment and EnergyCranfield MK430ALUK Pla.ts PhotosynthesisSoil ClusterSchool of BiosciencesUniversity of SheffieldSheffield S102TNUK UK Ce.tre.for e.ology&Hydrology Environment Centre WalesDeiniol RoadBangor LL572UWUK a.r Qua.ity Studie. Department of Civil and Environmental EngineeringThe Hong Kong Polytechnic UniversityHong KongChina De.a.tme.t of Fore.try a.d e.vironme.ta. Re.ource. Faculty Excellence Program for Leadership in Public ScienceNorth Carolina State UniversityChancellorRaleighNC 27695USA De.a.tme.ts of a.chite.ture.Civil e.gine.ring and Chemical EngineeringUniversity of BathBath BA27AYUK School of a.chite.ture University of NevadaLas VegasNV 89154USA De.a.tme.t of Tropica. e.osyste.s Functioning Center of Nuclear Energy in AgricultureUniversity of São PauloPiracicaba 13416-000Sao PauloBrazil School of Oce.n Scie.ce. Bangor UniversityMenai BridgeAnglesey LL595 ABUK Inte.na.iona. La.ora.ory for a.r Qua.ity a.d He.lth Science and Engine

The.combina.ion of urba.iza.ion a.d globa. wa.ming le.ds to urba. ove.he.ting a.d compounds the.fre.ue.cy a.d inte.sity of e.tre.e.he.t e.e.ts due.to clima.e.***,the.risk of urba. ove.he.ting ca. be.mitiga.e. by urba. gre.n-blue.gre. infra.tructure.GBGI),such a. pa.ks,we.la.ds,a.d e.gine.re. gre.ning,which ha.e.the.pote.tia. to e.fe.tive.y re.uce.summe. a.r *** ma.y re.ie.s,the.e.ide.ce.ba.e. on qua.tifie. GBGI cooling be.e.its re.a.ns pa.tia. a.d the.pra.tica. re.omme.da.ions for imple.e.ta.ion a.e.*** syste.a.ic lite.a.ure.re.ie. synthe.ize. the.e.ide.ce.ba.e.for he.t mitiga.ion a.d re.a.e. co-be.e.its,ide.tifie. knowle.ge.ga.s,a.d propose. re.omme.da.ions for the.r imple.e.ta.ion to ma.imize.the.r *** scre.ning 27,486 pa.e.s,202 we.e.re.ie.e.,ba.e. on 51 GBGI type. ca.e.orize. unde. 10 ma.n *** GBGI(gre.n wa.ls,pa.ks,stre.t tre.s)ha.e.be.n we.l re.e.rche. for the.r urba. cooling ***,se.e.a. othe. GBGI ha.e.re.e.ve. ne.ligible.zoologica. ga.de.,golf course.e.tua.y)or minima.(priva.e.ga.de.,a.lotme.t)*** most e.ficie.t a.r cooling wa. obse.ve. in bota.ica. ga.de.s(5.0±3.5℃),we.la.ds(4.9±3.2℃),gre.n wa.ls(4.1±4.2℃),stre.t tre.s(3.8±3.1℃),a.d ve.e.a.e. ba.conie.(3.8±2.7℃).Unde. cha.ging clima.e.conditions(2070–2100)with conside.a.ion of RCP8.5,the.e.is a.shift in clima.e.subtype.,e.the. within the.sa.e.clima.e.zone.e.g.,Dfa.to Dfb a.d Cfb to Cfa.or a.ross othe. clima.e.zone.(e.g.,Dfb[contine.ta. wa.m-summe. humid]to BSk[dry,cold se.i-a.id]a.d Cwa.te.pe.a.e.to a.[tropica.]).The.e.shifts ma. re.ult in lowe. e.ficie.cy for the.curre.t GBGI in the.*** the.importa.ce.of multiple.se.vice.,it is crucia. to ba.a.ce.the.r functiona.ity,cooling pe.forma.ce.a.d othe. re.a.e. co-be.e.its whe. pla.ning for the.future.*** globa. GBGI he.t mitiga.ion inve.tory ca. a.sist policyma.e.s a.d urba. pla.ne.s in prioritizing e.fe.tive.inte.ve.tions to re.uce.the.risk of urba. ove.he.ting,fi

关键词： e.tua.y wa.ls e.tre.e

The.e.fe.t of ozone.on pine.fore.ts in South-e.ste.n Fra.ce.from 2017 to 2019

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Journa. of Fore.try Re.e.rch 2023年第2期34卷 301-315页

作者： a.umol Sha.hikuma. Sve.la.a.Bičárová Da.ste.n-Richie. laurence Groupe.Inte.na.iona. d′e.ude. De. Forêts Sud-e.ropée.ne.(G.I.e.F.S) 69Avenue des Hespérides06300 NiceFrance Institute.of e.rth Scie.ce.of the.Slova. a.a.e.y of Scie.ce. 05960 StaráLesnáTatranskáLomnicaSlovakia

In South-e.ste.n fore.ts of Fra.ce.risks linke. to the.e.fe.ts of troposphe.ic ozone.O_(3))a.e.re.l;its a.nua. impa.t ha. be.n obse.ve. spe.ifica.ly ne.r the.coa.tline.a.d in high a.titude.mounta.ns during the.pe.iod *** this study,the.risk a.se.sme.t of O_(3)polluta.t wa. ca.rie. out using two a.proa.he. ba.e. on fore.t re.ponse.indica.ors such a. O_(3)spe.ific folia. visible.injury a.d by stoma.a. O_(3)*** O_(3)dose.va.ue.(POD_(0))we.e.obta.ne. by the.DO_(3)Se.*** mode. re.uire. hourly O_(3)conce.tra.ion for POD_(0)ca.cula.ion.a.modifie. a.proa.h tha. use. me.sure.e.ts from pa.sive.sa.ple.s(monthly a.e.a.e.O_(3)conce.tra.ion)wa. te.te. for the.ca.cula.ion of POD_(0)a.d te.t re.ults showe. good a.re.me.t with the.POD_(0)ca.cula.e. using hourly O_(3)*** the.mode. input file.the.a.e.a.e.O_(3)conce.tra.ion is use. for POD_(0),a.d this could be.use.ul for POD_(0)ca.cula.ion whe. the.a.tive.monitor is *** this study,a.flux-ba.e. a.se.sme.t provide. be.te. corre.a.ion with O_(3)spe.ific le.f injury,which is a.so *** visible.injury in re.ponse.to O_(3)indica.e. tha. Pinus ce.bra.a.d Pinus ha.e.e.sis a.e.more.a.fe.te. a.d the.e.ore.more.se.sitive.tha. Pinus *** POD_(0)a.d stoma.a. conducta.ce.Gsto)se.m to be.induce. by e.vironme.ta. fa.tors,prima.ily ra.nfa.l a.d the.soil wa.e. pote.tia.(fSWP).The.corre.a.ion be.we.n the.O_(3)flux me.ric a.d e.vironme.ta. va.ia.le. with fore.t re.ponse.indica.ors by Spe.rma. ra.k te.t confirms *** a. one.of the.most se.sitive.spe.ie. to O_(3).

关键词： Ozone Folia. visible.injury Phytotoxic ozone.dose Stoma.a. conducta.ce DO_(3)Se

Non-surgica. the.a.y of Pe.ronie.s dise.se

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a.ia. Journa. of a.drology 2008年第1期10卷 79-87页

作者： Fre.e.ick L. Ta.lor laurence a. Le.ine De.a.tme.t of Urology Rush University Medical Center Chicago 60612 USA

The.pre.e.t pa.e. provide. a.re.ie. of the.a.a.la.le.non-surgica. tre.tme.ts for Pe.ronie.s dise.se.（PD）. a.re.ie. of publishe. lite.a.ure.on ora., intra.e.iona., e.te.na. e.e.gy a.d iontophore.is the.a.ie. for PD wa. pe.forme., a.d the.publishe. re.ults of a.a.la.le.tre.tme.t options re.ie.e.. The.a.thors＇ re.omme.da.ions for a.propria.e.non-surgica. ma.a.e.e.t of PD a.e.provide.. a.though the.e.a.e.ma.y publishe. re.orts tha. show the.e.fica.y of non-surgica. the.a.ie. for PD, the.e.is a.la.k of la.ge.sca.e. multice.te. controlle. clinica. tria.s, which ma.e. tre.tme.t re.omme.da.ions difficult. Ca.e.ul re.ie. of the.lite.a.ure.doe. sugge.t tha. the.e.a.e.tre.tme.t options tha. ma.e.scie.tific se.se.a.d a.pe.r to sta.ilize.the.dise.se.proce.s, re.uce.de.ormity, a.d improve.function. Offe.ing no tre.tme.t a. a.l will e.coura.e.our pa.ie.ts to pursue.a.te.na.ive.tre.tme.ts, which might do ha.m, a.d misse. the.opportunity to do some.good. Cle.rly furthe. work is ne.e.sa.y to de.e.op sa.e.a.d e.fe.tive.non-surgica. tre.tme.ts for PD.

关键词： Pe.ronie.s dise.se pe.ile.indura.ion huma.s inje.tions intra.e.iona. vita.in e pe.toxifylline a.ino a.ids

Policy options for a.riculture.Gre.n De.e.opme.t by fa.me.s in China

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Frontie.s of a.ricultura. Scie.ce.a.d e.gine.ring 2020年第1期7卷 90-97页

作者： laurence e.D.SMITH Ce.tre.for De.e.opme.t Environment and PolicySOAS University of LondonLondonWC1H OXGUK

Fa.me.s a.e.the.ke. a.e.ts who ma.a.e.la.d a.d *** Gre.n De.e.opme.t(a.D)re.uire. a.tra.sforma.ion in fa.ming from high re.ource.consumption a.d e.vironme.ta. cost to susta.na.le.inte.sifica.ion with high productivity,high re.ource.use.e.ficie.cy a.d low e.vironme.ta. *** pa.e. a.a.yze. the.public policy cha.le.ge.of a.D a.d ma.e. the.ca.e.for a.loca.ion-se.sitive.policy mix ma.e.up of re.ula.ion,a.vice.provision,volunta.ism a.d ta.ge.e. *** public a.ricultura. e.te.sion se.vice.in China.is a.ke. re.ource.but one.tha. re.uire. re.rie.ta.ion a.d re.orm with the.a.m of be.te. ba.a.cing high fa.m productivity with e.vironme.ta. prote.tion.

关键词： a.riculture e.vironme.t de.e.opme.t ince.tive. policy re.ula.ion

DNa.re.a.r ca.a.ity corre.a.e. with sta.da.dize. upta.e.va.ue. from 18F-fluorode.xyglucose.positron e.ission tomogra.hy/CT in pa.ie.ts with a.va.ce. non-sma.l-ce.l lung ca.ce.

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Chronic Dise.se. a.d Tra.sla.iona. Me.icine 2018年第2期4卷 109-116页

作者： Xin (e.ic) Jia.g Ting Xu Qingyi We. Pe.g Li Da.ie. R. Gome. laurence e. Court Zhongxing Lia. De.a.tme.t of Ra.ia.ion Oncology The University of Texas MD Anderson Cancer CenterHoustonTX 77030USA Duke.Unive.sity DurhamNC 27708USA Duke.Ca.ce. Institute Duke University Medical CenterDurhamNC 27710USA De.a.tme.t of Me.ica. Oncology Henan Cancer HospitalZhengzhouHenan 450008China De.a.tme.t of Ra.ia.ion Physics The University of Texas MD Anderson Cancer CenterHoustonTX 77030USA

Obje.tive. The.DNa.re.a.r ca.a.ity (DRC) of tumor ce.ls is a. importa.t contributor to re.ista.ce.to ra.ia.ion a.d pla.inum-ba.e. drugs. Be.a.se.DRC ma. be.a.fe.te. by tumor ce.l me.a.olism, we.me.sure. DRC in lymphocyte. from pa.ie.ts with non-sma.l-ce.l lung ca.ce. (NSCLC) a.d compa.e. the.findings with the.ma.imum sta.da.dize. upta.e.va.ue.(SUVma.) on 18 F-fluorode.xyglucose.positron e.ission tomogra.hy (FDG Pe.) a.te. (che.o)ra.ia.ion the.a.y. Me.hods: This study include. 151 pa.ie.ts with sta.e.Ia.IV NSCLC who ha. FDG Pe. a. a.single.institution a.d dona.e. blood sa.ple. be.ore.che.othe.a.y. We.a.se.se. the.corre.a.ion of DRC, me.sure. in pe.iphe.a. T lymphocyte. by a.host-ce.l re.c-tiva.ion a.sa. with SUVma. a.d the.r a.socia.ions with ove.a.l surviva. (OS) time.by ha.a.ds ra.ios ca.cula.e. with a.Cox pro-portiona. ha.a.ds re.re.sion mode.. Re.ults: SUVma. of the.prima.y tumor a. dia.nosis wa. inve.se.y a.socia.e. with lymphocyte.DRC (r＝－0.175, P＝0.032), pa.ticula.ly a.ong pa.ie.ts with a.va.ce. dise.se.(r ＝－0.218, P ＝ 0.015). Howe.e., △SUVma. of prima.y tumor wa. not significa.tly a.socia.e. with DRC (r＝0.005, P＝0.968). SUVma. of re.iona. lymph node. a. dia.nosis (r＝－0.307, P＝0.0008) a.d a.te. (che.o)ra.ia.ion tre.tme.t (r＝－0.329, P＝0.034) a.d SUVma. of the.prima.y tumor a.te. (che.o)ra.ia.ion tre.tme.t (r＝－0.253, P＝0.045) we.e.a.so inve.se.y a.socia.e. with OS time. Conclusion: DRC wa. inve.se.y a.socia.e. with prima.y tumor SUVma. be.ore.tre.tme.t but not with △SUVma. a.te. (che.o)ra.ia.ion.

关键词： DNA re.a.r ca.a.ity Sta.da.dize. upta.e va.ue 18F-fluorode.xyglucose positron e.ission tomogra.hy Outcome Non-sma.l-ce.l lung ca.ce.