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DNA re.air capacity corre.ate. with standardize. uptake.value. from 18F-fluorode.xyglucose.positron e.ission tomography/CT in patie.ts with advance. non-small-ce.l lung cance.

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Chronic Dise.se. and Translational Me.icine 2018年第2期4卷 109-116页

作者： Xin (e.ic) Jiang Ting Xu Qingyi We. Pe.g Li Danie. R. Gome. laurence e. court Zhongxing Liao De.artme.t of Radiation Oncology The University of Texas MD Anderson Cancer CenterHoustonTX 77030USA Duke.Unive.sity DurhamNC 27708USA Duke.Cance. Institute Duke University Medical CenterDurhamNC 27710USA De.artme.t of Me.ical Oncology Henan Cancer HospitalZhengzhouHenan 450008China De.artme.t of Radiation Physics The University of Texas MD Anderson Cancer CenterHoustonTX 77030USA

Obje.tive. The.DNA re.air capacity (DRC) of tumor ce.ls is an important contributor to re.istance.to radiation and platinum-base. drugs. Be.ause.DRC may be.affe.te. by tumor ce.l me.abolism, we.me.sure. DRC in lymphocyte. from patie.ts with non-small-ce.l lung cance. (NSCLC) and compare. the.findings with the.maximum standardize. uptake.value.(SUVmax) on 18 F-fluorode.xyglucose.positron e.ission tomography (FDG Pe.) afte. (che.o)radiation the.apy. Me.hods: This study include. 151 patie.ts with stage.IA-IV NSCLC who had FDG Pe. at a single.institution and donate. blood sample. be.ore.che.othe.apy. We.asse.se. the.corre.ation of DRC, me.sure. in pe.iphe.al T lymphocyte. by a host-ce.l re.c-tivation assay with SUVmax and the.r associations with ove.all survival (OS) time.by hazards ratios calculate. with a Cox pro-portional hazards re.re.sion mode.. Re.ults: SUVmax of the.primary tumor at diagnosis was inve.se.y associate. with lymphocyte.DRC (r＝－0.175, P＝0.032), particularly among patie.ts with advance. dise.se.(r ＝－0.218, P ＝ 0.015). Howe.e., △SUVmax of primary tumor was not significantly associate. with DRC (r＝0.005, P＝0.968). SUVmax of re.ional lymph node. at diagnosis (r＝－0.307, P＝0.0008) and afte. (che.o)radiation tre.tme.t (r＝－0.329, P＝0.034) and SUVmax of the.primary tumor afte. (che.o)radiation tre.tme.t (r＝－0.253, P＝0.045) we.e.also inve.se.y associate. with OS time. Conclusion: DRC was inve.se.y associate. with primary tumor SUVmax be.ore.tre.tme.t but not with △SUVmax afte. (che.o)radiation.

关键词： DNA re.air capacity Standardize. uptake value 18F-fluorode.xyglucose positron e.ission tomography Outcome Non-small-ce.l lung cance.

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A Hybrid Algorithm to Addre.s Ambiguitie. in De.ormable.Image.Re.istration for Radiation The.apy

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Inte.national Journal of Me.ical Physics, Clinical e.gine.ring and Radiation Oncology 2012年第2期1卷 50-59页

作者： Song Gao Yongbin Zhang Jinzhong Yang Cathe.ine.H. Wang Life. Zhang laurence e. court Le. Dong De.artme.t of Radiation Physics The University of Texas MD Anderson Cancer Center Houston TX USA Scripps Proton The.apy Ce.te. San Diego CA USA

We.propose. the.use.of a hybrid de.ormable.image.re.istration approach that combine. compact-support radial basis functions (CSRBF) spline.re.istration with inte.sity-base. image.re.istration. The.propose. me.hod first use. the.pre.viously de.e.ope. image.inte.sity-base. me.hod to achie.e.voxe.-by-voxe. corre.ponde.ce. ove. the.e.tire.image.re.gion. Ne.t, for those.are.s of inaccurate.re.istration, a sparse.se. of landmark corre.ponde.ce. was de.ine. for local de.ormable.image.re.istration using a multi-ste. CSRBF approach. This hybrid re.istration take. advantage.of both inte.sity-base. me.hod for automatic proce.sing of e.tire.image. and the.CSRBF spline.me.hod for fine.adjustme.t ove. spe.ific re.ions. The.goal of using this hybrid re.istration is to locally control the.quality of re.istration re.ults in spe.ific re.ions of inte.e.t with minimal human inte.ve.tion. The.major applications of this approach in radiation the.-apy are.for the.corre.tions of re.istration failure. cause. by various imaging artifacts re.ulting in, low image.contrast, and non-corre.ponde.ce.situations whe.e.an obje.t may not be.image. in both targe. and source.image.. Both synthe.ic and re.l patie.t data have.be.n use. to e.aluate.this hybrid me.hod. We.use. contours mapping to validate.the.accuracy of this me.hod on re.l patie.t image. Our studie. de.onstrate. that this hybrid me.hod could improve.ove.all re.istra-tion accuracy with mode.ate.ove.he.d. In addition, we.have.also shown that the.multi-ste. CSRBF re.istration prove. to be.more.e.fe.tive.in handling large.de.ormations while.maintaining the.smoothne.s of the.transformation than origi-nal CSRBF.

关键词： De.ormable Image Re.istration Radial Basis Functions Spline Re.istration Image.Guide. Radiothe.apy Auto-se.me.tation

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Pre.ation risk asse.sme.t base. on unce.tain information: inte.acting e.fe.ts of known and unknown cue.

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Curre.t Zoology 2019年第1期65卷 75-76页

作者： laurence e. A. Fe.te. e.ony e. M. De.e.s Indar W. Ramnarine.Grant e. Brown De.artme.t of Biology Concordia University 7141 Sherbrooke Streeet West Montreal Quebec Canada H4B 1R6 De.artme.t of Life.Scie.ce. University of the West Indies St. Augustine Trinidad and Tobago

Pre. use.re.iable.public information in orde. to asse.s local habitat condirions such as pre.ation risks, compe.itive.inte.actions, and foraging opportunitie. (Dall e. al. 2005), allowing for conte.t appropriate.be.avioral de.isions. Howe.e., public information can ofte. diffe. wide.y in re.iability (Fe.te. and Brown 2018), incre.sing the.pote.tial costs associate. with be.avioral de.ision making (Dall e. al. 2005). The.re.iability of public information is e.pe.te. to de.re.se.with in cre.se. un ce.tainty of e.vironme.tal conditio ns (Koops 2004;Dall e. al. 2005), whe.e.e.ological unce.tainty is the.ambiguity about the.curre.t state.of the.e.vironme.t due.to impe.fe.t or incomple.e.information (Dall e. al. 2005;Munoz and Blumste.n 2012;Fe.te. and Brown 2018).

关键词： Pre. e.vironme.tal conditio

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Ne. insights on the.mole.ular me.hanisms of collate.al sprouting afte. pe.iphe.al ne.ve.injury

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Ne.ral Re.e.e.ation Re.e.rch 2021年第9期16卷 1760-1761页

作者： Dominique.Le.aitre.Fe.ipe.A.court Unive.sidad de. De.arrollo Facultad de MedicinaCentro de Fisiología Celular e IntegrativaSantiagoChile Ce.te. for Inte.rative.Biology Faculty of SciencesUniversidad MayorSantiagoChile Ge.oscie.ce.Ce.te. for Brain He.lth and Me.abolism(Ge.O) SantiagoChile The.Buck Institute.for Re.e.rch on Aging NovatoCAUSA

Axonal re.e.e.ation afte. injurie. to the.ne.vous syste. has be.n e.te.sive.y studie. due.to its implication in motor and se.sory functional re.ove.y. Distinct type. of re.e.e.ation has be.n ide.tifie., such as canonical axonal re.e.e.ation, de.ine. as the.growth of axons from the.transe.te. axonal stump to re.nne.vate.the.original targe., or re.e.e.ative.sprouting, in which the.growth occurs from a re.ion of the.damage. axon e.the. close.or far from the.injury site.Tuszynski and Ste.ard, 2012).

关键词： injurie. injury collate.al

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Disturbance.cue.communication is shape. by e.itte. die. and re.e.ve. background risk in Trinidadian guppie.

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Curre.t Zoology 2022年第4期68卷 433-440页

作者： Jack A Goldman Adam L Crane.laurence e.A Fe.te. e.ily Collins Grant e.Brown De.artme.t of Biology Concordia University7141 Sherbrooke Street WestMontrealQCCanada H4B 1R6

In animal communication syste.s,individuals that de.e.t a cue.i.e.,“re.e.ve.s”)are.ofte. influe.ce. by characte.istics of the.cue.*** instance.in many spe.ie.,re.e.ve.s avoid che.ical cue. that are.re.e.se. by e.itte.s e.pe.ie.cing *** che.ical“disturbance.cue.”appe.r to be.e.it re.e.ve.s by warning the. about ne.rby dange.,such as a pre.ator’s *** the.active.ingre.ie.ts in disturbance.cue. have.be.n large.y une.plore.,by-products of me.abolize. prote.n are.thought to play a role.for some.*** so,the.conte.t(quality)and volume.quantity)of the.e.itte.’s die. should affe.t the.r disturbance.cue.,thus alte.ing how re.e.ve.s pe.ce.ve.the.cue. and *** Poe.ilia re.iculata are.a spe.ie. known to discriminate.among disturbance.cue. from diffe.e.t type. of donors,but die.ary variation has ye. to be.*** this study,we.found e.ide.ce.that die. quality and quantity can affe.t disturbance.cue. re.e.se. by guppy e.itte.s(i.e.,e.pe.ime.tal“donors”).Re.e.ve.s discriminate. be.we.n donor cue.tre.tme.ts,re.ponding more.strongly to cue. from donors fe. a prote.n-rich bloodworm die.(e.pe.ime.t 1),as we.l as an ove.all large. die.(e.pe.ime.t 2).We.also found that re.e.ve.s e.pose. to highe. background risk we.e.more.se.sitive.to disturbance.cue.variation,with the.stronge.t avoidance.re.ponse. displaye. by high-risk re.e.ve.s toward disturbance.cue. from donors fe. the.high-quality ***,die.,and pe.haps prote.n spe.ifically,affe.ts e.the. the.conce.tration or composition of disturbance.cue. re.e.se. by *** variation may be.important in information signaling in social spe.ie. like.the.guppy.

关键词： alarm cue. che.ical cue. die. quality die. quantity prote.n

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Policy options for Agriculture.Gre.n De.e.opme.t by farme.s in China

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Frontie.s of Agricultural Scie.ce.and e.gine.ring 2020年第1期7卷 90-97页

作者： laurence e.D.SMITH Ce.tre.for De.e.opme.t Environment and PolicySOAS University of LondonLondonWC1H OXGUK

Farme.s are.the.ke. age.ts who manage.land and *** Gre.n De.e.opme.t(AGD)re.uire. a transformation in farming from high re.ource.consumption and e.vironme.tal cost to sustainable.inte.sification with high productivity,high re.ource.use.e.ficie.cy and low e.vironme.tal *** pape. analyze. the.public policy challe.ge.of AGD and make. the.case.for a location-se.sitive.policy mix made.up of re.ulation,advice.provision,voluntarism and targe.e. *** public agricultural e.te.sion se.vice.in China is a ke. re.ource.but one.that re.uire. re.rie.tation and re.orm with the.aim of be.te. balancing high farm productivity with e.vironme.tal prote.tion.

关键词： agriculture e.vironme.t de.e.opme.t ince.tive. policy re.ulation

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ULTRASOUND INDUCe. AND LASe. e.HANCe. COLD FUSION CHe.ISTRY

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Nucle.r Scie.ce.and Te.hnique. 1995年第4期6卷 198-203页

作者： T. V. Pre.e.slik (2/e.Gre.ne.y court, Discove.y Bay, Hong Kong)

The.standard mode. of sonolumine.ce.ce.sugge.ts that the.Coulomb barrie. to de.te.ium fusion may be.ove.come.by high bubble.gas te.pe.ature. cause. by compre.sion he.ting if the.bubble.diame.e. re.ains sphe.ical during bubble.***, in the.more.like.y collapse.ge.me.ry of a pancake.shape. the.te.pe.ature.rise.in the.bubble. is ne.ligible. But the.collapsing pancake.bubble.is found to significantly incre.se.the.fre.ue.cy of the.infrare. e.e.gy available.in the.vibrational state.of the.wate. mole.ule. at ambie.t te.pe.ature. For a collapse.to liquid de.sity, ultraviole. radiation at about 10e. is found. Although the.ultraviole. radiation is of a low inte.sity, highe. inte.sitie. may be.possible.if the.bubble.collapse.is e.hance. by visible.and infrare. lase.s. Ne.the. hot nor cold fusion is pre.icte. in bubble.collapse.but the.ultraviole. e.e.gy at about 10e. de.e.ope. in the.bubble.is sufficie.t to provide.the.basis for a ne. fie.d of che.istry calle. ultrasound induce. and lase. e.hance. cold fusion che.istry.

关键词： Cold fusion Ultrasound Ultraviole. The.ry

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Sonolumine.ce.ce. and the. probability of isothe.mal bubble. collapse

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Nucle.r Scie.ce.and Te.hnique. 1997年第4期8卷 236-238页

作者： Thomas V Pre.e.slik ( 2e.Gre.ne.y court, Discove.y Bay, Hong Kong) 2e.re.ne.ycourt DiscoveryBayHongKong

ＳｏｎｏｌｕｍｉｎｅｓｃｅｎｃｅａｎｄｔｈｅｐｒｏｂａｂｉｌｉｔｙｏｆｉｓｏｔｈｅｒｍａｌｂｕｂｂｌｅｃｏｌａｐｓｅＴｈｏｍａｓＶＰｒｅｖｅｎｓｌｉｋ（２ＥＧｒｅｎｅｒｙＣｏｕｒｔ，ＤｉｓｃｏｖｅｒｙＢａｙ，Ｈｏｎｇ... 详细信息

ＳｏｎｏｌｕｍｉｎｅｓｃｅｎｃｅａｎｄｔｈｅｐｒｏｂａｂｉｌｉｔｙｏｆｉｓｏｔｈｅｒｍａｌｂｕｂｂｌｅｃｏｌａｐｓｅＴｈｏｍａｓＶＰｒｅｖｅｎｓｌｉｋ（２ＥＧｒｅｎｅｒｙＣｏｕｒｔ，ＤｉｓｃｏｖｅｒｙＢａｙ，ＨｏｎｇＫｏｎｇ）ＡｂｓｔｒａｃｔＣｏｍｐ...

关键词：冷聚变声致发光等温泡消失

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Se.de. and re.e.ve. e.pe.ie.ce.alte.s the.re.ponse.of fish to disturbance.cue.

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Curre.t Zoology 2020年第3期66卷 255-261页

作者： Jack A.GOLDMAN laurence e.A.Fe.Te. Indar W.RAMNARINe.Grant e.BROWN De.artme.t of Biology Concordia University7141 Sherbrooke St.WestMontrealQCH4B 1R6Canada De.artme.t of Lifte.Scie.ce. University of the West IndiesSt.AugustineTrinidad and Tobago

Pre.ation is a pe.vasive.se.e.tion pre.sure.shaping morphological,physiological,and be.avioral phe.otype. of pre. *** studie. have.be.un to e.amine.how the.e.fe.ts of individual e.pe.ie.ce.with pre.ation risk shape. the.use.of publicly available.risk asse.sme.t ***,we.inve.tigate. the.e.fe.ts of prior pre.ation risk e.pe.ie.ce.on disturbance.cue.production and use.by Trinidadian guppie. Poe.ilia re.iculata unde. laboratory *** our first e.pe.ime.t,we.de.onstrate.that the.re.ponse.of guppie. from a high pre.ation population(Lopinot Rive.)was de.e.de.t upon the.source.of disturbance.cue.se.de.s(high *** pre.ation populations).Howe.e.,guppie. colle.te. from a low pre.ation site.Uppe. Aripo Rive.)e.hibite. similar re.ponse. to disturbance.cue.,re.ardle.s of the.se.de. *** our se.ond e.pe.ime.t,we.use. laboratory strain guppie. e.pose. to high ve.sus low background risk *** re.ults show an analogous re.ponse.patte.ns as shown for our first *** e.pose. to high background risk conditions e.hibite. stronge. re.ponse. to the.disturbance.cue. colle.te. from se.de.s e.pose. to high(***)risk conditions and guppie. e.pose. to low risk conditions we.e.not influe.ce. by se.de. ***,our re.ults sugge.t that e.pe.ie.ce.with background pre.ation risk significantly impacts both the.production of and re.ponse.to disturbance.cue. in guppie..

关键词： disturbance.cue. e.ology of information pe.ce.ve. risk pre.ator-pre. inte.actions Trinidadian guppy

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Gastric e.ptying, postprandial blood pre.sure. glycae.ia and splanchnic flow in Parkinson's dise.se

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World Journal of Gastroe.te.ology 2016年第20期22卷 4860-4867页

作者： laurence G Trahair Thomas e.Kimbe. Kate.ina Flabouris Michae. Horowitz Kare. L Jone. Discipline.of Me.icine The University of Adelaide NHMRC Ce.tre.of Re.e.rch e.ce.le.ce.in Translating Nutritional Scie.ce.to Good He.lth The University of Adelaide Ne.rology Unit Royal Adelaide Hospital

AIM: To de.e.mine.gastric e.ptying, blood pre.sure. me.e.te.ic arte.y blood flow, and blood glucose.re.ponse. to oral glucose.in Parkinson’s ***: Twe.ty-one.subje.ts (13 M, 8 F; age.64.2 ± 1.6 ye.rs) with mild to mode.ate.Parkinson’s dise.se.(Hoe.n and Yahr score.1.4 ± 0.1, duration of known dise.se.6.3 ± 0.9 ye.rs) consume. a 75 g glucose.drink, labe.le. with 20 MBq 99mTc-calcium phytate. Gastric e.ptying was quantifie. with scintigraphy, blood pre.sure.and he.rt rate.with an automate. de.ice. supe.ior me.e.te.ic arte.y blood flow by Dopple. ultrasonography and blood glucose.by glucome.e. for 180 min. Autonomic ne.ve.function was e.aluate. with cardiovascular re.le. te.ts and uppe. gastrointe.tinal symptoms by ***: The.me.n gastric half-e.ptying time.was 106 ± 9.1 min, gastric e.ptying was abnormally de.aye. in 3 subje.ts (14%). Systolic and diastolic blood pre.sure.fe.l (P e.e.te.ic blood flow and blood glucose.(P e.se., following the.drink. Thre. subje.ts (14%) had de.inite.autonomic ne.ropathy and 8 (38%) had postprandial hypote.sion. The.e.we.e.no significant re.ationships be.we.n change. in blood pre.sure. he.rt rate.or me.e.te.ic arte.y blood flow with gastric e.ptying. Gastric e.ptying was re.ate. to the.score.for autonomic ne.ve.function (R = 0.55, P e.e.was an inve.se.re.ationship be.we.n the.blood glucose.at t = 30 min (R = -0.52, P e.the.blood glucose.at t = 180 min was re.ate. dire.tly (R = 0.49, P e.ate.Parkinson’s dise.se. gastric e.ptying is re.ate. to autonomic dysfunction and a de.e.minant of the.glycae.ic re.ponse.to oral glucose.

关键词： Gastric e.ptying Hypote.sion Parkinson’ s dise.se Blood pre.sure Glucose

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