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Congenital Toxoplasmosis or the Tip of an Iceberg. Report of Two Cases

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Open Journal of Pediatrics 2022年第1期12卷 213-222页

作者： Kisito Nagalo Sonia Kaboret laure Toguyéni Auguste Attoh Aïssatou Bélemviré Myriam Sanwidi Balkissa Konaté Carine Kyélem Diarra Yé Unité de néonatologie Centre Hospitalier Universitaire Pédiatrique Charles de Gaulle Ouagadougou Burkina Faso

Among the many parasitic diseases observed in the tropics, Toxoplasmosis is a fairly common occurrence. An infected pregnant woman can transmit it, transplacentally, to her foetus. Two cases of congenital toxoplasmosis are discussed in this study. One patient is at 7 days of life, while the other is at 9 days of life. The newborns displayed the typical symptoms of jaundice, hepatosplenomegaly, chorioretinitis, and cranioencephalic abnormalities. However, the uniqueness of these observations is the presence of umbilical haemorrhage, a symptom not described in the literature researched. The evolution of this finding, during treatment is distinguished by the symptoms persisting until six months of age, in addition to growth retardation of saturation-weight, with no retardation of psychomotor development in one patient, and with hydrocephalus accompanied by psychomotor retardation in the other one. Hence, it is recommended that pregnant women are systematically screened for toxoplasmosis, and seronegative women are monitored;in fact, the early and suitable management of congenital toxoplasmosis will significantly control this parasitosis.

关键词： Toxoplasmosis Congenital Toxoplasmosis Toxoplasma gondii Embryo-Fetopathy TORCH Infections

人类化的物与怪异的物：论物在叙事中的主动作用

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江西社会科学 2020年第1期40卷 133-141,255页

作者：玛丽-劳拉·瑞安唐伟胜江西师范大学外国语学院

思辨实在论和相关哲学流派开始转向对非人类进行本体思考,叙事研究应该对此作出反应。通过对奥罕·帕慕克的《纯真博物馆》和萨特的《恶心》进行细读,本文提出"物"在叙事中有两种基本处理方式:人类化的物及怪异的物。在《纯真博物馆》中... 详细信息

思辨实在论和相关哲学流派开始转向对非人类进行本体思考,叙事研究应该对此作出反应。通过对奥罕·帕慕克的《纯真博物馆》和萨特的《恶心》进行细读,本文提出"物"在叙事中有两种基本处理方式:人类化的物及怪异的物。在《纯真博物馆》中,男主人公凯末尔试图在物件和人类之间建立一种情感联系,通过物件来找回逝去的爱情,体现了一种典型的"恋物癖";而在《恶心》中,主人公罗康坦却注意到了物独立于人类而存在的怪异性,并从这怪异的物中顿悟了存在的多余。

关键词：人类化的物怪异的物《纯真博物馆》《恶心》

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杂交:进化新动力

新发现 2019年第12期 54-58页

作者： Anne-laure Thadee 王佳蕾(编译) 不详

无论是动物还是植物,杂交种过去一直被视为怪胎甚至异类。然而研究表明,再罕见的杂交也在进化中发挥了举足轻重的作用。DNA开口说话了。1990年代初一次格陵兰岛科考任务期间,鲸类专家迈兹·彼得·海德-约根森(Mails Peter Heide-jorgens... 详细信息

无论是动物还是植物,杂交种过去一直被视为怪胎甚至异类。然而研究表明,再罕见的杂交也在进化中发挥了举足轻重的作用。DNA开口说话了。1990年代初一次格陵兰岛科考任务期间,鲸类专家迈兹·彼得·海德-约根森(Mails Peter Heide-jorgensen)在一个因纽特人的棚屋顶发现了一具悬挂着的鲸类颅骨。彼时,他对眼前所见深感疑惑。日前,分子生态学教授艾琳·劳伦森(Eline Lorenzen)团队通过基因分析揭开了这其中的奥妙。

关键词：因纽特人基因分析开口说话分子生态学格陵兰岛新动力

Community-Based Approach in the Prevention and Management of Flood Disasters in Babessi Sub-Division (Ndop Plain, North West Cameroon)

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Journal of Geoscience and Environment Protection 2018年第4期6卷 211-228页

作者： Pamela Aka Tangan Primus Azinwi Tamfuh Alice Magha Mufur Evine laure Tanko Njiosseu Jules Nfor Aminatou Fagny Mefire Dieudonné Bitom Department of Geology Mining and Environmental Sciences Faculty of Science The University of Bamenda Bambili Cameroon Department of Soil Science Faculty of Agronomy and Agricultural Sciences University of Dschang Dschang Cameroon Department of Geology Higher Teacher Training College The University of Bamenda Bambili Cameroon Department of Geology Faculty of Science The University of Dschang Dschang Cameroon

Flood is a recurrent natural disaster that has caused enormous human and material damage in many places and continues to hit local committees at an alarming rate. The need to setup permanent committees to prevent and manage flood disasters by local communities is therefore indispensable. In rural areas, the creation of such a structure is always a welcome relief to flood victims but it is often marred by numerous management problems. This study aimed to analyze the community-based approach in the prevention and management of flood disasters in Babessi Subdivision (North West Cameroon), to identify the causes of flood disasters and the preventive strategies used by this local community. A total number of 300 questionnaires as well as structured interviews were used to collect data in the field and the data were analyzed by simple descriptive statistics. The main results revealed that the main cause of flood disasters is heavy and consistent rainfall. Also, poor refuse disposal and drainage system management contribute to floods. The identification of areas likely to be affected by floods and preventing the riparian population from constructing houses along these areas especially beside the main rivers are the flood preventive measures adopted by the local flood management committee. The flood victims are reluctant to relocate to the settlement site earmarked by the Government, meanwhile, the local flood committee do not have the legal tools to forcefully relocate them. The population of Babessi needs to be sensitized on the impending dangers of flood hazard and be encouraged to participate in implementing the adopted strategies to prevent and manage subsequent flood disasters.

关键词： Disaster Management Flood Community-Based Approach Ndop Plain North West Cameroon

Abundance and Source Identification of Polycyclic Aromatic Hydrocarbons in Sediments of the Ivory Coastal Zone (Toukouzou Hozalem-Assinie)

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American Journal of Analytical Chemistry 2023年第1期14卷 12-27页

作者： laure Emma Oura Vanh Eric-Simon Zran Georges Kouadio Horo Koné Affoué Tindo Sylvie Konan Albert Trokourey Kouassi Benjamin Yao Fofana Bakary Laboratoire des Procédés Industriels de Synthèse de l’Environnement et des Energies Nouvelles (LAPISEN) de l’Institut National Polytechnique Félix Houphouë t Boigny de Yamoussoukro Yamoussoukro C&ocirc te d’Ivoire Centre Analyses et Recherche (CAR) Petroci Holding Abidjan C&ocirc te d’Ivoire Laboratoire de Constitution et Réaction de la Matière (LCRM) Université Félix Houphouet Boigny Abidjan Cote d’Ivoire Department of Science and Technology Université Alassane Ouattara de Bouaké Bouaké C&ocirc te d’Ivoire Laboratoire de Thermodynamique et de Physico Chimie du Milieu Université Nangui Abrogoua Abidjan C&ocirc te d’Ivoire Centre D’Analyse et de Recherche de la PETROCI (DCAR) Cô te d’Ivoire. Immeuble les Hevéas-14 Bd Carde Abidjan Cote d’Ivoire

Polycyclic aromatic hydrocarbons (PAHs) are strongly associated with agricultural, residential, transportation, industrial and petroleum activities. In this study, the presence of PAHs (polycyclic aromatic hydrocarbons) was investigated in sediments of the ivory coastal zone (Toukouzou Hozalem-Assinie). The main objectives of this study were to determine the abundance and to predict the source of PAHs in the sediments. Gas chromatography-mass spectrometry (GC-MS) was used to analyze sixteen priority PAHs. Total PAHs concentrations were from 1.31 to 3992.68 mg/kg in sediment with an average concentration of (307.54 ± 16.10) mg/kg. Among all PAHs, Naphthalene (Nap = 332.72 mg/kg) and Phenanthrene (Phe = 41.75 mg/kg) were found in the highest concentration, whereas Benzo (k) Fluoranthene was found in the least concentration in the range of 0 - 0.85 mg/kg (mean 0.24 mg/kg). Bassam-Modeste Lagune (BML) sampling site was the site with the highest concentration of total PAHs (all 16 PAHs) compared to the others due to their location in a highly populated estuary area that receives commercial, tourism, port, petroleum and heavy industrial activities. Diagnostic ratios were used to determine the sources of PAHs and suggested that the PAH profile in the sediments was dominated by 2 and 3 ring PAHs. The patterns of PAH compounds in sediment indicated that contamination is from mixed sources, with a strong indication of petrogenic contamination potentially from spills of fuel, oil and industrial activities.

关键词： Polycyclic Aromatic Hydrocarbons Sediment Source Abundance Ivorian Coastal

Pregnancy Air Exposure: An R Package for Estimation of Exposure to Air Pollution during Critical Windows of Pregnancy

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Open Journal of Statistics 2017年第3期7卷 422-433页

作者： Séverine Deguen laure Nicollet Morgane Gilles Arlette Danzon Olivier Blanchard Géraldine Le Nir Denis Zmirou-Navier Wahida Kihal-Talantikite EHESP School of Public Health Rennes France Maternal and Infant Preventive Institute (PMI) Paris France Air Quality Monitoring Associations (AASQA) Airparif Paris France INSERM U1085 IRSET (Research Institute in Environmental and Occupational Health) Rennes France Lorraine University Medical School Nancy France University of Strasbourg CNRS LIVE UMR 7362 Strasbourg France

Today, it is well known that ambient air pollution exposures may be related with different health outcomes including adverse birth outcomes (for instance, low birth weight and preterm birth). Then, researchers must estimate exposure to air pollution during different critical windows of exposure across pregnancy. In the literature, the most commonly examined critical windows of exposure are the first, second, and third trimesters of pregnancy, although the entire pregnancy is also studied. In this context, we developed an automatic procedure which estimates individual exposures by trimester. We illustrate usage of the Pregnancy Air Exposure package for all births within the city of Paris in 2011. Nitrogen dioxide data from monitoring stations and data modeled at the census block level were available from the air quality monitoring networks of Ile de France Region. Nitrogen dioxide, NO2, has been chosen as an indicator of traffic-generated pollution. Newborn health data are available from the first birth certificate registered by the Maternal and Child Care department of Paris;more specifically, we used the date of birth and the gestational age to individually determine the beginning and the end of each trimester. The Pregnancy Air Exposure R package was created to simplify application of the procedure for non-specialists, and is freely available from the Equit’Area project website: (***/documents/package_Exposure). The package contains two functions as well as the help files needed to run the procedure and yields air pollution exposure estimates by pregnancy trimester. The two functions can be used successively or independently according to the available input data.

关键词： Air Pollution Exposure Pregnant Women Critical Window of Exposure R Software

Diagnostic Performance of Five Rapid Serological Tests for SARS-CoV-2

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Open Journal of Epidemiology 2022年第4期12卷 470-480页

作者： Gilbert Ndziessi Jospeh Axel Ngatse Fabien Roch Niama Henriette Poaty Mayengue Pembe Issamou Fresnovie Geladore Mbele laure Stella Ghoma Linguissi Francine Ntoumi Department of Public Health Faculty of Health Sciences University Marien Ngouabi Brazzaville Republic of the Congo National Laboratory of Public Health Brazzaville Republic of the Congo National Research Institute on Health Sciences Brazzaville Republic of the Congo Fondation Congolaise pour la Recherche Médicale Brazzaville Republic of the Congo

We conducted a study to evaluate the sensitivity (Se), specificity (Sp), positive predictive value (PPV), and negative predictive value (NPV) of five serologic tests. Subjects with negative or positive COVID-19 polymerase chain reaction (PRC) test results were tested with each of the serological tests. The results were compared with the reference PCR test. For the five tests evaluated, the Se ranged from 55.0% to 70.0% and the Sp ranged from 67.2% to 86.2%. PPV ranged from 53.2% to 80% and NPV from 75.0% to 86.2%. One test, the Wantai, had better specificity and sensitivity. None of the five tests had performance values of more than 90% in the entire sample. In symptomatic positive cases, the Wantai test reported excellent sensitivity. Overall, the low level of diagnostic performance of these tests does not support their use as an alternative to PCR for COVID-19 diagnostic. Test with better performance can be used for mass screening in low prevalence populations, to limit the indiscriminate use of PCR in context of resource-limited countries. Given the excellent sensitivity of Wantai in symptomatic cases, this test could be used as a referral test only in health facilities to discriminate suspected cases before PCR confirmation.

关键词： SARS-Cov-2 Seroprevalence Antibodies COVID-19 Congo

Potential Association between Anterior Cruciate Ligament Tear and “Bi-Collateral” Ligamentous Rupture: A Retrospective Study

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Open Journal of Radiology 2015年第4期5卷 217-223页

作者： Jean Roger Moulion Tapouh Boniface Moifo Cathy Monabang Zoé Marc Leroy Guifo Haoua Tebere Annick laure Edzimbi Samuel Nko’o Amvene Department of Radiology and Radiation Oncology Faculty of Medicine and Biomedical Sciences (FMBS) The University of Yaoundé I Yaounde Cameroon Yaounde Gynaeco-Obstetric and Pediatric Hospital (YGOPH) Yaounde Cameroon Yaounde University Teaching Hospital Yaounde Cameroon Department of Surgery and Sub-Specialties (FMBS) Yaounde Cameroon

Background: Anterior cruciate ligament (ACL) tears are common complications of knee trauma. This entity can be reliably diagnosed by Magnetic Resonance Imaging. There is a lack of data on the epidemiology of ACL tears in Sub-Saharan Africa. The aim of this study is to describe the radiological aspects of post traumatic ACL tears in a black African setting (Yaounde Teaching Hospital). Methods: ninety six (96) MR studies of the knee were retrospectively reviewed. They were realized on a low field device (0.2T) from July 2012 to December 2013. All the examinations were indicated for knee trauma. Ligamentous, meniscal, bony and joint lesions were sought on coronal and sagittal sections. Results: the sample consists of 70% (68/96) of men. The mean age is 35.36 ± 11.86 years. The prevalence of ACL tears is 45.8% (44/96) of which 36 (81.81%, 36/44) are total tears. 23 (24%) have associated meniscal lesion and 8 (8.3%) have a simultaneous damage of the collateral ligaments. The most frequently injured part of the meniscus is its posterior horn (12/23 cases). Meniscal and “bi-collateral” ligament injuries are independently associated to ACL tears. Conclusion: The prevalence of ACL tears at the Yaounde Teaching Hospital is 45.8%. It is independently associated to meniscal tears and concomitant injury of the tibial and fibular collateral ligaments.

关键词： Anterior Cruciate Ligament Magnetic Resonance Imaging Meniscal Tears Knee Trauma

Feasibility of iFISH patterns in hematologic malignancies among Congolese patients at Kinshasa University clinics

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Asian Pacific Journal of Tropical Biomedicine 2017年第12期7卷 1116-1119页

作者： Mireille Solange Nganga Nkanga Benjamin Longo-Mbenza Peter Vandenberghe Fons Verdonck Venant Tchokonte-Nana Nkama Claude Nlandu Roth laure Mapapa Miakassissa Paul Roger Beia Kazadi Antoine Lufimbo Katawandja Jacques Bikaula Ngwidiwo Ntolo Jean-Pierre Mufuta Kuanda Thomas Solo Mbombo Aurore Cecilia Orphée Beia Faculty of Medicine University of Kinshasa University President Kasa Vubu UZ Gasthuisberg/KU Leuven Faculty of Medicine and Health Sciences Stellenbosch University Pediatric Services University Hospital of Brazzaville OVD Hospital Center Ngaliema Clinic Regional Center of Nuclear Studies of Kinshasa University of Kinshasa

Objective: To analyze the feasibility of detecting Ph1 in leukemia patients in the Kinshasa University Clinics in the Democratic Republic of Congo, at KU Leuven, ***: Bone marrow and peripheral blood samples with chronic myeloid leukemia,acute myeloid leukemia or acute leukocytes leukemia were obtained from 32 patients in Kinshasa University clinics in the Democratic Republic of Congo and transferred to KU Leuven in Belgium for i FISH feasibility. Ph^1 was detected by using a remote analysis of interphase fluorescence in situ hybridization(i FISH).Results: Out of the 32 patients involved in this study, 65.6%(n = 21) of the cases were successfully tested, of which 52.4%(n = 11) were i FISH positives for the variant t(9;22)(presence of Ph^1) in chronic myeloid leukemia samples and 47.6%(n = 10) negatives in all subtypes of hematological malignancies. However, there was a female predominance in chronic myeloid leukemia samples Ph^1-positives by i FISH, whereas no sexual influence was observed on acute subtypes of ***: i FISH analysis is feasible on samples obtained from remote sites in the Democratic Republic of Congo. However, the optimization of the sample storage is necessary to further improve i FISH's performance.

关键词： iFISH Ph^1 Democratic Republic of Congo Leukemia Bone marrow Blood