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Pharmacological inhibition of cannabinoid receptor 1 stimulates gastric release of nesfatin-1 via the mTOR pathway

World Journal of Gastroenterology 2017年第35期23卷 6403-6411页

作者： Cintia Folgueira Silvia Barja-Fernandez laura Prado Omar Al-Massadi Cecilia Castelao Veronica Pena-Leon Patricia Gonzalez-Saenz Javier Baltar Ivan Baamonde rosaura Leis Carlos Dieguez Uberto Pagotto Felipe F Casanueva Sulay A Tovar Ruben Nogueiras Luisa M Seoane Grupo Fisiopatología Endocrina Instituto de Investigación Sanitaria de Santiago de Compostela CIBER Fisiopatología Obesidad y Nutrición Instituto de Salud Carlos III department of Physiology Research Centre of Molecular Medicine and Chronic Diseases department of Pediatric Universidad de Santiago de Compostela Servicio de Cirugía General Complexo Hospitalario Universitario de Santiago Endocrinology Unit and Center for Applied Biomedical Research Department of Medical and Surgical SciencesHospital S.Orsola-MalpighiAlma Mater University of Bologna laboratorio de Endocrinología Molecular y Celular.Universidad de Santiago de Compostela Instituto de Investigación Sanitaria de Santiago de CompostelaComplexo Hospitalario Universitario de Santiago

AIM To determine whether Nucb2/nesfatin1 production is regulated by the cannabinoid system through the intracellular m TOR pathway in the *** Sprague Dawley rats were treated with vehicle, rimonabant, rapamycin or rapamycin+rimonabant. Gastric tissue obtained from the animals was used for biochemical assays: Nucb2 m RNA measurement by real time PCR, gastric Nucb2/nesfatin protein content by western blot, and gastric explants to obtain gastric secretomes. Nucb2/nesfatin levels were measured in gastric secretomes and plasma using enzyme-linked immunosorbent assay. RESULTS The inhibition of cannabinoid receptor 1(CB1) by the peripheral injection of an inverse agonist, namely rimonabant, decreases food intake and increases the gastric secretion and circulating levels of Nucb2/nesfatin-1. In addition, rimonabant treatment activates m TOR pathway in the stomach as showed by the increase in pm TOR/m TOR expression in gastric tissue obtained from rimonabant treated animals. These effects were confirmed by the use of a CB1 antagonist, AM281. When the intracellular pathway m TOR/S6 k was inactivated by chronic treatment with rapamycin, rimonabant treatment was no longer able to stimulate the gastric secretion of Nucb2/*** The peripheral cannabinoid system regulates food intake through a mechanism that implies gastric production and release of Nucb2/Nesfatin-1, which is mediated by the m TOR/S6 k pathway.

关键词： NUCB2/nesfatin-1 Stomach Food intake Cannabinoid receptor 1 mTOR

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land-use change and windstorms legacies drove the recolonization dynamics of laurel forests in Tenerife, Canary islands

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Forest Ecosystems 2023年第1期10卷 113-124页

作者： Vicente Rozas Maria A.Garcia-Lopez Jose M.Olano Gabriel Sanguesa-Barreda Miguel Garcia-Hidalgo Susana Gomez-Gonzalez Roberto Lopez-Rubio Jose M.Fernandez-Palacios Ignacio Garcia-Gonzalez laura Lozano-Lopez Paula Garcia-Gonzalez Ana I.Garcia-Cervigon EiFAB-iuFOR Universidad de ValladolidCampus Duques de Soria42004SoriaSpain departamento de Biologia-IVAGRO Universidad de CadizCampus Rio San Pedro11510Puerto RealSpain Center for Climate and Resilience Research(CR)2 Blanco Encalada 20028370449SantiagoChile Area de Biodiversidad y Conservacion Universidad Rey Juan Carlosc/Tulipan s/n28933MostolesSpain Grupo de Ecologia y Biogeografia Insular Universidad de La Laguna38206La LagunaTenerifeSpain BIOAPLIC Departamento de BotanicaEscola Politecnica Superior de EnxenariaCampus TerraUniversidade de Santiago de CompostelaLugo27002Spain

laurel forests are quite relevant for biodiversity conservation and are among the island ecosystems most severely damaged by human *** the past,Canary laurel forests have been greatly altered by logging,livestock and *** remains of laurel forests are currently protected in the Canary Islands(Spain).However,we miss basic information needed for their restoration and adaptive management,such as tree longevity,growth potential and responsiveness to natural and anthropogenic *** dendrochronological methods,we studied how forest dynamic is related to land-use change and windstorms in two well-preserved laurel forests on Tenerife *** cores were collected from over 80 trees per stand at three stands per *** used ring-width series to estimate tree ages and calculate annual basal area increments(BAI),cumulative diameter increases,and changes indicative of released and suppressed *** tree species were found in all stands,with laurus novocanariensis,Ilex canariensis and Morella faya being the most common *** some individuals were over 100 years old,61.8%-88.9% of the trees per stand established between 1940 and 1970,coinciding with a post-war period of land abandonment,rural exodus and the onset of a tourism *** trees have shown growth rates larger than 1 cm diameter per year and most species have had increasing BAI trends over the past *** growth releases occurred after windstorms at both sites,but the effects of windstorms were site-dependent,with the 1958 storm affecting mainly the eastern tip of the island(Anaga massif)and the 1991 storm the western tip(Teno massif).Given the great ability of laurel forest trees to establish after land use cessation and to increase growth after local disturbances such as windstorms,passive restoration may be sufficient to regenerate this habitat in currently degraded areas.

关键词： Canary islands dendroecology Disturbance Forest structure Macaronesia Management cessation Tree rings

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Nutritional,Antioxidant and Anti-Inflammatory Properties of Cyclanthera pedata,an Andinean Fruit and Products derived from Them

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Food and Nutrition Sciences 2013年第8期4卷 55-61页

作者： Marisa Rivas Dora Vignale Roxana M.Ordonez Iris Catiana Zampini María rosa Alberto Jorge E.Sayago María I.Isla INQUINOA(CONICET) TucumánArgentina Cátedra de Botánica Sistemática y Fitogeografía Facultad de Ciencias AgrariasUniversidad Nacional de JujuyAlberdiSan Salvador de JujuyArgentina Cátedra de Elementos de Química Orgánica y Biológica Facultad de Ciencias Naturales e Instituto Miguel LilloTucumánArgentina Cátedra de Fitoquímica Facultad de BioquímicaQuímica y FarmaciaUniversidad Nacional de Tucumán(4000)S.M.de TucumánTucumánArgentina Fundación Miguel Lillo TucumánArgentina

There is an increasing interest in food plant with health-giving effects. The aim of this research was to evaluate the phytochemical and nutraceutical profiles of Cyclanthera pedata fruits, a native fruit of the Andean region used by Incas communities called achojcha. Soluble protein (SP), total sugar (TS), free phenolic compounds (FPC), ascorbic acid (AA), total monomeric anthocyanin (TMA), condensed and hydrolizable tannin (CT, HT) were evaluated by sprectrophotometric methods in fresh fruits with and without heating and in flour obtained from fruits. Multielemental composition by ICP-MS was done. Antioxidant activity (AOA) was determined by ABTS and Linoleic acid-b-carotene methods. The inhibitory capacity of LOX, a pro-inflammatory enzyme was also analyzed. The achojcha fresh fruits and achojcha flour showed low amount calories. The flour was high in potassium (7400 mg·K/100 g) and low in sodium (77 mg Na/100 g). High levels of FPC (670 mg GAE/100 g) were found together with elevated levels of AA (123 mg AA/ 100 g). The TMA (0.6 mg C3-GE/100 g) as well as HT (3.4 mg PB2E/100 g) were also detected in flour. All preparations obtained with fresh and dried fruits showed AOA with SC50 values between 1.8 to 14.5 μg GAE/mL. Inhibitory capacity on LOX was also demonstrated (IC50 values of 40 μg GAE/mL). The fresh fruits and flour showed nutraceutical characteristics that are demanded by functional food and could be used as dietary supplement.

关键词： achojcha Fruit achojcha Flour Cyclanthera pedata Nutritional Properties Functional Properties

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Prevalence of Potential Drug-Drug Interactions in Hospitalized Surgical Patients

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Journal of Pharmacy and Pharmacology 2016年第12期4卷 658-666页

作者： Virginia Aleyda Sanchez-Lopez Lorena Michele Brennan-Bourdon Ana rosa Rincon-Sanchez Maria CristinaIslas-Carbajal Andres Navarro-Ruiz Selene Guadalupe Huerta-Olvera departamento de Fisiologia Centro Universitario de Ciencias de la Salud Universidad de Guadalajara Guadalajara 44340Jalisco Mdxico Comisi6n para la Protecci6n contra Riesgos Sanitarios del Estado de Jalisco (COPRISJAL) Guadalajara 44500 Jalisco Mdxico departamento de Biologia Molecular y Genomica Centro Universitario de Ciencias de la Salud Universidad de GuadalajaraGuadalajara 44340 Jalisco Mexico Servicio de Farmacia Hospital General Universitario de Elche Elche (Alicante) 03203 Spain departamento de Ciencias Medicas y de la Vida Centro Universitario de la Cienega Universidad de Guadalajara Ocotlan47820 Jalisco. Mexico

The objective of this study is to estimate the prevalence and describe the characteristics of pDDIs （potential drug-drug interactions） in medical prescriptions of hospitalized surgical patients. In this cross-sectional study, we analyzed 370 medical prescriptions from the surgery unit of a Mexican public teaching hospital. The identification and classification of potential drug-drug interactions were performed with the Micromedex 2.0 electronic drug information database. Results were analyzed with descriptive statistics and we estimated OR （odds ratio） to determine associated risk factors. From the study, it was found that the prevalence of potential drug-drug interactions was 45.9%. A total of 385 interactions were identified. Of these, 54.3% were classified as major and 60.5% as pharmacodynamic. Prescriptions for more than seven drugs （OR =7.33, CI （confidence interval） = 4.59-11.71） and advanced age 〉 60 years, （OR = 1.79, CI = 1.06-2.74） were positively associated with the presence of potential drug-drug interactions. We found a high prevalence of clinically relevant pDDIs in the surgery unit. In view of this outcome, the safety of drug combinations in hospitalized surgical patients should be evaluated during the prescription process in order to prevent adverse events.

关键词： Potential drug-drug interactions medical prescriptions concomitant drugs surgery.

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Agronomic Use of Slurry from Anaerobic Digestion of Agroindustrial Residues: Effects on Crop and Soil

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Journal of Sustainable Bioenergy Systems 2014年第1期4卷 87-96页

作者： Amabelia del Pino Omar Casanova Mónica Barbazán Victoria Mancassola laura Arló Liliana Borzacconi Mauricio Passeggi departamento de Ingeniería de Reactores Facultad de Ingeniería Universidad de la República Montevideo Uruguay departamento de Suelos y Aguas Facultad de Agronomía Universidad de la República Montevideo Uruguay

In a greenhouse experiment we evaluated the application of slurry generated by a biogas reactor of agroindustrial residues. The objectives of this study were to determine the response to slurry application on dry matter production and nutrients absorption of Setaria italica (setaria), and to evaluate the effect of the slurry on soil properties. Two soils, of different texture, were mixed either with slurry or with diammonium phofsphate (DAP) at 0, 80, and160 kgN ha-1 equivalent rates. The setaria was harvested 68 days after planting, and separated into leaves plus stems, ears, and roots. Total biomass and content of N, P, K, Ca, Mg, Cu, Fe, Mn, and Zn were determined in each fraction. In the soil we determined pH, electric conductivity (EC), organic C, available P, mineral N, and exchangeable cations. Although the biomass produced and the amounts of nutrients absorbed were different in the two soils, in both of them setaria responded to the slurry application. The amounts of N absorbed from slurry and DAP were similar, indicating that the N from the slurry was readily available. The slurry application also increased the absorption of other macro and micro nutrients (P, Ca, Mg, and Zn). No significant changes in soil exchangeable cations, pH, and EC were observed at setaria harvest. In the silty soil the crop almost depleted the mineral N in all treatments, but in the sandy soil large amounts were left, especially in the treatments with slurry. This fact highlights the importance of a careful dosage of this soil amendment, to avoid the excess of mineral N, which is potential pollutant for the environment. It can be concluded that the use of slurry from the reactor had a positive effect on the nutrients availability, without negative effects on soil properties.

关键词： Biosolids Biogas Slurry Setaria Italica Uruguay

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Metabolic dysregulation in term infants from SARS-CoV-2-infected mothers

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World Journal of Pediatrics 2023年第9期19卷 912-917页

作者： Mari Merce Cascant-Vilaplana Inmaculada lara-Cantón Victoria Ramos-Garcia Alejandro Pinilla-González Álvaro Solaz-García Guillermo Quintás Purificación Marín-Reina Marta Aguar laura Torrejón-Rodríguez Máximo Vento Julia Kuligowski María Cernada Neonatal Research Unit Health Research Institute Hospital La FeUniversity Polytechnic Hospital La FeAvda.Fernando Abril Martorell 10646026ValenciaSpain Leitat Technological Center ValenciaSpain Analytical Unit Health Research Institute La FeValenciaSpain Division of Neonatology University and Polytechnic Hospital La FeValenciaSpain

Severe acute respiratory syndrome coronavirus 2(SARSCoV-2)is a novel beta coronavirus that causes coronavirus disease 2019(COVID-19),a severe infectious respiratory *** January 2020,the World Health Organization(WHO)d... 详细信息

关键词： mother respiratory acute

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Energy modeling and data structure framework for Sustainable Human-Building Ecosystems （SHBE）- a review

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Frontiers in Energy 2018年第2期12卷 314-332页

作者： Suraj TALELE Caleb TRAYLOR laura ARPAN Cali CURLEY Chien-Fei CHEN Julia DAY Richard FEIOCK Mirsad HADZIKADIC William J. TOLONE Stan INGMAN Dale YEATTS Omer T. KARAGUZEL Khee Poh laM Carol MENASSA Svetlana PEVNITSKAYA Thomas SPIEGELHALTER Wei YAN Yimin ZHU Yong X. TAO department of Mechanical and Energy Engineering University of North Texas Denton Texas 76203 USA College of Communication & Information Florida State University Tallahassee FL 32306 USA School of Public and Environmental Affairs Indiana University-Purdue University Indianapolis Indianapolis 1N 46202 USA department of Sociology University of Tennessee Knoxville Knoxville TN 37996 USA Human Ecology Department of Construction Management Washington State University Pullman WA 99164 USA Reubin O'D. Askew School of Public Administration and Policy Florida State University Tallahassee FL 32306 USA College of Computing and Informatics University of North Carolina Charlotte Charlotte NC 28223 USA department of Gerontology University of North Texas Denton TX 76203 USA department of Gerontology and department of Sociology University of North Texas Denton TX 76203 USA CMU School of Architecture Carnegie Mellon University Pittsburgh PA 15213 USA School of design & Environment National University of Singapore Singapore 117566 Singapore department of Civil and Environmental Engineering University of Michigan Ann Arbor MI 48109 USA department of Economics Florida State University Tallahassee FL 32306 USA department of Architecture Florida Intemational University Miami FL 33199 USA College of Architecture Texas A & M University College Station TX 77843 USA Bert S. Turner department of Construction Management Louisiana State University Baton Rogue LA 70803 USA College of Engineering and Computing Nova Southeastern University Davie FL 33314 USA

This paper contributes an inclusive review of scientific studies in the field of sustainable human building ecosystems （SHBEs）. Reducing energy consumption by making buildings more energy efficient has been touted as an easily attainable approach to promoting carbon-neutral energy societies. Yet, despite significant progress in research and technology development, for new buildings, as energy codes are getting more stringent, more and more technologies, e.g., LED lighting, VRF systems, smart plugs, occupancy-based controls, are used. Nevertheless, the adoption of energy efficient measures in buildings is still limited in the larger context of the developing countries and middle income/low-income population. The objective of Sustainable Human Building Ecosystem Research Coordination Network （SHBE-RCN） is to expand synergistic investigative podium in order to subdue barriers in engineering, architectural design, social and economic perspectives that hinder wider application, adoption and subsequent performance of sustainable building solutions by recognizing the essential role of human behaviors within building-scale ecosystems. Expected long-term outcomes of SHBE-RCN are collaborative ideas for transformative technologies, designs and methods of adoption for future design, construction and operation of sustainable buildings.

关键词： sustainability building energy modeling(BEM) occupant behaviors (OB) sustainable ecosystems System for the Observation of Populous Heterogeneous Information (SOPHI)

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Ligation or Occlusion of the Internal Iliac Arteries for the Treatment of Placenta Accreta Spectrum:Why Is This Technique Still Performed?

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Maternal-Fetal Medicine 2023年第3期5卷 131-136页

作者： Albaro José Nieto-Calvache José M.Palacios-Jaraquemada Rozi Aditya Aryananda Nicolas Basanta Juan Manuel Burgos-Luna Fernando Rodriguez Carlos Ordonez Daniela Sarria-Ortiz laura Munoz-Cordoba Juan Carlos Quintero Valentina Galindo-Velasco Adriana Messa-Bryon Fundación Valle del Lili Departamento de Ginecología y ObstetriciaClínica de Espectro de Acretismo PlacentarioCali 760032Colombia latin American Group for the Study of Placenta Accreta Spectrum departamento de Ginecología y Obstetricia Hospital Universitario CEMICBuenos Aires C1431FWOArgentina department of Obstetrics and Gynecology Dr.Soetomo Academic General HospitalUniversitas AirlanggaSurabaya 60131Indonesia departamento de Ginecología y Obstetricia Hospital General de Agudos Juan A FernándezBuenos Aires 7011Argentina Fundación Valle del Lili Centro de Investigaciones ClínicasCali 760032Colombia Unidad de diagnóstico prenatal Clínica ImbanacoGrupo Quirón SaludCali 760042Colombia departamento de ginecología y obstetricia Universidad del ValleCali 760042Colombia Universidad Icesi Facultad de Ciencias de la SaludCali 760031Colombia

Introduction The major complication of placenta accreta spectrum(PAS)disorder is massive bleeding;therefore,multiple vascular interventions have been described to prevent or treat pelvic *** of the internal iliac arteries(IIAs)was published more than 130 years ago,and although research relating to the physiology of this procedure has demonstrated poor vascular control over the last few decades,2-this technique has evolved into an established technique known as endovascular IIA balloon occlusion.

关键词： balloon Internal bleeding

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Proposed nomenclature for Pseudallescheria,Scedosporium and related genera

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Fungal Diversity 2014年第4期67卷 1-10页

作者： Michaela lackner G.Sybren de Hoog Liyue Yang Leandro Ferreira Moreno Sarah A.Ahmed Fritz Andreas Josef Kaltseis Markus Nagl Cornelia lass-Florl Brigitte Risslegger Gunter Rambach Cornelia Speth Vincent Robert Walter Buzina Sharon Chen Jean-Philippe Bouchara Jose F.Cano-Lira Josep Guarro Josepa Gené Fabiola Fernández Silva rosa Haido Gerhard Haase Vladimir Havlicek dea Garcia-Hermoso Jacques F.Meis Ferry Hagen Martin Kirchmair Johannes Rainer Katharina Schwabenbauer Mirjam Zoderer Wieland Meyer Felix Gilgado Vania A.Vicente Elena Piecková Monika Regenermel Peter-Michael Rath Joerg Steinmann Xisto Wellington de Alencar Francoise Symoens Kathrin Tintelnot Krzysztof Ulfig Aristea Velegraki Anna Maria Tortorano Sandrine Giraud Sara Mina Kinga Rigler-Hohenwarter Fernando L.Hernando Andoni Ramirez-Garcia Aize Pellon Jashanpreet Kaur Eliana Barreto Bergter Jardel Vieira de Meirelles Ingrid Dutra da Silva laurence delhaes Ana Alastruey-Izquerdo Ruo-yu Li Qiaoyun Lu Tarek Moussa Omar Almaghrabi Hassan Al-Zahrani Gen Okada Shuwen deng Wangqing Liao Jingsi Zeng Jouni Issakainen Livia Cristina Liporagi Lopes Division of Hygiene and Medical Microbiology Innsbruck Medical UniversityInnsbruckAustria CBS Fungal Biodiversity Centre UtrechtThe Netherlands Institute for Biodiversity and Ecosystem Dynamics University of AmsterdamAmsterdamThe Netherlands Sun Yat-Sen Memorial Hospital Sun Yat-Sen UniversityGuangzhouChina Medical University of Graz GrazAustria Centre for Infectious Diseases and Microbiology Westmead HospitalWestmeadAustralia laboratoire de Parasitologie-Mycologie Centre Hospitalier UniversitaireAngersFrance Unitats de Microbiologia i d’Anatomia Patològica Facultat de Medicina i Ciències de la Salut IISPVUniversitat Rovira i VirgiliReusSpain Universidade Federal do Estado do Rio de Janeiro Rio de JaneiroBrazil Institute of Medical Microbiology University Hospital RWTHAachenGermany Institute of Microbiology Academy of SciencesPragueCzech Republic Institut Pasteur Unitéde Mycologie MoléculaireCentre National de Référence Mycoses Invasives et AntifongiquesParisFrance department of Medical Microbiology and Infectious Diseases Canisius-Wilhelmina HospitalNijmegenThe Netherlands department of Medical Microbiology RadboudumcNijmegenThe Netherlands Institute of Microbiology eopold-Franzens-University InnsbruckInnsbruckAustria Molecular Mycology Research laboratory Centre for Infectious Diseases and MicrobiologySydneyMedical School—Westmead HospitalMarie Bashir Institute for Infectious Diseases and BiosecurityThe University of SydneyWestmead Millennium InstituteWestmeadNSWAustralia Basic Pathology department Federal University of ParanáStateCuritibaParanáBrazil Fellowship from Conselho Nacional de desenvolvimento Científico e Tecnológico(CNPq) BrasíliaBrazil Institute of Preventive and Clinical Medicine BratislavaSlovakia Institut für Hygiene und Mikrobiologie landesklinikum St.Pölten St.PöltenAustria Institute of Medical Microbiology University Hospital EssenEssenGermany Nursing School of Unigranrio Rio de JaneiroBrazil Scientific Institute of Public Health Culture Collectio

As a result of fundamental changes in the International Code of Nomenclature on the use of separate names for sexual and asexual stages of fungi,generic names of many groups should be *** of the ECMM/ISHAM working group on Pseudallescheria/Scedosporium infections herein advocate a novel nomenclature for genera and species in Pseudallescheria,Scedosporium and allied *** generic names Parascedosporium,Lomentospora,Petriella,Petriellopsis,and Scedosporium are proposed for a lineage within Microascaceae with mostly Scedosporium anamorphs producing slimy,annellidic *** that Scedosporium has priority over Pseudallescheria and that Scedosporium prolificans is phylogenetically distinct from the other Scedosporium species,some name changes are *** minutispora and Petriellidium desertorum are renamed as Scedosporium minutisporum and ***,*** prolificans is renamed as Lomentospora prolificans.

关键词： Graphium Lomentospora Petriella Scedosporium apiospermum complex Microascaceae Nomenclature

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Quito Municipal Schools—Cohort Study: Self-Perception of Body Image and Factors Related with It

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Open Journal of Epidemiology 2014年第3期4卷 122-128页

作者： Natalia Romero-Sandoval Oscar Flores Carmen Egas Gabriela Villamar Zuleica larrea Manuel Cruz laura Icaza Miguel Martín Postgrado de Medicina Familiar y Comunitaria Facultad de Ciencias Médicas Universidad Central del Ecuador Quito Ecuador Unidad Metropolita.a.de Salud Centro Municipio del Distrito Metropolitano de Quito Quito Ecuador Universidad Internacional del Ecuador Facultad de Ciencias Médicas de la Salud y la Vida Escuela de Medicina Quito Ecuador

Self-perception of body image is one factor to be considered when planning and performing preventive initiatives and interventions in childhood and adolescence. The aim of this study was to analyse self-perception of body image in relation to body-mass index, physical inactivity, not eating breakfast, dieting, smoking and alcohol consumption or toxic habits. Materials and Methods: using data from the “Quito municipal schools” cohort study 6964 students aged from 9 to 17 years were described using a multivariate log linear model of the multidimensional table generated by the variables. A logistic regression model was then fitted to assess associations via OR. Results: 8.2% perceived themselves as overweight. Of those subjects overweight according to their BMI, 21.8% perceived themselves as such, while among those not overweight according to BMI, 96.8% considered themselves as slim or of normal weight. Among students who were dieting, 15.1% perceived themselves as overweight. Among those pupils who perceived themselves has having excess weight, the most common reasons for dieting were: lose weight (56.8%), be healthier (22.6%), and maintain current weight (8.4%). Self-perception of excess weight interacts with excess weight (ORadjusted 8.42;CI95% 6.92-10.25), no breakfast (ORadjusted 2.83;CI95% 2.13-3.77), diet (ORadjusted 2.38;CI95% 1.95-2.89), and with all the variables except toxic habits (ORadjusted 1.01;CI95% 0.78 a 1.29). Conclusion: Interventions to prevent obesity in childhood and adolescence ought to take account of specific determinants within the personal, behavioural and socio-environmental factors, such as the promotion of a positive body image.

关键词： Body Image Self-Perception Overweight and Obesity School Children Ecuador

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