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Analysis of the Risks of development Injury Related to Surgical Positioning in a University Hospital of the State of Goiás/Brazil: An Observational-Epidemiological Study

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Health 2020年第7期12卷 876-890页

作者： Bárbara Almeida Lemes Barbara correia Neves Sabino carlos Eduardo carvalho Sabino Ana clara Lenza Martins Ana Letícia Neller Finta André Vinícius de Oliveira Mariana cordeiro carvalho carolina Veras Mendes Giulia Ugucioni Garbelini lara cândida de sousa machado Idiberto José Zotarelli Filho Rio Verde University—UniRv Rio Verde Goiás Brazil Faculty of Medical Sciences State University of Campinas—UNICAMP Campinas Brazil Southwest Emergency Hospital—HURSO Brazil Faceres Medical School of Sã o José do Rio Preto/SP Brazil

Introduction: The perioperative nurse plays an important role throughout the surgical period, especially in the context of predicting the risks to which patients are exposed when entering a surgical center. These can be skin, muscle, tendon, and even burn injuries from the scalpel or chemicals. Objective: The aim of this study was to verify the degree of risk for the development of injuries resulting from surgical positioning in patients of a university hospital. Methods: This is cross-sectional, exploratory research with a quantitative approach conducted with 70 surgical patients in a Municipal University Hospital with data collection through a socioeconomic and health questionnaire and the Risk Assessment Scale for development of Surgical Positioning Injuries (SISP). Statistical analyses included simple descriptive evaluation, correlations of variables using the chi-square test and Pearson’s coefficient with a significance level of 5%. Results: The results found pointed to a population mainly composed of women (60%), married, with an average age of 49 years, with hypertension and high-risk scores to develop injuries due to surgical positioning. There was also a positive and significant correlation between having hypertension and having a higher risk of developing lesions, with R2 = 96.4% and p conclusion: The results reinforce the need to implement protocols and the acquisition of materials aimed at reducing the risk of injuries related to surgical positioning in order to improve the quality of care offered and thus minimize the harm to users.

关键词： Nursing Pressure Injury Operating Room

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contribution of mechanical forces to structural synaptic plasticity:insights from 3D cellular motility mechanisms

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Neural Regeneration Research 2025年第7期20卷 1995-1996页

作者： Rita O.Teodoro Mafalda Ribeiro Ramos lara carvalho iNOVA4Health NOVA Medical School|Faculdade de Ciências MédicasNMS|FCMUniversidade Nova de LisboaLisboaPortugal

cells,tissues,and organs are constantly subjected to the action of mechanical forces from the extracellular environment-and the nervous system is no ***-intrinsic properties such as membrane lipid composition,abundance of mechanosensors,and cytoskeletal dynamics make cells more or less likely to sense these *** and extrinsic cues are integrated by cells and this combined information determines the rate and dynamics of membrane protrusion growth or retraction(Yamada and Sixt,2019).cell protrusions are extensions of the plasma membrane that play crucial roles in diverse contexts such as cell migration and neuronal synapse *** the nervous system,neurons are highly dynamic cells that can change the size and number of their pre-and postsynaptic elements(called synaptic boutons and dendritic spines,respectively),in response to changes in the levels of synaptic activity through a process called *** plasticity is a hallmark of the nervous system and is present throughout our lives,being required for functions like memory formation or the learning of new motor skills(Minegishi et al.,2023;Pillai and Franze,2024).

关键词： plasticity structural mechanisms

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Reassessing the AMPK-MTORc1 balance in autophagy in the central nervous system

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Neural Regeneration Research 2025年第11期20卷 3209-3210页

作者： Marta García-Juan Mario Villa Irene Benito-cuesta lara Ordónez-Gutiérrez Francisco Wandosell centro de Biología Molecular“Severo Ochoa”(cSIc-UAM) Nicolas Cabrera 1Universidad Autónoma de MadridMadridSpain Fisiología Animal Departamento de BiologíaFacultad de CienciasUniversidad Autónoma de MadridMadridSpain department of clinical Neuroscience CMM Karolinska Universitetssjukhuset SolnaStockholmSweden departamento de Bioquímica y Biología Molecular Universidad Complutense de MadridMadridSpain centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas(cIBERNED) MadridSpain

Autophagy is a cellular degradation and recycling system,indispensable for cellular and organ development,homeostasis,and *** cellular process is evolutionarily highly conserved to quality control of many proteins and dysfunctional organelles,which finally recycle components as amino *** process is effective during normal physiology as part of anabolism and plays an additional important role during starvation(Dikic and Elazar,2018).Different types of autophagy have been chara cterized based on their dynamic,mechanism of action,target substrates,and protein *** of them are macroautophagy(hereafter called"autophagy"),microa utophagy,and chape rone-media ted autophagy(Fleming et al.,2022).

关键词： homeostasis system hereafter

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Anxiety Disorder in Adolescent and the Importance of Primary Health care to Identify This Illness

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Journal of Health Science 2018年第5期6卷 384-389页

作者： Daniel Ferreira Moraes de sousa Julia de Lima cabra Mylena Varela Santos Oliveira lara candida de sousa machado The department of Medicine University of Rio Verde (UniRV) 75900 Brazil Medical School University of Rio Verde (UniRV) 75900 Brazil

Summary： Introduction： Adolescence, is a life stage characterized by constant emotional instability and psychological conflicts. Analyzing the age of psychological transition of these adolescents along with the environment demands that those ones live, in conclusion, there are conflicts between particularities of intern and extern environment, besides self-knowledge of these adolescents, ending up in what we call AD （anxiety disorder）. Objective： Raise reader’s awareness about the early recognition of ADs and stress. Methodology： Based on literature review. The virtual library Scielo and the Latin American Journal of Nursing were mainly consulted. Results： The AD is characterized as a mental health disturbance, which has as main symptoms feelings of preoccupation, anxiety or fear which are strong enough to interfere in daily activities. Its detection should be as early as possible, therefore, primary health care is the most efficient to prevent and detect this illness. conclusion： It is possible to assure that primary health care （periodical medical check） has great impact on detecting and preventing the anxiety disorder in adolescent, since mental health professionals have used many working instruments which are useful for detecting this illness.

关键词： Anxiety primary health care depression

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Using the endocannabinoid system as a neuroprotective strategy in perinatal hypoxic-ischemic brain injury

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Neural Regeneration Research 2013年第8期8卷 731-744页

作者： lara-celador I. Goi-de-cerio F. Antonia Alvarez Enrique Hilario department of cell Biology and Histology School of Medicine and DentistryUniversity of the Basque Country GAIKER Technology centre Bizkaia Science and Technology Park

One of the most important causes of brain injury in the neonatal period is a perinatal hypoxicischemic *** devastating condition can lead to long-term neurological deficits or even *** hypoxic-ischemic brain injury,a variety of specific cellular mechanisms are set in motion,triggering cell damage and finally producing cell *** therapeutic treatments against this phenomenon are still unavailable because of complex molecular mechanisms underlying hypoxic-ischemic brain *** a thorough understanding of the mechanism underlying neural plasticity following hypoxic-ischemic brain injury,various neuroprotective therapies have been developed for alleviating brain injury and improving long-term *** them,the endocannabinoid system emerges as a natural system of *** endocannabinoid system modulates a wide range of physiological processes in mammals and has demonstrated neuroprotective effects in different paradigms of acute brain injury,acting as a natural *** aim of this review is to study the use of different therapies to induce long-term therapeutic effects after hypoxic-ischemic brain injury,and analyze the important role of the endocannabinoid system as a new neuroprotective strategy against perinatal hypoxic-ischemic brain injury.

关键词： neural regeneration reviews perinatal hypoxia-ischemia brain injury brain plasticity,neuroprotective strategies cannabinoid system grants-supported paper photographs-containingpaper neuroregeneration

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carbon dioxide fixation into cyclic carbonates at room temperature catalyzed by heteroscorpionate aluminum complexes

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Green chemical Engineering 2022年第3期3卷 280-287页

作者： Felipe de la cruz-Martinez Jose A.castro-Osma Agustin lara-Sanchez Universidad de castilla-La Mancha Departamento de Quimica InorganicaOrganica y Bioquimica-Centro de Innovacion en Quimica Avanzada(ORFEO-CINQA)Facultad de Ciencias y Tecnologias QuimicasCiudad Real13071Spain Instituto de Investigaciones Quimicas(IIQ) Departamento de Quimica Inorganica and Centro de Innovacion en Quimica Avanzada(ORFEO-CINQA)Consejo Superior de Investigaciones Cientificas(CSIC)and University of SevillaSevilla41092Spain Universidad de castilla-La Mancha Departamento de Quimica InorganicaOrganica y Bioquimica-Centro de Innovacion en Quimica Avanzada(ORFEO-CINQA)Facultad de FarmaciaAlbacete02071Spain

Novel mono-and bimetallic scorpionate aluminum compounds have been designed and characterized by spec-troscopic *** organometallics complexes,in combination with tetrabutylammonium bromide as cocatalyst,displayed good catalytic activity for the cycloaddition of styrene oxide and cO_(2) under ambient *** the compounds tested,monometallic complex 3 featuring diethylamino groups showed the highest catalytic *** catalytic system catalyzed the formation of cyclic carbonate products from their corresponding epoxides at room temperature and 1 bar of cO_(2) pressure in the absence of a solvent in good yields and excellent selectivities.

关键词： cO_(2) Epoxides cyclic carbonates Aluminum complexes

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Profitability of RE-Technology Regarding the Economic Environment:A case Study of Swiss SMEs

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Journal of Electronic Science and Technology 2018年第4期16卷 351-366页

作者： lara Thalmann Yves Hertig international institute of management in technology University of Fribourg Fribourg 1700Switzerland

considering the important changes in the Swiss energy sector, especially in renewable energy(RE)technologies, new revenue possibilities for small and medium sized enterprises(SMEs) emerge. However, the adaption of RE-technologies for Swiss enterprises relies on tangible financial returns, based on complex calculations. This article analyses business opportunities(BOs) of eight Swiss SMEs considering the net present value of RE-investments in an uncertain economic environment. We identify two profitable BOs for Swiss SMEs and three which are not profitable. Further, the article demonstrates that the profitability of such investments remains mostly positive even under economic uncertainties. Surprisingly the profitability does not change significantly if the SME receives a subsidy or not. The support instrument of the Swiss Government has not a ponderous impact on the decision to invest in RE-technologies or not. Therefore, the article emphasizes the importance of including SME in the Swiss attempt to decentralize the energy market.

关键词： Net present value renewable energy(RE)-investments sensitivity analysis small and medium sized enterprises(SMEs)

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Pigmented well-differentiated hepatocellular neoplasm with β-catenin mutation

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Hepatobiliary & Pancreatic Diseases International 2015年第6期14卷 660-664页

作者： lara Neves Souza Rodrigo Bronze de Martino Richard Thompson Sandra Strautnieks Nigel D Heaton Alberto Quaglia Institute of Liver Studies King's College Hospital department of Gastroenterology Discipline of Liver and Gastrointestinal TransplantationHospital das ClínicasUniversity of S?o Paulo

ABSTRAcT： According to the most recent WHO classification of hepatocellular adenomas, a small percentage of inflammatory hepatocellular adenomas presents with mutation in the β-catenin gene and are at higher risk of malignant transformation. It has been recognized that adenoma-like hepatocellular neoplasms with focal atypia, or in unusual clinical context present with similar cytogenetic and immunohistochemistry characteristics to well-differentiated hepatocellular carcino- mas.

关键词： hepatocellular adenoma hepatocellular carcinoma β-catenin glutamine synthetase diethylstilbestrol

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The “PAWPER-on-a-page”: Increasing global access to a low-cost weight estimation system

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World Journal of Emergency Medicine 2019年第2期10卷 101-108页

作者： Mike Wells lara Nicole Goldstein Division of Emergency Medicine Faculty of Health Sciences University of the Witwatersrand

BAcKGROUND: The PAWPER tape is one of the most accurate weight estimation systems available today, but international access to the tape is limited because it has no commercial distribution. For this reason, the "PAWPER-on-a-page" concept was devised: downloadable image fi les that allow users to print and assemble their own tapes. However, the feasibility of this method is dependent on users being able to produce accurate tapes. This study was devised to determine whether untrained participants could print and assemble the "PAWPER-on-a-page" easily and ***: Doctor and nurse volunteers downloaded the "PAWPER-on-a-page" and "PAWPER XL-on-a-page" image files and printed copies on a home-printer and also at a commercial printer. One copy of each tape was then assembled according to instructions from an online video. The accuracy of printing and assembly, the time taken for assembly and the cost were then ***: There were 32 participants. The median time for assembly was 8 minutes 19 seconds and 7 minutes 31 seconds for the "PAWPER-on-a-page" and "PAWPER XL-on-a-page" respectively, with a median cost of USD 0.09 and USD 1.00 respectively. For the assembled tapes, 71.9% of the "PAWPER-on-a-page" tapes and 65.6% of the "PAWPER XL-on-a-page" achieved the required accuracy of 0.2%. Printing errors, related to scaling, were common, but easily ***: The "PAWPER-on-a-page" system can be easily, quickly, affordably and accurately printed and assembled by end users. Stringent double checking of the printed and fully assembled tapes is essential to ensure accuracy.

关键词： PAWPER tape Weight estimation Paediatric emergency care

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Use of improved cold-finger technique to assess effects of basicity on heat transfer through solidified mold flux

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Journal of Iron and Steel Research International 2019年第4期26卷 393-402页

作者： Karina lara Santos Assis Petrus christiaan Pistorius department of Materials Science and Engineering Center for Iron and Steelmaking ResearchCarnegie Mellon UniversityPittsburgh 15213PAUSA

cold-finger measurements were used to estimate the contact resistance and average thermal conductivity of mold flux films solidified on a water-cooled copper *** industrial mold fluxes,with basicities from low to high,were *** steady-state rate of convective heat transfer between the solid film and liquid flux was compared with calculations based on natural convection correlations;the comparison indicates that the surface of the solid film(in contact with molten flux)is approximately at its solidus *** roughness of the mold flux film in contact with copper was larger for films grown from higher-temperature mold flux and for higher-basicity mold *** glassy(low-basicity)film had an estimated thermal conductivity of 1.1 W/(m K).The crystalline or partially crystalline films had higher estimated thermal conductivities of 2.2-3.2 W/(m K).The measured values of thermal resistance were extrapolated to typical mold flux film thicknesses for industrial conditions;the extrapolations confirmed that the high contact resistance of higher-basicity mold fluxes can yield higher thermal resistances than the low-basicity *** morphology of the rough interface of higherbasicity mold flux films that gives the higher contact resistance is consistent with that observed in previous work and appears not to be directly related to crystallization.

关键词： Mold flux Heat transfer conduction contact resistance-cold-finger technique

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