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Visible Light Indoor Positioning System Based on Pisarenko Harmonic Decomposition and Neural Network

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Chinese Journal of Electronics 2024年第1期33卷 195-203页

作者： Li ZHAO Yi REN Qi WANG lange DENG Feng ZHANG School of Electronic Information Engineering Xi’an Technological University

Visible-light indoor positioning is a new generation of positioning technology that can be integrated into smart lighting and optical communications. The current received signal strength(RSS)-based visible-light positioning systems struggle to overcome the interferences of background and indoor-reflected noise. Meanwhile, when ensuring the lighting, it is impossible to use the superposition of each light source to accurately distinguish light source information; furthermore, it is difficult to achieve accurate positioning in complex indoor environments. This study proposes an indoor positioning method based on a combination of power spectral density detection and a neural network. The system integrates the mechanism for visible-light radiation detection with RSS theory, to build a back propagation neural network model fitting for multiple reflection channels. Different frequency signals are loaded to different light sources at the beacon end, and the characteristic frequency and power vectors are obtained at the location end using the Pisarenko harmonic decomposition method. Then, a complete fingerprint database is established to train the neural network model and conduct location tests. Finally, the location effectiveness of the proposed algorithm is verified via actual positioning experiments. The simulation results show that, when four groups of sinusoidal waves with different frequencies are superimposed with white noise, the maximum frequency error is 0.104 Hz and the maximum power error is 0.0362 W. For the measured positioning stage, a 0.8 m × 0.8 m × 0.8 m solid wood stereoscopic positioning model is constructed, and the average error is 4.28 cm. This study provides an effective method for separating multi-source signal energies, overcoming background noise, and improving indoor visible-light positioning accuracies.

关键词： Neural networks Measurement uncertainty Position measurement Harmonic analysis Light emitting diodes Frequency estimation Indoor positioning systems

Characterization of microstructure evolution of cement paste by micro computed tomography

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Journal of Central South University 2013年第4期20卷 1115-1121页

作者：何永佳 Jason Mote David A. lange State Key Laboratory of Silicate Materials for Architectures (Wuhan University of Technology) School of Materials Science and Engineering Wuhan University of Technology Department of Civil and Environmental Engineering University of Illinois at Urbana-Champaign

Micro computed tomography (Micro-CT) was applied to obtain three-dimensional images of the microstructure of cement paste (water-to-cement mass ratio of 0.5) at different ages. By using the Amira software, component phases of the cement paste such as pores, hydration products, and unhydrated clinker particles were segmented from each other based on their 3D image grey levels; their relative contents were also calculated with the software, and the data are 61.2%, 0% and 38.8% at the beginning of hydration and 11.8%, 78.5% and 9.7% at 28 d age, respectively. The hydration degree of cement paste at different ages was compared with the experimental data acquired by loss on ignition (LOI) tests. The results show that the calculated and measured data reasonably agree with each other, which indicates that micro-CT is a useful and reliable approach to characterize the micro structure evolution of hydrating cement paste.

关键词： Micro computed tomography (Micro-CT) 3D image microstructure cement paste

Coronavirus disease 2019 (COVID-19) and global mental health

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Global Health Journal 2021年第1期5卷 31-36页

作者： Klaus W.lange Institute of Psychology University of RegensburgRegensburgBavaria 93040Germany

The mental health effects of the coronavirus disease 2019(COVID-19)pandemic may shape population health for many years to *** to address the mental health issues stemming from the pandemic is likely to prolong its *** COVID-19 pandemic has created a significant global challenge and,in lower-income countries,even a disruption of mental health *** our experience with previous pandemics,the present COVID-19 crisis can be expected to cause psychological trauma,and steps are needed to address this issue *** focusing on the long-term mental health consequences of COVID-19 may equal the importance of those currently seeking to mitigate its physical *** implications of the GOVID-19 pandemic for mental health call for a greater focus on the needs of those with mental disorders and on mental health issues affecting health care workers and the general *** preventive and therapeutic mental health care is essential in addressing the psychosocial needs of populations exposed to the *** addition to specialist care,"task-shifting"and digital technologies may provide cost-effective means of providing mental health care in lower-income countries worldwide as well as in higher-income countries with mental health services overwhelmed by the effects of the COVID-19 *** view of the ever-increasing pressure on global health systems resulting from the COVID-19 pandemic,adopting and adapting"task-shifting",i.e.,the delegation of psychotherapeutic interventions to trained non-specialists,as an element of the provision of mental health services,is *** technologies can be used to enhance social support and facilitate resilience to the detrimental mental health effects of the pandemic;they may also offer an efficient and cost-effective way to provide easy access to mentalhealth care.

关键词： Coronavirus disease 2019(COVID-19) Mental health Prevention Treatment Task shifting Digital technology

Task sharing in psychotherapy as a viable global mental health approach in resource-poor countries and also in high-resource settings

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Global Health Journal 2021年第3期5卷 120-127页

作者： Klaus W.lange Institute of Psychology Urtiversiiy of RegensburgRegensburgBavaria 93040Germany

A global disparity exists between the burden of mental ill-health and the resources available to address this *** mental disorders,such as mild-to-moderate depression,anxiety disorders and post-traumatic stress disorder,are associated with a significant decline in health and functioning and contribute significantly to the overall burden of *** view of a shortage of mental health professionals in most low-and middle-income countries,task sharing(task shifting)can make an important contribution to improving access to mental health *** sharing involves non-specialists in the delivery of health *** use of lay health workers is premised on the assumption that the shorter training required for non professionals will allow an increase in the provision of required care without the need for an increase in resources and will strengthen and scale-up sustainable health *** need for low-tech support in the management of conunon mental disorders is widespread,and the core resource is humans trained to identify and treat those requiring mental health *** is a strong evidence base for the effectiveness of task sharing in psychotherapy,and talk therapies,*** behavioral therapy,can easily be delegated to non-specialists,including non-specialist health workers,peer helpers and lay people.A(cost-)effective model of mental health care in low-resource settings as well as in high-income countries may include the medical school-based training of some psychiatrists and clinical psychologists in the treatment of referred patients with serious mental *** professional mental health specialists would also be trainers and supervisors of non-specialist health workers who would identify common mental health disorders and provide psychotherapy to people with these conditions in a community-based ***-based generalism including task sharing rather than centralized specialism may be capable of preventing and treating many

关键词： Mental health care Poor-resource settings Task sharing Psychotherapy Cognitive behavioral therapy

Omega-3 fatty acids and mental health

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Global Health Journal 2020年第1期4卷 18-30页

作者： Klaus W.lange Institute of Psychology University of Regensburg93040 RegensburgGermany

Nutrition plays a key role in brain development,mental health,and psychiatric *** role of omega-3 polyunsaturated fatty acids in physical health is well established,and their role in mental health is becoming increasingly ***-3 fatty acids are involved in a wide range of physiological functions that are related to neurogenesis,neurotransmission,and neuroinflammation;therefore,they play fundamental roles in the development,functioning,and aging of the *** humans,dietary deficiencies of omega-3 fatty acids are associated with an increased risk of developing various psychiatric disorders,including depression,bipolar disorder,schizophrenia,dementia,attention-deficit/hyperactivity disorder,and *** particular,eicosapentaenoic and docosahexaenoic acid have been linked to the maintenance of mental health,and their deficits have been implicated in the pathophysiology of mental *** may be mediated by the modulation of inflammatory processes and their direct effects on neuronal membrane fluidity and receptor ***,randomized clinical trials that have investigated the therapeutic effects of omega-3 fatty acids have yielded inconclusive results,thereby limiting the use of these nutrients in psychiatric ***-quality clinical trials should be conducted to examine the efficacy of omega-3 fatty acids in preventing and treating mental *** undesirable side effects of omega-3 fatty acid supplementation should also be *** effects may become apparent after many years of administration,and therefore,they may not be detected in most cases.

关键词： Omega-3 fatty acids Mental health Neurodevelopmental disorders Dementia Depression Schizophrenia

Medical foods in Alzheimer’s disease

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Food Science and Human Wellness 2019年第1期8卷 1-7页

作者： Klaus W.lange Jianjun Guo Shigehiko Kanaya Katharina M.lange Yukiko Nakamura Shiming Li Department of Experimental Psychology University of Regensburg93040 RegensburgGermany China Institute of Sport Science BeijingChina Graduate School of Information Science Nara Institute of Science and TechnologyIkomaJapan Department of Psychology University of WinchesterWinchesterUnited Kingdom Department of Food Science Rutgers UniversityNew BrunswickNJUSA

Alzheimer’s disease(AD)is the most prevalent cause of dementia *** achieving a marked improvement in symptoms or preventing or delaying the progression of the disease are not *** diet-related risk factors for AD have been *** for a protective effect of the Mediterranean diet on AD risk is *** foods are designed to meet specific dietary needs for certain *** in symptomatology and regional brain atrophy in AD have been claimed for several medical foods,for example,those providing ketone bodies as alternative energy supply to neurons,those containing precursors believed to improve synaptic function,and those addressing oxidative stress related to memory *** methodological shortcomings render the interpretation of the available findings of medical food trials in AD *** results of medical foods in AD may be expected when administered in presymptomatic or early stages of the *** requires the reliable identification of minimal neuropathological changes related to *** outcome measures currently used may not be able to detect subtle changes in cognition and function in early ***-scale clinical studies using valid,sensitive,and reliable assessment tools are needed to establish the efficacy of medical foods in AD.

关键词： Alzheimer’s disease Ketogenic diet Medical foods Mediterranean diet Nutrition

Methodology to develop machine learning algorithms to improve performance in gastrointestinal endoscopy

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World Journal of Gastroenterology 2018年第45期24卷 5057-5062页

作者： Thomas de lange Pal Halvorsen Michael Riegler Department of Transplantation Oslo University HospitalOslo 0424Norway Institute of Clinical Medicine University of OsloOslo 0316Norway Center for Digital Engineering Simula Metropolitan Fornebu 1364Norway

Assisted diagnosis using artificial intelligence has been a holy grail in medical research for many years, and recent developments in computer hardware have enabled the narrower area of machine learning to equip clinicians with potentially useful tools for computer assisted diagnosis(CAD) systems. However, training and assessing a computer's ability to diagnose like a human are complex tasks, and successful outcomes depend on various factors. We have focused our work on gastrointestinal(GI) endoscopy because it is a cornerstone for diagnosis and treatment of diseases of the GI tract. About 2.8 million luminal GI(esophageal, stomach, colorectal) cancers are detected globally every year, and although substantial technical improvements in endoscopes have been made over the last 10-15 years, a major limitation of endoscopic examinations remains operator variation. This translates into a substantial inter-observer variation in the detection and assessment of mucosal lesions, causing among other things an average polyp miss-rate of 20% in the colon and thus the subsequent development of a number of post-colonoscopy colorectal cancers. CAD systems might eliminate this variation and lead to more accurate diagnoses. In this editorial, we point out some of the current challenges in the development of efficient computer-based digital assistants. We give examples of proposed tools using various techniques, identify current challenges, and give suggestions for the development and assessment of future CAD systems.

关键词： Endoscopy Artificial intelligence Deep learning Computer assisted diagnosis Gastrointestinal

Highly Fuel-Efficient Transmission and Propulsion Concepts

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Automotive Innovation 2018年第1期1卷 35-42页

作者： Ferit Küçükay Andreas lange Lin Li Institute of Automotive Engineering(IAE) Technische Universität Braunschweig38106 BraunschweigGermany

The integration of one or more electricmachines into the drivetrain has resulted inmany different powertrain concepts in recent years,ranging from the P2 hybrid to dedicated hybrid transmission(DHT).Two types of DHT with different characteristics are *** first type is the power split hybrid(PS-DHT),which has very low mechanical complexity but needs high electrical effort in the *** second type is multi-mode DHT(MM-DHT),which has a slightly higher mechanical complexity but much less electrical effort when compared with the PS-DHT.A transmission synthesis is used to determine the concept of the *** three different powertrain concepts(i.e.,P2,PS-DHT,and MM-DHT)are analyzed and evaluated regarding fuel economy and *** driving cycles(e.g.,Worldwide Harmonized Light vehicles Test Procedure)and the 3D method(driver,driven vehicle,driving environs)are used to investigate the drivetrain in the context of real driving *** show that the two DHT concepts offer better fuel economy than the P2 hybrid drivetrain while still providing the same or even better driving *** study also shows that new hybrid concepts created with transmission synthesis can lead to further improvements in hybrid powertrains.

关键词： Dedicated hybridtransmission Three-dimensional method Drivetraindesign Fuel economy Drivingperformance

Prime time for base editing in the mitochondria

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Signal Transduction and Targeted Therapy 2022年第8期7卷 2630-2631页

作者： Michael A.Morgan Lucas lange Axel Schambach Institute of Experimental Hematology Hannover Medical SchoolHannover 30625Germany REBIRTH Research Center for Translational Regenerative Medicine Hannover Medical SchoolHannover 30625Germany Division of Hematology/Oncology Boston Children’s HospitalHarvard Medical SchoolBostonMA 02115USA

A recent study published in Cell by the Kim lab represents a great advance towards expanding DNA editing possibilities to mitochondrial DNA(mtDNA)as they show reasonable targeted A-to-G conversions in human mtDNA using base editors to broaden the arsenal of available tools.1 Mutations in mitochondrial DNA(mtDNA)are linked to several diseases(Fig.1),thus,development of gene therapy and editing approaches could lead to curative options for patients suffering from these *** this direction,gene editing tools such as zinc-finger nucleases(mitoZFN),transcription activator-like effector nucleases(mitoTALENs)and meganucleases(mitoARCUS)were shown to eliminate mutant mtDNA and shift heteroplasmy.

关键词： diseases base curative