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Omega-3 fatty acids and mental health

作     者:Klaus W.Lange Klaus W. Lange

作者机构:Institute of PsychologyUniversity of Regensburg93040 RegensburgGermany 

出 版 物:《Global Health Journal》 (全球健康杂志(英文))

年 卷 期:2020年第4卷第1期

页      面:18-30页

学科分类:1002[医学-临床医学] 10[医学] 

主  题:Omega-3 fatty acids Mental health Neurodevelopmental disorders Dementia Depression Schizophrenia 

摘      要:Nutrition plays a key role in brain development,mental health,and psychiatric *** role of omega-3 polyunsaturated fatty acids in physical health is well established,and their role in mental health is becoming increasingly ***-3 fatty acids are involved in a wide range of physiological functions that are related to neurogenesis,neurotransmission,and neuroinflammation;therefore,they play fundamental roles in the development,functioning,and aging of the *** humans,dietary deficiencies of omega-3 fatty acids are associated with an increased risk of developing various psychiatric disorders,including depression,bipolar disorder,schizophrenia,dementia,attention-deficit/hyperactivity disorder,and *** particular,eicosapentaenoic and docosahexaenoic acid have been linked to the maintenance of mental health,and their deficits have been implicated in the pathophysiology of mental *** may be mediated by the modulation of inflammatory processes and their direct effects on neuronal membrane fluidity and receptor ***,randomized clinical trials that have investigated the therapeutic effects of omega-3 fatty acids have yielded inconclusive results,thereby limiting the use of these nutrients in psychiatric ***-quality clinical trials should be conducted to examine the efficacy of omega-3 fatty acids in preventing and treating mental *** undesirable side effects of omega-3 fatty acid supplementation should also be *** effects may become apparent after many years of administration,and therefore,they may not be detected in most cases.

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