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基于四邻域对角线上灰度约束的亚像素角点检测

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计算机工程与设计 2019年第1期40卷 77-83页

作者：骆荣坤刘桂礼孔全存李东北京信息科技大学仪器科学与光电工程学院北京100192 北京信息科技大学现代测控技术教育部重点实验室北京100192

针对微棋盘格亚像素角点检测过程中,存在漏检、多检及检测精度较低等问题,在研究现有算法的基础上,提出一种基于四邻域对角线上灰度约束的角点检测方法。通过角点的四邻域中心几何特征及其对角线方向上最大灰度特征的分析,采用SINC函数... 详细信息

针对微棋盘格亚像素角点检测过程中,存在漏检、多检及检测精度较低等问题,在研究现有算法的基础上,提出一种基于四邻域对角线上灰度约束的角点检测方法。通过角点的四邻域中心几何特征及其对角线方向上最大灰度特征的分析,采用SINC函数灰度分布约束角点位置,实现亚像素级精度的角点检测。开展对比实验及误差分析,其结果表明,与现有检测方法相比,该方法的多检率降低了约18%,漏检率降低了约2.,均达0;其检测精度提高了约50%,达到0.3Pix。该方法显著提高了亚像素角点检测的准确率、精度和重复率,在显微标定中具有一定的应用价值。

关键词：角点检测棋盘格四邻域对角线灰度约束亚像素精度显微标定

100 TeV diffuse γ-rays observation by YangBaJing Hybrid Array

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Radiation Detection technology and Methods 2020年第3期4卷 392-398页

作者： Jian-Cheng He Yu-Hua Yao Zhen Wang Tian-Lu Chen Dan-Zeng-luo-Bu Cun-Feng Feng Youliang Feng Qi Gao Yi-Qin Guo Ying-Ying Guo Hong-Bo Hu Xing-Tao Huang Cheng Liu Mao-Yuan Liu Yi-Bin Pan Bing-Qiang Qiao Guang-Guang Xin Xue-Yao Zhang Yi Zhang Shi-Ping Zhao key laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of Sciences(CAS)Beijing 100049China university of Chinese Academy of sciences(UCAS) Beijing 100049China College of Physics Sichuan UniversityChengdu 610064China Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghai 200240China Physics Department of science School Tibet UniversityLhasa 850000China Institute of Frontier and Interdisciplinary science Shandong UniversityJinan 250100China key laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of Sciences(CAS)Nanjing 210008China Department of Physics University of Wisconsin-Madison1150 University ave MadisonMadisonWI 53706USA School of Physics and technology Wuhan UniversityWuhan 430072China

Purpose Cosmic rays up to PeV energy are believed to be generated in our galaxy.γ-rays at 100TeV energies are important probe to identify ***,γ-rays contain additional information on the propagation of the galactic cosmic *** Diffuseγ-rays originating from the Galactic plane from 2. to 2.0 TeV region are studied with early 160-day data collected by YangBaJing Hybrid Array(YBJ-HA),which is a hybrid array and consists of scintillation detectors and underground muon ***-distance equi-zenith angle and time-swapping methods are used to analyze the number ofγ-rays *** and conclusion Because of no significant observation onγ-ray emission,Helene's method is adopted to derive the 90%confidence level upper limits on the flux of diffuse galacticγ-*** the limit to the ratio of the flux ofγ-rays to CRs is obtained at the order of 10^(-4),which is the current best result at these energies.

关键词： Cosmic rays Diffuse y-rays YBJ-HA EAS

Simulation study of BESⅢwith stitched CMOS pixel detector using AcTs

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Nuclear science and Techniques 2023年第12期34卷 264-270页

作者： Yi Liu Xiao‑Cong Ai Guang‑Yan Xiao Ya‑Xuan Li Ling‑Hui Wu Liang‑Liang Wang Jia‑Ning Dong Ming‑Yi Dong Qing‑Lin Geng Min luo Yan Niu An‑Qing Wang Chen‑Xu Wang Meng Wang Lei Zhang Liang Zhang Rui‑Kai Zhang Yao Zhang Ming‑Gang Zhao Yang Zhou School of Physics and Microelectronics Zhengzhou UniversityZhengzhou 450001China School of Physics Nanjing UniversityNanjing 210093China School of Physics Nankai UniversityTianjin 300071China Institute of High Energy Physics Chinese Academy of Sciences19B Yuquan RoadShijingshan DistrictBeijing 100049China Research Center for Particle science and technology Institute of Frontier and Interdisciplinary ScienceShandong UniversityQingdao 266237China university of Chinese Academy of sciences 19A Yuquan RoadShijingshan DistrictBeijing 100049China School of information science and Engineering Harbin Institute of TechnologyWeihai 264209China

The reconstruction of the tracks of charged particles with high precision is crucial for HEP experiments to achieve their physics *** BESⅢdrift chamber,which is used as the tracking detector of the BESⅢexperiment,has suffered from aging effects resulting in degraded tracking performance after operation for approximately 15 *** preserve and enhance the tracking performance of BESⅢ,one of the proposals is to add one layer of a thin cylindrical CMOS pixel sensor based on state-of-the-art stitching technology between the beam pipe and the drift *** improvement in the tracking performance of BESⅢwith such an additional pixel detector compared to that with only the existing drift chamber was studied using the modern common tracking software Acts,which provides a set of detector-agnostic and highly performant tracking algorithms that have demonstrated promising performance for a few high-energy physics and nuclear physics experiments.

关键词： BESⅢtracking detector CMOS pixel sensor Track reconstruction Common tracking software

CD4^(+)NKG2.^(+)T细胞在幼年特发性关节炎疾病活动中的作用

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中国当代儿科杂志 2023年第2期25卷 166-171页

作者：王君言朱晓萍张宇罗冲唐雪梅周娟重庆医科大学附属儿童医院风湿免疫科/国家儿童健康与疾病临床医学研究中心/儿童发育重大疾病国家国际科技合作基地/儿童感染免疫重庆市重点实验室/儿童发育疾病研究教育部重点实验室重庆400014 贵州医科大学附属医院贵州省儿童医学中心贵州贵阳550004

目的分析幼年特发性关节炎(juvenile idiopathic arthritis,JIA)活动期及稳定期CD4^(+)NKG2.^(+)T细胞及NKG2.可溶性配体,即可溶性MHC-Ⅰ类链相关分子A和B(soluble MHC classⅠchain-related molecules A/B,sMICA/sMICB)表达水平,探讨其在JIA疾病活动中的作用。方法前瞻性纳入2.19年11月—2.2.年12.重庆医科大学附属儿童医院确诊的全身型JIA 19例和关节型JIA 2.例,6例健康儿童为对照组。收集外周血标本,采用酶联免疫吸附法测定sMICA和sMICB水平,采用流式细胞术检测CD4^(+)NKG2.^(+)T细胞比例,采用全身型幼年关节炎疾病活动评分-2.(systemic Juvenile Arthritis Disease Activity Score,sJADAS-2.)/幼年关节炎疾病活动评分-2.(Juvenile Arthritis Disease Activity Score-2.,JADAS-2.)评估JIA患儿的疾病活动性。采用Pearson相关分析法、受试者工作特征曲线分析CD4^(+)NKG2.^(+)T细胞及sMICA、sMICB在JIA疾病活动中的作用。结果全身型JIA活动期组及关节型JIA活动期组CD4^(+)NKG2.^(+)T细胞比例较对照组及各自稳定期组升高(P2.^(+)T细胞比例及sMICA、sMICB水平与sJADAS-2./JADAS-2.评分呈正相关(P2.^(+)T细胞比例及sMICA、sMICB水平较健康儿童升高,且与疾病活动性呈正相关,提示CD4^(+)NKG2.^(+)T细胞及NKG2.配体可作为JIA疾病活动性评估的新指标。

关键词：幼年特发性关节炎自然杀伤细胞活化性受体2. 疾病活动性儿童

公平与效率导向下农村公共医疗资源的空间优化研究——以湖北省仙桃市为例

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地理科学 2019年第9期39卷 1455-1463页

作者：田玲玲张晋王法辉李响郑文升罗静华中师范大学地理过程分析与模拟湖北省重点实验室/城市与环境科学学院湖北武汉430079 湖北省发展和改革委员会/华中师范大学武汉城市圈研究院湖北武汉430079 美国路易斯安那州立大学地理与人类学系美国路易斯安那70803 华东师范大学地理信息科学教育部重点实验室上海200062

公共服务资源的空间配置问题一直存在效率与公平价值导向的博弈,空间综合人文社科的兴起,使其演化成一个空间优化问题。医疗资源空间配置的规划注重决策连续性,据此提出改进空间可达性的两步优化法。在农村地区资源有限的情况下,以空间... 详细信息

公共服务资源的空间配置问题一直存在效率与公平价值导向的博弈,空间综合人文社科的兴起,使其演化成一个空间优化问题。医疗资源空间配置的规划注重决策连续性,据此提出改进空间可达性的两步优化法。在农村地区资源有限的情况下,以空间可达性为主要指标,建立公平与效率导向下的二次规划模型,通过重新选址和设定规模以保证居民获得就医机会的最大公平和效率,并以湖北省仙桃市为案例进行应用研究。结果表明,新选地址和规模优化结果能使仙桃市医疗资源空间配置的公平性和效率性得到显著提高,2.步骤相结合,使其成为真正的混合优化模型,达到效率和公平平衡的双重目标。

关键词：农村公共医疗资源公平与效率两步优化湖北仙桃

Type-Augmented Link Prediction Based on Bayesian Formula

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国际计算机前沿大会会议论文集 2023年第2期 304-317页

作者： Ye Wang Enze luo Lijie Li Wenjian Tao College of Computer science and technology Harbin Engineering UniversityHarbinChina Purification Equipment Research Institute of CSIC HandanChina

Knowledge graphs(KGs)play a pivotal role in various real-world applications,but they are frequently plagued by incomplete information,which manifests in the form of missing *** prediction,which aims to infer missing entities given existing facts,has been mostly addressed by maximizing the likelihood of observed triplets at the instance ***,they ignore the semantic information most KGs contain and the prior knowledge implied by the semantic *** address this limitation,we propose a Type-Augmented Link Prediction(TALP)approach,which builds a hierarchical feature model,computes type feature weights,trains them to be speciﬁc to different relations,encodes weights into prior probabilities and convolutional encodes instance-level information into likelihood probabilities;ﬁnally,combining them via Bayes rule to compute the posterior probabilities of entity *** proposed TALP approach achieves signiﬁcantly better performance than existing methods on link prediction benchmark datasets.

关键词： Knowledge Graph Link Prediction Bayes Formula Type information

过敏性紫癜患儿血清高迁移率族蛋白B1表达及意义

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中国实用儿科杂志 2021年第7期36卷 503-507页

作者：阮小霞罗冲安云飞唐雪梅张宇重庆医科大学附属儿童医院风湿免疫科儿童发育疾病研究教育部重点实验室国家儿童健康与疾病临床医学研究中心(重庆)儿童发育重大疾病国家国际科技合作基地儿童感染免疫重庆市重点实验室重庆400014

目的测定过敏性紫癜(HSP)患儿血清高迁移率族蛋白B1(HMGB1)水平,分析血清HMGB1与实验室指标的相关性,初步探讨HMGB1与HSP发病及肾损害的关系。方法纳入2.17年12.至2.19年12.在重庆医科大学附属儿童医院初诊为HSP患儿83例,其中45例无... 详细信息

目的测定过敏性紫癜(HSP)患儿血清高迁移率族蛋白B1(HMGB1)水平,分析血清HMGB1与实验室指标的相关性,初步探讨HMGB1与HSP发病及肾损害的关系。方法纳入2.17年12.至2.19年12.在重庆医科大学附属儿童医院初诊为HSP患儿83例,其中45例无肾脏受累(A组)、38例合并肾脏损害(B组),恢复期HSP患儿18例(C组),健康对照组2.例(D组),采用酶联免疫吸附法测定患儿血清HMGB1水平。比较A组、B组、C组、D组之间以及不同肾脏受累程度患儿血清HMGB1水平,分析血清HMGB1与实验室指标的相关性。结果 (1)A组、B组、C组、D组患儿的血清HMGB1水平分别为:10.71(6.81~16.03)μg/L、13.77(10.02.2..72.μg/L、7.58(5.73~10.83)μg/L、4.96(3.97~5.43)μg/L,A组与B组、C组、D组之间的差异均有统计学意义(P2.急性期孤立性血尿型(12.)、孤立性蛋白尿型(13例)、血尿和蛋白尿型(13例)患儿血清HMGB1水平分别为:10.98(8.07~16.38)μg/L、12.81(8.45~2..89)μg/L、17.39(13.02.2..79)μg/L,3组之间的差异无统计学意义(P>0.05)。(3)HSP患儿血清HMGB1水平与白细胞计数、中性粒细胞百分比、血清IgA浓度、D-二聚体水平、2. h尿蛋白定量之间呈线性正相关,与淋巴细胞百分比呈线性负相关(P<0.05)。结论血清HMGB1表达与HSP肾脏损害有关,HMGB1可能参与HSP急性炎症。

关键词：过敏性紫癜紫癜性肾炎高迁移率族蛋白B1 儿童

InAs基范德华异质结界面电荷转移特性第一性原理计算的研究进展

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红外与毫米波学报 2023年第5期42卷 666-680页

作者：成田恬张坤罗曼孟雨欣祖源泽王奕锦王鹏余晨辉南通大学信息科学技术学院江苏省专用集成电路设计重点实验室江苏南通226019 中国科学院上海技术物理研究所红外物理国家重点实验室上海200083

由低维InAs材料和其他二维层状材料堆叠而成的垂直范德华异质结构在纳米电子、光电子和量子信息等新兴领域中应用广泛。探索跨结界面的电荷转移机制对于全面理解该类器件的非凡特性至关重要。第一性原理计算在揭示界面电荷转移特性与各... 详细信息

由低维InAs材料和其他二维层状材料堆叠而成的垂直范德华异质结构在纳米电子、光电子和量子信息等新兴领域中应用广泛。探索跨结界面的电荷转移机制对于全面理解该类器件的非凡特性至关重要。第一性原理计算在揭示界面电荷转移特性与各种能量稳定型InAs基范德华异质结的电、光、磁等原理物理特性和器件性能变化之间的内在关系方面发挥着不可比拟的作用。文中梳理、总结和探讨了近年来InAs基范德华异质结间界面电荷转移特性的理论研究工作与潜在的功能应用,提出在理论方法和计算精度方面大力发展第一性原理计算的几个途径,为更好地开展InAs基范德华异质结的基础科学研究和应用器件设计提供可借鉴的量化研究基础。

关键词： InAs异质结范德华堆叠结构界面电荷转移第一性原理计算

A novel lytic phage potentially effective for phage therapy against Burkholderia pseudomallei in the tropics

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Infectious Diseases of Poverty 2022年第4期11卷 98-98页

作者： Yanshuang Wang Xuemiao Li David A.B.Dance Han Xia Chen Chen Nini luo Anyang Li Yanmei Li Qiao Zhu Qinghui Sun Xingyong Wu Yingfei Zeng Lin Chen Shen Tian Qianfeng Xia key laboratory of Tropical Translational Medicine of {2. of education NHC Key Laboratory of Tropical Disease ControlSchool of Tropical Medicine and The Second Affliated HospitalHainan Medical UniversityHaikouHainanChina 不详

Background:Burkholderia pseudomallei is a tropical pathogen that causes *** intrinsic drug-resistance is a leading cause of treatment failure,and the few available antibiotics require prolonged use to be *** study aimed to assess the clinical potential of *** phages isolated from Hainan,***:Burkholderia pseudomallei strain(HNBPoo1)was used as the isolation host,and phages were recovered from domestic environmental sources,which were submitted to the host range determination,lytic property assays,and stability *** best candidate was examined via the transmission electron microscope for *** its genome sequenced and analyzed,its protective efficacy against *** infection in A549 cells and Caenorhabditis elegans was evaluated,in which cell viability and survival rates were compared using the one-way ANOVA method and the log-rank ***:A phage able to lyse 2./2. clinical isolates was *** was classified in the Podoviridae family and was found to be amenable to *** the optimal multiplicity of infection(MOl)of o.1,an eclipse period of around 2. min and a high titer(io12.PFU/ml)produced within 1 h were *** phage was found stabile at a wide range of temperatures(2.,37,40,50,and 60 C)and pH values(3-12..After being designated as vB_BpP_HN01,it was fully sequenced,and the 71,398 bp linear genome,containing 93 open reading frames and a tRNA-Asn,displayed a low sequence similarity with known ***,protective effects of applications of vB_BpP_HNo1(MOl=0.1 and MOl=1)alone or in combination with antibiotics were found to improve viability of infected cells(70.6±6.8%,85.8±5.7%,91.9±1.8%,and 96.8±1.8%,respectively).A significantly reduced mortality(10%)and a decreased pathogen load were demonstrated in infected *** following the addition of this ***:As the frst *** phage was isolated in Hainan,china,phage vB_BpP_HNO1 was

关键词： classification. protective stability