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Brain region-specific roles of brain-derived neurotrophic factor in social stress-induced depressive-like behavior

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Neural Regeneration Research 2025年第1期20卷 159-173页

作者： Man Han Deyang Zeng Wei Tan Xingxing Chen Shuyuan Bai Qiong Wu Yushan Chen zhen Wei Yufei mei Yan Zeng Brain Science and Advanced Technology Institute Wuhan University of Science and TechnologyWuhanHubei ProvinceChina Geriatric Hospital Affiliated to Wuhan University of Science and Technology WuhanHubei ProvinceChina School of Public Health Wuhan University of Science and TechnologyWuhanHubei ProvinceChina

Brain-derived neurotrophic factor is a key factor in stress adaptation and avoidance of a social stress behavioral *** studies have shown that brain-derived neurotrophic factor expression in stressed mice is brain region–specific,particularly involving the corticolimbic system,including the ventral tegmental area,nucleus accumbens,prefrontal cortex,amygdala,and *** how brain-derived neurotrophic factor participates in stress processing in different brain regions will deepen our understanding of social stress *** this review,we discuss the expression and regulation of brain-derived neurotrophic factor in stress-sensitive brain regions closely related to the pathophysiology of *** focused on associated molecular pathways and neural circuits,with special attention to the brain-derived neurotrophic factor–tropomyosin receptor kinase B signaling pathway and the ventral tegmental area–nucleus accumbens dopamine *** determined that stress-induced alterations in brain-derived neurotrophic factor levels are likely related to the nature,severity,and duration of stress,especially in the above-mentioned brain regions of the corticolimbic ***,BDNF might be a biological indicator regulating stress-related processes in various brain regions.

关键词： amygdala chronic mild stress chronic social defeat stress corticolimbic system depression hippocampus medial prefrontal cortex nucleus accumbens social stress models ventral tegmental area

Structure and Mechanical Properties of Al-based Gradient Composites Reinforced with Primary Si and Mg_2Si Particles through Centrifugal Casting

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Journal of Wuhan University of Technology(Materials Science) 2013年第4期28卷 813-818页

作者：翟彦博 MA Xiuteng mei zhen College of Engineering and Technology Southwest University Congqing Machine Tool (Group) Co. Ltd.

The structure and mechanical properties of a new type of Al-based discontinuous gradient composites prepared by using the ternary AI-19Si-5Mg alloys as the raw material adopting the centrifugal casting method were investigated. Structurally, the composites are divided into two zones： a reinforced zone with the high volume fraction of primary Si and Mg2Si particles and an unreinforced zone with no or a few particles. In the reinforced zone, the primary particles are evenly distributed, with the sizes of the primary Si particles 80-120 μm, and that of primary Mg2Si particles 20-50 μm. The properties test results show the reinforced zone has higher Rockwell hardness and better wear resistance than the unreinforced zone, due to the complementary reinforcement relationship between the primary Si and Mg2Si particles and their high volume fraction.

关键词： gradient composites centrifugal casting primary Si primary Mg2Si

Effect of CF and RPP on the Mechanical and Electrical Properties of Smart Aggregate

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Journal of Wuhan University of Technology(Materials Science) 2018年第2期33卷 437-444页

作者：王海峰 mei zhen College of Civil Engineering Huaqiao University

By using redispersible polymer powder（RPP） and carbon fiber（CF） to adjust the flexibility and electrical properties of the smart aggregate, a new kind of smart aggregate with Z type structure was proposed. The study shows that Z type aggregate is more sensitive to the feedback of external force than the prism aggregate in the same loading environment, and it indicates that Z type aggregate is more suitable for the research and application of concrete health monitoring. Although the incorporation of RPP would cause the compressive strength of the aggregates and the elastic modulus of hardened cement mortar to reduce slightly within the dosage of RPP by 2.25% because of the polymer film formed in the internal system, this would improve the deformability of the aggregates. In the early loading stage（in the first 60 seconds）, the intelligent concrete specimens implanted with Z type smart aggregate do not show higher sensitivity as expected, although the resistance change rate changes a little bit more, the overall of it is still in balance. Adding RPP could improve the flexibility of smart aggregates exactly, and it plays an active role in prolonging the life of the smart aggregates. By implanting Z type aggregates the damage and failure of the concrete structure could be predicted accurately in this study. The results of this paper will help to promote further research and application of intelligent concrete.

关键词： carbon fiber(CF) redispersible polymer powder(RPP) mechanical and electrical properties smart aggregate intelligent concrete

Basic Physical Characteristics of the Water-permeable Brick with Composite Structure

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Journal of Wuhan University of Technology(Materials Science) 2022年第4期37卷 645-655页

作者： WANG Haifeng LIU Yang mei zhen College of Civil Engineering Huaqiao UniversityXiamen 361021China Higher-educational Engineering Research Centre for Intelligence and Automation in Construction of Fujian Province College of Civil EngineeringHuaqiao UniversityXiamen 361021China

The resin-sand mixture was proposed to be used as the surface course,and cement permeable concrete was used as the base course;such two kinds of materials were combined to prepare water-permeable brick with a composite *** compressive strength,flexural strength,and permeability were studied by using adjusting the contents of carbon fiber,quartz powder,cement,sand,and *** study shows that the hydrophilicity of the resin-sand mixture can be improved after any amount of resin is replaced by quartz powder;by using the surfactant,the interface energy of the particles can be reduced so that the water permeability of the surface course can be promoted ***,the mechanical properties of the surface course were negatively affected by the *** the optimal process consideration in the experiments,the properties about compressive strength,flexural strength,and permeability of the composite permeable brick can meet the requirements of the specifications of resin-sand based water permeable brick JGT 376-2012(compressive strength was higher than 35 MPa,the flexural strength exceeded 5.19 MPa,and the average permeability coefficient was higher than 2.3×10^(-2)cm/s).There are no obvious pores on the surface course and only water molecules can pass through it,therefore,the surface of the permeable brick cannot be blocked up by solid substances,and the permeability of such permeable brick can be improved effectively in this way.

关键词： water-permeable brick resin composite structure permeability surfactant

Effect of HPMC on the Piezoresistivity of Smart Concrete Aggregate with Z Shape

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Journal of Wuhan University of Technology(Materials Science) 2020年第4期35卷 768-777页

作者： WANG Haifeng YAN Handong mei zhen College of Civil Engineering Huaqiao UniversityXiamen 361021China

Cement mortar with carbon fiber(CFc)and resin-cement mortar with carbon fiber(CFrc)were used as inner and outer cores of smart aggregate with Z shape,respectively,which was used as the basic perception units to prepare smart concrete aggregate with a mosaic structure(SAMS).The hydroxpropyl methylcellulose(HPMC)was taken into consideration to improve the properties of mortar;by using HPMC,the structure of SAMS was optimized and its mechanical and electrical properties were *** experimental results show that the toughness of mortar could be improved by the complex that formed by epoxy resin,and the effect of HPMC on the flexibility of CFc was greater than that on the flexibility of CFrc;the feasible designing indicates that the CFc-Z core and CFrc-Z core could be used as inner and outer cores of *** the proposed dosages of HPMC in inner and outer cores are 0.35wt%and 0.2wt%,respectively,it could give an effective prediction for the damage of concrete during the loading process.

关键词： smart aggregate hydroxpropyl methylcellulose(HPMC) smart concrete piezoresistivity

Sub-nanometer structured silicon-carbon composite nanolayers armoring on graphite for fast-charging and high-energy-density lithium-ion batteries

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Rare Metals 2023年第11期42卷 3692-3704页

作者： zhen-Wei Li mei-Sheng Han Jie Yu Songshan Lake Materials Laboratory Dongguan523808China Guangdong Provincial Key Laboratory of Semiconductor Optoelectronic Materials and Intelligent Photonic Systems Shenzhen Engineering Lab for Supercapacitor MaterialsSchool of Material Science and EngineeringHarbin Institute of TechnologyShenzhenShenzhen 518055China Department of Mechanical and Energy Engineering Southern University of Science and TechnologyShenzhen518055China

Silicon/carbon composites are promising alternatives to current graphite anodes in commercial lithiumion batteries(LIBs)because of their high capacity and excellent ***,the unsatisfactory fastcharging capability and cycle stability of Si/C composites caused by slow charge transport capability and huge volume change under industrial electrode conditions severely hamper their ***,a novel Si/C anode was fabricated by homogeneously depositing amorphous C-Si nanolayers on graphite(C-Si@graphite).C-Si nanolayers with uniformly dispersed sub-nanometer Si particles in 3D carbon skeleton significantly boost electron and Li-ion transport and efficiently relieve Si's agglomeration and volume *** a result,the tailored C-Si@graphite electrodes show an excellent rate capacity(760.3 mAh·g^(-1)at 5.0C)and long cycle life of over 1000 cycles at 1.0C and800 cycles at 2.0C under industrial electrode *** addition,the assembled full cells(C-Si@graphite,anode;Li[Ni_(0.8)Co_(0.1)Mn_(0.1)]O_(2),cathode)present superior fastcharging capability(240.4 Wh·kg^(-1),charging for16.2 min,3.0C)and long cycle life(80.7%capacity retention after 500 cycles at 1.0C),demonstrating the massive potential of C-Si@graphite for practical application.

关键词： Si/C anode Sub-nanometer Si Fast-charging capability Lithium-ion batteries(LIBs)

Optical coatings for fiber lasers

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光学精密工程 2005年第4期13卷 480-482页

作者： HONG Dong-mei ZHU zhen YUE Wei North China Research Institute of Electro-optics BeiJing 100015 China

Fiber laser is the future development direction for the high energy lasers. This paper describs two kinds of optical coatings for fiber laser, including long and short wave pass filters. The one characteristic of fiber laser coatings lies in that coatings should separate two closely wavelength light including laser pump wavelength (980 nm) and laser irradiation wavelength(1 050～1 100 nm). At the same time, the coatings should have high laser damage threshold.

关键词：光纤激光器光学涂覆技术结构设计波长

Monitoring impact of mefenacet treatment on soil microbial communities by PCR-DGGE fingerprinting and conventional testing procedures

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Journal of Environmental Sciences 2006年第2期18卷 373-378页

作者： YE Yang-fang MIN Hang LU zhen-mei College of Life Science and Biotechnology Ningbo University Ningbo 315211 China College of Life Science Zhejiang University Hangzhou 310029 China

The effect of acetanilide herbicide mefenacet on soil microbial communities was studied using paddy soil samples with different short-term treatments. The culturable bacteria （plate counts）, dehydrogenase activity and changes in community structure （denaturing gradient gel electrophoresis （DGGE） analysis） were used for biological community assessments. Mefenacet was a significant stimulus to cultural aerobic bacteria and dehydrogenase activity while Sphingobacterium multivorum Y1, a bacterium efficiently degrading the mefenacet, only induced the increasing colony-forming unit （CFU） of bacteria but little effect on dehydrogenase activity during the whole experiment. The degree of similarity between the 16S rDNA profiles of the communities was quantified by numerically analyzing the DGGE band patterns. Similarity dendrograms showed that the microbial community structures of the mefenacet-treated and non-treated soils were not significantly different. But supplement of S. multivorum Y1 could increase the diversity of the microbial community in the mefenacet-polluted paddy soil. This work is a new attempt to apply the S. multivorum Y1 for remediation of the mefenacet-polluted environments.

关键词： denaturing gradient gel electrophoresis(DGGE) soil microbial diversity mefenacet dehydrogenase

Progress and prospects of noncoding RNAs in insects

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Journal of Integrative Agriculture 2019年第4期18卷 729-747页

作者： LI mei-zhen XIAO Hua-mei HE Kang LI Fei Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects Institute of Insect Sciences College of Agriculture and Biotechnology Zhejiang University College of Life Sciences and Resource Environment Yichun University

With the rapid development of high-throughput sequencing technology and bioinformatics algorithms, great progress has been made in the field of noncoding RNA(ncRNA) in the last decade. RNA molecules have been regarded only as a messenger between DNA and protein for decades, but now they have new roles in the biological process as ncRNAs. A growing number of ncRNAs have been identified in insects from the RNA-Seq data of small RNA libraries or transcriptomes. ncRNAs have varied regulatory functions at the epigenetic, transcriptional, or post-transcriptional levels, and participate in almost all types of biological processes. Here, we review the research progress of four kinds of ncRNAs, including microRNA(miRNA), Piwiinteracting RNA(piRNA), circular RNA(circRNA), and long noncoding RNA(lncRNA) in insects. The discovery, biogenesis mechanisms, and regulatory functions of these ncRNAs are presented here to provide a comprehensive understanding of insect ncRNAs and to promote the application of ncRNAs in insect pest control.

关键词： miRNA piRNA circRNA lncRNA biogenesis prediction regulatory functions