Progress and prospects of noncoding RNAs in insects

作     者：LI Mei-zhen XIAO Hua-mei HE Kang LI Fei 

作者机构：Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects Institute of Insect Sciences College of Agriculture and Biotechnology Zhejiang University College of Life Sciences and Resource Environment Yichun University 

出 版 物：《Journal of Integrative Agriculture》 (农业科学学报（英文版）)

年 卷 期：2019年第18卷第4期

页      面：729-747页

核心收录：

学科分类：09[农学] 

基　　金：supported by the National Key Research and Development Program(2017YFD0200900,2017YFD0200904,2017YFC1200602 and 2016YFC1200600) the National Natural Science Foundation of China(31772238,31760514 and 31701785) 

主　　题：miRNA piRNA circRNA lncRNA biogenesis prediction regulatory functions 

摘      要：With the rapid development of high-throughput sequencing technology and bioinformatics algorithms, great progress has been made in the field of noncoding RNA(ncRNA) in the last decade. RNA molecules have been regarded only as a messenger between DNA and protein for decades, but now they have new roles in the biological process as ncRNAs. A growing number of ncRNAs have been identified in insects from the RNA-Seq data of small RNA libraries or transcriptomes. ncRNAs have varied regulatory functions at the epigenetic, transcriptional, or post-transcriptional levels, and participate in almost all types of biological processes. Here, we review the research progress of four kinds of ncRNAs, including microRNA(miRNA), Piwiinteracting RNA(piRNA), circular RNA(circRNA), and long noncoding RNA(lncRNA) in insects. The discovery, biogenesis mechanisms, and regulatory functions of these ncRNAs are presented here to provide a comprehensive understanding of insect ncRNAs and to promote the application of ncRNAs in insect pest control.