检索结果-南通市图书馆

Gelatin-Based Metamaterial Hydrogel Films with High Conformality for Ultra-Soft Tissue Monitoring

Nano-Micro Letters 2024年第2期16卷 347-364页

作者： Yuewei Chen Yanyan Zhou Zihe Hu weiying lu Zhuang Li Ning Gao Nian Liu Yuanrong Li Jing He Qing Gao Zhijian Xie Jiachun Li Yong He State Key Laboratory of Fluid Power and Mechatronic Systems School of Mechanical EngineeringZhejiang UniversityHangzhou 310027People’s Republic of China School of Mechanical Engineering Guizhou UniversityGuiyang 550025People’s Republic of China Stomatology Hospital School of StomatologyZhejiang University School of MedicineClinical Research Center for Oral Diseases of Zhejiang ProvinceKey Laboratory of Oral Biomedical Research of Zhejiang ProvinceCancer Center of Zhejiang UniversityHangzhou 310006People’s Republic of China

Implantable hydrogel-based bioelectronics(IHB)can precisely monitor human health and diagnose ***,achieving biodegradability,biocompatibility,and high conformality with soft tissues poses significant challenges for *** is the most suitable candidate for IHB since it is a collagen hydrolysate and a substantial part of the extracellular matrix found naturally in most *** study used 3D printing ultrafine fiber networks with metamaterial design to embed into ultra-low elastic modulus hydrogel to create a novel gelatin-based conductive film(GCF)with mechanical *** regulation of GCF nearly covers soft tissue mechanics,an elastic modulus from 20 to 420 kPa,and a Poisson’s ratio from-0.25 to *** negative Poisson’s ratio promotes conformality with soft tissues to improve the efficiency of biological *** GCF can monitor heartbeat signals and respiratory rate by determining cardiac deformation due to its high ***,the gelatin characteristics of the biodegradable GCF enable the sensor to monitor and support tissue *** GCF metamaterial design offers a unique idea for bioelectronics to develop implantable sensors that integrate monitoring and tissue repair and a customized method for endowing implanted sensors to be highly conformal with soft tissues.

关键词： Implantable hydrogel-based bioelectronics Conformality 3D printing Metamaterial design

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

妊娠期阴道微生态与妊娠结局相关性研究进展

引用

海南医学院学报 2024年第11期30卷 873-880页

作者：徐小惠马宁卢伟英海南省妇女儿童医学中心产科海南海口570312 海南省妇女儿童医学中心生殖中心海南海口570312 海南医学院附属儿童医院海南海口571199

健康的育龄女性阴道内存在的微生物种类繁多,其中乳酸杆菌为主要菌群,是维持阴道微生态平衡的重要角色。当阴道内的酸碱度失衡、菌群结构紊乱、局部免疫功能下降等情况发生时,阴道微生态平衡则容易被破坏,甚至发生阴道感染。阴道微生态... 详细信息

健康的育龄女性阴道内存在的微生物种类繁多,其中乳酸杆菌为主要菌群,是维持阴道微生态平衡的重要角色。当阴道内的酸碱度失衡、菌群结构紊乱、局部免疫功能下降等情况发生时,阴道微生态平衡则容易被破坏,甚至发生阴道感染。阴道微生态紊乱不仅影响女性生活质量,还与女性妊娠期的不良妊娠结局存在相关性,影响母婴健康。因此,本文就妊娠期阴道微生态情况及其与妊娠结局相关性研究进展做一综述。

关键词：妊娠期阴道微生态妊娠结局

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Novel structural designs of 3D-printed osteogenic graft for rapid angiogenesis

引用

生物设计与制造（英文） 2023年第1期6卷 51-73页

作者： weiying lu Yang Shi Zhijian Xie Stomatology Hospital School of StomatologyZhejiang University School of MedicineZhejiang UniversityHangzhou 310006China Key Laboratory of Oral Biomedical Research of Zhejiang Province Zhejiang UniversityHangzhou 310006China Cancer Center Zhejiang UniversityHangzhou 310006China Zhejiang Provincial Clinical Research Center for Oral Diseases Zhejiang UniversityHangzhou 310006China

Large bone defect regeneration has always been recognized as a challenging clinical problem due to the difficulty of *** treatments exhibit certain inherent disadvantages(e.g.,secondary injury,immunization,and potential infections).However,three-dimensional(3D)printing technology as an emerging field can serve as an effective approach to achieve satisfactory revascularization while making up for the above limitations.A wide variety of methods can be used to facilitate blood supply during the design of a 3D-printed ***,the scaffold structure lays a foundation for the entire printing object;any method to promote angiogenesis can be effective only if it is based on well-designed *** this review,different designs related to angiogenesis are summarized by collecting the literature from recent *** 3D-printed scaffolds are classified into four major categories and discussed in detail,from elementary porous scaffolds to the most advanced bone-like ***,structural design suggestions to achieve rapid angiogenesis are proposed by analyzing the above *** review can provide a reference for organizations or individual academics to achieve improved bone defect repair and regeneration using 3D printing.

关键词： 3D printing Angiogenesis Bone regeneration Tissue engineering Biomimetic scaffolds

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

菌群与早发性卵巢功能不全的研究进展

引用

中华生殖与避孕杂志 2024年第3期44卷 310-314页

作者：宋艳琴吴亚妹周知马宁万邦贝卢伟英海南省妇女儿童医学中心生殖医学中心海口570206

早发性卵巢功能不全(premature ovarian insufficiency,POI)是指在女性40岁之前卵巢功能衰退或丧失,导致女性不孕的常见原因,其发病机制复杂。近期微生物群与生殖内分泌疾病的研究成为了热点,本综述菌群通过免疫反应、炎症因子及代谢功... 详细信息

早发性卵巢功能不全(premature ovarian insufficiency,POI)是指在女性40岁之前卵巢功能衰退或丧失,导致女性不孕的常见原因,其发病机制复杂。近期微生物群与生殖内分泌疾病的研究成为了热点,本综述菌群通过免疫反应、炎症因子及代谢功能等途径参与POI的发生发展过程,同时通过服用益生菌、粪便微生物群移植等方式能够改善菌群失调,从而改善POI相关症状。未来有望通过菌群与POI机制的进一步研究,为POI的诊治提供新的策略。

关键词：早发性卵巢功能不全肠道菌群阴道微生态发病机制治疗

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A symmetric substructuring method for analyzing the natural frequencies of conical origami structures

引用

Theoretical & Applied Mechanics Letters 2024年第3期14卷 203-210页

作者： Chenhao lu Yao Chen weiying Fan Jian Feng Pooya Sareh Key Laboratory of Concrete and Prestressed Concrete Structures of Ministry of Education and National Prestress Engineering Research CenterSoutheast UniversityNanjing 211189China School of Engineering University of LiverpoolLiverpool L693BXUnited Kingdom Creative Design Engineering Lab(Cdel) School of EngineeringNewcastle UniversityNewcastle upon Tyne NE17RUUnited Kingdom Escuela Técnica Superior de Ingeniería y Diseño Industrial Universidad Politécnica de Madrid(UPM)Madrid 28012Spain

Conical origami structures are characterized by their substantial out-of-plane stiffness and *** investigations have commonly focused on the static characteristics of these lightweight ***,the efficient analysis of the natural vibrations of these structures is pivotal for designing conicalorigami structures with programmable stiffness and *** this paper,we propose a novel method to analyzethe natural vibrations of such structures by combining a symmetric substructuring method(SSM)and a gener-alized eigenvalue *** exploits the inherent symmetry of the structure to decompose it into a finiteset of repetitive *** doing so,we reduce the dimensions of matrices and improve computationalefficiency by adopting the stiffness and mass matrices of the substructures in the generalized eigenvalue *** element simulations of pin-jointed models are used to validate the computational results of the ***,the parametric analysis of the structures demonstrates the influences of the number of seg-ments along the circumference and the radius of the cone on the structural mass and natural frequencies of ***,we present a comparison between six-fold and four-fold conical origami structures anddiscuss the influence of various geometric parameters on their natural *** study provides a strategyfor efficiently analyzing the natural vibration of symmetric origami structures and has the potential to contributeto the efficient design and customization of origami metastructures with programmable stiffness.

关键词： Natural structural vibration Origami design Group theory Symmetric substructuring method(SSM) Generalized eigenvalue analysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Phase diagram of the CsBr-CaBr_2 system

引用

Rare Metals 2006年第3期25卷 293-296页

作者： BAO Xinhua CHEN Nianyi lu Wencong CHENG Zhixuan luO Yunyun lu weiying XIA Yiben School of Materials Science and Engineering Shanghai University Shanghai 200072 China School of Sciences Shanghai University Shanghai 200444 China

The phase diagram of the CsBr-CaBr2 system was re-determined by using differential thermal analysis and high ternperature and room ternperature X-ray diffraction analysis. It is concluded that there are three intermediate compounds in this system： *** melting compound, CsCaBr3, with a melting point of 823℃ and two incongruently melting compounds, Cs2CaBr4 and Cs3Ca2Br7, whose peritectic points being 597℃ and 635℃, respectively. X-ray diffraction analysis indicated that compound CsCaBr3 is of slightly distorted perovskite structure.

关键词： phase diagram CsBr-CaBr2 system differential thermal analysis (DTA) X-ray diffraction analysis perovskite structure

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

New Rural Community Construction or Retention Development:A Comparative Analysis of Rural Settlement Transition Mechanism in Plain Agriculture Area of China Based on Actor Network Theory

引用

Chinese Geographical Science 2024年第3期34卷 436-452页

作者： QU Yanbo DONG Xiaozhen MA Wenqiu ZHAO weiying School of Public Administration and Policy Shandong University of Finance and EconomicsJinan 250014China Institute of Land Science and Policy Shandong University of Finance and EconomicsJinan 250014China College of Engineering China Agricultural UniversityBeijing 100083China

It is an important way to realize rural revitalization and sustainable development to guide rural settlement transition(RST)in an appropriate *** paper uses actor network theory(ANT)to construct a theoretical framework for the study of *** two typical villages with different transition paths in rural areas of North China Plain as examples,this paper reveals the mechanism of RST and makes a comparative *** results show that:1)after identifying problems and obligatory passage point,key actors recruit heterogeneous actors into the actor network by entrusting them with common interests,and realize RST under the system operation.2)Rural settlements under different transition paths have similarities in the problems to be solved,collective actions and policy factors,but there are differences in the transition process,mechanism and *** actor network and mechanism of RST through the path of new rural community construction are more complex and the transition effect is more *** contrast,the degree of RST of retention development path is limited if there is no resource and location advantage.3)Based on the applicable conditions of different paths,this paper designs a logical framework of‘Situation-Structure-Behavior-Result’to scientifically guide the identification of RST paths under the background of rural revitalization.

关键词： rural settlement transition(RST) actor network theory(ANT) transition path transition mechanism plain area China

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Evaluating the tumor stratification with a lysosomal pH sensitive-probe by fluorescence lifetime imaging

引用

Chinese Chemical Letters 2024年第3期35卷 262-267页

作者： Jun Yan Xing Liang Qian Zhang luolin Wang weiying Lin Guangxi Key Laboratory of Electrochemical Energy Materials Institute of Optical Materials and Chemical BiologySchool of Chemistry and Chemical EngineeringGuangxi UniversityNanning 530004China

Owing to the anaerobic metabolism in the tumor,abundant acidic metabolites are produced and accumulated in the ***,the cells in different tumor layers are directly linked to the pH ***,due to the lack of robust tools,the high-efficient evaluation of the acidic micro-environment of tumor stratification faces the challenge of accurate *** designed a new pH sensitive fluorescent lifetime probe target to *** we expected,the fluorescence lifetime of PLN possesses a good linear fit to the pH value,which could detect the pH change at a single lysosome level in real time,and then evaluate the different acidity of tumor *** probe PLN is successfully used to evaluate the tumor stratification by fluorescence lifetime imaging microscopy(FLIM)for the first time,which is of great significance in the preoperative diagnosis of clinical tumor treatment or evaluation of drug delivery effect.

关键词： FLIM pH Fluorescence imaging Lysosome Tumor imaging

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Activatable photoacoustic bioprobe for visual detection of aging in vivo

引用

Chinese Chemical Letters 2024年第4期35卷 324-329页

作者： Zihong Li Jie Cheng Ping Huang Guoliang Wu weiying Lin Institute of Optical Materials and Chemical Biology Guangxi Key Laboratory of Electrochemical Energy MaterialsSchool of Chemistry and Chemical EngineeringGuangxi UniversityNanning 530004China

Aging is a natural physiological process with various challenges, related to the loss of homeostasis within the organism, which is not a disease, but a significantly strong risk factor for multiple diseases, including myocardial infarction, stroke, some age-related cancers, macular degeneration, osteoarthritis, neurodegeneration, and many others. In the body, the main manifestation of aging is cellular aging, which exists within tissues and has a local or global impact on tissue function. However, the lack of effective aging detection tools has always been an issue that cannot be ignored in the field of aging research. Therefore,it is necessary to construct a non-invasive tool for in vivo detection of aging. Here, we show that the photoacoustic probe(LGAL), which has peak excitation and emission wavelengths in the near-infrared optical window, binds in vivo and at high contrast to the hallmark of aging, and allows for the microscopic imaging of aging through the intact mice. Firstly, this tool LGAL has been successfully applied to detect senescence in cells, displaying stronger photoacoustic signals than normal cells. Then, by using the photoacoustic probe, the blood vessels and tissues inside the mice can be visualized. Young and elderly mice exhibit varying intensities of photoacoustic signals, marking the first time a probe has been used to explore the aging of blood vessels and tissues inside the mice. Finally, we monitored the changes in the degree of aging during tumor treatment under photoacoustic(PA) imaging for the first time. As the treatment time increased, the degree of aging of the tumor gradually deepened. We expect the powerful tool could be a noninvasive and powerful tool for the study of aging biology.

关键词： Near-infrared Photoacoustic Aging Senescence Tumor Sa-β-gal

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

我与《敦煌研究》牵手相伴四十载——为纪念敦煌研究院建院八十周年而作

引用

敦煌研究 2024年第4期 47-53页

作者：梁尉英敦煌研究院编辑部

回顾《敦煌研究》创刊以来40年的发展历程，作者与《敦煌研究》牵手相伴40年中的编辑工作的艰辛，并追忆了工作、旅途中的逸事。今日之《敦煌研究》已经是树立在社会科学期刊界的一面旗帜，更是敦煌学学术高地上的一面旗帜，引领着敦煌... 详细信息

回顾《敦煌研究》创刊以来40年的发展历程，作者与《敦煌研究》牵手相伴40年中的编辑工作的艰辛，并追忆了工作、旅途中的逸事。今日之《敦煌研究》已经是树立在社会科学期刊界的一面旗帜，更是敦煌学学术高地上的一面旗帜，引领着敦煌学向广度、深度研究发展的一面旗帜。

关键词：敦煌学《敦煌研究》创刊发展旗帜

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：