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NEW METHOD OF SIMULATING CONCENTRATED DRAIN HOLES IN SEEPAGE CONTROL ANALYSIS

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Journal of Hydrodynamics 1999年第3期11卷 27-35页

作者： Zhan Mei li, Su Bao yu , liu Jun yong, Shen zhen zhong College of Water Conservancy and Hydropower Engineering, Hohai University, Nanjing 210098, P.R.China (Received Aug.1, 1998)

In this paper, based upon the basic solution of sink, the approximate solution of single drain hole in finite elements is derived by use of the superposition principle. Then, the theoretical solution is extended to the case of some drain holes in one finite element, and the method is used in seepage control analysis with quick convergence and high accuracy. On the other hand, if the positions of the drain holes are changed, only some control factors of drain holes are changed, but the finite element grid need not to be reformed. Therefore, the method is more suitable in optimal research of seepage control.

关键词： concentrated drain hole approximate solution seepage control optimal research

Clinical Observation on Treatment of Colonic Cancer with Combined Treatment of Chemotherapy and Chinese Herbal Medicine

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Chinese Journal of Integrative Medicine 2009年第2期15卷 107-111页

作者：周留勇单珍珠尤建良 Department of Oncology Wuxi Municipal Hospital of Traditional Chinese Medicine

Objective:To observe the clinical effect of combined chemotherapy and Chinese herbal medicine in treating colonic ***:One hundred and sixty-three patients were assigned,according to their will,to two groups,105 in the traditional Chinese medicine treated group(Group A) and 58 in the combined treatment group(Group B).The Chinese herbal drug Zhao s Weitiao No.3(赵氏微调3号方,ZW3) was given to both groups,twice a day,40 mL each time,30 days as one cycle,and over 6 cycles applied in *** patients in G...

关键词： Chinese herbal medicine chemotherapy clinical observation

防风网对露天煤堆PM_(2.5)的减排效果评估方法

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煤炭学报 2016年第S2期41卷 576-582页

作者：段振亚刘永阵周驰焦煜张俊梅青岛科技大学机电工程学院山东青岛266061 清华大学国家环境保护大气复合污染来源与控制重点实验室北京100084 青岛科技大学化工学院山东青岛266042

科学评价防风网的减排效果,特别是其针对PM_(2.5)的减排率,对指导防风网优化设计和防风网工程的验收具有重要意义。提出一种计算防风网对露天煤堆PM_(2.5)的减排效果新方法。采用Fluent软件计算出煤堆前的最大风速值,并代入美国国家环保... 详细信息

科学评价防风网的减排效果,特别是其针对PM_(2.5)的减排率,对指导防风网优化设计和防风网工程的验收具有重要意义。提出一种计算防风网对露天煤堆PM_(2.5)的减排效果新方法。采用Fluent软件计算出煤堆前的最大风速值,并代入美国国家环保局(US EPA)推荐的露天堆场扬尘排量计算公式,分别计算出设置防风网前后露天煤堆PM_(2.5)的月排放量。结果表明,开孔率为40%的平面型防风网对露天煤堆的PM_(2.5)减排率可达99.33%。为了验证该计算方法的有效性,采用其他减排效果计算方法对此煤堆进行了计算,结果显示两种方法的计算结果相一致。

关键词：露天煤堆防风网 PM2.5 减排效果评估方法

A single dose pharmacokinetic and pharmacodynamic study of MEDI3617 in cynomolgus monkeys

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A single dose pharmacokinetic and pharmacodynamic study of M...

A single dose pharmacokinetic and pharmacodynamic study of MEDI3617 in cynomolgus monkeys

作者： liu yong-zhen WU Chi-yuan LU Hong YU Hong REN Jin Centre for Drug Safety Evaluation and Research Shanghai Institute of Materia Medica Medlmmune LLC.

OBJECTIVE MEDI3617 is a candidate pharmacological agent under development by *** study is designed to assess pharmacokinetic profiles and to fully characterize total and free angiopoietin-2(Ang2) responses after a single intravenous(Ⅳ) administration in cynomolgus *** Four male naive cynomolgus monkeys were assigned to this *** animals were given a single dose of 6 mg-kg"1 MEDI3617 via IV administration for approximately 30 *** recovery period was 56 *** samples were taken at different time points to assess expo sure of MEDI3617 and to fully characterize total and free Ang2 responses after a single IV *** Peak serum MEDI3617 concentration was attained generally at the first PK time point(1 h) post IV administration and declined biphasically *** observed mean values for maximum concentration was(213±38)mg·L~(-1),area under the serum concentration-time curve from time 0 to infinity was(1280±288) mg ? L~(-1)·d~(-1),clearance was(4.87±1.15) ml ? kg~(-1)? d~(-1),and half-life was(3.25±0.672)*** changes in free Ang2 levels were *** Ang2 concentrations were suppressed immediately after dosing(1 h) and quickly recovered back to baseline after approximately 12 *** Ang2 concentrations accumulated with a maximum accumulation of approximate 100 fold from baseline and recovered back to baseline after approximately 56 d after dosing.

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A single dose pharmacokinetic and pharmacodynamic study of M...

不同利用方式对红壤关键带孙家小流域土壤活性有机碳组分的影响

2013年（第三届）中国药物毒理学年会暨药物非临床安全性评价研究论坛

作者： liu yong-zhen WU Chi-yuan LU Hong YU Hong REN Jin Centre for Drug Safety Evaluation and Research Shanghai Institute of Materia Medica

OBJECTIVE MEDI3617 is a candidate pharmacological agent under development by *** study is designed to assess pharmacokinetic profiles and to fully characterize total and free angiopoietin-2(Ang2) responses after a single intravenous(Ⅳ) administration in cynomolgus *** Four male naive cynomolgus monkeys were assigned to this *** animals were given a single dose of 6 mg·kg MEDI3617 viaⅣadministration for approximately 30 *** recovery period was 56 *** samples were taken at different time points to assess exposure of MEDI3617 and to fully characterize total and free Ang2 responses after a single IV *** Peak serum MEDI3617 concentration was attained generally at the first PK time point(1 h) post IV administration and declined biphasically *** observed mean values for maximum concentration was(213±38)mg·L,area under the serum concentration-time curve from time 0 to infinity was(1280±288)mg·L·d,clearance was(4.87±1.15) ml·kg? d,and half-life was(3.25±0.672)*** changes in free Ang2 levels were *** Ang2 concentrations were suppressed immediately after dosing(1 h) and quickly recovered back to baseline after approximately 12 *** Ang2 concentrations accumulated with a maximum accumulation of approximate 100 fold from baseline and recovered back to baseline after approximately 56 d after dosing.

关键词： pharmacokinetic MEDI3617 pharmacodynamic

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江西农业大学学报 2019年第4期41卷 823-834页

作者：高振刘真勇王艳玲南京信息工程大学应用气象学院/生态气象环境研究中心

活性有机碳(AOC)是评价土壤质量的重要指标,是土壤有机碳库的重要组成部分。研究以江西省鹰潭市余江县孙家小流域红壤关键带观测站为依托,采集了老稻田(old paddy,OP)(>200年)、新稻田(new paddy,NP)(<30年)、旱地(upland,U)(<20年)、橘... 详细信息

活性有机碳(AOC)是评价土壤质量的重要指标,是土壤有机碳库的重要组成部分。研究以江西省鹰潭市余江县孙家小流域红壤关键带观测站为依托,采集了老稻田(old paddy,OP)(>200年)、新稻田(new paddy,NP)(<30年)、旱地(upland,U)(<20年)、橘园(orchard,O)(<30年)和林地(forest,F)(<30年)的表层土壤(0~15 cm)样本,分析了土壤总有机碳(TOC)、颗粒有机碳(POC)、易氧化有机碳(ROC)、水溶性有机碳(DOC)及微生物生物量碳(MBC)等活性有机碳组分的含量差异及春秋季变化,探讨了不同利用方式下关键带红壤中各形态活性有机碳组分的含量差异及其主要诱因。研究结果表明:红壤关键带中老稻田土壤TOC含量和密度及各组分活性碳含量均显著高于新稻田、旱地、橘园和林地;且只有稻田土壤DOC与旱地、橘园和林地土壤POC的春秋季变化差异显著。利用方式对土壤中各活性碳组分的存在比例影响差异显著,其中POC与ROC分别是稻田与旱地、橘园、林地土壤中所占比例最高的活性碳组分;而DOC则是所占比例最低的活性有机碳组分。相关性分析表明,不同利用方式红壤中DOC、MBC、ROC、POC与TOC之间均具有极显著的正相关关系。

关键词：利用方式红壤关键带活性有机碳稻田旱地

移动Ad Hoc网络通信量相关干扰感知路由协议

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软件学报 2009年第10期20卷 2721-2728页

作者：张信明刘琼代仕芳刘永振中国科学技术大学计算机科学与技术学院安徽合肥230027

干扰严重影响移动Adhoc网络的网络吞吐量、能量消耗、网络寿命等性能.在已有基于邻居数目和分布位置的干扰模型基础上,进一步考虑各邻居上的通信量情况,提出通信量干扰模型.并在该干扰模型的基础上,提出一个通信量相关干扰感知路由TIR(t... 详细信息

干扰严重影响移动Adhoc网络的网络吞吐量、能量消耗、网络寿命等性能.在已有基于邻居数目和分布位置的干扰模型基础上,进一步考虑各邻居上的通信量情况,提出通信量干扰模型.并在该干扰模型的基础上,提出一个通信量相关干扰感知路由TIR(traffic load-based interference-aware routing)协议.TIR通过在源节点和目的节点之间选择干扰最小的路径来降低数据包在转发过程中可能受到的干扰.模拟实验结果表明,所提出的通信量干扰模型符合移动Adhoc网络的特性,通信量相关干扰感知路由协议对网络寿命、通信延迟及吞吐量等网络性能有明显改善.

关键词：干扰路由协议邻居节点通信量移动ad hoc网络

A single dose pharmacokinetic and pharmacodynamic study of MEDI3617 in cynomolgus monkeys

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中国药理学与毒理学杂志 2013年第3期 544-544页

作者： liu yong-zhen WU Chi-yuan LU Hong YU Hong REN Jin Centre for Drug Safety Evaluation and Research Shanghai Institute of Materia Medica MedImmune LLC.HaywardCA 94545USA

OBJECTIVE MEDI3617 is a candidate pharmacological agent under development by *** study is designed to assess pharmacokinetic profiles and to fully characterize total and free angiopoietin-2(Ang2) responses after a single intravenous(IV) administration in cynomolgus *** Four male naive cynomolgus monkeys were assigned to this *** animals were given a single dose of 6 mg·kg-1 MEDI3617 via IV administration for approximately 30 *** recovery period was 56 *** samples were taken at different time points to assess exposure of MEDI3617 and to fully characterize total and free Ang2 responses after a single IV *** Peak serum MEDI3617 concentration was attained generally at the first PK time point(1 h) post IV administration and declined biphasically *** observed mean values for maximum concentration was(213 ± 38) mg·L-1,area under the serum concentration-time curve from time 0 to infinity was(1280 ± 288) mg·L-1.d-1,clearance was(4.87 ± 1.15) ***-1.d-1,and half-life was(3.25 ± 0.672) *** changes in free Ang2 levels were *** Ang2 concentrations were suppressed immediately after dosing(1 h) and quickly recovered back to baseline after approximately 12 *** Ang2 concentrations accumulated with a maximum accumulation of approximate 100 fold from baseline and recovered back to baseline after approximately 56 d after dosing.

关键词： pharmacokinetic MEDI3617 pharmacodynamic

THE MAINTENANCE OF GALACTIC DENSITY WAVE AND THE PHASE SHIFTS BETWEEN THE STELLAR AND GASEOUS ARMS

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Science in China,Ser.A 1979年第1期 69-80页

作者：刘永镇方励之 University of Science and Technology of China

In general, there are phase shifts between the stellar and gaseous arms in spiral galaxies. According to Lin’s density wave theory, the phase shifts are interpreted by shock wave mechanism. However, it is neither self-consistent nor easy to explain the observed characteristics quantitatively. It has been shown that the process of star formation and consequent heating of interstellar gas provides a mechanism for the excitation of galactic density waves and the maintenance of spiral structure. In the present paper, the problem is examined once again by the method of stellar dynamics. Specifically, it has been found that if the nonmechanical energy interchange is considered, both the problem of interpreting the phase shifts and that of maintenance may be resolved simultaneously. By using the non-neutral wave theory, it is easy to account the general properties of the phase shifts: (1) For a differentially rotating galaxy, the gaseous arm is separated from the stellar arm. (2) Between the inner Lindblad res

关键词：面口 THE MAINTENANCE OF GALACTIC DENSITY WAVE AND THE PHASE SHIFTS BETWEEN THE STELLAR AND GASEOUS ARMS