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Chinese Journal of Chemistry 2013年第7期31卷 885-891页

作者： Qingyu lin lingling Chu Feng-ling Qing Key Laboratory of Organofluorine Chemistry Shanghai Institute of Organic Chemistry Chinese Academy of Sciences 345 Lingling Lu Shanghai 200032 China College of Chemistry Chemical Engineering and Biotechnology Donghua University 2999 North Renmin Lu Shanghai 201620 China

A mild and versatile approach for the direct introduction of ethoxycarbonyldifluoromethyl-group to heteroarenes via visible-light photocatalysis has been developed. The new photoredox protocol has enabled the difluoro... 详细信息

关键词： difluoromethylenation heteroarenes visible-light photocatalysis

Formation mechanisms and sequence response of authigenic grain-coating chlorite: evidence from the Upper Triassic Xujiahe Formation in the southern Sichuan Basin, China

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Petroleum Science 2016年第4期13卷 657-668页

作者： Yu Yu Liang-Biao lin Jian Gao State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Chengdu University of Technology Institute of Sedimentary Geology Chengdu University of Technology

Authigenic grain-coating chlorite is widely distributed in the clastic rocks of many sedimentary basins around the world. These iron minerals were mainly derived from flocculent precipitates formed when rivers flow into the ocean, especially in deltaic environments with high hydrodynamic conditions. At the same time, sandstone sequences with grain-coating chlorites also tend to have relatively high glauconite and pyrite content. EPMA composition analysis shows that glauconites with ‘‘high Al and low Fe’’ content indicate slightly to semi-saline marine environments with weak alkaline and weakly reducing conditions. By analyzing the chlorite-containing sandstone bodies of the southern Sichuan Xujiahe Formation, this study found that chlorite was mainly distributed in sedimentary microfacies, including underwater distributary channels, distributary channels, shallow lake sandstone dams, and mouth bars. Chlorite had a tendency to form in the upper parts of sandstone bodies with signs of increased base level, representing the influence of marine（lacustrine）transgression. This is believed to be influenced by megamonsoons in the Middle and Upper Yangtze Region during the Late Triassic Epoch. During periods of abundant precipitation, river discharges increased and more Fe particulates flowed into the ocean（lake）. In the meantime,increases or decreases in lake level were only affected byprecipitation for short periods of time. The sedimentary environment shifted from weakly oxidizing to weak alkaline, weakly reducing conditions as sea level increased, and Fe-rich minerals as authigenic chlorite and glauconite began to form and deposit.

关键词： Sichuan Basin Xujiahe Formation Graincoating chlorite Glauconite Pyrite

Adsorption behaviors of avian immunoglobulins and purification of immunoglobulin Y from chicken serum with mixed-mode resins

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Chinese Journal of Chemical Engineering 2019年第3期27卷 514-518页

作者： Yingdi Luo Qilei Zhang Shanjing Yao Dongqiang lin Key Laboratory of Biomass Chemical Engineering of Ministry of Education College of Chemical and Biological Engineering Zhejiang University

The importance of immunoglobulin Y(IgY) as a specific antibody equivalent to mammalian immunoglobulin G(IgG) is well recognized. However, production of highly purified IgY is still difficult due to the lack of specific purification methods. In this study, adsorption behaviors of Ig Y on four mixed-mode resins with functional ligands of 4-mercatoethyl-pyridine(MEP), 2-mercapto-1-methyli-midazole(MMI), 5-aminobenzi-midazole(ABI) and tryptophan-5-aminobenzi-midazole(W-ABI) were evaluated. The results showed that high adsorption ratio were found at p H 6.0–7.0 with little adsorption under acidic conditions. The resin with ABI ligand was then used to separate IgY from immunized chicken serum. an efficient process with Ig Y purity of 95% and recovery of 90% was developed after optimization of loading and elution p H and injection volume. The biological activity of the purified Ig Y was fully maintained. These results indicated that mixed-mode chromatography with specially-designed ligands has great potential for the separation of Ig Y from crude feedstock.

关键词： Mixed-mode chromatography Immunoglobulin Y Adsorption selectivity Separation

Three-Qubit Entanglement Sudden Death

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Communications in Theoretical Physics 2008年第6期49卷 1443-1448页

作者： GE Min ZHU lin-Fan QIU Liang Hefei National Laboratory for Physical Sciences at Microscale Department of Modern Physics University of Science and Technology of China Hefei 230026 China Department of Modern Physics University of Science and Technology of China Hefei 230026 China

We study entanglement dynamics of three-qubit system via negativity. Three atoms A, B, and C interact isolatedly with their own Jaynes-Cummings cavities a, b, and c. Aa system is prepared entangled with Bb and Cc, however, their mutual isolations forbid Aa interacting with system Bb and Cc. It is the same for system Bb and Cc. We show entanglement evolution of different three-qubit systems ABC, abc, Abc, and aBC and find entanglement sudden death effect.

关键词： entanglement sudden death J-C models

Identification of Eye Movements from Non-frontal Face Images for Eye-controlled Systems

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International Journal of Automation and computing 2014年第5期11卷 543-554页

作者： Min lin Bin Li Qiao-Hong Liu School of Mechatronic Engineering and Automation Shanghai University Shanghai Medical Instrumentation College University of Shanghai Science and Technology

The novel eye-based human-computer interaction(HCI) system aims to provide people, especially, disabled persons,a new way of communication with surroundings. It adopts a series of continual eye movements as input to perform simple control activities. Identification of eye movements is the crucial technology in these eye-based HCI systems. At present, researches on eye movement identification mainly focus on frontal face images. In fact, acquisition of non-frontal face images is more reasonable in real applications. In this paper, we discuss the identification process of eye movements from non-frontal face images. Firstly, the original head-shoulder images of 0?–±60?azimuths are sampled without any auxiliary light source. Secondly, the non-frontal face region is detected by using the Adaboost cascade classifiers. After that, we roughly extract eye windows by the integral projection ***, we propose a new method to calculate the x- y coordinates of the pupil center point by searching the minimal intensity value in the eye windows. According to the trajectory of the pupil center points, different eye movements(eye moving left, right, up or down)are successfully identified. A set of experiments is presented.

关键词： Eye movement identification non-frontal face images pupil center localization human-computer interaction eye-based system

基于表观遗传修饰探究中医药防治抑郁症认知障碍研究进展

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亚太传统医药 2025年第1期21卷 196-199页

作者：林珊珊陈雅茹刘依婷林泓睿杨鹤鑫林玥谢丽霞沈建英福建中医药大学福建福州350122

抑郁症是全球发病率最高的精神疾病之一,认知障碍可发生在抑郁症病程的任何一个阶段。大量研究表明抑郁症认知障碍的发病机制大多以海马突触可塑性损伤和神经再生障碍为基础。基于中医学与表观遗传学的相关性,通过对近年来中医药干预疗... 详细信息

抑郁症是全球发病率最高的精神疾病之一,认知障碍可发生在抑郁症病程的任何一个阶段。大量研究表明抑郁症认知障碍的发病机制大多以海马突触可塑性损伤和神经再生障碍为基础。基于中医学与表观遗传学的相关性,通过对近年来中医药干预疗法调控表观遗传修饰改善抑郁症认知障碍的相关文献进行分析总结,以期为防治抑郁症认知障碍提供新视角。

关键词：中医药表观遗传修饰抑郁症认知障碍研究进展

The glyco-regioisomerism effect on dynamic interactions between glycopolymers with galactose pendants and benzoxaborole-containing polymer

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Science China Chemistry 2018年第1期61卷 71-75页

作者： Pengfei Sun Sichao Tian Mingchang lin Guosong Chen Key Laboratory for Organic Electronics and Information Displays & Institute of Advanced Materials Jiangsu National Synergetic Innovation Center for Advanced Materials Nanjing University of Posts & Telecommunications The State Key Laboratory of Molecular Engineering of Polymers and Department of Macromolecular Science Fudan University

This work investigated the effect of glyco-regioisomerism of glycopolymers on their dynamic interaction with benzoxaborole-containing polymers. Two kinds of glycopolymers, P-1-Gal and P-6-Gal, i.e. galactoside pendant group linked to the identical main chain through its anomeric(C1) and C6-hydroxyl group position, respectively, were studied. We found that P-6-Gal showed stronger binding strength to the PNIPAM-co-PBOB polymer than P-1-Gal did, which controlled the macroscopic property of the resultant hydrogels at a molecular level.

关键词： glyco-regioisomerism benzoxaborole glycopolymers hydrogel glucose

The matrix method for black hole quasinormal modes

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Chinese Physics C 2019年第3期43卷 117-125页

作者： Kai lin Wei-Liang Qian Hubei Subsurface Multi-scale Imaging Key Lab. Institute of Geophysics and GeomaticsChina University of GeosciencesHubei 430074China Escola de Engenharia de Lorena Universidade de S?o Paulo12602-810LorenaSPBrazil Faculdade de Engenharia de Guaratinguetá Universidade Estadual Paulista12516-410GuaratinguetáSPBrazil School of Physical Science and Technology Yangzhou UniversityJiangsu 225002China

We provide a comprehensive survey of possible applications of the matrix method for black hole quasinormal modes. The proposed algorithm can generally be applied to various background metrics, and in particular, it accommodates both analytic and numerical forms of the tortoise coordinates, as well as black hole spacetimes. We give a detailed account of different types of black hole metrics, master equations, and the corresponding boundary conditions. Besides, we argue that the method can readily be applied to cases where the master equation is a system of coupled equations. By adjusting the number of interpolation points, the present method provides a desirable degree of precision, in reasonable balance with its efficiency. The method is flexible and can easily be adopted to various distinct physical scenarios.

关键词： quasinormal modes black hole spacetime matrix method quasinormal frequency

Synthetic Automations:A Revolution from"Stone Age"to Modern Era

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Chinese Journal of Chemistry 2023年第9期41卷 1075-1079页

作者： Guichun Fang Dian-Zhao lin Kuangbiao Liao Guangzhou Laboratory GuangzhouGuangdong 510320China

Traditional synthesis made outstanding achievements but still suffers various drawbacks,such as manual operation,poor efficiency,and lack of *** to the development of laboratory automation,synthetic chemistry is now chasing a pavement from a labor-intensive process to intelligent ***,we highlight some of the most recent representative breakthroughs in automated synthesis and present an outlook for this *** hope this Topic can arouse chemists'interest in automated synthe-sis and drive synthetic automation to a better intelligent and automatic way.

关键词： Automated synthesis Organic synthesis AutomationAl-driven Artificial intelligence Machine Learning Flow chemistry

The arsenal of TP53 mutants therapies:neoantigens and bispecific antibodies

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Signal Transduction and Targeted Therapy 2021年第7期6卷 1935-1936页

作者： Chang Yang Ge Lou Wei-lin Jin Department of Gynecology Oncology The Tumor HospitalHarbin Medical UniversityHarbinP.R.China lnstitute of Cancer Neuroscience Medical Frontier Innovation Research CenterThe First Hospital of Lanzhou UniversityThe First Clinical Medical College of Lanzhou UniversityLanzhouP.R.China

A recent research published in Science by Hsiue et al.1 introduced a CD3-targeting bispecific antibody that can bind to tumor cells by recognizing mutation-associated neoantigens and activate T cell-mediated tumor kil... 详细信息

关键词： TP53 antigens