检索结果-南通市图书馆

Distribution characteristics of photoinitiators and their flux estimation from the Pearl River Delta to the coastal waters of the South China Sea

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2023年第6期128卷 71-80页

作者： yuqing He Zibin Pan Xinxin liang Ruiman Xie Yuying Sun Juan Li YaweiWang Lixi Zeng Guangdong Key Laboratory of Environmental Pollution and Health School of EnvironmentJinan UniversityGuangzhou 511443China Guangdong-Hongkong-Macao Joint Laboratory of Collaborative Innovation for Environmental Quality Jinan UniversityGuangzhou 511443China Research Center for Eco-Environmental Sciences Chinese Academy of SciencesBeijing 100085China

Photoinitiators(PIs)are widely used in industrial polymerization *** has been reported that PIs are ubiquitous in indoor environments and that humans are exposed to PIs,but the occurrence of PIs in natural environments are rarely *** the present study,25 PIs,including 9 benzophenones(BZPs),8 amine co-initiators(ACIs),4 thioxanthones(TXs)and 4 phosphine oxides(POs),were analyzed in water and sediment samples collected from eight riverine outlets of the Pearl River Delta(PRD).Eighteen,14,and 14 of the 25 target PIs were detected in water,suspended particulatematter(SPM)and sediment samples,*** total concentrations of PIs in water,SPM,and sediment were in the ranges of 2.88–96.1 ng/L,9.25–923 ng/g dry weight(dw),and 3.79–56.9 ng/g dw,with geometric mean concentration(GM)of 10.8 ng/L,48.6 ng/g dw,and 17.1 ng/g dw,respectively.A significant linear regression was observed between the log partitioning coefficients(Kd)values of PIs and their log octanol water partition coefficient(Kow)values(R^(2)=0.535,p<0.05).The annual riverine input of PIs to the coastal waters of the South China Sea via eightmain outlets of the PRD was estimated to be 4.12×10^(3)kg/year,and the∑BZPs,∑ACIs,∑TXs and∑POs contributed to 1.96×10^(3),1.24×10^(3),89.6 and 830 kg/year,*** is the first report of a systematic description of the occurrence characteristics of PIs exposure in water,SPM,and *** environmental fate and risks of PIs in aquatic environments need further investigations.

关键词： Photoinitiators Riverine inputs Distribution characteristics Partitioning coefficients Pearl River Delta

Synthesis, Characterization and Application of Organic-inorganic Hybrid and Carbaryl-imprinted Capillary Monolithic Column

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2014年第3期30卷 374-378页

作者： ZHANG Can CAI Jianrong DUAN yuqing XU liang FANG Guozhen WANG Shuo School of Food & Biological Engineering Jiangsu University Zhenjiang 212013 P. R. China Tianjin Key Laboratory on Technologies Enabling Development Clinical Therapeutics and Diagnostics(Theranostics) School of Pharmacy Tianjin Medical University Tianjin 300070 P. R. China Faculty of Food Engineering and Biotechnology Tianjin University of Science and Technology Tianjin 300457 P. R. China

Organic-inorganic hybrid and carbaryl-imprinted capillary monolith was synthesized via methacrylic acid（MAA） as functional monomer, γ-methacryloxypropyltrimethoxysilane（γ-MAPS） as crosslinker and carbaryl as template molecule in an acetonitrile/dichloromethane mixture（1：4, volume ratio）. With the capillary column obtained from this monolith, three carbamates（carbaryl, fenobucarb and metolcarb） were separated effectively by electrochromatography with the kMIp/kNlP values of 7.57, 1.27 and 1.64, respectively. In 20 mmol/L phosphate buffer solution（pH=3.5） with 30%（volume fraction） of acetonitrile, carbaryl was separated directly from the three-carbamate mixture（carbaryl, fenobucarb and metolcarb） with an effective 15 cm-length imprinted column.

关键词： Organic-inorganic hybrid Carbaryl-imprinted capillary Monolith Separate

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

贵州省汇川区药用植物资源调查

贵州农业科学 2023年第1期51卷 98-106页

作者：朱亮宋德勋梁晴韦德群谭怀美邱佳陈玉宝梁玉清罗红波伍明江遵义医药高等专科学校药学系贵州遵义563006

【目的】探明贵州省遵义市汇川区野生药用植物资源的种类及栽培药用植物的现状,为当地野生中药资源的保护、开发及优势品种推广提供依据。【方法】根据第四次全国中药资源普查技术规范要求,采用实地踏查法结合走访调查对汇川区43个样地... 详细信息

【目的】探明贵州省遵义市汇川区野生药用植物资源的种类及栽培药用植物的现状,为当地野生中药资源的保护、开发及优势品种推广提供依据。【方法】根据第四次全国中药资源普查技术规范要求,采用实地踏查法结合走访调查对汇川区43个样地药用植物资源及栽培品种进行调查。【结果】汇川区的药用植物资源分属116科336属515种,其中,优势科有菊科(48种,占比9.32%),蔷薇科(27种,占比5.24%)及百合科(26种,占比5.05%)等共10个科;根据入药部位可分为全草类、果实及种子类和叶类等共8类,以全草类最多(221种);根据功效可划分为解表类、清热类及泻下类等19类,以清热类最多(182种)。汇川区发现贵州省重点中药品种48科85种,包含菝葜、吉祥草、野葛、杜仲、千里光、杠板归及三叶木通等;银杏、珙桐和红豆杉为国家重点Ⅰ级保护野生植物,西南舌唇兰、润楠、喜树和金荞麦等14种药用植物为国家重点Ⅱ级保护野生植物。汇川区栽培药用植物共计21种,包括天麻、五倍子及黄精等,种植面积约3200 hm^(2)。【结论】汇川区药用植物资源蕴藏量大,多样性丰富,建议适当发展当地优势中药品种种植。

关键词：中药资源普查药用植物中药材汇川贵州

Omics for deciphering oral microecology

在线全文

学校读者我要写书评

暂无评论

International Journal of Oral Science 2024年第2期16卷 197-207页

作者： Yongwang Lin Xiaoyue liang Zhengyi Li Tao Gong Biao Ren yuqing Li Xian Peng State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases West China Hospital of StomatologySichuan UniversityChengduChina

The human oral microbiome harbors one of the most diverse microbial communities in the human body,playing critical roles in oral and systemic *** technological innovations are propelling the characterization and manipulation of oral ***-throughput sequencing enables comprehensive taxonomic and functional profiling of oral *** long-read platforms improve genome assembly from complex ***-cell genomics provides insights into uncultured *** imaging modalities including fluorescence,mass spectrometry,and Raman spectroscopy have enabled the visualization of the spatial organization and interactions of oral microbes with increasing *** techniques link phylogenetic identity with *** spectrometry imaging reveals metabolic niches and activities while Raman spectroscopy generates rapid biomolecular fingerprints for *** facilitates the isolation and cultivation of novel fastidious oral taxa using high-throughput *** integration of these technologies holds the promise of transforming our understanding of oral microbiome assembly,gene expression,metabolites,microenvironments,virulence mechanisms,and microbe-host interfaces in the context of health and ***,significant knowledge gaps persist regarding community origins,developmental trajectories,homeostasis versus dysbiosis triggers,functional biomarkers,and strategies to deliberately reshape the oral microbiome for therapeutic *** convergence of sequencing,imaging,cultureomics,synthetic systems,and biomimetic models will provide unprecedented insights into the oral microbiome and offer opportunities to predict,prevent,diagnose,and treat associated oral diseases.

关键词： insight holds oral

Charge-reversible crosslinked nanoparticle for pro-apoptotic peptide delivery and synergistic photodynamic cancer therapy

在线全文

学校读者我要写书评

暂无评论

Nano Research 2023年第12期16卷 13267-13282页

作者： Haijing Qu Han Chen Wei Cheng yuqing Pan Zhiran Duan Yanjun Wang Xing-Jie liang Xiangdong Xue Shanghai Frontiers Science Center of Drug Target Identification and Delivery School of PharmacyShanghai Jiao Tong UniversityShanghai 200240China National Key Laboratory of Innovative Immunotherapy Shanghai Jiao Tong UniversityShanghai 200240China Shanghai Ninth People’s Hospital Shanghai Jiao Tong University School of MedicineShanghai 200011China CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety CAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190China

Although anti-cancer nanotherapeutics have made breakthroughs,many remain clinically unsatisfactory due to limited delivery efficiency and complicated biological ***,we prepared charge-reversible crosslinked nanoparticles(PDC NPs)by supramolecular self-assembly of pro-apoptotic peptides and photosensitizers,followed by crosslinking the self-assemblies with polyethylene glycol to impart tumor microenvironment responsiveness and *** resultant PDC NPs have a high drug loading of 68.3%,substantially exceeding that of 10%–15%in conventional drug delivery *** NPs can overcome the delivery hurdles to significantly improve the tumor accumulation and endocytosis of payloads by surface charge reversal and responsive crosslinking ***-apoptotic peptides target the mitochondrial membranes and block the respiratory effect to reduce local oxygen consumption,which extensively augments oxygen-dependent photodynamic therapy(PDT).The photosensitizers around mitochondria increased along with the peptides,allowing PDT to work with pro-apoptotic peptides synergistically to induce tumor cell death by mitochondria-dependent apoptotic *** strategy would provide a valuable reference for improving the delivery efficiency of hydrophilic peptides and developing mitochondrial-targeting cancer therapies.

关键词： charge-reversible nanoparticle crosslinked nanoparticle peptide delivery photodynamic therapy synergistic cancer treatment

Accelerometer Bias and Star Sensor Installation Error Joint Calibration for the SINS/CNS Integrated Navigation System Using Attitude Maneuver

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Guidance, Navigation and Control 2022年第2期2卷 18-32页

作者： Xiaolin Ning yuqing Yang Xiaoyu liang Jie Zhang Research Institute for Frontier Science Beihang University(BUAA)Beijing 100191P.R.China School of Instrumentation Science&Opto-electronics Engineering Beihang University(BUAA)Beijing 100191P.R.China

The integrated strap-down inertial nav igation system/olelestial navigation system(SINS/CNS)i an important autonomous navigation method with efective concealment and high *** accelerometer biss and star ensor installation error ame important factors that aflect the performanoe of this mavigation system,which needl to be calibratexd and compensatedl.A new acelerometer bias and star sensor installation error joint calibration method for the SINS/CNS integrated navigation system i *** this newly propoeed method,the installation error of star sensor is augmented to the state vector,and the star vector,nadir angle,horkzontal poeition error and velbcity error ame ueed a8 measurementa to calbrate the two errors mentioned *** show that both accelerometer bias and star sensor installation enror an be calibratedl efectively.

关键词： SINS/CNS integrated navigation accelerometer bias star sensor installation error calibration method

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

贵州省红花岗区药用植物资源调查

贵州农业科学 2021年第6期49卷 90-98页

作者：梁晴韦德群宋德勋朱亮谭怀美邱佳陈玉宝梁玉清冉海霞罗红波伍明江遵义医药高等专科学校贵州遵义563000

【目的】摸清贵州省红花岗区药用植物资源种类及利用现状,为当地药用植物资源的保护、开发利用提供科学依据。【方法】以第四次全国中药资源普查技术规范为指导,对贵州省红花岗区40个有效样地,200个样方套药用植物资源及栽培现状进行调... 详细信息

【目的】摸清贵州省红花岗区药用植物资源种类及利用现状,为当地药用植物资源的保护、开发利用提供科学依据。【方法】以第四次全国中药资源普查技术规范为指导,对贵州省红花岗区40个有效样地,200个样方套药用植物资源及栽培现状进行调查,对药用植物资源构成的特点、中药性能及功效等进行统计分析。【结果】红花岗区药用植物105科256属320种,含豆科和菊科两大优势科;国家Ⅰ级和Ⅱ级保护植物共13种,包括春兰、南方红豆杉及苏铁等4种国家Ⅰ级保护植物,斑叶兰、小舌唇兰及见血青等9种国家Ⅱ级保护植物;生活型以草本为主;入药部位以全草入药种类居多;功效分类中清热药居多;现行版药典收录92种;药食同源药物44种;红花岗区中药材种植面积累计0.153万hm^(2),产量2.53万t,主要涉及金银花、杜仲及黄柏等品种。【结论】红花岗区药用植物资源物种多样性丰富。该研究大致掌握了红花岗区野生、栽培中药资源种类和蕴藏量,可为保护红花岗区中药资源、促进中药产业健康发展、推动中药材经济发展提供参考依据。

关键词：中药资源普查药用植物资源红花岗区贵州

Bi-functional selection markers assist segregation of transgene-free,genome-edited mutants

在线全文

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2021年第9期64卷 1567-1570页

作者： Zhen liang yuqing Wu Yingjie Guo Yanxiu Liu Lingling Ma Yincen Wu School of Life Science Shanxi UniversityTaiyuan 030006China Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of ChinaChengdu 610000China

Dear Editor,In recent years,CRISPR/Cas9-mediated genome editing has been successfully applied in various plants for functional analysis or crop improvement(Chen et al.,2019).We previously reported DNA-free genome-edit... 详细信息

关键词： CRISPR/Cas9 genome functional

“任务驱动—混合教学”模式在中药学课程教学中的探索

在线全文

学校读者我要写书评

暂无评论

创新创业理论研究与实践 2023年第20期6卷 139-144页

作者：梁晴冉海霞李飞雁陈玉宝杨显娟梁玉清邱佳韦德群刘英波遵义医药高等专科学校贵州遵义563006 天津中医药大学天津300193

该文以大健康背景下中医专业中药学课程的教学模式改革为例,设立传统教学对照组与改革实践组,模拟临床用药,丰富教学环节,融入思政元素,探索“以任务为驱动、以学生为中心、以教师为主导”的“线下+线上”混合教学模式,采用多元的评价方... 详细信息

该文以大健康背景下中医专业中药学课程的教学模式改革为例,设立传统教学对照组与改革实践组,模拟临床用药,丰富教学环节,融入思政元素,探索“以任务为驱动、以学生为中心、以教师为主导”的“线下+线上”混合教学模式,采用多元的评价方法,量化检验学生学习效果,以期提高中药学课程的教学质量,使学生能灵活掌握中药药性理论及临床应用,为培养具有辨证用药、指导患者合理用药能力的中医专业人才奠定基础。

关键词：中药学中医专业任务驱动混合教学教学改革课程教学