检索结果-南通市图书馆

维普期刊数据库博看期刊

Experimental investigation of regular wave propagation over an idealized reef model

在线全文

学校读者我要写书评

暂无评论

Journal of Hydrodynamics 2020年第4期32卷 717-726页

作者： Gan-cheng Zhu bing ren Hong-jie Wen guo-yu wang yong-xue wang State Key Laboratory of Coastal and Offshore Engineering Dalian University of TechnologyDalian 116024China

The wave transformation over the deep-sea coral reefs is an essential issue in the analysis of the reef ecosystem and the design of large reef-top *** wave flume experiments are conducted to investigate the wave transformation processes over an idealized reef *** measurements of the wave height,the wave set-up and the wave-generated flow on the reef-top are made with and without the reef-top structure at various submerged depths and under different wave *** is found that the reef-top structure has a significant influence on the wave breaking,the wave set-up and the wave-generated *** wave set-up increases with the increasing wave height and the decreasing submergence ***,the relationship between the wave set-up and the wave period is complex,influenced by the reef-top structure.

关键词： Coral reef wave set-up reef-top structure wave breaking wave-generated flow

GTF2H4 regulates partial EndMT via NF-κB activation through NCOA3 phosphorylation in ischemic diseases

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Innovation 2024年第2期5卷 27-41页

作者： Zheyan Fang Gang Zhao Shuang Zhao xueting yu Runyang Feng You-en Zhang Haomin li Lei Huang Zhenyang guo Zhentao Zhang Mukaddas Abdurahman Hangnan Hong Peng li bing Wu Jinhang Zhu Xin Zhong Dong Huang Hao Lu Xin Zhao Zhaoyang Chen Wenbin Zhang Junjie guo Hongchao Zheng yue He Shengying Qin Haojie Lu yun Zhao Xiangdong wang Junbo Ge Hua li Department of Cardiology Zhongshan HospitalFudan UniversityShanghai Institute of Cardiovascular DiseasesShanghai 200032China Department of Cardiology Zhongshan HospitalFudan UniversityShanghai 200032China Department of Medical Examination Shanghai Xuhui District Central HospitalShanghai 200031China Department of Cardiology and Institute of Clinical Medicine Renmin HospitalHubei University of MedicineShiyan 442000China Clinical Data Center Children’s HospitalZhejiang University School of MedicineNational Clinical Research Center for Child HealthHangzhou 310052China Department of Molecular Celland Cancer BiologyUniversity of Massachusetts Chan Medical SchoolWorcesterMA 01605USA Bio-X Institute Key Laboratory for The Genetics of Developmental and Neuropsychiatric DisordersShanghai Jiao Tong UniversityShanghai 200030China Department of Cardiology Heart Center of Fujian ProvinceFujian Medical University Union HospitalFuzhou 350001China Department of Cardiology Sir Run Run Shaw Hospitalaffiliated with Zhejiang University School of MedicineHangzhou 310020China Department of Cardiology The Affiliated Hospital of Qingdao UniversityQingdao 266003China Department of Cardiology Shanghai Xuhui District Central HospitalShanghai 200031China Department of Cardiology Shanghai Eighth People’s HospitalShanghai 200235China Department of Chemistry and Institutes of Biomedical Sciences Fudan UniversityShanghai 200032China State Key Laboratory of Cell Biology Shanghai Institute of Biochemistry and Cell BiologyCenter for Excellence in Molecular Cell ScienceChinese Academy of SciencesUniversity of Chinese Academy of SciencesShanghai 200031China School of life Science and Technology Shanghai Tech University100 Haike RoadShanghai 201210China Key Laboratory of Systems Health Science of Zhejiang Province School of Life ScienceHangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesHangzhou 310024China Department of Pulmonary and Critical Care Medicine Zhongshan Hospital

Partial endothelial-to-mesenchymal transition(EndMT)is an intermediate phenotype observed in endothelial cells(ECs)undergoing a transition toward a mesenchymal state to support neovascularization during(patho)physiological ***,we investigated the occurrence of partial EndMT in ECs under hypoxic/ischemic conditions and identified general transcription factor IIH subunit 4(GTF2H4)as a positive regulator of this *** addition,we discovered that GTF2H4 collaborates with its target protein excision repair cross-complementation group 3(ERCC3)to co-regulate partial ***,by using phosphorylation proteomics and site-directed mutagenesis,we demonstrated that GTF2H4 was involved in the phosphorylation of receptor coactivator 3(NCOA3)at serine 1330,which promoted the interaction between NCOA3 and p65,resulting in the transcriptional activation of NF-κB and the NF-kB/Snail signaling axis during partial *** vivo experiments confirmed that GTF2H4 significantly promoted partial EndMT and angiogenesis after ischemic ***,our findings reveal that targeting GTF2H4 is promising for tissue repair and offers potential opportunities for treating hypoxic/ischemic diseases.

关键词： ischemic activation GTF

Incidence and prognosis of olfactory and gustatory dysfunctions related to SARS-CoV-2 Omicron strain infection in China:A national multicenter survey of 35,566 individuals

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第2期10卷 113-120页

作者： Meng-Fan liu Rui-Xia Ma Xian-Bao Cao Hua Zhang Shui-Hong Zhou Wei-Hong Jiang yan Jiang Jing-Wu Sun Qin-Tai yang xue-Zhong li Ya-Nan Sun li Shi Min wang Xi-Cheng Song Fu-Quan Chen Xiao-Shu Zhang Hong-Quan Wei Shao-Qing yu Dong-Dong Zhu Luo Ba Zhi-Wei Cao Xu-Ping Xiao Xin Wei Zhi-Hong lin Feng-Hong Chen Chun-Guang Shan Guang-Ke wang Jing Ye Shen-Hong Qu Chang-Qing Zhao Zhen-lin wang Hua-Bin li Feng liu Xiao-Bo Cui Sheng-Nan Ye Zheng liu yu Xu Xiao Cai Wei Huang Ru-Xin Zhang yu-lin Zhao guo-Dong yu Guang-Gang Shi Mei-Ping Lu yang Shen yu-Tong Zhao Jia-Hong Pei Shao-bing Xie Long-Gang yu Ye-Hai liu Shao-Wei Gu yu-Cheng yang Lei Cheng Jian-Feng liu Graduate School of Beijing University of Chinese Medicine BeijingChina Department of Otorhinolaryngology Head and Neck Surgery China-Japan Friendship HospitalBeijingChina Department of Otorhinolaryngology Head and Neck Surgery The First People's Hospital of YinchuanYinchuanChina Department of Otorhinolaryngology The First People's Hospital of Yunnan ProvinceKunmingChina Department of Otorhinolaryngology The First Affiliated Hospital of Xinjiang Medical UniversityUrumqiChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of Zhejiang University School of MedicineHangzhouChina Department of Otorhinolaryngology Head and Neck Surgery Xiangya Hospital Central South UniversityChangshaChina Department of Otorhinolaryngology Head and Neck Surgery The Affiliated Hospital of Qingdao UniversityQingdaoChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of USTCHefeiChina Department of Otorhinolaryngology Head and Neck Surgery The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouChina Department of Otorhinolaryngology Head and Neck Surgery Qilu Hospital of Shandong UniversityJinanChina Department of Otorhinolaryngology Head and Neck Surgery The Second Affiliated Hospital of Harbin Medical UniversityHarbinChina Department of Otolaryngology The Second Hospital of Shandong UniversityShandong UniversityJinanChina Department of Otorhinolaryngology Head and Neck Surgery Peking University People's HospitalBeijingChina Department of Otorhinolaryngology Head and Neck Surgery Yantai Yuhuangding HospitalQingdao UniversityYantaiChina Department of Otorhinolaryngology Head and Neck Surgery Xijing HospitalThe Fourth Military Medical UniversityXi'anChina Gansu Provincial Center for Disease Control and Prevention LanzhouChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of China Medical UniversityShenyangChina Department of Otorhinolaryngology Head and Neck Surgery Tongji Hospit

Objective:This cross-sectional study aimed to determine the epidemiology of olfactory and gustatory dysfunctions related to COVID-19 in ***:This study was conducted by 45 tertiary Grade-A hospitals in *** and offline questionnaire data were obtained from patients infected with COVID-19 between December 28,2022,and February 21,*** collected information included basic demographics,medical history,smoking and drinking history,vaccination history,changes in olfactory and gustatory functions before and after infection,and other postinfection symptoms,as well as the duration and improvement status of olfactory and gustatory ***:Complete questionnaires were obtained from 35,566 *** overall incidence of olfactory and taste dysfunction was 67.75%.Being female or being a cigarette smoker increased the likelihood of developing olfactory and taste *** received four doses of the vaccine or having good oral health or being a alcohol drinker decreased the risk of such *** infection,the average olfactory and taste VAS scores were 8.41 and 8.51,respectively;after infection,they decreased to 3.69 and 4.29 and recovered to 5.83 and 6.55 by the time of the *** median duration of dysosmia and dysgeusia was 15 and 12 days,respectively,with 0.5%of patients having symptoms lasting for more than 28 *** overall self-reported improvement rate was 59.16%.Recovery was higher in males,never smokers,those who received two or three vaccine doses,and those that had never experienced dental health issues,or chronic accompanying ***:The incidence of dysosmia and dysgeusia following infection with the SARS-CoV-2 virus is high in *** and prognosis are influenced by several factors,including sex,SARS-CoV-2 vaccination,history of head-facial trauma,nasal and oral health status,smoking and drinking history,and the persistence of accompanying symptoms.

关键词： epidemiologic studies incidence olfactory disorders prognosis SARS-CoV-2 taste disorders

Paragonimiasis misdiagnosed as liver abscess:A case report

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第21期12卷 4807-4812页

作者： Ying-Qi Zheng Gong-bing guo Mei-Fang wang He-Zhong Zhu Chan Zhou lin-Hong li Lu Zhang yu-Quan liu Department of General Practice Taihe HospitalHubei University of MedicineShiyan 442000Hubei ProvinceChina Department of Pulmonary and Critical Care Medicine Taihe HospitalHubei University of MedicineShiyan 442000Hubei ProvinceChina

BACKGROUNDParagonimiasis is a typical food-borne zoonotic disease. Hosts acquire Paragonimusinfection through the ingestion of raw or undercooked crayfish and *** clinical manifestations of the disease are varied, and it is often misdiagnosedor missed. The diagnosis of paragonimiasis should be considered *** is the first choice for treatment, and albendazole can beused in combination with repeated courses in severe *** SUMMARYWe report a case of liver paragonimiasis that was misdiagnosed as an abscess. Thepatient presented with fatigue and poor appetite for 2 months, and was diagnosedwith liver abscess in the local hospital. After 6 months, the patient visited ourhospital because of recurrent abdominal pain and was diagnosed with liverparagonimiasis based on epidemiological history, clinical presentations, andlaboratory findings. He was treated with praziquantel (25 mg/kg) three times aday for 3 days;however, the symptoms still presented after treatment. He wastreated with oral praziquantel and albendazole for one further course. Follow-upsuggested that the treatment was effective and the symptoms *** combination of albendazole and praziquantel may improve the therapeuticefficacy of paragonimiasis.

关键词： liver paragonimiasis liver abscess Misdiagnosis Albendazole Praziquantel Case report

Towards an actionable One Health approach

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

贫困所致传染病(英文) 2024年第2期13卷 77-82页

作者： Zhang Xiao-Xi Lederman Zohar Han Le-Fei Schurer Janna M. Xiao li-Hua Zhang Zhi-bing Chen Qiu-Lan Pfeiffer Dirk Ward Michael P. Sripa Banchob Gabri?l Sarah Dhama Kuldeep Acharya Krishna Prasad Robertson Lucy J. Deem Sharon L. Aenishaenslin Cécile Dantas-Torres Filipe Otranto Domenico Grace Delia wang yang li Peng Fu Chao Poeta Patrícia Rahman Md. Tanvir Kassegne Kokouvi Zhu yong-Zhang Yin Kun liu Jiming wang Zhao-Jun guo Xiao-Kui Gong Wen-Feng Schwartl?nder Bernhard ren Ming-Hui Zhou Xiao-Nong School of Global Health Chinese Center for Tropical Diseases Research Shanghai Jiao Tong University School of Medicine Shanghai People’s Republic of China Institute of One Health Shanghai Jiao Tong University Shanghai People’s Republic of China Medical Ethics and Humanities Unit Hong Kong University Hong Kong People’s Republic of China Center for One Health University of Global Health Equity Butaro Rwanda College of Veterinary Medicine South China Agricultural University Guangzhou People’s Republic of China School of Ecology and Environment Hainan University Haikou Hainan People’s Republic of China Branch of animal and vector-borne diseases Division of Infectious Disease Control Chinese Center for Disease Control and Prevention Beijing People’s Republic of China Centre for Applied One Health Research and Policy Advice Department of Infectious Diseases and Public Health Jockey Club College of Veterinary Medicine and Life Sciences City University of Hong Kong Hong Kong SAR People’s Republic of China Department of Pathobiology and Population Sciences Royal Veterinary College London United Kingdom Sydney School of Veterinary Science The University of Sydney Camden Australia Tropical Disease Research Center Department of Tropical Medicine Faculty of Medicine Khon Kaen University Khon Kaen Thailand Laboratory of foodborne parasitic zoonoses Department of translational physiology infectiology and public health Chair Faculty Committee on Internationalisation Faculty of Veterinary Medicine Ghent University Merelbeke Belgium Division of Pathology ICAR-Indian Veterinary Research Institute (IVRI) Bareilly Uttar Pradesh India Department of livestock Services Animal Quarantine Office-Kathmandu Budhanilkantha Kathmandu Nepal Parasitology Department of Paraclinical Sciences Faculty of Veterinary Medicine Norwegian University of Life Sciences ?s Norway One Government Drive Saint Louis Zoo Institute for Conservation Medicine St. Louis USA Groupe de Recherche en épidémi

Background Despite the increasing focus on strengthening One Health capacity building on global level, challenges remain in devising and implementing real-world interventions particularly in the Asia-Pacific region. Recognizing these gaps, the One Health Action Commission (OHAC) was established as an academic community for One Health action with an emphasis on research agenda setting to identify actions for highest *** text This viewpoint describes the agenda of, and motivation for, the recently formed OHAC. Recognizing the urgent need for evidence to support the formulation of necessary action plans, OHAC advocates the adoption of both bottom-up and top-down approaches to identify the current gaps in combating zoonoses, antimicrobial resistance, addressing food safety, and to enhance capacity building for context-sensitive One Health *** By promoting broader engagement and connection of multidisciplinary stakeholders, OHAC envisions a collaborative global platform for the generation of innovative One Health knowledge, distilled practical experience and actionable policy advice, guided by strong ethical principles of One Health.

关键词： One Health Global Health One Health Action Commission Research agenda

基于氧化聚合规律和特征质谱信息鉴定云南红茶中的新型茶黄素

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

分析化学 2024年第6期52卷 846-867页

作者：李咏琳郭洁俞之豪李斯屿胡永丹易伦朝任达兵昆明理工大学食品科学与工程学院

茶黄素类化合物（TFs）是红茶中决定感官品质的一类重要物质，具有显著的生物活性。茶叶中除了存在4种常见的TFs外，还存在许多其它具有类似化学结构的茶黄素类似物（TFAs）。针对TFs及TFAs，本研究采用超高效液相色谱-高分辨质谱（UPLC... 详细信息

茶黄素类化合物（TFs）是红茶中决定感官品质的一类重要物质，具有显著的生物活性。茶叶中除了存在4种常见的TFs外，还存在许多其它具有类似化学结构的茶黄素类似物（TFAs）。针对TFs及TFAs，本研究采用超高效液相色谱-高分辨质谱（UPLC-HRMS）技术，结合该类成分的特征结构及一、二级质谱信息，提出了基于氧化聚合规律和特征质谱信息的TFAs识别和鉴定方法。通过分析现有TFs的氧化聚合过程，总结形成TFs的理论反应模型，并基于此计算潜在成分的前体离子值；同时，根据标准品和文献数据分析TFs的质谱裂解规律，总结该类成分的特征碎片离子及中性丢失碎片。最终，基于计算获得的前体离子值以及特征碎片离子或中性丢失信息，从原始的色谱-质谱数据中共鉴定出36种TFAs，其中6种为首次报道，并采用体外合成实验进行了部分验证。基于36种成分的定性和定量分析结果，采用偏最小二乘判别分析（PLS-DA）研究了这些成分在红茶加工中的变化，结果表明，TFAs可用于有效区分红茶发酵前后的样品。

关键词：茶黄素氧化缩合质谱中性丢失特征碎片离子

来源：博看期刊

河南黄河改道区浅层地下水化学特征与主控污染源解析

在线全文

学校读者我要写书评

暂无评论

环境科学 2024年第2期45卷 792-801页

作者：王帅任宇郭红曹文庚李祥志肖舜禹河南省自然资源监测和国土整治院郑州450061 自然资源部黄河流域中下游水土资源保护与修复重点实验室郑州450061 中国地质科学院水文地质环境地质研究所石家庄050061 自然资源部地下水科学与工程重点实验室石家庄050061 华北水利水电大学地球科学与工程学院郑州450046

黄河下游的河南北部平原是黄河频繁发生改道的地区.该地区浅层地下水水质较差且超标组分类型多,但是多种因素影响下各环境因子对水质的贡献作用仍需进一步得到量化.为了明确研究区浅层地下水的水质成因,采集330组浅层地下水样品进行区... 详细信息

黄河下游的河南北部平原是黄河频繁发生改道的地区.该地区浅层地下水水质较差且超标组分类型多,但是多种因素影响下各环境因子对水质的贡献作用仍需进一步得到量化.为了明确研究区浅层地下水的水质成因,采集330组浅层地下水样品进行区域性水质调查,通过主成分-绝对主成分得分-多元线性回归(PCA-APCS-MLR)模型揭示豫北黄河改道区的浅层地下水水质演化来源.结果表明,研究区浅层地下水超标率从高到低依次为:锰>铁>总硬度>溶解性总固体>钠>氟>砷>氯离子>硫酸根>铵根,特别是锰的超标率达到76%.水-岩溶滤富集作用、土壤来源、氧化还原条件和农业活动这4种因素是导致地下水水质较差的主要原因,四者方差累积解释率达到71.24%,同时地表水的补给也会影响地下水质.新乡等北部的黄河故道区地下水中,铁、砷、铵根、总硬度和TDS等组分主要受到水-岩溶滤作用和氧化还原条件影响造成浓度增加;黄河沿岸的水-岩溶滤作用、土壤来源与黄河侧向补给造成水中氟的富集;高锰地下水受到土壤组分影响广泛存在于研究区,而个别地区农业活动和地表水补给造成硝酸盐的点状污染.

关键词：豫北黄河下游浅层地下水 PCA-APCS-MLR 污染源解析原生劣质成因人为污染

Elastic scattering of ^(13)C and ^(14)C isotopes on a ^(208)Pb target at energies of approximately five times the Coulomb barriers

在线全文

学校读者我要写书评

暂无评论

Chinese Physics C 2024年第3期48卷 65-71页

作者：杨过段芳芳王康杨彦云孙志宇 Valdir Guimarães 庞丹阳陈文棣金磊许世伟马军兵马朋白真汪凌昊刘泉王惠仁吕冰锋郭松 Mukhi Kumar Raju 王秀华李荣华张玉虎周小红胡正国徐瑚珊 CAS Key Laboratory of High Precision Nuclear Spectroscopy Institute of Modern PhysicsChinese Academy of SciencesLanzhou 730000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100080China Instituto de Física Universidade de São PauloRua do Matão1371São Paulo 05508-090SPBrazil School of Physics and Beijing Key Laboratory of Advanced Nuclear Materials and Physics Beihang UniversityBeijing 100191China School of Physics Science and Engineering Tongji UniversityShanghai 200092China School of physics and Optoelectronic Engineering Anhui UniversityHefei 230601China Department of Physics GITAM School of ScienceGITAM UniversityVisakhapatnam 530045India

The elastic scattering angular distributions of ^(13)C at 340 MeV and ^(14)C at 294 MeV and 342 MeV on a ^(208)Pb target,which correspond to approximately five times the Coulomb barriers,were measured at the Radioactive Ion Beam line in *** data were analyzed within the optical model and continuum-discretized coupled-channels(CDCC)framework,and the results of both calculations could effectively account for the experimental *** differential cross sections of elastic scattering revealed no particular suppression at the Coulomb nuclear interference peak angles,suggesting that the breakup coupling effects on the elastic scattering angular distributions were negligibly small in this incident energy *** contributions from the couplings with inelastic states to the elastic cross sections were of minor importance within the angular range covered by these experiments.

关键词： elastic scattering radioactive ion beam angular distribution optical model coupling effects

双辊薄带连铸凝固过程中柱状晶向等轴晶转变的广义稳定性判据

在线全文

学校读者我要写书评

暂无评论

Transactions of Nonferrous Metals Society of China 2024年第5期34卷 1365-1379页

作者：吴盼胡佳琦张玉兵宋韶杰李勇王慧远袁国刘峰西北工业大学凝固技术国家重点实验室西安710072 东北大学轧制与自动化国家重点实验室沈阳110819 吉林大学超硬材料国家重点实验室长春130012 西北工业大学分析测试中心西安710072

为促进柱状晶向等轴晶转变(CET)获得均匀的等轴晶,大多数有效的理论聚焦于生长而忽略了形核的影响。为此,构建耦合细化剂异质形核和枝晶生长的理论框架,采用考虑双辊薄带连铸(VTC)凝固过程中热力学驱动力(?G)和动力学能垒(Q)的广义稳定... 详细信息

为促进柱状晶向等轴晶转变(CET)获得均匀的等轴晶,大多数有效的理论聚焦于生长而忽略了形核的影响。为此,构建耦合细化剂异质形核和枝晶生长的理论框架,采用考虑双辊薄带连铸(VTC)凝固过程中热力学驱动力(?G)和动力学能垒(Q)的广义稳定性(GS)新概念,研究CET位置、晶粒半径和力学性能。细化剂的加入,尤其是Al-5Ti-1B细化剂,通过增加形核的?G和生长的GS使晶粒半径细化到19μm,柱状枝晶的厚度增大到5~6 mm,同时提高强度和塑性。遵循高?G-高GS准则,细化剂直径优化为0.3μm。

关键词：广义稳定性细化剂柱状晶向等轴晶转变双辊薄带连铸