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Effect of Guanxin Danshen Dripping Pills on Coronary Heart Disease Comorbid with Depression or Anxiety: The ADECODE-Real World Study

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Chinese Journal of Integrative Medicine 2024年第5期30卷 443-448页

作者： WU Shi-hao SHI Wei-qi li Yu-hang liU Ru-hui HU Da-yi zheng li-qiang MA Wen-lin Department of Geriatric Medicine Tongji HospitalSchool of MedicineTongji UniversityShanghai 200065China Department of Cardiology Tongji HospitalSchool of MedicineTongji UniversityShanghai 200065China Department of Cardiology Peking University People's HospitalBeijing 100044China School of Public Health Shanghai Jiao Tong UniversityShanghai 200030China

Objective: To evaluate the efficacy of Guanxin Danshen Dripping Pill(GXDSDP) in treating anxiety and depression in patients with coronary heart disease(CHD). Methods: A total of 1,428 patients diagnosed with CHD screened for anxiety, depression, and quality of life(QOL) at baseline received 0.4 g of GXDSDP treatment 3 times per day and returned for monthly reassessment. Patients were recruited after stable treatment for CHD and received assessment of General Anxiety Disorder-7(GAD-7), Patient Health Questionnaire-9(PHQ-9), and Seattle Angina Questionnaire(SAQ) for evaluating anxiety, depression, and *** were followed up 3 times, once every 4 weeks, during outpatient visits for 12 weeks. Results: At the third follow-up(F3), the anxiety symptom of 63.79%(673/1,055) of the patients improved to sub-clinical level, and the GAD-7 score improved significantly(8.11 vs. 3.87, Plinical level, with a significant improvement in PHQ-9 score(8.69 vs. 4.41, Pline(all Plimitation(31.17 vs. 34.14), anginal stability(2.74 vs. 4.14), anginal frequency(8.16vs. 9.10), treatment satisfaction(13.43 vs. 16.29), and disease perception(8.69 vs. 11.02). Conclusions: A fixed dosage of GXDSDP may be a potential treatment option for CHD patients comorbid with anxiety or depression.(Registration No. ChiCTR2100051523)

关键词： Guanxin Danshen Dripping Pill coronary heart disease depression anxiety quality of life Chinese medicine

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一种应用于卫星中红外遥感的辐射传输简化计算方案

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红外与毫米波学报 2024年第3期43卷 375-390页

作者：姚前许华樊程李莉王思恒郑杨徐文斌侯伟真徐敬海庄齐枫周鹏张灏陈震霆李正强中国科学院空天信息创新研究院国家环境保护卫星遥感重点实验室北京100101 中国科学院大学北京100049 中国空间技术研究院遥感卫星总体部北京100094 北京环境特性研究所光学辐射重点实验室北京100854 南京工业大学测绘科学与技术学院江苏南京211816 昆明学院信息技术学院云南昆明650214

作为可见光-近红外和热红外的连接谱段,中红外(MIR)兼具短波辐射的反射特性和长波辐射的发射特性,对于温度探测、目标识别等应用场景有十分重要的意义。目前,MIR谱段辐射传输(RT)计算仍然面临背景参数输入多且不易获取的问题。基于此,... 详细信息

作为可见光-近红外和热红外的连接谱段,中红外(MIR)兼具短波辐射的反射特性和长波辐射的发射特性,对于温度探测、目标识别等应用场景有十分重要的意义。目前,MIR谱段辐射传输(RT)计算仍然面临背景参数输入多且不易获取的问题。基于此,提出了一种应用于卫星MIR遥感的RT简化计算方案。使用MODTRAN模型(MM),对MIR白天RT过程中所涉及的背景地表和大气参数定量模拟分析,得到影响RT的关键参数,据此形成一套基于MM的参数简化方案(SS)。在MODIS 6个MIR通道的中心波长处,对SS和MM计算的总辐亮度做对比验证,RMSE均小于0.004399,具有较高精度。SS仅依赖于表面温度、表面发射率、大气廓线类型、水汽和云光学厚度,不需要输入气溶胶、CO_(2)和O_(3)数据。相比MM,SS将输入参数从8类降低到5类,计算的时间效率提升了9.02%。在有限的计算资源下,本文所提的SS能够为MIR图像快速处理、大场景遥感仿真等应用领域提供支撑。

关键词：中红外(MIR)谱段辐射传输(RT)计算背景参数简化方案(SS)

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Rheological properties of wormlike micelles formed in the sodium oleate/trisodium phosphate aqueous solution

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Chinese Chemical Letters 2008年第4期19卷 483-487页

作者： Yong qiang Ji Wei Shan Wang Gan Zuo li li qiang zheng Key Laboratory of Colloid and Interface Chemistry Shandong UniversityMinistry of EducationJinan 250100China Shandong Institute of Supervision ＆ Inspection on Product Quality Jinan 250100China

Aqueous solution of anionic surfactant,sodium oleate（NaOA）,was studied by means of steady-state shear rheology and dynamic oscillatory *** system of NaOA/Na3PO4 showed high viscosity,strong viscoelasticity and good ability of countering Ca^2＋,Mg^2＋.The Maxwell model and Cole-Cole plot were applied to study the dynamic viscoelasticity of wormlike *** microstructures of the wormlike micelles were characterized by FF-TEM.

关键词： Wormlike micelles Rheology Sodium oleate Trisodium phosphate

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New type flooding systems in enhanced oil recovery

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Chinese Chemical Letters 2009年第10期20卷 1251-1254页

作者： Xin Ping li li Yu Yong qiang Ji Bo Wu Gan Zuo li li qiang zheng Key Laboratory of Colloid and Interfacial Chemistry of Ministry of Education in Shandong University Jinan Shandong 250100 China

Wormlike micelles, obtained in anionic surfactam sodium oleate （NaOA） solutions in the presence of sodium phosphate （Na3PO4）, were studied using the steady and dynamic rheological methods. The laboratory simulation flooding experiments were used to investigate the effects of flooding for the wormlike micelles system. The results show that the oil recovery is 32.7%. This flooding system is a new type and has high activity with a low cost.

关键词： Wormlike miceUes Rheology Oil recovery

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Bovine Serum Albumin Loaded Solid lipid Nanoparticles Prepared by Double Emulsion Method

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Chemical Research in Chinese Universities 2010年第1期26卷 136-141页

作者： li Zhen li Xin-wei zheng li-qiang liN Xiao-hong GENG Fei YU li Key Laboratory of Colloid and Interface Chemistry Ministry of Education Shandong University Jinan 250100 P. R. China

Solid lipid nanoparticles loaded with bovine serum albumin（BSA） were prepared by a double emulsion method. As the mass fraction of the model drug BSA increased from 0 to 15%, the particle size gradually increased. The physical stability of the nanoparticles was investigated by zeta potential measurement and they were shown to be quite stable. Fluorescence spectroscopy confirmed that the loaded position of BSA was on the interface between the inner aqueous phase and the solid lipid phase. Both Fourier-transform infrared spectroscopy and circular dichroism spectra indicate that BSA in the nanoparticles was not destroyed, but the secondary structure was disrupted slightly.

关键词： Solid lipid nanoparticle Double emulsion Bovine serum albumin Drug model

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Facile synthesis and characterization of uniform CdS colloidal spheres

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Chinese Chemical Letters 2012年第9期23卷 1091-1094页

作者： Xiu Jie Yang Xin Ping li Xiang Tao Bai li qiang zheng Key Laboratory of Colloid and Interface Chemistry of Ministry of Education Shandong UniversityChina Jinan 250100

Uniform CdS colloidal spheres have been successfully synthesized via a simple hydrothermal method. X-ray diffraction （XRD） analyses indicate that the products exhibit a hexagonal structure. Scanning electron （SEM） and transmission electron microscopy （TEM） are used to characterize CdS colloidal spheres. The final size of the spheres may be selected from a range of 71± 2 nm to approximately 181 ± 5 nm by changing the amount of polyvinylpyrrolidone （PVP） and hexamethylenetetramine （HMT）. The CdS colloidal spheres are not obtained in the absence of either of the capping agents. A synergistic effect between HMT and PVP is proposed to be crucial for the formation of colloidal spheres.

关键词： Microstructure Nanomaterials CdS Colloidal spheres Hydrothermal synthesis

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Ionic liquid-assisted synthesis of silver nanorods by polyol reduction

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Chinese Chemical Letters 2010年第7期21卷 872-875页

作者： Hong Ying Wang Yan An Gao Ming Wei Zhao li qiang zheng Key Laboratory of Colloid and Interface Chemistry of Ministry of Education in Shandong University Jinan 250100China

Silver nanorods have been successfully synthesized in large scale by the ethylene glycol（EG） reduction in the presence of ionic liquid（IL） 1-butyl-3-methylimidazolium tetrafluoroborate（bmimBF_4） and polyvinyl-pyrrolidone（PVP）.The silver nanorods were characterized by scanning electron microscopy（SEM）,high-resolution transmission electron microscopy（HRTEM）,transmission electron microscopy（TEM）,electron energy disperse spectroscopy（EDS） and UV-vis *** results showed that the uniform silver nanorods have an average diameter of about 100 nm and the aspect ratio from 15 to ***,bmimBF_4 may play a role of capping agent together with PVP in the formation of silver *** the other band,bmimBF_4 may accelerate nucleation and improve the stability of the resulting Ag nanorods due to the low interface tension of IL.

关键词： Silver nanorods Ionic liquid Ethylene glycol Capping agent

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Effects of Siqi Decoction on Concentration of Nitric Oxide and Activity of Nitric Oxide Synthase in Blood Serum of Rats with Myocardial Ischemia

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Chemical Research in Chinese Universities 2008年第1期24卷 65-68页

作者： SU Yan-bin li zheng-qiang SU Yan-wen ZHANG Fen-rong School of Chemical and Pharmaceutical Engineering Jilin Institute of Chemical Technology Jilin 132022 P. R. China Key Laboratory of Molecular Etymology and Engineering Ministry of Education Jilin University Changchun 130021 P. R. China Jilin Provincial Institute for Drug and Food Control Changchun 130033 P. R. China

To study the effects of Siqi decoction on rats with Myocardial Ischemia, the model of Myocardium Ischemia was made for the Wistar rats cured with posterior pituitary injection through vein in tail. Siqi decoction, Diaoxinxuekang（DK） and Fufangdanshenpian（FD）, the latter two drugs of which were effective TCM drugs of anti-Myocardial Ischemia at present, were administrated to the rats with Myocardium Ischemia for 5 days to compare the effect of anti-Myocardium Ischemia as reference drugs by measuring the changes of NO concentration and activity of NOS in the rat blood serum with Myocardial Ischemia. There was a remarkable increase in the NO concentration and activity of NOS in serum in Siqi decoction groups compared with those in control group（p〈0.05）. The results of the prevention group in experiment of Siqi decoction are better than those of the cure group. Siqi decoction was really fit for Myocardium Ischemia via increasing NO concentration by stimulating the activity of NOS in serum. The effect of Siqi decoction against Myocardium Ischemia in preventive group is better than the curative that of Siqi decoction in the curative group.

关键词： Siqi decoction Myocardial Ischemia Posterior pituitary Nitric oxide(NO) Nitric oxide synthase(NOS)

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Studies on HEPES Stabilizing M Intermediate of Bacteriorhodopsin

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Chemical Research in Chinese Universities 1995年第3期11卷 215-218页

作者： Fu, Xue-qi li, zheng-qiang Wang, Jin-dui Wang, Bao-hui li, Bo-fu li, Tie-jin JIliN UNIV NATL KEY LAB ENZYME ENGNCHANGCHUN 130023PEOPLES R CHINA JIliN UNIV KEY LAB MOLEC SPECTRUM & MOLEC STRUCTCHANGCHUN 130023PEOPLES R CHINA JIliN UNIV DEPT CHEMCHANGCHUN 130023PEOPLES R CHINA

EPES has proved to stabilize M intermediate of Bacteriorhodopsin. Absorp-tion and Raman spectra showed that there was a more stable form of M intermedi-ate in BR-HEPES solution. It was found by SPS that there were two... 详细信息

关键词： Bacteriorhodopsin M intermediate HEPES

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Exploring Trade-offs in Thermal Interface Materials:The Impact of Polymer-Filler Interfaces on Thermal Conductivity and Thixotropy

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Chinese Journal of Polymer Science 2024年第7期42卷 916-925,I0006页

作者： Bin Zhang zheng-li Dou Yong-zheng Zhang qiang Fu Kai Wu College of Polymer Science and Engineering State Key Laboratory of Polymer Materials EngineeringSichuan UniversityChengdu610065China

Effective thermal transport across solid-solid interfaces which is essential in thermal interface materials(TIMs),necessitates both optimal thixotropy and high thermal *** role of filler surface modification,a fundamental aspect of TIM fabrication,in the influence of these properties is not fully *** study employs the use of a silane coupling agent(SCA)to modify alumina,integrating experimental approaches with molecular dynamics simulations,to elucidate the interface effects on thixotropy and thermal conductivity in polydimethylsiloxane(PDMS)-based *** findings reveal that the variations of SCAs modify both interface binding energy and transition layer *** interface binding energy restricts macromolecular segmental relaxation near the interface,hindering desirable thixotropy and bond line *** the contrary,the thickness of the transition layer at the interface positively influences thermal conductivity,facilitating the transport of phonons between the polymer and ***,selecting an optimal SCA allows a balance between traditionally conflicting goals of high thermal conductivity and minimal bond line thickness,achieving an impressively low interface thermal resistance of just 2.45-4.29 K·mm^(2)·W^(-1)at275.8 kPa.

关键词： Thermal interface material Surface modification Thermal conductivity Thixotropy Interface thermal resistance

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