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可弯曲负压吸引鞘联合一次性输尿管软镜治疗上尿路结石的应用

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中国医疗器械信息 2024年第11期30卷 148-150页

作者：杨声增王泳许文杰李永斌建瓯市立医院泌尿外科福建南平353199

目的:探讨弯曲负压吸引鞘联合一次性输尿管软镜(su-fURS)治疗上尿路结石的效果。方法:选取2022年8月~2023年8月上尿路结石患者100例。随机数字表法分为两组,包括对照组(常规鞘联合su-fURS治疗)与观察组(可弯曲负压吸引鞘联合su-fURS治... 详细信息

目的:探讨弯曲负压吸引鞘联合一次性输尿管软镜(su-fURS)治疗上尿路结石的效果。方法:选取2022年8月~2023年8月上尿路结石患者100例。随机数字表法分为两组,包括对照组(常规鞘联合su-fURS治疗)与观察组(可弯曲负压吸引鞘联合su-fURS治疗),每组50例,对比效果。结果:对照组和观察组患者的住院时间、术中出血量相比差异不显著(P>0.05),观察组手术时间比对照组高(P0.05)。结论:上尿路结石应用可弯曲负压吸引鞘联合su-fURS治疗,与常规鞘联合su-fURS治疗比较,虽然会增加手术时间,导致血红蛋白下降值提升,但是却可以明显减少住院费用,避免或减少辅助体外冲击波碎石治疗,促进并发症发生率下降,同时提高结石清除率。

关键词：上尿路结石一次性输尿管软镜可弯曲负压吸引鞘结石清除率安全性

带电抢修机器人液压柔性关节多机械臂协同控制

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液压气动与密封 2024年第10期44卷 49-54页

作者：姜龙云高永强王文成柴立华李永彬国网山东省电力公司东营供电公司山东东营257000

液压柔性关节多机械臂是一种利用液压系统控制的多段柔性结构机械臂,当电力系统同时出现多处故障时,就需要带电抢修机器人的液压柔性关节多机械臂完成协调控制。而多机械臂在协作完成抢修任务的过程中,多机械臂的操作空间存在相互重叠部... 详细信息

液压柔性关节多机械臂是一种利用液压系统控制的多段柔性结构机械臂,当电力系统同时出现多处故障时,就需要带电抢修机器人的液压柔性关节多机械臂完成协调控制。而多机械臂在协作完成抢修任务的过程中,多机械臂的操作空间存在相互重叠部分,影响抢修任务的工作效果,为此,提出一种带电抢修机器人液压柔性关节多机械臂协同控制方法。基于机器人液压柔性机械臂协同控制结构,确定机器人多机械臂的基础控制参数,构建用于提取示教轨迹特征的高斯混合模型,并计算模型重要参数,将示教轨迹特征提取结果与滑模控制原理结合在一起,以李雅普诺夫全局稳定性定理为依据,使机械臂系统整体处于稳定状态,实现液压柔性关节多机械臂的协调控制。实验测试结果表明,所提方法可以控制机器人的4个机械臂按照示教轨迹和预先设定好的速度协同运行,各个机械臂之间互不干扰,共同完成带电抢修任务。

关键词：带电抢修机器人液压柔性关节多机械臂协同控制

Effect of Al_(2)O_(3)fiber on twin intersections-induced dynamic recrystallization in fine-grained TiAl matrix composite

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Journal of Materials Science & Technology 2024年第5期172卷 1-14页

作者： Yaofeng Luo Yan Wang li Wang bin liu yong liu State Key Laboratory of Powder Metallurgy Central South UniversityChangsha 410083China

Dynamic recrystallization(DRX)is of great significance for the thermomechanical processing and microstructural regulation of TiAl ***,the underlying DRX mechanism remains poorly *** this study,an Avrami kinetics model for DRX was established,which was capable of predicting the DRX fraction *** addition,the effect of Al_(2)O_(3)short fiber on the DRX mechanisms of TiAl matrix composite during the isothermal compression was investigated for the first *** re-sults showed that other than inhibiting DRX by particles in the TiAl matrix composites,the addition of Al_(2)O_(3)short fiber accelerated a novel DRX process,which was induced by twinning and twin intersec-tions(TDRX).Thus,this composite exhibited a higher DRX rate than that of the as-cast TiAl monolithic *** origin of the twin intersection and TDRX for the composite was *** stress concentration near the Al_(2)O_(3)fiber was above the critical shear stress for twinning and thus was favorable for the formation of twinning and twin *** high stored strain energy at the regions of twins and twin intersections provided the driving force for *** accelerated the grain refinement in the TiAl matrix near the Al_(2)O_(3)*** present findings would provide a new perspective on DRX mechanisms,and provide the scientific guidance for optimizing the microstructures of TiAl matrix composites.

关键词： TiAl matrix composite Al_(2)O_(3)fiber Twin intersection Dynamic recrystallization

Urea-induced interfacial engineering enabling highly reversible aqueous zinc-ion battery

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Rare Metals 2024年第4期43卷 1599-1609页

作者： bin-Rui Xu Quan-An li yong liu Guang-bin Wang Zi-He Zhang Feng-Zhang Ren School of Material Science and Engineering Henan University of Science and TechnologyLuoyang471023China School of Information Engineering Henan University of Science and TechnologyLuoyang471023China Longmen Laboratory Luoyang471023China Provincial and Ministerial Co-Construction of Collaborative Innovation Center for Non-Ferrous Metal New Materials and Advanced Processing Technology Luoyang471023China

Aqueous zinc-ion batteries(AZIBs)have been regarded as prospective rechargeable energy storage devices because of the high theoretical capacity and low redox potential of Zn ***,the uncontrollable formation of dendrites and the water-induced side reactions at the Zn/electrolyte interface,and the poor reversibility under a high current density(>2 mA·cm^(-2))and large area capacity(>2 mAh·cm^(-2))still limit the practical applications of ***,a strategy that can overcome these difficulties is urgently ***,we introduce an environmentally friendly and low-cost additive,namely urea,to the electrolyte of AZIBs to induce uniform Zn deposition and suppress the side *** of the adsorption behavior,electrochemical characterization,and observations of the morphology revealed the interfacial modification induced by urea on the Zn/electrolyte interface,demonstrating its huge potential in ***,the long-term cycling stability(over2100 h)of a Zn/Zn symmetric cell under a high current density of 5 mA·cm^(-2)and a capacity of 5 mAh·cm^(-2)was achieved with a 1 mol·L^(-1)ZnSO_(4)electrolyte with the urea ***,the assembled Zn/NH_4V_4O_(10)full cell with urea exhibited excellent cycling performance and an outstanding average Coulombic efficiency of 99.98%.These results indicate that this is a low-cost and effective additive strategy for realizing highly reversible AZIBs.

关键词： Zn anode Urea additive Interface engineering Dendrite growth Side reaction

Exploring Trade-offs in Thermal Interface Materials:The Impact of Polymer-Filler Interfaces on Thermal Conductivity and Thixotropy

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Chinese Journal of Polymer Science 2024年第7期42卷 916-925,I0006页

作者： bin Zhang Zheng-li Dou yong-Zheng Zhang Qiang Fu Kai Wu College of Polymer Science and Engineering State Key Laboratory of Polymer Materials EngineeringSichuan UniversityChengdu610065China

Effective thermal transport across solid-solid interfaces which is essential in thermal interface materials(TIMs),necessitates both optimal thixotropy and high thermal *** role of filler surface modification,a fundamental aspect of TIM fabrication,in the influence of these properties is not fully *** study employs the use of a silane coupling agent(SCA)to modify alumina,integrating experimental approaches with molecular dynamics simulations,to elucidate the interface effects on thixotropy and thermal conductivity in polydimethylsiloxane(PDMS)-based *** findings reveal that the variations of SCAs modify both interface binding energy and transition layer *** interface binding energy restricts macromolecular segmental relaxation near the interface,hindering desirable thixotropy and bond line *** the contrary,the thickness of the transition layer at the interface positively influences thermal conductivity,facilitating the transport of phonons between the polymer and ***,selecting an optimal SCA allows a balance between traditionally conflicting goals of high thermal conductivity and minimal bond line thickness,achieving an impressively low interface thermal resistance of just 2.45-4.29 K·mm^(2)·W^(-1)at275.8 kPa.

关键词： Thermal interface material Surface modification Thermal conductivity Thixotropy Interface thermal resistance

Oil-soluble polymer brushes-functionalized nanoMOFs for highly efficient friction and wear reduction

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Friction 2024年第7期12卷 1499-1511页

作者： Jianxi liU yong QIAN Dongsheng li Wei WU Mengchen ZHANG Jie YAN bin li Feng ZHOU State Key Laboratory of Solidification Processing Center of Advanced Lubrication and Seal MaterialsSchool of Materials Science and EngineeringNorthwestern Polytechnical UniversityXi'an 710072China Shaanxi Engineering Research Center of Special Sealing Technology Xi'an Aerospace Propulsion InstituteXi'an 710100China State Key Laboratory of Solid Lubrication Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou 730000China

Nanomaterials as lubricating oil additives have attracted significant attention because of their designable composition and structure,suitable mechanical property,and tunable surface ***,the poor compatibility between nanomaterials and base oil limits their further *** this work,we demonstrated oil-soluble poly(lauryl methacrylate)(PLMA)brushes-grafted metal-organic frameworks nanoparticles(nanoMOFs)as lubricating oil additives that can achieve efficient friction reduction and anti-wear *** were synthesized by free-radical polymerization,which was coordinatively grafted onto the surface of the UiO-67 ***,PLMA brushes were grown on the macroinitiator-modified UiO-67 by surface-initiated atom transfer radical polymerization,which greatly improved the lipophilic property of the UiO-67 nanoparticles and significantly enhanced the colloidal stability and long-term dispersity in both non-polar solvent and base *** adding UiO-67@PLMA nanoparticles into the 500 SN base oil,coefficient of friction and wear volume reductions of 45.3%and 75.5%were achieved due to their excellent mechanical properties and oil ***,the load-carrying capacity of 500 SN was greatly increased from 100 to 500 N by the UiO-67@PLMA additives,and their excellent tribological performance was demonstrated even at a high friction frequency of 65 Hz and high temperature of 120℃.Our work highlights oil-soluble polymer brushes-functionalized nanoMOFs for highly efficient lubricating additives.

关键词： MOFs polymer brushes surface modification tribological properties friction reduction anti-wear

Oyster Protein Hydrolysate Alleviates Cadmium Toxicity by Restoring Cadmium-Induced Intestinal Damage and Gut Microbiota Dysbiosis in Mice via Its Abundance of Methionine,Tyrosine,and Glutamine

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Biomedical and Environmental Sciences 2022年第7期35卷 669-673页

作者： WANG Jing Wen FANG Zhi Jia li yong bin HUANG lin Ru SUN li Jun liU Ying WANG Ya ling liAO Jian Meng College of Food Science and Technology Guangdong Provincial Key Laboratory of Aquatic Product Processing and SafetyGuangdong Provincial Engineering Technology Research Center of Marine FoodKey Laboratory of Advanced Processing of Aquatic Products of Guangdong Higher Education InstitutionGuangdong Ocean UniversityZhanjiang 524088GuangdongChina Institute for Food and Drug Control Zhanjiang 524088GuangdongChina

As a typical heavy metal contaminant in food,cadmium(Cd)easily enters the human food chain via crop production,and therefore,threatens human health[1].Intestinal absorption is the principal route for Cd entry into the body,and therefore,intestinal tissue become the primary target for Cd toxicity[2].Previous studies showed that acute Cd exposure damaged intestinal tight junctions,resulting in gut barrier destruction and alterations in gut microbiota[3].Thus,the effective prevention of Cd-induced intestinal damage has become a major research challenge.

关键词： prevention alterations cadmium

Transglutaminase 2 serves as a pathogenic hub gene of KRAS mutant colon cancer based on integrated analysis

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 2074-2090页

作者： Wei-bin Peng Yu-Ping li yong Zeng Kai Chen First People’s Hospital of Foshan Foshan 528000Guangdong ProvinceChina Department of Radiation Oncology Cancer Hospital of Shantou University Medical CollegeShantou 515031Guangdong ProvinceChina

BACKGROUND Colon cancer is acknowledged as one of the most common malignancies worldwide,ranking third in United States regarding incidence and ***,approximately 40%of colon cancer cases harbor oncogenic KRAS mutations,resulting in the continuous activation of epidermal growth factor receptor *** To investigate the key pathogenic genes in KRAS mutant colon cancer holds considerable *** Weighted gene co-expression network analysis,in combination with additional bioinformatics analysis,were conducted to screen the key factors driving the progression of KRAS mutant colon ***,various in vitro experiments were also conducted to explore the biological function of transglutaminase 2(TGM2).RESULTS Integrated analysis demonstrated that TGM2 acted as an independent prognostic factor for progression-free *** analysis on tissue microarrays revealed that TGM2 was associated with an elevated probability of perineural invasion in patients with KRAS mutant colon ***,biological roles of the key gene TGM2 was also assessed,suggesting that the downregulation of TGM2 attenuated the proliferation,invasion,and migration of the KRAS mutant colon cancer cell *** This study underscores the potential significance of TGM2 in the progression of KRAS mutant colon *** insight not only offers a theoretical foundation for therapeutic approaches but also highlights the need for additional clinical trials and fundamental research to support our preliminary findings.

关键词： Colon cancer KRAS mutation Transglutaminase 2 Weighted gene co-expression network analysis

Microstructure and room temperature fracture toughness of Nb-Si-based alloys with Sr addition

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Rare Metals 2024年第8期43卷 3904-3912页

作者： yong-lin Huang li-Na Jia bin Kong Yue-ling Guo Na Wang School of Materials Science and Engineering Beihang UniversityBeijing 100191China

Nb-Si-based alloys show great potential to surpass the widely used Ni-based *** element Sr is widely applied in aluminum and magnesium alloys,but reports about the effects of Sr on Nb-Si-based alloys are quite ***,Nb-Si-based alloys with nominal compositions of Nb-15Si-24Ti-4Cr-2Al-2Hf-0/0.05/0.15Sr(at%)were prepared by directional solidification and heat *** microstructural characterization and room temperature fracture toughness of Nb-Si-based alloy were systematically *** show that all these alloys consist of Nb_5Si_3 phase embedded within Nb solid solution(Nb_(ss)) *** Nb_(5)Si_(3) phase becomes refined and more discontinuous after adding minor *** for the fracture toughness,0.05 at% and 0.15 at% Sr additions do not cause significant *** discontinuous and refining mechanism of Sr element was studied,and the analysis of toughness decreasing with Sr addition reveals that the size of Nb_(ss) phase plays a crucial role in determining the fracture toughness.

关键词： Nb-Si alloy Refinement Discontinuous Fracture toughness Nb_(ss)