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Oyster Protein Hydrolysate Alleviates Cadmium Toxicity by Restoring Cadmium-Induced Intestinal Damage and Gut Microbiota Dysbiosis in Mice via Its Abundance of Methionine,Tyrosine,and Glutamine

Oyster Protein Hydrolysate Alleviates Cadmium Toxicity by Restoring Cadmium-Induced Intestinal Damage and Gut Microbiota Dysbiosis in Mice via Its Abundance of Methionine, Tyrosine, and Glutamine

作     者:WANG Jing Wen FANG Zhi Jia LI Yong Bin HUANG Lin Ru SUN Li Jun LIU Ying WANG Ya Ling LIAO Jian Meng WANG Jing Wen;FANG Zhi Jia;LI Yong Bin;HUANG Lin Ru;SUN Li Jun;LIU Ying;WANG Ya Ling;LIAO Jian Meng

作者机构:College of Food Science and TechnologyGuangdong Provincial Key Laboratory of Aquatic Product Processing and SafetyGuangdong Provincial Engineering Technology Research Center of Marine FoodKey Laboratory of Advanced Processing of Aquatic Products of Guangdong Higher Education InstitutionGuangdong Ocean UniversityZhanjiang 524088GuangdongChina Institute for Food and Drug ControlZhanjiang 524088GuangdongChina 

出 版 物:《Biomedical and Environmental Sciences》 (生物医学与环境科学(英文版))

年 卷 期:2022年第35卷第7期

页      面:669-673页

核心收录:

学科分类:0832[工学-食品科学与工程(可授工学、农学学位)] 08[工学] 083204[工学-水产品加工及贮藏工程] 

基  金:supported by the National Natural Science Foundation of China [No. 32172215 and 31701706] the Program for Scientific Research Start-up Funds of the Guangdong Ocean University [No. R17102] Characteristic Innovation Project of Guangdong Province [No. 2018KTSCX089] Guangdong Basic and Applied Basic Research Foundation [No.2019A1515010809, 2021A1515012443] 

主  题:prevention alterations cadmium 

摘      要:As a typical heavy metal contaminant in food,cadmium(Cd)easily enters the human food chain via crop production,and therefore,threatens human health[1].Intestinal absorption is the principal route for Cd entry into the body,and therefore,intestinal tissue become the primary target for Cd toxicity[2].Previous studies showed that acute Cd exposure damaged intestinal tight junctions,resulting in gut barrier destruction and alterations in gut microbiota[3].Thus,the effective prevention of Cd-induced intestinal damage has become a major research challenge.

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