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A robust TDOA-based location method and its performance analysis

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Science in China(Series F) 2009年第5期52卷 876-882页

作者： li WanChun wei ping XIAO XianCi School of Electronic Engineering University of Electronic Science and Technology of China Chengdu 610054 China

Based on time difference of arrive （TDOA）, the regularized constrained total least square （RCTLS） algorithm for passive location is presented in this paper. RCLTS is used to solve the location equations by transforming the nonlinear equations about TDOA into linear equations about parameters of the position and range and expanding the true TDOA in a first-order Taylor series about measurement TDOA. A proper weight is chosen by the least mean square error （MSE） rule to obtain the location solution through analyzing the location error, whose feasibility and effectiveness are well proved by computer simulations. The CRB and GDOP for TDOA-based location are given.

关键词： TDOA-based location RCTLS performance analysis

Synthesis of Multiester-appended and Multicarboxylic-appended Imidazolium Ionic liquids

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Chinese Chemical Letters 2006年第2期17卷 169-172页

作者： wei Guo GENG Xuc Hui li Le Fu WANG Hong li DUAN wei ping PAN Department of Chemical Engineering School of Chemical and Energy Engineering South China University of Technology Guangzhou 510640

Multiester-appended imidazolium ionic liquids were synthesized in a quatemization reaction between the imidazole derivatives carrying single or double esters and ethyl chloroacetate or bromoethane. Multicarboxylic-appended imidazolium ionic liquids were achieved from the hydrolysis of the corresponding ionic liquids. The influences of multifunctional groups on the transition temperatures and viscosity of these new ionic liquids were investigated.

关键词： Ionic liquid multiester group multicarboxylic group synthesis

Properties of Parabolic linear Bound Potential and Coulomb Bound Potential Quantum Dot Qubit

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Communications in Theoretical Physics 2008年第2期49卷 311-314页

作者： WANG Zi-Wu li wei-ping YIN Ji-Wen XIAO Jing-lin Department of Physics and Electron Information Engineering Inner Mongolia Chifeng College Chifeng 024000 China Department of Physics and Electromechanics Inner Mongolia Nationality University Tongliao 028043 China

On the condition of electric-LO phonon strong-coupling in a parabolic quantum dot, we obtain the eigenenergy of the ground-state and the first-excited state, the eigenfunctions of the ground-state and the first-excited state by using variational method of Pekar type. This system in quantum dot may be employed as a two-level quantum system-qubit. When the electron is in the superposition state of the ground- and the first-excited state, we obtain the time evolution of the electron density. The relation of the probability density of electron on the Coulomb binding parameter and the relations of the period of oscillation on the Coulomb binding parameter, the electron-LO-phonon coupling constant and the confinement length are derived.

关键词： quantum dot quantum information qubit decoherece

Combining Adaptive Diffusion with Difference for Detecting Nonstationary Signals

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自动化学报 2007年第9期33卷 931-935页

作者： TAN Xiao-Gang li li-ping wei ping School of Electronic Engineering University of Electronic Science and Technology of China （UESTC） Chengdu 610054 P.R. China

时间频率分析试图构造时间和频率的密度功能与时间在要分析的信号和信号的频率的进化揭示频率部件。Wigner 分发(WD ) 是为在雷达的域里分析 nonstationary 信号的最基本、广泛地使用的方法之一，通讯，等等。然而， WD 的申请被干扰术... 详细信息

时间频率分析试图构造时间和频率的密度功能与时间在要分析的信号和信号的频率的进化揭示频率部件。Wigner 分发(WD ) 是为在雷达的域里分析 nonstationary 信号的最基本、广泛地使用的方法之一，通讯，等等。然而， WD 的申请被干扰术语的存在极大地限制。适应散开方法建议由朱利恩·戈斯梅，移开 WD 的干扰术语等。是面对信号产生的干扰术语无效，其分布在 WD 的时间频率飞机一起被交织。我们为移开这些干扰术语为检测 nonstationary 信号改进科恩类的时间频率表示的分辨率和可读性把散开技术与差别方法相结合。

关键词：适应性扩散不稳定信号探测干涉项

Synergistic effect of oxymatrine and angiogenesis inhibitor NM-3 on modulating apoptosis in human gastric cancer cells

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World Journal of Gastroenterology 2007年第12期13卷 1788-1793页

作者： Ming-Quan Song Jin-Shui Zhu Jin-lian Chen Long Wang wei Da li Zhu wei-ping Zhang Department of Gastroenterology The Sixth Affiliated Hospital of Shanghai Jiaotong University Shanghai 200233 China

AIM: To investigate the synergistic effect of oxymatrine(OM) and angiogenesis inhibitor NM-3 on modulatingapoptosis in human gastric cancer cell lines SGC-7901,MKN-45, MKN-74. METHODS: Human gastric cancer lines SGC-7901,MKN-45, MKN-74 were treated with OM in the absenceand presence of NM-3. The inhibitory rates weredetected by MTT assay. Synergistic effect of OM andNM-3 on the growth of survivin, bcl-2, bax and p53 inSGC-7901 cells were examined by semiquantitative RT-PCR and Western blotting, and their growth inhibitoryeffects were also observed on SGC-7901 tumor xenograftin nude ***: OM combined with NM-3 exhibited asynergistic inhibitory effect on the growth of SGC-7901,MKN-45 and MKN-74 cells in a time-dependent ***-four hours after treatment with OM, NM-3 aloneand their combination, mRNA expression of survivin andbcl-2 in SGC-7901 cells decreased, p53 mRNA expressionincreased. OM (4 g/L) combined with NM-3 significantlyincreased the expression of p53 mRNA and decreasedthe expression of survivin and bcl-2 compared witheither agent alone (193% ± 34% vs 129% ± 12%;44% ± 18% vs 92% ± 18%; 36 ± 17% vs 93% ± 23%,P < 0.05). Western blotting showed that the synergisticeffect of OM and NM-3 on protein translation of survivin,bcl-2 and p 53 was in accordance with their ***, OM/NM-3 combination obviously exhibitedantitumor growth effect in xenografted human gastriccancer cells SGC-7901 compared with either agent ***: OM combined with NM-3 has synergisticinhibitory effects on human gastric cancer cells in vitro and can suppress the growth of xenografted human gastric cancer cells SGC-7901 in vivo.

关键词： NM-3 compound Oxymatrine Gastric cancer Apoptosis

Respiratory face mask:a novel and cost-effective device for use during the application of myocardial ischemia in rats

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2009年第5期10卷 391-394页

作者： Yuan YUAN Fei li Yue-min WANG Rong-qing ZHANG li-ping wei Hai-chang WANG Department of Cardiology Xijing Hospital the Fourth Military Medical University Xi 'an 710032 China Department of Physiology the Fourth Military Medical University Xi 'an 710032 China

To shorten operation time and improve survival rate of rats with myocardial ischemia or myocardial infarction,we use a novel device comprised of a face mask and a head/neck retainer in this *** report the basic design of the novel respiratory face mask(RFM) and evaluate its performance in a rat model of myocardial *** device is cost-effective and easier to handle than other devices,such as tracheal *** with conventional tracheal intubation,we found that RFM shortens operation time significantly while keeping blood indices normal;the mean operation time for rats in the mask group was(32±3) min,and that for the intubation group was(45±7) min(Pweight of *** conclusion,RFM is an appropriate device for the establishment of myocardial infarction or ischemia-reperfusion in rats.

关键词： Rats Respiratory face mask (RFM) Myocardial ischemia Myocardial infarction

Asymmetric synthesis of pedamide using I_2-induced heterocyclization to construct the skeleton

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Chinese Chemical Letters 2009年第7期20卷 775-778页

作者： De Gang liu Ji Jun Xue Zhi Xiang Xie li ping wei Hua Bing Zhang Ying li State Key Laboratory of Applied Organic Chemistry Lanzhou University Lanzhou 730000 PR China

An alternative approach to synthesize pedamide, a key building block of pederin was described. Iodine-induced asymmetric heterocyclization was used as the key step to construct the skeleton, a tetrahydropyran ring with three chiral centers. Brown＇s asymmetric allylation and Lewis acid-mediated allylation were investigated to introduce chains and chiral alcohols. Sharpless dihydroxylation decorated the side chain. And high optically pure target was obtained by removing the epimers formed in these reactions on column chromatography.C2009 Ji Jun Xue. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All fights reserved.

关键词： Synthesis Pedamide Pederin

Quality Control and Analysis of Global Gauge-Based Daily Precipitation Dataset from 1980 to 2009

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Advances in Climate Change Research 2012年第1期3卷 45-53页

作者： NIE Su-ping LUO Yong li wei-ping WU Tong-Wen SHI Xue-li WANG Zai-Zhi Laboratory for Climate Studies National Climate CenterChina Meteorological AdministrationBeijing 100081China

A series of quality control(QC) procedures were performed on a gauge-based global daily precipitation dataset from the Global Telecommunication System(GTS) for the period 1980-2009.A new global daily precipitation(NGDP) dataset was constructed by applying those QC procedures to eliminate erroneous *** NGDP dataset was evaluated using the NOAA Climate Prediction Center Merged Analysis of Precipitation(CMAP) and the Global Precipitation Climatology Project(GPCP) precipitation *** results showed that the frequency distribution and spatial distribution pattern of NGDP had a nice match with those from the CMAP and GPCP *** global mean correlation coefficients with the CMAP and GPCP data increased from 0.24 for original GTS precipitation data to about 0.70 for NGDP ***,the root mean square errors(RMSE) decreased from 12 mm per day to 1 mm per *** interannual variabilities of NGDP monthly precipitation are consistent with the CMAP and GPCP datasets in ***,the seasonal variabilities for most land areas on the Earth of NGDP dataset are also consistent with the CMAP and GPCP precipitation products.

关键词： global surface weather report data GTS data daily precipitation quality control

Construction of hpaA gene from a clinical isolate of Helicobacter pyloriand identification of fusion protein

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World Journal of Gastroenterology 2003年第7期9卷 1529-1536页

作者： Ya-Fei Mao Jie Yan li-wei li Shu-ping li Department of Medical Microbiology and Parasitology,College of Medical Sciences,Zhejiang University,Hangzhou 310031,Zhejiang Province,China Department of Medical Microbiology and Parasitology College of Medical Sciences Zhejiang University Hangzhou 310031 Zhejiang Province China.

AIM: To clone hpaA gene from a clinical strain of Helicobacter pylori and to construct the expression vector of the gene and to identify immunity of the fusion ***: The hpaA gene from a clinical isolate Y06 of *** was amplified by high fidelity PCR. The nucleotide sequence of the target DNA amplification fragment was sequenced after T-A cloning. The recombinant expression vector inserted with hpaA gene was constructed. The expression of HpaA fusion protein in E. coli BL21DE3 induced by IPTG at different dosages was examined by *** blot with commercial antibody against whole cell of H. pylorias well as immunodiffusion assay with selfprepared rabbit antiserum against HpaA fusion protein were applied to determine immunity of the fusion protein. EliSA was used to detect the antibody against HpaA in sera of 125 patients infected with H. pylori and to examine HpaA expression of 109 clinical isolates of H. ***: In comparison with the reported corresponding sequences, the homologies of nucleotide and putative amino acid sequences of the cloned hpaA gene were from 94.25-97.32 % and 95.38-98.46 %, respectively. The output of HpaA fusion protein in its expression system of pET32ahpaA-BL21DE3 was approximately 40 % of the total bacterial proteins. HpaA fusion protein was able to combine with the commercial antibody against whole cell of H. pyloriand to induce rabbit producing specific antiserum with 1:4immunodiffusion titer after the animal was immunized with the fusion protein. 81.6 % of the serum samples from 125patients infected with ***(102/125) were positive for HpaA antibody and all of the tested isolates of ***(109/109) were detectable for ***: A prokaryotic expression system with high efficiency of *** gene was successfully *** HpaA expressing fusion protein showed satisfactory immunoreactivity and antigenicity. High frequencies of HpaA expression in different H. pyloriclinicalstrains an

关键词： hpaA基因幽门螺旋杆菌融合蛋白聚合酶链反应