Respiratory face mask:a novel and cost-effective device for use during the application of myocardial ischemia in rats

作     者：Yuan YUAN Fei LI Yue-min WANG Rong-qing ZHANG Li-ping WEI Hai-chang WANG 

作者机构：Department of Cardiology Xijing Hospital the Fourth Military Medical University Xi 'an 710032 China Department of Physiology the Fourth Military Medical University Xi 'an 710032 China 

出 版 物：《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 (浙江大学学报（英文版）B辑（生物医学与生物技术）)

年 卷 期：2009年第10卷第5期

页      面：391-394页

核心收录：

学科分类：090603[农学-临床兽医学] 0710[理学-生物学] 07[理学] 09[农学] 0906[农学-兽医学] 071003[理学-生理学] 

基　　金：(No.30600580) supported by the National Natural Science Foundation of China 

主　　题：Rats Respiratory face mask (RFM) Myocardial ischemia Myocardial infarction 

摘      要：To shorten operation time and improve survival rate of rats with myocardial ischemia or myocardial infarction,we use a novel device comprised of a face mask and a head/neck retainer in this *** report the basic design of the novel respiratory face mask(RFM) and evaluate its performance in a rat model of myocardial *** device is cost-effective and easier to handle than other devices,such as tracheal *** with conventional tracheal intubation,we found that RFM shortens operation time significantly while keeping blood indices normal;the mean operation time for rats in the mask group was(32±3) min,and that for the intubation group was(45±7) min(P0.05).Moreover,the size and shape of the RFM can be changed according to the body weight of *** conclusion,RFM is an appropriate device for the establishment of myocardial infarction or ischemia-reperfusion in rats.