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Bonding Interface Imaging and Shear Strength Prediction by Ultrasound1

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Chinese Physics Letters 2010年第6期27卷 118-121页

作者： li Yong-An MAO Jie li ming-xuan WANG Xiao-Min AN Zhi-Wu ZHUANG Qiao State Key Laboratory of Acoustics Institute of Acoustics Chinese Academy of Sciences Beijing 100190

The propagation of a longitudinal ultrasonic wave normally incident upon an adhesively bonded structure is stud- ied. The structure consists of adherend and adhesive layers with finite thickness. Interfaces between adherend and adhesive are regarded as distributed springs. Theoretical and experimental results show that resonant frequencies of the bonded structure vary sensitively with the interface stiffness constants and adhesive thickness, and these interface characteristics are inversed by the simulation annealing （SA） method. Furthermore, the distribution image of interface stiffnesses is compared with the state of fracture interface, and quantitative prediction of shear strength is achieved based on the distribution of interface stiffnesses and adhesive thicknesses by using a back- propagation neutral network. The average relative error of the shear strength from prediction to real value is 10.7%.

关键词： Ultrasonics Fractures Waves Adhesives Ultrasound imaging Numerical simulations

UPLC-Q-TOF/MS-Based Serum Metabolomics Reveals Potential Anti-tumor Mechanism of Banxia Xiexin Decoction in Colorectal Cancer Mice

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Chinese Journal of Integrative Medicine 2024年第7期30卷 623-632页

作者： YUE Yin-zi li ming-xuan WANG Xiao-hui QIN Yuan-yuan WANG Ya-hui TAN Jin-hua SU lian-lin YAN Shuai Department of General Surgery Suzhou TCM Hospital Affiliated to Nanjing University of Chinese MedicineSuzhou215009China School of Pharmacy Nanjing University of Chinese MedicineNanjing210023China Department of General Surgery Bayinguoleng Mongolian Autonomous Prefecture People’s HospitalXinjiang Uygur Autonomous RegionKorla841000China Department of Pharmacy Suzhou TCM Hospital Affiliated to Nanjing University of Chinese MedicineSuzhou215009China Department of Anorectal Surgery Suzhou TCM Hospital Affiliated to Nanjing University of Chinese MedicineSuzhou215009China

Objective To clarify the potential mechanism of Banxia Xiexin Decoction(BXD)on colorectal cancer(CRC)from the perspective of *** Forty male C57BL/6 mice were randomly divided into normal control(NC),azoxymethane/dextran sulfate sodium(AOM/DSS)model,low-dose BXD(L-BXD),high-dose BXD(H-BXD)and mesalamine(MS)groups according to a random number table,8 mice in each *** cancer model was induced by AOM/*** was administered daily at doses of 3.915(L-BXD)and 15.66 g/kg(H-BXD)by gavage for consecutive 21 days,and 100 mg/kg MS was used as positive *** the entire modeling cycle,colon length of mice was measured and quantity of colorectal tumors were *** spleen and thymus index were determined by calculating the spleen/thymus weight to body *** cytokine and changes of serum metabolites were analyzed by enzyme-linked immunosorbent assay kits and ultra performance liquid chromatography-quadrupole/time-of-flight mass spectrometry(UPLC-Q/TOF-MS),*** Notably,BXD supplementation protected against weight loss,mitigated tumor formation,and diminished histologic damage in mice treated with AOM/DSS(Plites were screened in the AOM/DSS group,including 48 potential biomarkers,involving 18 main metabolic *** 18 potential biomarkers related to CRC were identified,and the anti-CRC mechanism of BXD was closely related to D-glutamine and D-glutamate metabolism,phenylalanine,tyrosine and tryptophan biosynthesis,arginine biosynthesis,nitrogen metabolism and so *** BXD exerts partial protective effects on AOM/DSS-induced CRC by reducing inflammation,protecting organism immunity ability,and regulating amino acid metabolism.

关键词： colorectal cancer metabolomics ultra performance liquid chromatography-quadrupole/time-of-flight mass spectrometry azoxymethane dextran sulfate sodium Banxia Xiexin Decoction Chinese medicine

Oxidative Methylation of Toluene with Methane overK-exchanged Y Type Zeolite Catalyst Promoted with Alkali Metal Bromide and Alkali Metal Oxide

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Chemical Research in Chinese Universities 1996年第1期12卷 120-124页

作者： ZHOU ling-ping TAO Ke-yi li Wei SU ming and li He-xuan(Department of Chemistry, Nakai University, Tianjin, 300071 )Hideshi Hattori(Hokkaido University, Sapporo, Japan) NANKAI UNIV DEPT CHEMTIANJIN 300071PEOPLES R CHINA HOKKAIDO UNIV SAPPOROHOKKAIDO 060JAPAN

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塑性混凝土墙在病险土石坝加固中的应用

中国农村水利水电 2009年第6期 79-81,84页

作者：李煊明福建省水利水电勘测设计研究院福建福州350001

经过有限元计算和对比分析,基于混凝土弹性模量越高,拉应力越大,防渗墙与坝体的变形越不协调,相应提出了病险土石坝防渗墙宜采用低弹模塑性混凝土的看法;经过长期的防渗墙材料试验和研究认为,随着水泥用量的增加,塑性混凝土强度、弹性... 详细信息

经过有限元计算和对比分析,基于混凝土弹性模量越高,拉应力越大,防渗墙与坝体的变形越不协调,相应提出了病险土石坝防渗墙宜采用低弹模塑性混凝土的看法;经过长期的防渗墙材料试验和研究认为,随着水泥用量的增加,塑性混凝土强度、弹性模量增加,弹强比也略增大,极限应变则降低;根据福建省病险土石坝特点配设的塑性混凝土材料配合比和试验研究的物理力学性能指标,可供类似工程设计参考。

关键词：土石坝加固塑性混凝土应力应变材料试验应用研究

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基于元数据规范的入侵检测研究与实现

微计算机信息 2008年第36期24卷 96-98页

作者：李名选北京市科学技术委员会北京100035

入侵检测是档案信息安全保障体系建设的重要组成部分,而在分布式入侵检测系统中,数据信息量大、格式非常多样化,直接对原始数据进行处理和交换的效率非常低,针对此问题,采用一种基于元数据规范的方法,对数据对象进行规范化描述,统一数... 详细信息

入侵检测是档案信息安全保障体系建设的重要组成部分,而在分布式入侵检测系统中,数据信息量大、格式非常多样化,直接对原始数据进行处理和交换的效率非常低,针对此问题,采用一种基于元数据规范的方法,对数据对象进行规范化描述,统一数据格式,提高数据挖掘效率,为多系统、多模块的协作提供了一种有效的数据交换方式。

关键词：入侵检测元数据规范数据挖掘可扩展标识语言

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超声检测用压电换能器瞬态特性可控可调

应用声学 2008年第5期27卷 338-344页

作者：李明轩中国科学院声学研究所北京100190

超声检测用压电换能器瞬态特性主要包括瞬态空间响应和瞬态时间响应。本文通过调整控制换能器和激励源,实现瞬态空间响应和瞬态时间响应的某些特性的可控可调。其中包括在空间响应方面消除边缘波以获得平行声束和消除平面波以获得聚焦... 详细信息

超声检测用压电换能器瞬态特性主要包括瞬态空间响应和瞬态时间响应。本文通过调整控制换能器和激励源,实现瞬态空间响应和瞬态时间响应的某些特性的可控可调。其中包括在空间响应方面消除边缘波以获得平行声束和消除平面波以获得聚焦绳声束;在时间响应方面,调整换能器的背衬阻抗以获得可调首次波幅比和调整换能器结构和激励电信号以获得任意检测信号等。

关键词：瞬态空间响应瞬态时间响应任意检测信号

MOF衍生碳基材料的电催化应用及其先进表征技术

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新型炭材料（中英文） 2024年第1期39卷 78-99页

作者：陈曦李明轩闫金伦张龙力中国石油大学(华东)化学化工学院山东青岛266580 中国石油大学(华东)重质油国家重点实验室山东青岛266580

鉴于对清洁和可持续能源的需求,来自金属有机框架(MOFs)的纳米炭衍生物正崭露头角,成为电催化能量转化的独特催化剂。这些MOF衍生的纳米炭材料不仅保持了MOFs组成可定制和结构多样性等优势,而且在热解过程中可有效防止金属纳米颗粒和金... 详细信息

鉴于对清洁和可持续能源的需求,来自金属有机框架(MOFs)的纳米炭衍生物正崭露头角,成为电催化能量转化的独特催化剂。这些MOF衍生的纳米炭材料不仅保持了MOFs组成可定制和结构多样性等优势,而且在热解过程中可有效防止金属纳米颗粒和金属氧化物的聚集。因此,它们提高了电催化效率,改善了电导率,并在燃料电池和金属-空气电池等绿色能源技术中发挥了关键作用。该综述以MOF衍生碳基材料的炭化机制为起点,随后深入探讨了固有炭缺陷、金属和非金属原子掺杂,并研究了这些材料的合成策略。此外,全面介绍了先进的表征技术,包括原位映射和原位光谱学。最后,对MOF衍生碳基材料作为电催化剂的研究前景提供了见解。该综述的主要目标是为当前MOF衍生碳基电催化剂的状况提供更清晰的视角,鼓励更高效电催化材料的发展。

关键词：金属-有机框架材料纳米炭材料电催化先进表征方法

Cell polarization in ischemic stroke: molecular mechanisms and advances

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Neural Regeneration Research 2025年第3期20卷 632-645页

作者： Yuanwei li Xiaoxiao Xu xuan Wu Jiarui li Shiling Chen Danyang Chen Gaigai li Zhouping Tang Department of Neurology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

Ischemic stroke is a cerebrovascular disease associated with high mortality and disability rates. Since the inflammation and immune response play a central role in driving ischemic damage, it becomes essential to modulate excessive inflammatory reactions to promote cell survival and facilitate tissue repair around the injury site. Various cell types are involved in the inflammatory response, including microglia, astrocytes, and neutrophils, each exhibiting distinct phenotypic profiles upon stimulation. They display either proinflammatory or anti-inflammatory states, a phenomenon known as ‘cell polarization.’ There are two cell polarization therapy strategies. The first involves inducing cells into a neuroprotective phenotype in vitro, then reintroducing them autologously. The second approach utilizes small molecular substances to directly affect cells in vivo. In this review, we elucidate the polarization dynamics of the three reactive cell populations(microglia, astrocytes, and neutrophils) in the context of ischemic stroke, and provide a comprehensive summary of the molecular mechanisms involved in their phenotypic switching. By unraveling the complexity of cell polarization, we hope to offer insights for future research on neuroinflammation and novel therapeutic strategies for ischemic stroke.

关键词： astrocyte polarization immune regulation inflammation ischemic injury microglia polarization neutrophil polarization signaling pathways stroke

Wafer‑Scale Vertical 1D GaN Nanorods/2D MoS_(2)/PEDOT:PSS for Piezophototronic Effect‑Enhanced Self‑Powered Flexible Photodetectors

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Nano-Micro Letters 2025年第3期17卷 102-116页

作者： Xin Tang Hongsheng Jiang Zhengliang lin xuan Wang Wenliang Wang Guoqiang li State Key Laboratory of Luminescent Materials and Devices South China University of TechnologyGuangzhou 510640People’s Republic of China Department of Electronic Materials School of Materials Science and EngineeringSouth China University of TechnologyGuangzhou 510640People’s Republic of China

van der Waals(vdW)heterostructures constructed by lowdimensional(0D,1D,and 2D)materials are emerging as one of the most appealing systems in next-generation flexible ***,hand-stacked vdW-type photodetectors are not compatible with large-areaarray fabrication and show unimpressive performance in self-powered ***,vertical 1D GaN nanorods arrays(NRAs)/2D MoS_(2)/PEDOT:PSS in wafer scale have been proposed for self-powered flexible photodetectors arrays *** as-integrated device without external bias under weak UV illumination exhibits a competitive responsivity of 1.47 A W^(−1)and a high detectivity of 1.2×10^(11)Jones,as well as a fast response speed of 54/71μs,thanks to the strong light absorption of GaN NRAs and the efficient photogenerated carrier separation in type-II ***,the strain-tunable photodetection performances of device have been ***,the device at−0.78%strain and zero bias reveals a significantly enhanced photoresponse with a responsivity of 2.47 A W^(−1),a detectivity of 2.6×10^(11)Jones,and response times of 40/45μs,which are superior to the state-of-the-art self-powered flexible *** work presents a valuable avenue to prepare tunable vdWs heterostructures for self-powered flexible photodetection,which performs well in flexible sensors.

关键词： Vertical nanorod arrays van der Waals heterostructure Piezophototronic effect Self-powered photodetection Flexible sensors