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Effect of short neuropeptide F signaling on larval feeding in Mythimna separata

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Insect Science 2024年第2期31卷 417-434页

作者： Mei-Mei li Qi Yang li-Hui Chen Yan-Ying li Jun-Xiang Wu Xiang-li Xu State Key Laboratory of Crop Stress Biology in Arid Areas College of Plant ProtectionNorthwest A&F UniversityYanglingShaanxi ProvinceChinaand School of Agricultural Sciences Jiangxi Agricultural UniversityNanchangChina

Mythimna separata is a notorious phytophagous pest which poses serious threats to cereal crops owing to the gluttony of the larvae.Because short neuropeptide F(sNPF)and its receptor sNPFR are involved in a diversity of physiological functions,especially in functions related to feeding in insects,it is a molecular target for pest control.Herein,an sNPF and 2 sNPFRs were identified and cloned from M.separata.Bioinformatics analysis revealed that the sNPF and its receptors had a highly conserved RLRFamide C-terminus and 7 transmembrane domains,respectively.The sNPF and its receptor genes were distributed across larval periods and tissues,but 2 receptors had distinct expression patterns.The starvation-induced assay elucidated that sNPF and sNPFR expression levels were downregulated under food deprivation and recovered with subsequent re-feeding.RNA interference knockdown of sNPF,sNPFR1,and sNPFR2 by injection of double-stranded RNA into larvae not only suppressed food consumption and increased body size and weight,but also led to decrease of glycogen and total lipid contents,and increase of trehalose compared with double-stranded green fluorescent protein injection.Furthermore,molecular docking was performed on the interaction mode between sNPFR protein and its ligand sNPF based on the 3-dimensional models constructed by AlphaFold;the results indicated that both receptors were presumably activated by the mature peptide sNPF-2.These results revealed that sNPF signaling played a considerably vital role in the feeding regulation of M.separata and represents a potential control target for this pest.

关键词： feeding regulation Mythimna separata pest control target RNA interference short neuropeptide F sNPF receptors

Heralded entanglement between error-protected logical qubits for fault-tolerant distributed quantum computing

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Science China(Physics,Mechanics & Astronomy) 2024年第2期67卷 25-33页

作者： Jialun li Zhihao Xie Yachen li Yansen liang Zhenhua li Tao li MIIT Key Laboratory of Semiconductor Microstructure and Quantum Sensing School of PhysicsNanjing University of Science and TechnologyNanjing 210094China National Laboratory of Solid State Microstructures Nanjing UniversityNanjing 210093China

Quantum error correction is essential for achieving reliable quantum information processing tasks,as it can mitigate the detrimental effects of noise by encoding single-qubit information into a larger quantum system.However,the generation of distributed entanglement between logical qubits located within two spatially separated nodes presents a significant resource-intensive challenge that has yet to be overcome.Here we present a heralded protocol for generating distributed entanglement between two nonlocal error-protected logical qubits.A high-dimensional single photon can evolve physical qubits into a logical qubit that entangles with the photon and then converts logical qubit-photon entanglement into entanglement between two logical qubits,when the photon state is properly tuned and an effective photon-spin interface between single photons and individual spins is exploited.Furthermore,the success of the entanglement generation is heralded by the detection of the photon,and the corresponding efficiency can,in principle,approach unity.These distinguished features make our protocol highly appealing for future large-scale quantum technologies.

关键词： quantum networks distributed entanglement error-protected logical qubits high-dimensional photons

An internal ballistic model of electromagnetic railgun based on PFN coupled with multi-physical field and experimental validation

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Defence Technology（防务技术） 2024年第2期32卷 254-261页

作者： Benfeng Gu Haiyuan li Baoming li National Key Laboratory of Transient Physics Nanjing University of Science and TechnologyNanjing 210094China

To accelerate the practicality of electromagnetic railguns,it is necessary to use a combination of threedimensional numerical simulation and experiments to study the mechanism of bore damage.In this paper,a three-dimensional numerical model of the augmented railgun with four parallel unconventional rails is introduced to simulate the internal ballistic process and realize the multi-physics field coupling calculation of the rail gun,and a test experiment of a medium-caliber electromagnetic launcher powered by pulse formation network(PFN)is carried out.Various test methods such as spectrometer,fiber grating and high-speed camera are used to test several parameters such as muzzle initial velocity,transient magnetic field strength and stress-strain of rail.Combining the simulation results and experimental data,the damage condition of the contact surface is analyzed.

关键词： Internal ballistic modeling Electromagnetic rail gun Multi-physics field coupling Experimental validation PFN

Al/Hf ratio-dependent mechanisms of microstructure and mechanical property of nearly fully dense Al—Hf reactive material

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Defence Technology（防务技术） 2024年第1期31卷 230-241页

作者： Junbao li Weibing li Xiaoming Wang ZNDY of Ministerial Key Laboratory Nanjing University of Science and TechnologyNanjing 210094China

This study proposed three types of Al—Hf reactive materials with particle size ratios(a),which were almost completely dense(porosity of<5.40%)owing to their preparation using hot-pressing technology.Microstructure ch... 详细信息

This study proposed three types of Al—Hf reactive materials with particle size ratios(a),which were almost completely dense(porosity oflinearly with increasing strain rate.ε.It is found that the plastic deformation of the material increased with increasing strain rate.As a increased from 0.1 to 1,the flow stress gradually increased.Impact failure of the material was dominated by ductile fracture with a large Al phase plastic deformation band for lower a,while brittle fracture with crushed Hf particles occurred at higher a.Finally,a constitutive model based on BP neural network was proposed to describe the stress-strain relationships of the materials,with an average relative error of 2.22%.

关键词： Reactive material Particle size Split Hopkinson pressure bar test Stressestrain relationship Impact failure BP neural network

Advances in microfluidic-based DNA methylation analysis

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Nanotechnology and Precision Engineering 2024年第1期7卷 116-134页

作者： Jiwen li Tiechuan li Xuexin Duan State Key Laboratory of Precision Measuring Technology and Instruments Tianjin UniversityTianjin 300072China

DNA methylation has been extensively investigated in recent years,not least because of its known relationship with various diseases.Progress in analytical methods can greatly increase the relevance of DNA methylation studies to both clinical medicine and scientiﬁc research.Microﬂu-idic chips are excellent carriers for molecular analysis,and their use can provide improvements from multiple aspects.On-chip molecular analysis has received extensive attention owing to its advantages of portability,high throughput,low cost,and high efﬁciency.In recent years,the use of novel microﬂuidic chips for DNA methylation analysis has been widely reported and has shown obvious superiority to conventional methods.In this review,weﬁrst focus on DNA methylation and its applications.Then,we discuss advanced microﬂuidic-based methods for DNA methylation analysis and describe the great progress that has been made in recent years.Finally,we summarize the advantages that microﬂuidic technology brings to DNA methylation analysis and describe several challenges and perspectives for on-chip DNA methylation analysis.This review should help researchers improve their understanding and make progress in developing microﬂuidic-based methods for DNA methylation analysis.

关键词： Microﬂuidic chip DNA methylation analysis Molecular analysis High throughput Low cost

Topology Optimization Method for Microscale Structures Described with Integral Nonlocal Theory

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Acta Mechanica Solida Sinica 2024年第1期37卷 63-71页

作者： Jiayu li Quhao li Shutian liu State Key Laboratory of Structural Analysis Optimization and CAE Software for Industrial EquipmentDalian University of TechnologyDalian 116024China

The integration of additive manufacturing and topology optimization makes it possible to fabricate complex configurations,especially for microscale structures,which can guarantee the realization of high-performance structural designs.However,topology results often contain microstructures(several multicellular scales)similar to the characteristic length of local macrostructures,leading to errors in structural performance analysis based on classical theories.Therefore,it is necessary to consider the size effect in topology optimization.In this paper,we establish a novel topology optimization model utilizing the integral nonlocal theory to account for the size effect.The approach consists of an integral constitutive model that incorporates a kernel function,enabling the description of stress at a specific point in relation to strain in a distant field.Topology optimization structures based on nonlocal theory are presented for some benchmark examples,and the results are compared with those based on classical medium theory.The material layout exhibits significant differences between the two approaches,highlighting the necessity of topology optimization based on nonlocal theory and the effectiveness of the proposed method.

关键词： Topology optimization Microstructures Integral nonlocal theory Size effect

Gravitational waves and primordial black hole productions from gluodynamics by holography

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Science China(Physics,Mechanics & Astronomy) 2024年第4期67卷 31-42页

作者： Song He li li Zhibin li Shao-Jiang Wang Center for Theoretical Physics and College of Physics Jilin UniversityChangchun 130012China Max Planck Institute for Gravitational Physics(Albert Einstein Institute) Golm 14476Germany CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China School of Fundamental Physics and Mathematical Sciences Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesHangzhou 310024China Peng Huanwu Collaborative Center for Research and Education Beihang UniversityBeijing 100191China School of Physics and Microelectronics Zhengzhou UniversityZhengzhou 450001China

Understanding the nature of quantum chromodynamics(QCD)matter is important but challenging due to the presence of nonperturbative dynamics under extreme conditions.We construct a holographic model describing the gluon sector of QCD at finite temperatures in the non-perturbative regime.The equation of state as a function of temperature is in good accordance with the lattice QCD data.Moreover,the Polyakov loop and the gluon condensation,which are proper order parameters to capture the deconfinement phase transition,also agree quantitatively well with the lattice QCD data.We obtain a strong first-order confinement/deconfinement phase transition at Tc=276.5 Me V that is consistent with the lattice QCD prediction.Based on our model for a pure gluon hidden sector,we compute the stochastic gravitational waves and primordial black hole(PBH)productions from this confinement/deconfinement phase transition in the early Universe.The resulting stochastic gravitational-wave backgrounds are found to be within detectability in the International Pulsar Timing Array and Square Kilometre Array in the near future when the associated productions of PBHs saturate the current observational bounds on the PBH abundances from the liGO-Virgo-Collaboration O3 data.

关键词： AdS/QCD confinement/deconfinement phase transition gravitational wave primordial black hole

Diffusionmodels for time-series applications: a survey

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Frontiers of Information Technology & Electronic Engineering 2024年第1期25卷 19-41页

作者： Lequan liN Zhengkun li Ruikun li Xuliang li Junbin GAO Discipline of Business Analytics The University of Sydney Business SchoolCamperdownNSW 2006Australia Postdoctoral Programme of Zhongtai Securities Co. Ltd.Jinan 250000China

Diffusion models, a family of generative models based on deep learning, have become increasinglyprominent in cutting-edge machine learning research. With distinguished performance in generating samples thatresemble the observed data, diffusion models are widely used in image, video, and text synthesis nowadays. Inrecent years, the concept of diffusion has been extended to time-series applications, and many powerful models havebeen developed. Considering the deficiency of a methodical summary and discourse on these models, we providethis survey as an elementary resource for new researchers in this area and to provide inspiration to motivate futureresearch. For better understanding, we include an introduction about the basics of diffusion models. Except forthis, we primarily focus on diffusion-based methods for time-series forecasting, imputation, and generation, andpresent them, separately, in three individual sections. We also compare different methods for the same applicationand highlight their connections if applicable. Finally, we conclude with the common limitation of diffusion-basedmethods and highlight potential future research directions.

关键词： Diffusion models Time-series forecasting Time-series imputation Denoising diffusion probabilistic models Score-based generative models Stochastic differential equations

Guidance strategy of motion camouflage for spacecraft pursuit-evasion game

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Chinese Journal of Aeronautics 2024年第3期37卷 312-319页

作者： Jianqing li Chaoyong li Yonghe ZHANG Space Information Research Institute Hangzhou Dianzi UniversityHangzhou 310018China College of Electrical Engineering Zhejiang UniversityHangzhou 310027China Key Lab of Microsatellites Chinese Academy of SciencesShanghai 201210China

This work is inspired by a stealth pursuit behavior called motion camouflage whereby a pursuer approaches an evader while the pursuer camouflages itself against a predetermined background.We formulate the spacecraft pursuit-evasion problem as a stealth pursuit strategy of motion camouflage,in which the pursuer tries to minimize a motion camouflage index defined in this paper.The Euler-Hill reference frame whose origin is set on the circular reference orbit is used to describe the dynamics.Based on the rule of motion camouflage,a guidance strategy in open-loop form to achieve motion camouflage index is derived in which the pursuer lies on the camouflage constraint line connecting the central spacecraft and evader.In order to dispose of the dependence on the evader acceleration in the open-loop guidance strategy,we further consider the motion camouflage pursuit problem within an infinite-horizon nonlinear quadratic differential game.The saddle point solution to the game is derived by using the state-dependent Riccati equation method,and the resulting closed-loop guidance strategy is effective in achieving motion camouflage.Simulations are performed to demonstrate the capabilities of the proposed guidance strategies for the pursuit–evasion game scenario.

关键词： Pursuit-evasion problem Motion camouflage Differential game Guidance strategy Orbit control