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Journal of Traditional Chinese Medicine 2015年第5期35卷 577-582页

作者： Wang Wei li jiquan Meng Xiangyu Chen Yiguo College of Acupuncture and Massage Liaoning University of Traditional Chinese Medicine

OBJECTIVE:To investigate the effects of electronic stimulation at acupoints Neiguan(PC 6) and lieque(LU 7) on the gene expression of the adenosine triphosphate(ATP)-Sensitive potassium channel(KATP:Kir6.1,Kir6.2,SUR2 A,and SUR2B) and protein kinases(PKA,PKG,and PKCβ2) in myocardial cells of rats with myocardial ischemia(Ml) induced by isoproterenol(ISO).METHODS:Rats were randomly divided into a control,model,Neiguan(PC 6),lieque(LU 7),and non-acupoint *** Ml model was established by injecting rats with ***-acupuncture treatment was given to the acupuncture groups,once a day for 7 *** expression was analyzed with real-time ***:The gene expression of KATP and protein kinases in the model group was higher than those in the control group(P lieque(LU 7) groups compared with the model group[P lieque(LU 7) group(P 0.05).CONCLUSION:Our findings suggest that electronic needling of Neiguan(PC 6) can both reduce the gene expression of KATP and protein kinases in rats with ISO-induced Ml.

关键词：蛋白激酶基因 PCR分析急性心肌缺血钾离子通道三磷酸腺苷基因表达心肌细胞大鼠

电针激痛点对肌筋膜疼痛综合征大鼠BDNF、NGF表达的影响

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辽宁中医药大学学报 2024年第5期26卷 141-145页

作者：王列马帅马俊杰于嘉祥王树东李记泉李格格胡哲卞镝王鹰马铁明辽宁中医药大学辽宁沈阳110847 辽宁省针灸养生康复重点实验室辽宁沈阳110847 沈阳市第七人民医院辽宁沈阳110003

目的探讨电针疗法对肌筋膜疼痛综合征(MPS)大鼠促炎性因子、氧化应激和脊髓神经生长因子(NGF)、脑源性神经营养因子(BDNF)的影响。方法24只SPF级SD大鼠随机分为空白组(n=8)、模型组(n=8)、电针组(n=8)。模型组和电针组通过打击结合离心... 详细信息

目的探讨电针疗法对肌筋膜疼痛综合征(MPS)大鼠促炎性因子、氧化应激和脊髓神经生长因子(NGF)、脑源性神经营养因子(BDNF)的影响。方法24只SPF级SD大鼠随机分为空白组(n=8)、模型组(n=8)、电针组(n=8)。模型组和电针组通过打击结合离心运动方式建立MPS模型,造模后电针组给予电针干预。分别于造模前、造模后及治疗后对3组进行热缩足潜伏期检测;HE染色法观察大鼠肌细胞形态学变化;用EliSA技术检测各组大鼠血清促炎细胞因子白细胞介素-1(IL-1)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)和氧化应激指标超氧化物歧化酶(SOD)、丙二醛(MDA)、谷胱甘肽过氧化物酶(GSH-Px)、过氧化氢酶(CAT)的水平;Western blot检测大鼠L4~6脊髓NGF及BDNF的蛋白表达水平;实时荧光定量PCR(RT-PCR)检测NGF和BDNF的mRNA表达水平。结果与空白组相比,模型组大鼠热缩足潜伏期时间明显缩短,电针干预后明显延长(P<0.01)。与空白组相比,模型组大鼠出现膨大、圆染的肌细胞,核内移明显,电针干预后肌细胞大小形状规则,较为接近正常组肌组织形态;与空白组相比,模型组大鼠血清促炎性因子IL-1β、IL-6、TNF-α水平显著升高,经电针干预后显著降低(P<0.01);与空白组相比,模型组大鼠血清SOD、GSH-px、CAT水平显著降低,MDA水平显著升高(P<0.01);与模型组相比,电针组大鼠血清SOD、GSH-px、CAT水平显著升高,MDA水平显著降低(P<0.01);与空白组相比,模型组大鼠脊髓组织NGF、BDNF的蛋白和mRNA表达水平显著升高;与模型组相比,电针组大鼠脊髓组织NGF、BDNF的蛋白和mRNA表达水平显著降低(P<0.01)。结论电针可以显著降低MPS大鼠的疼痛阈值,具体机制涉及了对促炎性因子和氧化应激的抑制,同时又与降低NGF、BDNF的蛋白和mRNA表达水平有关。

关键词：电针肌筋膜疼痛综合征神经生长因子脑源性神经营养因子

环氧树脂粘度和充磁次数对两步室温压各向异性粘结Nd-Fe-B磁体性能的影响

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中国稀土学报 2024年第4期42卷 705-711页

作者：马斌张鹏杰王继全李青华李炳山孙威矿冶科技集团有限公司北矿磁材(阜阳)有限公司

采用两步室温压工艺即室温预成型+高温取向成型制备各向异性粘结Nd-Fe-B磁体，研究了环氧树脂粘度和交变磁场充磁次数对磁体性能的影响。环氧树脂在140℃时粘度较小（约150 Pa·s）且具有一个较长的低粘度平台（约200 s），预成型坯体在... 详细信息

采用两步室温压工艺即室温预成型+高温取向成型制备各向异性粘结Nd-Fe-B磁体，研究了环氧树脂粘度和交变磁场充磁次数对磁体性能的影响。环氧树脂在140℃时粘度较小（约150 Pa·s）且具有一个较长的低粘度平台（约200 s），预成型坯体在140℃保温1 min时预热效果最好，制备的粘结磁体具有最高的最大磁能积(（BH）max)、取向度（DOA）和密度(127 kJ·m-3,0.55,5.91 g·cm-3)。140℃保温1 min时，粘结磁体（BH）max,DOA在交变磁场充磁2次时达到最大值(133 k J·m-3、0.59);140℃保温6 min时，粘结磁体（BH）max,DOA在交变磁场充磁4次时达到最大值(108 k J·m-3、0.52)；密度则随着交变磁场充磁次数的增加逐渐降低。随着保温时间的延长，环氧树脂粘度增大，流动性降低，导致粘结磁体（BH）max,DOA和密度降低，可以通过增加交变磁场充磁次数使粉末颗粒向磁场方向转动来提高磁体DOA，进而提高（BH）max。

关键词：粘结Nd-Fe-B磁体环氧树脂粘度交变磁场

Machine learning of turbulent transport in fusion plasmas with neural network

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Plasma Science and Technology 2021年第11期23卷 9-17页

作者：李慧付艳林李继全王正汹 Key Laboratory of Materials Modification by Laser Ionand Electron Beams(Ministry of Education)School of Physics.Dalian University of TechnologyDalian 116024People's Republic of China Southwestern Institute of Physics Chengdu 610041People's Republic of China School of Physics Dalian University of TechnologyDalian 116024People's Republic of China

Turbulent transport resulting from drift waves,typically,the ion temperature gradient(ITG)mode and trapped electron mode(TEM),is of great significance in magnetic confinement *** is also well known that turbulence simulation is a challenging issue in both the complex physical model and huge CPU cost as well as long computation *** this work,a credible turbulence transport prediction model,extended fluid code(ExFC-NN),based on a neural network(NN)approach is established using simulation data by performing an ExFC,in which multi-scale multi-mode fluctuations,such as ITG and TEM turbulence are *** show that the characteristics of turbulent transport can be successfully predicted including the type of dominant turbulence and the radial averaged fluxes under any set of local gradient ***,a global NN model can well reproduce the radial profiles of turbulence perturbation intensities and fluxes much faster than existing codes.A large number of comparative predictions show that the newly constructed NN model can realize rapid experimental analysis and provide reference data for experimental parameter design in the future.

关键词： neural network plasma turbulence transport properties plasma simulation

Role of the zonal flow in multi-scale multi-mode turbulence with small-scale shear flow in tokamak plasmas

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Chinese Physics B 2022年第6期31卷 549-556页

作者：李慧李继全王正汹魏来胡朝清 Key Laboratory of Materials Modification by Beams of the Ministry of Education School of PhysicsDalian University of TechnologyDalian 116024China Southwestern Institute of Physics Chengdu 610041China

The structural characteristics of zonal flows and their roles in the nonlinear interaction of multi-scale multi-mode turbulence are investigated numerically via a self-consistent Landau-fluid *** multi-mode turbulence here is composed of a shorter wavelength electromagnetic(EM)ion temperature gradient(ITG)mode and a Kelvin-Helmholtz(KH)instability with long wavelengths excited by externally imposed small-scale shear *** strong shear flow,a prominent periodic intermittency of fluctuation intensity except for dominant ITG component is revealed in turbulence evolution,which onset time depends on the ion temperature gradient and the shear flow amplitudes corresponding to different KH *** is identified that the intermittency phenomenon results from the zonal flow dynamics,which is mainly generated by the KH mode and back-reacts on *** is demonstrated that the odd symmetric components of zonal flow(same symmetry as the external flow)make the radial parity of the KH mode alteration through adjusting the drift velocities at two sides of the resonant surface so that the KH mode becomes bursty ***,the ITG intermittency follows due to nonlinear mode *** dependences of the features of the intermittency are ***,associated turbulent heat transport is evaluated.

关键词： drift waves turbulence nonlinear phenomena plasma simulation

Recent advances in high-β_(N) experiments and magnetohydrodynamic instabilities with hybrid scenarios in the HL-2A Tokamak

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Fundamental Research 2022年第5期2卷 667-673页

作者： Wei Chen liming Yu Min Xu Xiaoquan Ji Zhongbing Shi Xiaoxue He Zhengji li Yonggao li Tianbo Wang Min Jiang Shaobo Gong Jie Wen Peiwan Shi Zengchen Yang Kairui Fang Jia li Lai Wei Wulv Zhong Aiping Sun Jianyong Cao Xingyu Bai jiquan li Xuantong Ding Jiaqi Dong Qingwei Yang Yi liu Longwen Yan Zhengxiong Wang Xuanru Duan Joint Laboratory for Fusion Product and Energetic Particle Southwestern Institute of PhysicsP.O.Box 432Chengdu 610041China Key Laboratory of Materials Modification by Beams of the Ministry of Education School of PhysicsDalian University of TechnologyDalian 116024China

Over the past several years,high-β_(N) experiments have been carried out on *** high-β_(N) is realized using double transport barriers(DTBs)with hybrid scenarios.A stationary high-β_(N) (>2)scenario was obtained by pure neutral-beam injection(NBI)*** high performance was also achieved,corresponding to β_(N)≥3,ne/ne_(G)∼0.6,H_(98)∼1.5,f_(bs)∼30%,q_(95)∼4.0,and𝐺∼*** high-β_(N) scenario was successfully modeled using integrated simulation codes,that is,the one modeling framework for integrated tasks(OMFIT).In high-𝛽𝑁plasmas,magnetohydrodynamic(MHD)instabilities are abundant,including low-frequency global MHD oscilla-tion with n=1,high-frequency coherent mode(HCM)at the edge,and neoclassical tearing mode(NTM)and Alfvénic modes in the *** some high-β_(N) discharges,it is observed that the NTMs with m/n=3/2 limit the growth of the plasma energy and decrease β_(N).The low-n global MHD oscillation is consistent with the coupling of destabilized internal(m/n=1/1)and external(m/n=3/1 or 4/1)modes,and plays a crucial role in triggering the onset of *** high-β_(N) on HL-2A suggests that core-edge interplay is key to the plasma confinement enhancement *** to enhance β_(N) will contribute to future plasma operation,such as international thermonuclear experimental reactor.

关键词： High-β_(N) Transport barrier Hybrid scenario Bootstrapcurrent Magnetohydrodynamic

城市建筑生态位原理探析及其生态位策略研究——日本东京中城规划设计案例分析

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城市发展研究 2012年第8期19卷 28-35页

作者：李积权福建工程学院

如同自然生物体的产生、生长、成熟和衰亡一样,一栋城市建筑通常要经历从材料的开采、加工运输、规划设计、建造、使用维修、更新改造,直到最后拆除、废弃物处置的整个"生命周期"过程。城市中的建筑活动涉及材料、技术、能源、社会、经... 详细信息

如同自然生物体的产生、生长、成熟和衰亡一样,一栋城市建筑通常要经历从材料的开采、加工运输、规划设计、建造、使用维修、更新改造,直到最后拆除、废弃物处置的整个"生命周期"过程。城市中的建筑活动涉及材料、技术、能源、社会、经济、文化等诸多因素,是一个复合生态系统。以城市建筑为生态元,视影响城市建筑的各种自然和社会要素为生态因子,引入生态位概念,探析城市建筑生态位原理,构建城市建筑生态位;举例分析,从自然与社会两方面探讨可持续发展的城市建筑生态位策略,为建设低碳生态城市提供一种新的思路和实践方法,从而打开研究城市建筑规划设计的新视角。

关键词：生态位城市建筑生态位生态位策略东京中城

Geodesic Acoustic Mode in Toroidally Axisymmetric Plasmas with Non-Circular Cross Sections

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Southwestern Institute of Physics Annual Report 2004年第1期 115-118页

作者： SHI Bingren li jiquan DONG Jiaqi

Semi-analytic Modeling of Tokamak Particle Transport

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中国核科技报告 1999年第S3期 3-5页

作者： SHI Bingren LONG Yongxin li jiquan

Plasma particle transport is one of the most fundamental and important issues relevant to the global energy confinement time due not only to its effect on total energy storage but also to that the profile of the particle density is critical to the confinement mode. The study of particle transport generally includes the working particles like H, D and impurities. This paper is an extension of that described in Ref. [1]. Assuming the operator in transport equation is linear, we express the solution in a form based on the Green function or, equivalently, in generalized Fourier expansion. For space-dependent diffusion coefficient and convection, it is necessary to do some numerical calculation

关键词： Particle transport Complementarity Generalized Fourier expansion

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机翼蒙皮铺层顺序和材料布局协同优化

中国机械工程 2023年第12期34卷 1415-1424,1435页

作者：彭翔江浩浩郭玉良李吉泉易兵姜少飞浙江工业大学机械工程学院杭州310023 浙江工业大学高端激光制造装备省部共建协同创新中心杭州310023 中南大学交通运输工程学院长沙410083

为了实现机翼蒙皮的轻量化和减振设计,将混杂复合材料引入到机翼蒙皮中,提出了机翼蒙皮铺层顺序和材料布局协同优化设计方法。将机翼蒙皮的铺层顺序和材料布局作为优化设计变量,建立了以成本为约束,蒙皮质量和位移最小化、频率最大化为... 详细信息

为了实现机翼蒙皮的轻量化和减振设计,将混杂复合材料引入到机翼蒙皮中,提出了机翼蒙皮铺层顺序和材料布局协同优化设计方法。将机翼蒙皮的铺层顺序和材料布局作为优化设计变量,建立了以成本为约束,蒙皮质量和位移最小化、频率最大化为目标的协同优化模型,利用搭建的通用化机翼蒙皮优化设计框架,使用非支配排序遗传算法-Ⅱ(NSGA-Ⅱ)实现了蒙皮内部结构的优化设计。与铝合金机翼蒙皮、初始结构方案蒙皮的性能对比表明,协同优化后的机翼蒙皮结构在不增加成本的条件下,综合性能显著提高,验证了方法的有效性。

关键词：混杂复合材料多目标优化机翼蒙皮非支配排序遗传算法