检索结果-南通市图书馆

Advanced primary peritoneal carcinoma:clinicopathological and prognostic factor analyses

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2008年第6期9卷 435-440页

作者： Chao ZHANG Xiao-ping li Heng CUI dan-hua SHEN li-hui WEI Gynecological Oncology Center Peking University People＇s Hospital Beijing 100044 China

Objective: To investigate the factors favoring a positive prognosis for advanced primary peritoneal carcinoma (PPC). Methods: Twenty-four cases meeting the criteria for PPC were analyzed retrospectively for the clinicopathologic profiles. Im- munohistochemistry was used to determine the expressions of p53, Top2α, Ki-67 and Her-2/neu. Then all these clinicopa- thological factors and molecular markers were correlated with the prognosis. Results: There were 15 cases of primary peritoneal serous papillary carcinoma (PPSPC), 6 cases of mixed epithelial carcinoma (MEC) and 3 cases of malignant mixed Mullerian tumor (MMMT). All patients underwent cytoreductive surgery with optimal debulking achieved in 3 cases. Among those re- ceiving first-line chemotherapy, 13 patients received the TP regimen (paclitaxel-cisplatin or carboplatin) and 7 patients received the PAC regimen (cisplatin-doxorubicin-cyclophosphamide). The median overall survival of all patients was 42 months, while the breakdown for survival time for patients with PPSPC, MMT and MEC was 44, 13 and 19 months, respectively. The expressions of p53, Top2α and Ki-67 were all demonstrated in 11 cases respectively. None showed the expression of Her-2/neu. There were significant differences in the median survival between patients with PPSPC and those with MMMT (44 months vs 13 months, P<0.05), also between patients receiving TP combination and those receiving the PAC regimen (75 months vs 28 months, P<0.05). Another significant difference in the median progression-free survival (PFS) was identified between patients with positive p53 immunostaining and those with negative p53 immunostaining (15 months vs 47 months, P<0.05), whereas age, menopausal status, residual tumor size and the other molecular factors did not significantly impact survival. Conclusion: Patients with PPC should be treated with a comprehensive management plan including appropriate cytoreductive surgery and responsive chemotherapy. Overestimating an opt

关键词： Primary peritoneal carcinoma (PPC) Cytoreductive surgery Chemotherapy Immunohistochemistry Prognosis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Two Indium(III)-based Fluorescent Metal-Organic Frameworks for Highly Sensing Fe^(3+),2,4-DNP,and TNP

引用

Chemical Research in Chinese Universities 2024年第1期40卷 119-126页

作者： WANG dan li Wen li Guanghua hua Jia liU Yunling State Key Laboratory of Inorganic Synthesis&Preparative Chemistry Jilin UniversityChangchun130012P.R.China

Two novel metal-organic frameworks(MOFs),JLU-MOF130([In(NH2−BDC)(Imi)(1H−Imi)]·DMF·H2O,NH2−H2BDC=2-aminobenzene-1,4-dicarboxylic acid,1H−Imi=1H-imidazole,DMF=N,N-dimethylformamide)and JLU-MOF131([In(1,4-NDC)(Imi)(1H−Imi)]·DMF0.5,1,4-H_(2)NDC=1,4-naphthalene-dicarboxylic acid),were ***-MOF130 features a three-dimensional(3D)architecture with a neb ***-MOF131 is characterized by a two-dimensional(2D)structure with an sql ***-MOF130 has excellent fluorescence detection performance towards Fe^(3+),2,4-dinitrophenol(2,4-DNP),and 2,4,6-trinitrophenol(TNP),but the fluorescence detection performance of JLU-MOF131 is further improved by converting NH2−H2BDC to more conjugated 1,4-H_(2)*** Stern-Volmer(SV)quenching constant(KSV)values of JLU-MOF130 sensing 2,4-DNP,TNP,and Fe^(3+)are 5.24×10^(4),4.44×10^(4),and 4.73×10^(3) L/mol,*** corresponding limit of detection(LOD)values are 1.17,1.36,and 14.59µmol/*** KSV values for JLU-MOF131 are 1.26×10^(5),9.02×10^(4),and 8.48×103 L/mol,and the corresponding LOD values are 0.35,0.42,and 3.60µmol/L,***,the emission wavelengths of the two MOFs obviously shift as the fluorescence emission intensities decrease upon the addition of 2,4-DNP and TNP,which can be applied in selective detection.

关键词： Metal-organic framework Fluorescence quenching Fe^(3+) 2 4-Dinitrophenol(2 4-DNP) 2 4 6-Trinitrophenol(TNP)

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

NUMERICAL STUDIES OF PLANETARY BOUNDARY LAYER PARAMETERIZATION SCHEMES ON SUPER TYPHOON SANBA(2012)DURING ITS INITIAL STAGE

引用

Journal of Tropical Meteorology 2018年第3期24卷 288-299页

作者： WEN Xiao-pei LONG Xiao ZHANG Shu-wen li dan-hua School of Atmospheric Sciences Lanzhou University Lanzhou 730000 China Shandong Institute of Meteorological Science Ji'nan 250031 China

The formation and development of typhoons are closely related to the disturbed low vortexes at the planetary boundary layer(PBL). The effects of five PBL parameterization schemes(PBL schemes hereinafter) on the trajectory,intensity, and distribution of physical quantities are studied using the mesoscale WRF model on Super Typhoon Sanba(2012) during its initial stage. Results show that the five PBL schemes exhibit significant different effects on the simulated intensity and path. The results simulated by QNSE and ACM2 without the Bogus method are close to the best track data in the numerical experiments. When the Bogus method is adopted, the simulated trajectories improve significantly because the initial field is close to the true data. Among the five PBL schemes, QNSE and ACM2 with the Bogus method present improved simulated path and intensity compared with the three other schemes. This finding indicates that the two schemes deal with the initial PBL process satisfactorily, especially in the formation and development of disturbed low vortexes. The differences in the treatment methods of the five PBL schemes affect the surface layer physical quantities and the middle and upper atmospheres during the middle to late periods of the *** QNSE and ACM2 present better simulation results than other schemes, they exhibit a few differences in the internal structure of the typhoon. The results simulated by MYJ are worse, and this method may be unsuitable for studying the formation and development of typhoons.

关键词： typhoon PBL parameterization schemes the Bogus method initial stage

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Laser manufacturing of spatial resolution approaching quantum limit

引用

light(Science & Applications) 2024年第3期13卷 421-428页

作者： Xiao-Jie Wang Hong-hua Fang Zhen-Ze li dan Wang Hong-Bo Sun State Key Laboratory of Precision Measurement Technology and Instruments Department of Precision InstrumentTsinghua UniversityBeijing 100084China State Key Laboratory of Integrated Optoelectronics College of Electronic Science and EngineeringJilin University2699 Qianjin StreetChangchun 130012China

Atomic and close-to-atom scale manufacturing is a promising avenue toward single-photon emitters,single-electron transistors,single-atom memory,and quantum-bit devices for future communication,computation,and sensing *** manufacturing is outstanding to this end for ease of beam manipulation,batch production,and no requirement for *** is,however,suffering from optical diffraction ***,we report a spatial resolution improved to the quantum limit by exploiting a threshold tracing and lock-in method,whereby the two-order gap between atomic point defect complexes and optical diffraction limit is surpassed,and a feature size oflications.

关键词： quantum limit resolution

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Long-wave infrared emission properties of strain-balanced InAs/In_(x)Ga_(1-x)As_(y)Sb_(1-y)type-Ⅱsuperlattice on different substrates

引用

Rare Metals 2024年第7期43卷 3194-3204页

作者： Chao Shi Xuan Fang Hong-Bin Zhao Deng-Kui Wang Xi Chen dan Fang Dong-Bo Wang Xiao-hua Wang Jin-hua li State Key Laboratory of High Power Semiconductor Lasers School of PhysicsChangchun University of Science and TechnologyChangchun 130022China State Key Laboratory of Advanced Materials for Smart Sensing China General Research Institute for Nonferrous MetalsBeijing 100088China Department of Opto-Electronic Information Science School of Materials Science and EngineeringHarbin Institute of TechnologyHarbin 150001China

High-performance type-Ⅱsuperlattices ofⅢ-Ⅴsemiconductor materials play an important role in the development and application of infrared optoelectronic *** the quality of epitaxial materials and clarifying the luminescent mechanism are of great significance for practic al applic *** this work,strain-balanced and high-quality In As/In_(x)Ga_(1-x)As_(y)Sb_(1-y)superlattices without lattice mismatch were achieved on InAs and GaSb substrates *** grown on In As substrate could exhibit higher crystal quality and surface flatness based on high-resolution X-ray diffraction(HRXRD)and atomic force microscopy(AFM)measurements'***,the strain distribution phenomenon from geometric phase analysis indicates that fluctuations of alloy compositions in superlattices on GaSb substrate are more *** addition,the optical properties of superlattices grown on different substrates are discussed *** of the difference in fluctuations of element composition and interface roughness of superlattices on different substrates,the superlattices grown on In As substrate would have higher integral intensity and narrower full-width at half maximum of long-wave infrared ***,the thermal quenching of emission intensity indicates that the superlattices grown on the In As substrate have better recombination ability,which is beneficial for increasing the operating temperature of infrared optoelectronic devices based on this type of superlattices.

关键词： Photoluminescence Alloy compositions fluctuations InAs(Sb)/In_(x)Ga_(1-x)As_(y)Sb_(1-y) Type-Ⅱsuperlattice Substrate

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The First Five Years of a Phase Theory for Complex Systems and Networks

引用

IEEE/CAA Journal of Automatica Sinica 2024年第8期11卷 1728-1743页

作者： dan Wang Wei Chen li Qiu Division of Decision and Control Systems KTH Royal Institute of TechnologyStockholm 10044Sweden Department of Mechanics and Engineering Science&the State Key Laboratory for Turbulence and Complex Systems Peking UniversityBeijing 100871China Hong Kong University of Science and Technology Hong KongChinaand also with the Southern University of Science and TechnologyShenzhen 518055China

In this paper,we review the development of a phase theory for systems and networks in its first five years,represented by a trilogy:Matrix phases and their properties;The MIMO LTI system phase response,its physical interpretations,the small phase theorem,and the sectored real lemma;The synchronization of a multi-agent network using phase *** the end,we also summarize a list of ongoing research on the phase theory and speculate what will happen in the next five years.

关键词： Consensus and synchronization matrix phases multi-agent systems phase theory sectored real lemma small phase theorem.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Improvements in properties of NdFeB magnets obtained via magnetron sputtering and thermal diffusion

引用

Journal of Rare Earths 2024年第9期42卷 1710-1716,I0003页

作者： Jin Tang Weichao huang dan li School of Electronic Engineering Guangxi University of Science and TechnologyLiuzhou545006China China Rare Earth(Guangxi)Jinyuan Rare Earth New Materials Co. Ltd.Hezhou542603China China Rare Earth Group Co. Ltd.Ganzhou341000China Center of Experimental Teaching for Common Courses Panzhihua UniversityPanzhihua617000China

The grain boundary diffusion process(GBDP) of Dy and DyAl on sintered NdFeB magnets was conducted via magnetron-sputtering deposition of Dy and DyAl films to enhance coercivity(H_(cj)),The magnetic properties,microstructure and anti-corrosion properties of Dy-surface-alloying NdFeB magnets obtained via magnetron sputtering and thermal diffusion were *** H_(cj) of the Dy_(95)Al_(5)-NdFeB magnet increases by 32.68%,while the remanence declines ***,X-ray diffraction and microstructural analysis confirm the formation of Dy-rich shells,the higher-magnetic-anisotropy field of hard(Nd_(x)Dy_(1-x))2(FeAl)_(14)B magnetic phases and an optimised grain boundary structu re,contributing to the H_(cj)enhancement of the *** elemental distribution and diffusion mechanism of the magnets are also ***,the corrosion resistance of the Dy_(95)Al_(5)-NdFeB magnet is substantially improved by enhancing the electrochemical stability and optimising the distribution and morphology of the intergranular *** findings of this study are of substantial importance in the development of low-heavy rare-earth sintered NdFeB magnets.

关键词： Magnetron sputtering NdFeB Rare earths Microstructure Magnetic property Corrosion resistance

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Microstructure and mechanical properties of Co-28Cr-6Mo-0.22C investment castings by current solution treatment

引用

China Foundry 2024年第4期21卷 369-378页

作者： Ze-yu dan Jun liu Jian-lei Zhang Yan-hua li Yuan-xin Deng Yun-hu Zhang Chang-jiang Song Center for Advanced Solidification Technology School of Materials Science and EngineeringShanghai UniversityShanghai 200444China Wuxi CastPro Precision Co. Ltd.Wuxi 214105JiangsuChina

This study examined the impact of current solution treatment on the microstructure and mechanical properties of the Co-28Cr-6Mo-0.22C alloy investment *** findings reveal that the current solution treatment significantly promotes the dissolution of carbides at a lower *** optimal conditions for solution treatment are determined as a solution temperature of 1,125°C and a holding time of 5.0 *** these parameters,the size and volume fraction of precipitated phases in the investment castings are measured as6.2μm and 1.1vol.%.The yield strength,ultimate tensile strength,and total elongation of the Co-28Cr-6Mo-0.22C investment castings are 535 MPa,760 MPa,and 12.6%,*** values exceed those obtained with the conventional solution treatment at 1,200°C for 4.0 *** findings suggest a phase transformation of M_(23)C_(6)→σ+C following the current solution treatment at 1,125°C for 5.0 *** comparison,the traditional solution treatment at 1,200°C for 4.0 h leads to the formation of M_(23)C_(6)and M_(6)C *** is noteworthy that the non-thermal effect of the current during the solution treatment modifies the free energy of both the matrix and precipitation *** modification lowers the phase transition temperature of the M_(23)C_(6)→σ+C reaction,thereby facilitating the dissolution of *** a result,the current solution treatment approach achieves carbide dissolution at a lower temperature and within a significantly shorter time when compared to the traditional solution treatment methods.

关键词： CoCrMo alloy investment castings current solution treatment microstructure mechanical property carbide

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

On the Factors Influencing the High Stretch-Flangeability of a Low-Density 1180 MPa Fe-Mn-Al-C-Nbδ-QP Steel

引用

Acta Metallurgica Sinica(English Letters) 2024年第8期37卷 1291-1300页

作者： dan‑dan Cui Peng Chen Peng‑Fei Wang Xiao‑Wu li Department of Materials Physics and Chemistry School of Materials Science and Engineeringand Key Laboratory for Anisotropy and Texture of Materials(Ministry of Education)Northeastern UniversityShenyang 110819China State Key Laboratory of Rolling and Automation Northeastern UniversityShenyang 110819China

Low-densityδ-quenching and partitioning(δ-QP)steels with excellent strength and ductility have been recently ***,there are still rare reports on the formability of δ-QP steels,which are critical for satisfying the manufacture of structural parts during the application in automotive *** the present work,an 1180 MPa Fe–Mn–Al–C–Nbδ-QP steel with a high ductility was adopted for the stretch–flangeability ***δ-QP steel was developed by separated quenching and partitioning processes.A good hole expansion ratio(HER)of 34.9±0.9%was obtained in the quenched steel,but it has been further increased to 52.2%by the tempering *** improved stretch–flangeability was attributed to the enhanced austenite stability and deformation *** the one hand,the stability of austenite was increased by carbon partitioning during tempering,which reduced crack possibility via the suppression of the fresh martensite *** the other hand,the tempering treatment released the internal stress caused by martensitic transformation and reduced the difference in strength among different phases,resulting in an increase in the resistance to crack initiation and propagation.

关键词： Hole expansion ratio Low-densityδ-quenching and partitioning(δ-QP)steel Stretch-flangeability Austenite stability Deformation uniformity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Mex-3 RNA binding family member A(MEX3A)/circMPP6 complex promotes colorectal cancer progression by inhibiting autophagy

引用

Signal Transduction and Targeted Therapy 2024年第5期9卷 2091-2103页

作者： Ri-Xin Chen Shui-dan Xu Min-hua Deng Shi-Hui Hao Jie-Wei Chen Xiao-dan Ma Wei-Tao Zhuang Jing-hua Cao Yong-Rui Lv Jin-Long lin Si-Yu li Gui-Bin Qiao dan Xie Feng-Wei Wang Department of Thoracic Surgery Guangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhou 510080China State Key Laboratory of Oncology in South China Guangdong Provincial Clinical Research Center for CancerSun Yat-sen University Cancer CenterGuangzhou 510060China Medical Research Institute Guangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhou 510080China Department of Pathology Sun Yat-sen University Cancer CenterGuangzhou 510060China

RNA-binding proteins(RBPs)-RNA networks have contributed to cancer *** RNAs(circRNAs)are considered as protein recruiters;nevertheless,the patterns of circRNA-protein interactions in colorectal cancer(CRC)are still *** bodies(PBs)formed through liquid-liquid phase separation(LLPS)are membrane-less organelles(MLOs)consisting of RBPs and *** evidence suggests a connection between PBs dynamics and cancer *** the increasingly acknowledged crucial role of RBPs and RNA in the accumulation and maintenance of MLOs,there remains a lack of specific research on the interactions between PBs-related RBPs and circRNAs in ***,we identify that MEX-3 RNA binding family member A(MEX3A),frequently upregulated in CRC tissues,predicts poorer patient *** MEX3A accelerates malignance and inhibits autophagy of CRC ***,MEX3A undergoes intrinsically disordered regions(IDRs)-dependent LLPS in the ***,circMPP6 acts as a scaffold to facilitate the interaction between MEX3A and PBs *** MEX3A/circMPP6 complex modulates PBs dynamic and promotes UPF-mediated phosphodiesterase 5A(PDE5A)mRNA degradation,consequently leading to the aggressive properties of CRC ***,CRC patients exhibiting high MEX3A expression and low PDE5A expression have the poorest overall *** findings reveal a collaboration between MEX3A and circMPP6 in the regulation of mRNA decay through triggering the PBs aggregation,which provides prognostic markers and/or therapeutic targets for CRC.

关键词： colorectal inhibiting MPP

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：