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Integrative multi-omics approaches reveal that Asian cultivated rice domestication influences its symbiotic relationship with arbuscular mycorrhizal fungi

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Pedosphere 2024年第2期34卷 315-327页

作者： Lei tian Jilin WANG Hongping CHEN Weiqiang li Lam-Son Phan TRAN Chunjie tian Key Laboratory of Mollisols Agroecology State Key Laboratory of Black Soils Conservation and UtilizationNortheast Institute of Geography and AgroecologyChinese Academy of SciencesChangchun 130102China Rice Research Institute Jiangxi Academy of Agricultural SciencesNanchang 330200China Institute of Genomics for Crop Abiotic Stress Tolerance Department of Plant and Soil ScienceTexas Tech UniversityLubbock TX 79409USA

Potential changes in the symbiotic relationship between rice(Oryza sativa)and microorganisms have occurred during the domestication of Asian cultivated rice(***)from common wild rice(Oryza rufipogon)and in response to global climate change,along with evolving adaptations to the *** potential genes may express differently or dominate the symbiotic relationships between arbuscular mycorrhizal fungi(AMF)and plants,which may be beneficial to rice *** date,research on this important topic has been *** this study,we aimed to examine the symbiotic relationships of Asian common wild and cultivated rice species with *** conducting a comparative metagenomic analysis of the rhizospheres of wild and cultivated rice species,we identified differences in Rhizophagus intraradices-related genes associated with wild and cultivated rice,as well as functional genes of ***,we obtained root-related genes associated with AMF from transcriptome data of rice *** results collectively suggest that ***-related genes in the rhizosphere of wild rice may be more conducive to its ***,bacteria from the Nitrosomonadaceae and Nitrospiraceae families identified in the rhizosphere of wild rice exhibited positive correlations with ***-related genes with protein identifiers 1480749 and1871253,which may indicate that nitrobacteria can enhance the functions of *** in association with wild ***,in a case study using comparative transcriptome analysis of root samples obtained from ***-inoculated wild and cultivated rice plants,we found significantly higher expression levels of the strigolactone pathway-related genes DWARF3(D3)and DWARF14(D14)in ***-inoculated common wild rice than in ***-inoculated cultivated *** study provides a theoretical basis for identifying the effects of domestication on mycorrhizal symbiosis-related genes,which could be promoted in wi

关键词： Rhizophagus intraradices root-related gene symbiotic effect strigolactone wild rice

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Root cause of corrosion failure of tin coating on wire clamp in marine atmosphere

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Journal of Iron and Steel Research International 2024年第4期31卷 998-1014页

作者： zhen Zhong Wang-yan Ly Teng-yuan liu Yi Xie Yang Yang zhen-zhu Wang Deng-ke li Xiao-bo li Tang-qing Wu School of Materials Science and Engineering Xiangtan UniversityXiangtan 411105HunanChina Electric Power Research Institute of Guangdong Power Grid Co. Ltd.Guangzhou 510080GuangdongChina Shenyang National L aboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016LiaoningChina School of Materials Science and Engineering.University of Science and Technology of China Shenyang 110016LiaoningChina Electric Power Research Institute State Grid Hunan Electric Power CompanyChangsha 410007HunanChina School of Mechanical Engineering and Mechanics Xiangtan UniversityXiangtan 411105HunanChina School of Information Science and Engineering Changsha Normal UniversityChangsha 410199HunanChina

The failure cause of a tinned copper wire clamp in marine atmosphere was studied systematically by X-ray photoelectron spectroscopy,scanning electron microscopy with energy dispersive spectroscopy and electrochemical *** main components of the green rust on the surface of the damaged wire clamp are SnO_(2),CuO,Cu_(2)Cl(OH)_(3) and CuCO(OH)_(2).Much of green rust distributes at the platform edge along the axial direction on the crimp connection,and severe corrosion and corrosion pits occur at the platform edge zone along the axial *** enriching Cl-at the marine atmosphere and the existing O_(2) in air collectively enhance the corrosion process of the tin coating and the copper *** element model results show that the residual stress and strain of the tin coating are the largest at the platform edge along the axial direction on the crimp connection,and the corresponding electrode potential of the tin coating at this zone drops *** above results indicate that the residual strain increases the driving force of the corrosion electrochemical reactions and accelerates the corrosion rate and the pit corrosion of the tin coating at this zone.

关键词： Tin coating Marine atmosphere Residual strain-Chloride ion Corrosion failure

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Prognostic nomograms for young breast cancer:A retrospective study based on the SEER and METABRIC databases

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Cancer Innovation 2024年第6期3卷 86-99页

作者： Yongxin li Xinlong Tao Yinyin Ye Yuyao Tang zhengbo Xu Yaming tian zhen liu Jiuda Zhao Breast Disease Diagnosis and Treatment Center of Affiliated Hospital of Qinghai University&Affiliated Cancer Hospital of Qinghai University XiningQinghaiChina Qinghai University XiningQinghaiChina Department of Imaging Affiliated Hospital of Qinghai UniversityXiningQinghaiChina

Background:Young breast cancer(YBC)is a subset of breast cancer that is often more aggressive,but less is known about its *** this study,we aimed to generate nomograms to predict the overall survival(OS)and breast cancer‐specific survival(BCSS)of YBC ***:Data of women diagnosed with YBC between 2010 and 2020 were obtained from the Surveillance,Epidemiology,and End Results(SEER)*** patients were randomly allocated into a training cohort(n=15,227)and internal validation cohort(n=6,526)at a 7:3 *** the Cox regression models,significant prognostic factors were identified and used to construct 3‐,5‐,and 10‐year nomograms of OS and *** from the Molecular Taxonomy of Breast Cancer International Consortium(METABRIC)database were used as an external validation cohort(n=90).Results:We constructed nomograms incorporating 10 prognostic factors for OS and *** nomograms demonstrated strong predictive accuracy for OS and BCSS in the training cohort,with C‐indexes of 0.806 and 0.813,*** calibration curves verified that the nomograms have good prediction *** curve analysis demonstrated their practical clinical value for predicting YBC patient survival ***,we provided dynamic nomograms to improve the operability of the *** risk stratification ability assessment also showed that the OS and BCSS rates of the low‐risk group were significantly better than those of the high‐risk ***:Here,we generated and validated more comprehensive and accurate OS and BCSS nomograms than models previously developed for *** nomograms can help clinicians evaluate patient prognosis and make clinical decisions.

关键词： breast cancer‐specific survival nomogram overall survival prognostic model young breast cancer

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Numerical Study on Reduction in Aerodynamic Drag and Noise of High-Speed Pantograph

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Computer Modeling in Engineering & Sciences 2024年第5期139卷 2155-2173页

作者： Deng Qin Xing Du tian li Jiye Zhang State Key Laboratory of Rail Transit Vehicle System Southwest Jiaotong UniversityChengdu610031China School of Electrical Engineering Southwest Jiaotong UniversityChengdu610031China

Reducing the aerodynamic drag and noise levels of high-speed pantographs is important for promoting environmentally friendly,energy efficient and rapid advances in train *** computational fluid dynamics theory and the K-FWH acoustic equation,a numerical simulation is conducted to investigate the aerodynamic characteristics of high-speed pantographs.A component optimization method is proposed as a possible solution to the problemof aerodynamic drag and noise in high-speed *** results of the study indicate that the panhead,base and insulator are the main contributors to aerodynamic drag and noise in high-speed ***,a gradual optimization process is implemented to improve the most significant components that cause aerodynamic drag and *** optimizing the cross-sectional shape of the strips and insulators,the drag and noise caused by airflow separation and vortex shedding can be *** aerodynamic drag of insulator with circular cross section and strips with rectangular cross section is the *** insulators and optimizing the chamfer angle and height of the windward surface of the strips can improve the aerodynamic performance of the *** addition,the streamlined fairing attached to the base can eliminate the complex flow and shield the radiated *** contrast to the original pantograph design,the improved pantograph shows a 21.1%reduction in aerodynamic drag and a 1.65 dBA reduction in aerodynamic noise.

关键词： High-speed pantograph aerodynamic drag aerodynamic noise reduction optimizing

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Recent progress of in situ/operando characterization techniques for electrocatalytic energy conversion reaction

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Chinese Chemical Letters 2024年第9期35卷 92-101页

作者： Zhao li Huimin Yang Wenjing Cheng lin tian School of Materials and Chemical Engineering Xuzhou University of TechnologyXuzhou 221018China University and College Key Lab of Natural Product Chemistry and Application in Xinjiang School of Chemistry and Environmental ScienceYili Normal UniversityYining 835000China

Catalysts can significantly promote the reaction dynamics and are therefore considered crucial components for achieving high electrochemical energy conversion ***,the active sites of the catalysts,particularly for nano-level and atomic-level catalysts commonly undergo reconstruction under practical ***,obtaining an in-depth and systematic understanding on the real active sites through in situ/operando characterization techniques is a prerequisite for establishing the structureperformance relationship and guiding the future design of more efficient ***,we summarize the recent progress of in situ/operando characterization techniques for identifying the nature of active sites of electrocatalysts when used in electrocatalytic energy conversion ***,our focus lies in the fundamental principles of various in situ/operando characterization techniques,with particular emphasis on their applications for electrocatalytic *** that,the challenges and perspective insights are also added in the final section to highlight the future direction of this important field.

关键词： In situ techniques Electrocatalysis Active sites Energy conversion

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A muon high-resolution pseudorange measurement method: Application to muon navigation in confined spaces

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Chinese Journal of Aeronautics 2024年第4期37卷 391-404页

作者： Haoyang li Chunxi ZHANG Xingming FAN Longjie tian tianqi li Yang PANG Yanqiang YANG Institute of Optics and Electronics School of Instrumentation Science and Optoelectronics EngineeringBeihang UniversityBeijing 100191China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China

Confined spaces such as polar regions, deep earth and deep ocean are crucial navigation scenarios where traditional navigation techniques have difficulty in obtaining external signals for positioning. The cosmic ray muons, which carry the spatial and energetic information, are easy to penetrate these confined spaces. Therefore, the unique muon characteristic provides a new perspective to estimate detector position, which can be considered using in confined spaces *** this paper, a well-developed theory of muon navigation is established by combining a muon pseudorange measurement method. Moreover, an Equivalent Velocity Calculation Model(EVCM)and a Muon Sequence Matching Technology(MSMT) are proposed. The first model corrects flight pseudorange error caused by the relativistic energy loss and the second technology compensates the random error in pseudorange measurement. Further, a series of simulations are performed to analyze the muon events number which can be received by detector in different scenarios with the variations of zenith angle, detector area, varied detector plates gap, and muon flight ***, the simulation results demonstrate that the muon navigation update rate every 10 minutes can reach 5.989 in confined spaces at 100 m, and further pseudorange error analysis indicates that the meter-level positioning accuracy can be acquired. Finally, we construct a muon coincidence measurement scheme and verify that the laws of the muon positioning system for high-energy muons are consistent with the simulation results.

关键词： Muon navigation Cosmic ray muons Muon detection technology Muon transmission technology Pseudorange measurement

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Reevaluation by the CRISPR/Cas9 knockout approach revealed that multiple pluripotency-associated lncRNAs are dispensable for pluripotency maintenance while Snora73a/b is essential for pluripotency exit

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Science China(life Sciences) 2024年第10期67卷 2198-2212页

作者： zhen li Xuefei li Jingxia lin Yangming Wang Huiqing Cao Jiajian Zhou Institute of Molecular Medicine College of Future TechnologyPeking UniversityBeijing 100871China Dermatology Hospital Southern Medical UniversityGuangzhou 510091China Beijing Advanced Center of RNA Biology(BEACON) Peking UniversityBeijing 100871China

Many long noncoding RNAs(lncRNAs)have been identified through siRNA-based screening as essential regulators of embryonic stem cell(ESC)***,the biological and molecular functions of most lncRNAs remain ***,we employed CRISPR/Cas9-mediated knockout technology to explore the functions of 8 lncRNAs previously reported to promote pluripotency in mouse ***,all of these lncRNAs were dispensable for pluripotency maintenance and proliferation in mouse ESCs when disrupted individually or in ***-cell transcriptomic analysis also showed that the knockout of these lncRNAs has a minimal impact on pluripotency gene expression and cell *** further showed that several small hairpin RNAs(shRNAs)previously used to knock down lncRNAs caused the downregulation of pluripotency genes in the corresponding lncRNA-knockout ESCs,indicating that off-target effects likely responsible for the pluripotency defects caused by these ***,linc1343-knockout and linc1343-knockdown ESCs failed to form cystic structures and exhibited high expression of pluripotency genes during embryoid body(EB)*** reintroducing RNA products generated from the linc1343 locus,we found that two snoRNAs,Snora73a and Snora73b,but not lncRNAs,could rescue pluripotency silencing defects during EB differentiation of linc1343 knockout *** results suggest that the 8 previously annotated pluripotency-regulating lncRNAs have no overt functions in conventional ESC culture;however,we identified snoRNA products derived from an annotated lncRNA locus as essential regulators for silencing pluripotency genes.

关键词： long noncoding RNAs embryonic stem cells CRISPR/Cas9 snoRNAs stem cell differentiation

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Multi-distortion suppression for neutron radiographic images based on generative adversarial network

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Nuclear Science and Techniques 2024年第4期35卷 176-188页

作者： Cheng-Bo Meng Wang-Wei Zhu zhen Zhang Zi-Tong Wang Chen-Yi Zhao Shuang Qiao tian Zhang School of Physics Northeast Normal UniversityChangchun 130024China

Neutron radiography is a crucial nondestructive testing technology widely used in the aerospace,military,and nuclear ***,because of the physical limitations of neutron sources and collimators,the resulting neutron radiographic images inevitably exhibit multiple distortions,including noise,geometric unsharpness,and white ***,these distortions are particularly significant in compact neutron radiography systems with low neutron ***,in this study,we devised a multi-distortion suppression network that employs a modified generative adversarial network to improve the quality of degraded neutron radiographic *** neutron radiographic image datasets with various types and levels of distortion were built for the first time as multi-distortion suppression ***,the coordinate attention mechanism was incorporated into the backbone network to augment the capability of the proposed network to learn the abstract relationship between ideally clear and degraded *** experiments were performed;the results show that the proposed method can effectively suppress multiple distortions in real neutron radiographic images and achieve state-of-theart perceptual visual quality,thus demonstrating its application potential in neutron radiography.

关键词： Neutron radiography Multi-distortion suppression Generative adversarial network Coordinate attention mechanism

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Hole-Transporting Materials with Rational Combination of Pyridine and Dibenzo[a,c]phenazine as Electron Acceptor for Dopant-Free Perovskite Solar Cells

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Chinese Journal of Chemistry 2024年第10期42卷 1100-1106页

作者： Weidong ling Fei Wu Wentao Yuan linna Zhu Qianqian li zhen li Hubei Key Lab on Organic and Polymeric Opto-Electronic Materials Department of ChemistryWuhan UniversityWuhanHubei 430072China Chongqing Key Laboratory for Advanced Materials and Technologies of Clean Energy Faculty of Materials&EnergySouthwest UniversityChongqing400715China TaiKang Center for life and Medical Sciences Wuhan UniversityWuhanHubei 430072China

Perovskite solar cells(PSCs)have been proven to be a promising option for photovoltaic *** the aim to achieve efficient and stable PSCs,it is essential to explore dopant-free hole-transporting materials(HTMs)with high hole ***,HTMs bearing electron donor(D)-electron acceptor(A)-electron donor(D)structures have been constructed with strong intramolecular charge transfer(ICT)effect,based on rational combination of dibenzo[a,c]phenazine and pyridine as electronic acceptors and anchoring groups to perovskite ***,high hole mobility(7.31×10^(-5) cm^(2)·V^(-1)·s^(-1))and photoelectric conversion efficiency(20.45%)have been achieved by dopant-free DPyP-based *** afforded an efficient way to design HTMs with high hole mobility by adjustment of molecular configurations and electronic property of conjugated systems.

关键词： Perovskite solar cell Charge transfer Donor-acceptor systems Energy conversion Hole mobility

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Iridoids modulate inflammation in diabetic kidney disease: A review

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Journal of Integrative Medicine 2024年第3期22卷 210-222页

作者： Tong-yi Zhou Na tian liu li Rong Yu The First Clinical College of Chinese Medicine Hunan University of Chinese MedicineChangsha 410208Hunan ProvinceChina Hunan Provincial Key Laboratory of Translational Research in Traditional Chinese Medicine Prescriptions and zheng Changsha 410208Hunan ProvinceChina

In recent years,preclinical research on diabetic kidney disease (DKD) has surged to the forefront of scientific and clinical *** has become a pervasive complication of type 2 *** the complexity of its etiology and pathological mechanisms,current interventions,including drugs,dietary modifications,exercise,hypoglycemic treatments and lipid-lowering methods,often fall short in achieving desired therapeutic ***,primarily derived from the potent components of traditional herbs,have been the subject of long-standing *** data suggest that iridoids possess notable renal protective properties;however,there has been no summary of the research on their efficacy in the management and treatment of *** article consolidates findings from in vivo and in vitro research on iridoids in the context of DKD and highlights their shared anti-inflammatory activities in treating this ***,it explores how certain iridoid components modify their chemical structures through the regulation of intestinal flora,potentially bolstering their therapeutic *** review provides a focused examination of the mechanisms through which iridoids may prevent or treat DKD,offering valuable insights for future research endeavors.

关键词： Diabetic kidney disease Iridoids Gut-kidney axis Traditional Chinese medicine monomer Inflammation

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