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A Tentative Evaluation of "The Three-step Method" In Teaching English Phonetics In Class

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郴州师专学报 1994年第4期15卷 10-14,22页

作者： li li-jun

The reform into the method of teaching English phonetics still remains a weat ling, This paper, deals with some efficacious attempts made in the classroom teaching of the English phonetics from the Three-step Method :

关键词：语音学教学方法英语语法结构

Reaction mechanism of molten Na OH decomposing Zn_2SiO_4 in willemite

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Journal of Central South University 2015年第4期22卷 1227-1231页

作者：赵昌明翟玉春张崇民李军丽李胜利 School of Materials and Metallurgy University of Science and Technology Liaoning School of Materials and Metallurgy Northeastern University

Based on the existing form of Zn2 Si O4 in willemite, the chemical precipitation method was used to synthesize Zn2 Si *** the orthogonal experimentation, the reaction conditions of melten Na OH decomposing Zn2 Si O4 were optimized, and the optimal experimental conditions include reaction temperature of 400 °C, reaction time of 4 h, and alkaline-to-ore molar ratio of 20:*** on the optimized experiment, on-line detection for the alkali leaching was made by using Raman spectroscopy; XRD was used to analyze the structure of water leaching residue, to explore the reaction mechanism of Na OH decomposing Zn2 Si O4. The results show that during the reaction process, the Si — O bond in Si O4 is destroyed, and the Na OH inserts itself into the silicate lattice,producing an immediate Na2 Zn Si O4 product. After the alkali leaching process, Zn2+ can be separated from the Si O4 array, which can be released out of the silicate in the form of ZnO.

关键词： Raman spectroscopy Zn2SiO4 alkali melting reaction mechanism

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氧化锡纳米结构的制备及光致发光性能

功能材料 2013年第9期44卷 1269-1271,1276页

作者：李立珺西安邮电大学电子工程学院陕西西安710121

利用热蒸发法成功制备出了两种氧化锡纳米结构。利用X射线衍射法、拉曼光谱、扫描电子显微镜和透射电子显微镜对两种纳米结构的晶格结构和表面形貌做了详细分析,结果表明所制纳米结构为金红石型氧化锡晶体结构,氧化锡纳米结构的形貌与... 详细信息

利用热蒸发法成功制备出了两种氧化锡纳米结构。利用X射线衍射法、拉曼光谱、扫描电子显微镜和透射电子显微镜对两种纳米结构的晶格结构和表面形貌做了详细分析,结果表明所制纳米结构为金红石型氧化锡晶体结构,氧化锡纳米结构的形貌与实验中所用的源材料有着很大的关系。以氧化锡和碳粉的混合物为源,制备出的纳米线长且直,直径在50～200nm之间,以氧化亚锡和碳粉为源,制备出的纳米结构短且多弯折,直径在150nm左右。研究了所制氧化锡纳米材料的室温光致发光性能,发光峰位于590、630和677nm处。

关键词：氧化锡纳米结构热蒸发法 X射线衍射光致发光

Low Correspondence of EGFR Mutations in Tumor Tissue And Paired Serum of Non-Small-Cell Lung Cancer Patients

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Chinese Journal of Cancer Research 2010年第1期22卷 27-31页

作者： Guo-hong Song,jun Ren,li-jian Zhang,li-jun Di, Yan-hua Yuan,Jing Yu,jun Jia Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education) Department of Medical Oncology,Peking University School of Oncology,Beijing Cancer Hospital & Institute,Beijing 100142,China Key laboratory of Carcinogenesis and Translational Research (Ministry of Education) Department of Medical Oncology Peking University School of Oncology Beijing Cancer Hospital & Institute Beijing China

Objective： Epidermal growth factor receptor （EGFR） mutations are strong determinants of tumor response to EGFR tyrosine kinase inhibitors in non-small-cell lung cancer （NSCLC） patients. The aim of this study was to evaluate the correspondence between EGFR mutations in non-small-cell lung cancer tissues and in circulating DNA. Methods： The research was conducted in 50 non-small-cell lung cancer patients who had undergone curative surgery, and in whom both serum and neoplastic tissues were available. Meanwhile sera of 33 cases of advanced NSCLC patients were also analyzed. DNA were extracted from each sample. Mutations of EGFR in exonl8-21 were examined by PCR amplification method and direct sequencing. Results： EGFR mutations were detected in 15 （30%） of 50 neoplastic tissue samples, 6 cases were in-frame deletion del E746-A750 in exonl9, 9 cases were substitution in exon 21 （all were L858R except one was L861Q）, but no mutated DNA resulted in paired serum circulating DNA samples of 50 resectable patients. As the 33 advanced NSCLC patients, EGFR mutations were detected in only 2 serum circulating DNA samples, all were L858R mutation in exon 21. Conclusion： These data indicated that it was difficult to identify EGFR mutations in circulating DNA of NSCLC patients. The use of EGFR mutation in serum as a clinical method for decision making of TKI therapy is unsatisfactory.

关键词： Circulating DNA Epidermal growth factor receptor (EGFR) Mutation Non-small-cell lung cancer (NSCLC)

Roles of sulfonylurea receptor 1 and multidrug resistance protein 1 in modulating insulin secretion in human insulinoma

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Hepatobiliary & Pancreatic Diseases International 2011年第1期10卷 88-94页

作者： Cheng-Jiang li,Hua-li Zhou,jun li,Hong-Tian Yao,Rong Su and Wen-Peng li Department of Endocrinology(li CJ,Zhou HL and li WP),Department of Pathology,and Key Laboratory of Multi-organ Transplantation of Ministry of Public Health,First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310003,China Department of Endocrinology First Affiliated Hospital Zhejiang University School of Medicine Hangzhou 310003 China Department of Pathology First Affiliated Hospital Zhejiang University School of Medicine Hangzhou 310003 China Key Laboratory of Multi-organ Transplantation of Ministry of Public Health First Affiliated Hospital Zhejiang University School of Medicine Hangzhou 310003 China

BACKGROUND:Sulfonylurea receptor 1(SUR1)and multidrug resistance protein 1(MRP1)are two prominent members of multidrug resistance proteins associated with insulin secretion. The aims of this study were to investigate their expression in insulinomas and their sole and synergistic effects in modulating abnormal insulin secretion. METHODS:Fasting glucose,insulin and C-peptide were measured in 11 insulinoma patients and 11 healthy controls. Prolonged oral glucose tolerance tests were performed in 6 insulinoma *** content,SUR1 and MRP1 were detected in 11 insulinoma patients by immunohistochemistry. SUR1 and MRP1 were also detected in 6 insulinoma patients by immunofluorescence. RESULTS:Insulinoma patients presented the typical demons-trations of Whipple’s *** glucose of each insulinoma patient was lower than 2.8 mmol/L,and simultaneous insulin and C-peptide were increased in insulinoma patients. Prolonged oral glucose tolerance tests showed that insulin secretion in insulinoma patients were also stimulated by high *** and immunofluorescence staining showed that SUR1 increased,but MRP1 decreased in insulinoma compared with the adjacent islets. CONCLUSIONS:The hypersecretion of insulin in insulinomas might be,at least partially,due to the enrichment of SUR1. In contrast,MRP1,which is down-regulated in insulinomas, might reflect a negative feedback in insulin secretion.

关键词： sulfonylurea receptor 1 multidrug resistance protein 1 ATP-binding cassette transporters insulinoma insulin secretion

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含热诱发扰动的挠性卫星L_1自适应控制

宇航学报 2015年第1期36卷 68-75页

作者：李丽君袁军北京控制工程研究所北京100190 空间智能控制技术重点实验室北京100190

为了揭示挠性帆板的热诱发运动机理及其对卫星本体姿态机动的影响,采用拉格朗日能量法建立了主刚体带挠性梁模型受到突加热流时系统的动力学模型,分析了帆板热诱发运动的特性。假设系统的模型参数未知,设计了L1自适应控制器,仅卫星的姿... 详细信息

为了揭示挠性帆板的热诱发运动机理及其对卫星本体姿态机动的影响,采用拉格朗日能量法建立了主刚体带挠性梁模型受到突加热流时系统的动力学模型,分析了帆板热诱发运动的特性。假设系统的模型参数未知,设计了L1自适应控制器,仅卫星的姿态角和姿态角速度作为反馈量,将帆板热致振动和变形作为未建模动力学特性,实现卫星考虑帆板热扰动力矩的快速姿态机动控制。数值仿真结果表明,环境温度突然变化引起的帆板运动包括准静态变形和振动两部分,同时引起的姿态误差也包括常值偏差和姿态振动,所设计的控制器在系统考虑热引起的扰动时仍可以有效地实现卫星的快速姿态机动,且系统各阶挠性模态稳定,参数估计收敛。

关键词：姿态机动 L1自适应控制热致振动挠性帆板动力学建模

Factors predisposing to severe acute pancreatitis:evaluation and prevention

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World Journal of Gastroenterology 2003年第5期9卷 1102-1105页

作者： Bei Sun Ha-li li Yue Gao jun Xu Hong-Chi Jiang Department of General Surgery,First Clinical Hospital,Harbin Medical University,Harbin 150001,China Department of General Surgery First Clinical Hospital Harbin Medical University China. sunbei70@***

AIM: To analyze factors predisposing to the infections associated with severe acute pancreatitis (SAP) and to work out ways for its ***: Total 208 cases of SAP treated in this hospital from Jan. 1980 to Dec. 2001 were retrospectively ***: Statistical difference in the incidence of the aforementioned infections was found between the following pairs: between the groups of bloody or non-bloody ascites,paralytic ileus lasting shorter or longer than 5 days, Ranson scores lower or higher than 5, hematocrit lower or higher than 45 %, CT Balthazar scores lower or higher than 7 and between 1980.1-1992.6 or 1992.7-2001.12 admissions (χ2＞3.84, P＜0.05), while no statistical difference was established between the groups of biliogenic and nonbiliogenic pancreatitis, serum amylase ＜200 U/L and ≥200U/L, serum calcium ＜2 mmol/L and ≥ 2 mmol/L or groups of total parenteral nutrition shorter or longer than 7 days (χ2＜3.84, P＞0.05).CONCLUSION: Occurrence of infection in patients with SAP is closely related with bloody ascites, paralytic ileus ≥5 days, Ranson scores ≥5, hematocrit ≥45 % and CT Balthazar Scores ≥7, but not with pathogens, serum calcium and total parenteral nutrition (TPN). Comprehensive prevention of pancreatic infection and practice of individualized therapy contribute to reducing the incidence of infection.

关键词：急性胰腺炎早期诊断危险因素感染血性腹水

A Positive Comparative Study of Regional Human Resources Quality

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Systems Science and Systems Engineering 2000年第2期10卷 185-193页

作者： YUAN li\|jing,\ li jun\|jie College of Management, Zhejiang University, Hangzhou 310027, China

This thesis appraises the human resources in developed regions, relatively developed regions, moderately developed regions and underdeveloped regions in China by means of comprehensive fuzzy assessment of human resources quality. Then the interrelationship between regional economic development and human resources quality is analysed. The results can be of some value for decision making.

关键词： regional human resources quality economic development/growth comparative research

双排桩支护结构中圈梁空间效应的数值模拟分析

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北京理工大学学报 2012年第5期32卷 446-449页

作者：李立军太原理工大学建筑与土木工程学院山西太原030024

针对深基坑双排桩支护结构中圈梁的空间效应问题,利用FLAC3D模拟计算一深基坑双排桩支护工程在设置圈梁的情况下,其不同位置处桩顶位移与弯矩变化.结果发现:基坑坑角的桩顶位移明显小于中部桩顶位移,越到中部桩顶位移越大;将计算结果与... 详细信息

针对深基坑双排桩支护结构中圈梁的空间效应问题,利用FLAC3D模拟计算一深基坑双排桩支护工程在设置圈梁的情况下,其不同位置处桩顶位移与弯矩变化.结果发现:基坑坑角的桩顶位移明显小于中部桩顶位移,越到中部桩顶位移越大;将计算结果与现场实测资料对比表明,两者变化规律具有较好的一致性.研究表明,支护排桩与圈梁之间有较好的协同作用,圈梁对支护桩的变形和内力均有一定的影响,限制了排桩的位移和弯矩,越靠近基坑坑角其空间效应越明显.在双排桩支护结构体系设计中应考虑圈梁的空间效应,为优化设计提出建议.

关键词：双排桩圈梁空间效应位移 FLAC3D