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宇宙射线对铁陨石中Cr同位素的影响

宇宙射线对铁陨石中Cr同位素的影响

“CCG+广义斯科伦项理论”视角下汉语并列句的量词辖域分析

2015中国地球科学联合学术年会

作者：刘佳秦礼萍夏九星 ingo leya 中国科学技术大学地球与空间科学学院 Space Research and Planetology University of Berne

天体样品在从母体分离到进入地球大气期间会受到宇宙射线的辐射,这些样品与宇宙射线中的高能粒子以及之后产生的二次粒子通过散裂反应和热中子及超热中子捕获反应改变了样品中原有的元素和同位素组成,这些由于宇宙射线辐射而产生的核素... 详细信息

天体样品在从母体分离到进入地球大气期间会受到宇宙射线的辐射,这些样品与宇宙射线中的高能粒子以及之后产生的二次粒子通过散裂反应和热中子及超热中子捕获反应改变了样品中原有的元素和同位素组成,这些由于宇宙射线辐射而产生的核素被称为宇宙成因核素。人们对于宇宙成因核素的

关键词：同位素铁陨石

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广西科技师范学院学报 2024年第1期39卷 28-36页

作者：朱乐亚南华大学语言文学学院湖南衡阳421001

融入广义斯科伦项理论的组合范畴语法可对汉语并列句中NP和NP间的量词辖域关系作出解释。首先,本研究将汉语量化并列句分成典型量化并列句和非典型量化并列句,然后侧重分析典型量化并列句中NP和NP间的量词辖域关系,并给出合乎语句原义... 详细信息

融入广义斯科伦项理论的组合范畴语法可对汉语并列句中NP和NP间的量词辖域关系作出解释。首先,本研究将汉语量化并列句分成典型量化并列句和非典型量化并列句,然后侧重分析典型量化并列句中NP和NP间的量词辖域关系,并给出合乎语句原义的完整推演图。在典型量化并列句中,本研究主要考察体词性量化并列句和动词性量化并列句中NP和NP间的量词辖域关系。研究结果发现,融入广义斯科伦项理论的组合范畴语法聚焦于量词属性的描述,这能对并列句和量词辖域间的关系进行合理地刻画。

关键词：组合范畴语法广义斯科伦项理论量词辖域

“CCG+广义斯科伦项理论”视域下汉语被动句的量词辖域分析

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郑州航空工业管理学院学报（社会科学版） 2024年第5期43卷 97-102页

作者：朱乐亚南华大学语言文学学院湖南衡阳421001

在融入广义斯科伦项理论的CCG框架内分析汉语被动句中量化名词词组间的辖域互动关系,并尝试论证汉语量化被动句的辖域歧义本质上是词汇歧义。首先,将汉语量化被动句划分成两个子类:汉语量化长被动句和汉语量化短被动句。然后在“CCG+广... 详细信息

在融入广义斯科伦项理论的CCG框架内分析汉语被动句中量化名词词组间的辖域互动关系,并尝试论证汉语量化被动句的辖域歧义本质上是词汇歧义。首先,将汉语量化被动句划分成两个子类:汉语量化长被动句和汉语量化短被动句。然后在“CCG+广义斯科伦项理论”框架内对各类量化被动句的量词辖域现象做出解释。在量化长被动句中,主要分析有界量化长被动句和无界量化长被动句中量词间的辖域互动现象。在量化短被动句中,主要探讨有界量化短被动句和无界量化短被动句中量化名词词组间的辖域互动现象。研究结果发现,汉语量化被动句存在量词辖域歧义性。

关键词：组合范畴语法广义斯科伦项理论汉语被动句量词辖域

基于动态离散模型的机场ADS-B攻击威胁影响研究

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电光与控制 2024年第7期31卷 27-35,52页

作者：白洁王布宏田继伟王振曾乐雅阳勇空军工程大学信息与导航学院西安710000

随着航空业信息技术的发展,空中交通管制系统面临着多种网络攻击的威胁。广播式自动相关监视(ADS-B)系统因其明文广播的数据传输方式,存在着被网络攻击的安全问题。依据“等待降落-降落-停泊-排队起飞-起飞”的航班运行全流程,建立了WL... 详细信息

随着航空业信息技术的发展,空中交通管制系统面临着多种网络攻击的威胁。广播式自动相关监视(ADS-B)系统因其明文广播的数据传输方式,存在着被网络攻击的安全问题。依据“等待降落-降落-停泊-排队起飞-起飞”的航班运行全流程,建立了WLPQD动态离散模型,研究机场流量和航班延误。模型引入了系统冗余能力、处理速率等参数,模拟了攻击场景;通过受影响飞机数量和延误时间等指标研究了机场航班延误的传播影响。模型展示了ADS-B消息注入攻击对降落、起飞航班造成的延误,提出了两种攻击缓解方法。结果表明,延误规模的大小与攻击强度呈现正相关,且攻击对起飞航班的延误影响更大;提升对“幽灵飞机”和合法飞机的处理速率都可提升机场系统的抗毁性,但前者对提升机场系统冗余能力的效果更加显著。所做研究为机场系统抵御网络攻击、增强抗毁性提供了决策分析的参考依据。

关键词： ADS-B 动态离散模型网络安全航班延误

Discovery of Extended Structure Around Open Cluster COIN-Gaia 13 Based on Gaia EDR3

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Research in Astronomy and Astrophysics 2022年第5期22卷 199-207页

作者： leya Bai Jing Zhong Li Chen Jing Li Jinliang Hou School of Physics and Astronomy China West Normal UniversityNanchong 637002China Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China School of Astronomy and Space Science University of Chinese Academy of SciencesBeijing 100049China

COIN-Gaia 13 is a newly discovered open cluster revealed by Gaia DR2 *** is a nearby open cluster with a distance of about 513 *** with the five-dimensional astrometric data of Gaia EDR3 with higher accuracy,we use the membership assignment algorithm(pyUPMASK)to determine the membership of COINGaia 13 in a large extended spatial *** cluster has 478 identified candidate *** obtaining reliable cluster members,we further study its basic properties and spatial *** results show that there is an obvious extended structure of the cluster in the X-Y *** elongated structure is distributed along the spiral arm,and the whole length is about 270 *** cluster age is 250 Myr,the total mass is about 439 M_(⊙) and the tidal radius of the cluster is about 11 *** more than half of member stars(352 stars)are located outside twice the tidal radius,it is suspected that this cluster is undergoing the dynamic dissolution ***,the spatial distribution and kinematic analysis indicate that the extended structure in COIN-Gaia 13 is more likely to be caused by differential rotation of the Galaxy.

关键词： (Galaxy:)open clusters and associations individual (COIN-Gaia 13)-stars kinematics and dynamicsmethods data analysis

基于顶空固相微萃取-气相色谱-嗅闻仪-质谱仪结合气味活力值鉴定槟榔香六堡茶关键香气物质

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食品与发酵工业 2024年第8期50卷 271-277页

作者：陈国和胡腾飞王乐涯欧行畅李勤黄建安刘仲华王超湖南农业大学茶学教育部重点实验室湖南长沙410128 国家植物功能成分利用工程技术研究中心湖南长沙410128 湖南省植物功能成分利用协同创新中心湖南长沙410128

为了探究六堡茶槟榔香风味构成的关键香气物质,该研究采用顶空固相微萃取(headspace solid-phase microextraction,HS-SPME)结合气相色谱-嗅闻仪-质谱仪(gas chromatography-olfactometry-mass spectrometry,GC-O-MS)和气味活力值(odor activity value,OAV)分析槟榔香六堡茶气味化合物组成,筛选其中的关键香气物质。经GC-O-MS分析,从槟榔香六堡茶样品中嗅闻、鉴定出37种气味化合物,气味强度(odor intensity,OI)中等及以上的化合物为19种,其中二氢-β-紫罗兰酮、β-紫罗兰酮、β-芳樟醇、雪松醇和1,2,3-三甲氧基苯展现出了较高的香气强度。在GC-O-MS分析的基础上,采用OAV法进一步分析,发现槟榔香六堡茶中OAV≥1的气味化合物有18种,其中,二氢-β-紫罗兰酮、β-紫罗兰酮、苯乙醇、脱氢二氢-β-紫罗兰酮、(E,Z)-2,6-壬二烯醛、β-芳樟醇、癸醛和1,2,3-三甲氧基苯的OAV≥50,可以说明这些化合物对槟榔香六堡茶整体香气形成贡献度较大。通过比较GC-O-MS和OAV分析,2种分析方法筛选槟榔香六堡茶关键香气物质的结果基本一致,该研究为六堡茶陈化过程中“槟榔香”的形成提供理论依据以及对于定向加工“槟榔香”六堡茶具有指导意义。

关键词：六堡茶槟榔香关键香气物质气相色谱-嗅闻仪-质谱气味活力值

Threonine 32 （Thr32） of FoxO3 is critical for TGF-β-induced apoptosis via Bim in hepatocarcinoma cells

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Protein & Cell 2015年第2期6卷 127-138页

作者： Xiangxuan Zhao Yong Liu Lei Du leya He Biyun Ni Junbo Hu Dahai Zhu Quan Chen The Joint Laboratory of Apoptosis and Cancer Biology The State Key Laboratory of Biomembrane and Membrane Biotechnology Institute of Zoology Chinese Academy of Sciences Beijing 100101 China University of Chinese Academy of Sciences Beijing 100049 China Department of Radiology Shengjing Hospital of China Medical University Shenyang 110004 China Cancer Research Center Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430032 China Institute of Basic Medical Sciences of Chinese Academy of Medical Sciences and School of Basic Medicine of Peking Union Medical College Beijing 100005 China College of Life Science Nankai University Tianjin 300071 China

Transforming growth factor-β （TGF-β） exerts apoptotic effects on various types of malignant ceils, including liver cancer cells. However, the precise mechanisms by which TGF-β induces apoptosis remain poorly known. In the present study, we have showed that threonine 32 （Thr32） residue of FoxO3 is critical for TGF-β to induce apoptosis via Bim in hepatocarcinoma Hep3B cells. Our data demonstrated that TGF-βinduced FoxO3 activation through specific de-phosphorylation at Thr32. TGF-β-activated FoxO3 cooperated with Smad2/ 3 to mediate Bim up-regulation and apoptosis. FoxO3 （de）phosphorylation at Thr32 was regulated by casein kinase I-ε （CKI-E）. CKI inhibition by small molecule D4476 could abrogate TGF-β-induced FoxO/Smad acti- vation, reverse Bim up-regulation, and block the sequential apoptosis. More importantly, the deregulated levels of CKI-ε and p32FoxO3 were found in human malignant liver tissues. Taken together, our findings suggest that there might be a CKI-FoxO/Smad-Bim engine in which Thr32 of FoxO3 is pivotal for TGF-β- induced apoptosis, making it a potential therapeutic target for liver cancer treatment.

关键词： apoptosis TGF-β FoxO3 casein kinasel-ε hepatocarcinoma

CDK1-mediated the onset of apoptosis following ultraviolet radiation

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The Chinese-German Journal of Clinical Oncology 2009年第5期8卷 279-281页

作者： Xin Wei leya He Xiaolan Li Hui Xiao Deding Tao Junbo Hu Jianping Gong Cancer Research Institute/Department of General Surgery Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 China

Objective:To find out whether CDK1 could appear the important role in the cell apoptosis that induced by ultraviolet ***:We constructed two kinds of plasmids, one can expressed CDK1 but mutated the fifth amino acid(group A ) and the other can effectively silence the expression of CDK1(group B).When we transfected these plasmids into the 293 cells and at the same time following ultraviolet radiation, we detected the difference of two group cells' apoptosis ratio by subG1 peak assay and want to clarify the mechanism by Western blot ***:Two kinds of plasmids could effectively express in 293 *** apoptosis ratio of group A was higher than the group B(P < 0.01).And the apoptosis ratio of group B was lower than the group C(P < 0.01).Compared with group A and C, the expression of Bcl2 of group B was significantly ***:CDK1 may take a very important role in the programmed cell death.

关键词： CDK1 apoptosis ultraviolet radiation flow cytometry

Analysis of the effects of donor and recipient hepatitis C infection on kidney transplant outcomes in the United States

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World Journal of Transplantation 2023年第2期13卷 44-57页

作者： Qing Yuan Shanjuan Hong Gregory leya Eve Roth Georgios Tsoulfas WW Williams Joren C Madsen Nahel Elias Department of Urology Chinese PLA General HospitalBeijing 100853China Transplant Center and Center for Transplantation Sciences Massachusetts General HospitalBostonMA 02114United States Department of Surgery Aristototle University of ThessalonikiThessaloniki 54124Greece Department of Medicine Massachusetts General HospitalBostonMA 02114United States Division of Cardiac Surgery Massachusetts General HospitalBostonMA 02114United States Division of Transplant Surgery Massachusetts General HospitalBostonMA 02114United States

BACKGROUND As Hepatitis C virus infection(HCV+)rates in kidney donors and transplant recipients rise,direct-acting antivirals(DAA)may affect *** To analyze the effects of HCV+in donors,recipients,or both,on deceased-donor(DD)kidney transplantation(KT)outcomes,and the impact of DAAs on those *** The Organ Procurement and Transplantation Network data of adult first solitary DD-KT recipients 1994-2019 were allocated into four groups by donor and recipient HCV+*** performed patient survival(PS)and death-censored graft survival(DCGS)pairwise comparisons after propensity score matching to assess the effects of HCV+in donors and/or recipients,stratifying our study by DAA era to evaluate potential effect *** Pre-DAA,for HCV+recipients,receiving an HCV+kidney was associated with 1.28-fold higher mortality(HR 1.151.281.42)and 1.22-fold higher death-censored graft failure(HR 1.***.221.39)compared to receiving an HCV-kidney and the absolute risk difference was 3.3%(95%CI:1.8%-4.7%)for PS and 3.1%(95%CI:1.2%-5%)for DCGS at 3 *** HCV dual-infection(donor plus recipient)group had worse PS(0.56-fold)and DCGS(0.71-fold)than the *** HCV+derived worse post-transplant outcomes than recipient HCV+(PS 0.36-fold,DCGS 0.34-fold).In the DAA era,the risk associated with HCV+in donors and/or recipients was no longer statistically significant,except for impaired PS in the dual-infected vs dual-uninfected(0.43-fold).CONCLUSION Prior to DAA introduction,donor HCV+negatively influenced kidney transplant outcomes in all recipients,while recipient infection only relatively impaired outcomes for uninfected *** adverse effects disappeared with the introduction of DAA.

关键词： Hepatitis C virus Kidney transplantation Direct-acting antiviral therapy Propensity score matching