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一种基于奇异值分解的带噪语音识别方法

华南理工大学学报（自然科学版） 2001年第1期29卷 91-93页

作者：徐金甫韦岗梁树雄华南理工大学电子与信息学院广东广州510640 香港城市大学工程系

提出了一种抗噪声的语音识别方法 .用于训练和用于测试的语音信号在提取特征之前 ,均需经过相同的奇异值分解滤波 .本文还提出了一种滤波参数的选取方法 .实验证明 ,采用这种方法可以大幅度提高传统隐马尔可夫模型语音识别系统的抗噪声... 详细信息

提出了一种抗噪声的语音识别方法 .用于训练和用于测试的语音信号在提取特征之前 ,均需经过相同的奇异值分解滤波 .本文还提出了一种滤波参数的选取方法 .实验证明 ,采用这种方法可以大幅度提高传统隐马尔可夫模型语音识别系统的抗噪声性能 .

关键词：语音处理语音识别信号处理抗噪声性能奇异值分解滤波隐弥可夫模型噪声消减

Asymptotic false discovery control of the Benjamini-Hochberg procedure for pairwise comparisons

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Science China Mathematics 2025年第1期 223-252页

作者： Weidong Liu Dennis leung Qi-Man Shao School of Mathematical Sciences Shanghai Jiao Tong University School of Mathematics and Statistics University of Melbourne Department of Statistics and Data Science SICMSouthern University of Science and Technology

In a one-way analysis-of-variance(ANOVA) model,the number of pairwise comparisons can become large even with a moderate number of *** by this,we consider a regime with a growing number of groups and prove that,when testing pairwise comparisons,the Benjamini-Hochberg(BH) procedure can asymptotically control false discoveries,despite the fact that the involved t-statistics do not exhibit the wellknown positive dependence structure required for exact false discovery rate(FDR) *** Tukey's perspective that the difference between the means of any two groups cannot be exactly zero,our main result provides control over the directional false discovery rate and directional false discovery proportion.A key technical contribution of our work is demonstrating that the dependence among the t-statistics is sufficiently weak to establish the convergence result typically required for asymptotic FDR *** analysis does not rely on conventional assumptions such as normality,variance homogeneity,or a balanced design,thereby offering a theoretical foundation for applications in more general settings.

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Development of Integrative Medicine in Hong Kong,China

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Chinese Journal of Integrative Medicine 2017年第7期23卷 486-489页

作者： leung Ting hung Wendy Wong School of Chinese Medicine The Chinese University of Hong Kong Hong Kong SAR China Hong Kong Institute of Integrative Medicine The Chinese University of Hong KongHong Kong SAR China

Upon reflection on the experience of integration of Chinese medicine（CM）and Western medicine（integrative medicine）in the China's Mainland in recent decades,this paper aims to review the recent developments of CM a... 详细信息

关键词： integrative Mainland collaboration disciplines challenging curriculum university heritage medicines deviation

Stochastic seismic slope stability assessment using polynomial chaos expansions combined with relevance vector machine

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Geoscience Frontiers 2021年第1期12卷 405-414页

作者： Qiu-Jing Pan Yat-Fai leung shu-Chien Hsu School of Civil Engineering Central South UniversityNo.22Shaoshan South RoadChangsha410075China Department of Civil and Environmental Engineering The Hong Kong Polytechnic UniversityHung HomHong KongChina

This paper presents probabilistic assessment of seismically-induced slope displacements considering uncertainties of seismic ground motions and soil properties.A stochastic ground motion model representing both the temporal and spectral non-stationarity of earthquake shakings and a three-dimensional rotational failure mechanism are integrated to assess Newmark-type slope displacements.A new probabilistic approach that incorporates machine learning in metamodeling technique is proposed,by combining relevance vector machine with polynomial chaos expansions(RVM-PCE).Compared with other PCE methods,the proposed RVM-PCE is shown to be more effective in estimating failure *** sensitivity and relative influence of each random input parameter to the slope displacements are ***,the fragility curves for slope displacements are established for sitespecific soil conditions and earthquake hazard *** results indicate that the slope displacement is more sensitive to the intensities and strong shaking durations of seismic ground motions than the frequency contents,and a critical Arias intensity that leads to the maximum annual failure probabilities can be identified by the proposed approach.

关键词： Earthquake 3D slope stability Failure probability Seismic displacements Seismic hazard analysis

Pivotal role of cytosolic phospholipase PLA2G4A in the pathogenesis of FLT3-ITD-mutated acute myeloid leukemia

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Genes & Diseases 2023年第1期10卷 22-25页

作者： Wen-Jing Lai Fan Chen Lingling shu Xin-Ming Yang Jimin Yuan Jing-Bo Xu Anskar Yu-hung leung BaiLiang He Guangdong Provincial Key Laboratory of Biomedical Imaging Guangdong Provincial Engineering Research Center of Molecular ImagingThe Fifth Affiliated HospitalSun Yat-sen UniversityZhuhaiGuangdong 519000China Department of Hematologic Oncology State Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineSun Yat-sen University Cancer CenterGuangzhouGuangdong 510060China Department of Geriatric Medicine Shenzhen People’s Hospital(The Second Clinical Medical CollegeJinan UniversityThe First Affiliated HospitalSouthern University of Science and Technology)ShenzhenGuangdong 518020China Department of Hematology The Fifth Affiliated HospitalSun Yat-sen UniversityZhuhaiGuangdong 519000China Division of Haematology Department of MedicineLi Ka Shing Faculty of MedicineThe University of Hong KongPokfulamHong Kong 999077China

Internal tandem duplication of FMs-like tyrosine kinase 3(FLT3-ITD)is one of the most common genetic alterations in human acute myeloid leukemia(AML)and confers a poor prognosis for the disease.1 Though several FLT3 inhibitors have been approved in AML,their clinical benefits are still unsatisfactory due to primary refractory and drug ***,it may be crucial to develop novel therapeutics forFLT3-ITD+AML.

关键词： acute myeloid alterations

Polyethylene glycol fusion repair of severed sciatic nerves accelerates recovery of nociceptive sensory perceptions in male and female rats of different strains

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Neural Regeneration Research 2025年第9期20卷 2667-2681页

作者： Liwen Zhou Karthik Venkudusamy Emily A.Hibbard Yessenia Montoya Alexa Olivarez Cathy Z.Yang Adelaide leung Varun Gokhale Guhan Periyasamy Zeal Pathak Dale R.Sengelaub George D.Bittner Department of Neuroscience University of TexasAustinTXUSA Program in Neuroscience Indiana UniversityBloomingtonINUSA Department of Molecular Biosciences University of TexasAustinTXUSA

Successful polyethylene glycol fusion(PEG-fusion)of severed axons following peripheral nerve injuries for PEG-fused axons has been reported to:(1)rapidly restore electrophysiological continuity;(2)prevent distal Wallerian Degeneration and maintain their myelin sheaths;(3)promote primarily motor,voluntary behavioral recoveries as assessed by the Sciatic Functional Index;and,(4)rapidly produce correct and incorrect connections in many possible combinations that produce rapid and extensive recovery of functional peripheral nervous system/central nervous system connections and reflex(e.g.,toe twitch)or voluntary *** preceding companion paper describes sensory terminal field reo rganization following PEG-fusion repair of sciatic nerve transections or ablations;howeve r,sensory behavioral recovery has not been explicitly explored following PEG-fusion *** the current study,we confirmed the success of PEG-fusion surgeries according to criteria(1-3)above and more extensively investigated whether PEG-fusion enhanced mechanical nociceptive recovery following sciatic transection in male and female outbred Sprague-Dawley and inbred Lewis *** nociceptive responses were assessed by measuring withdrawal thresholds using von Frey filaments on the dorsal and midplantar regions of the *** von Frey filament tests were a more reliable method than plantar von Frey filament tests to assess mechanical nociceptive sensitivity following sciatic nerve *** withdrawal thresholds of the sciatic-mediated lateral dorsal region differed significantly across strain but not *** thresholds did not change significantly from baseline in chronic Unoperated and Sham-operated *** sciatic transection,all rats exhibited severe hyposensitivity to stimuli at the lateral dorsal region of the hindpaw ipsilateral to the ***,PEG-fused rats exhibited significantly earlier return to baseline withdrawal thresholds than Negative

关键词： autophagia axotomy collateral sprouting neuropathic pain peripheral nerve repair polyethylene glycol fusion(PEG-fusion) saphenous nerve sensory neurons sex and strain Wallerian degeneration

Message from Deputy Editor-in-Chief Gabriel M leung—International Trade and Global Health Protection

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China CDC weekly 2019年第4期1卷 45-46页

作者： Gabriel M leung China CDC Weekly Dean of Medicine The University of Hong KongHong Kong SARChina

It was external trade that first prompted the collection and reporting of surveillance data at the foreign ports from which the US imported *** established Bulletin of the Public Health—the first precursor to the US ... 详细信息

关键词： Trade prompt Health

Syntheses,structures,and reactivity of ruthenium(Ⅱ) hydride complexes containing Klui's oxygen tripodal ligand

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Science China Chemistry 2010年第10期53卷 2139-2143页

作者： NG Ho-Yuen LAI Chun-Sing WILLIAMS Ian D. leung Wa-hung Department of Chemistry The Hong Kong University of Science and Technology

Treatment of Ru(CO)(Cl)(H)(PPh3)3 with NaLOEt (LOEt-= [CpCo{P(O)(OEt)2}3]-) afforded the hydride complex (PPh3)(CO)-LOEtRu(H) (1), which has been characterized by X-ray crystallography. Similarly, the tricyclohexylphosphine analogue, (PCy3)(CO)LOEtRu(H) (2), was synthesized from Ru(CO)Cl(H)(PCy3)2 and NaLOEt. Treatment of complex 1 with R'SO2N3 afforded the (arylsulfonyl)amido complexes LOEtRu(CO)(PPh3)(NHSO2R) (R = 2,4,6-i-Pr3C6H2 (3), 4-t-BuC6H4 (4)). The crystal structure of complex 3 has been determined. The Ru-N distance and Ru-N-S angle in 3 are 2.076(3) and 126.14(16)°, respectively. Reactions of complex 1 with acids have been studied.

关键词： ruthenium oxygen tripodal ligand hydride complex (arylsulfonyl)amido complex

Chinese topical herbal medicine gives additive effect on pharmaceutical agent on fracture healing

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Journal of Traditional Chinese Medicine 2019年第6期39卷 853-860页

作者： Siu Wing Sum Shiu Hoi Ting shum Wai Ting Ko Chun Hay Lau Clara Bik San hung leung Kim leung Ping Chung Institute of Chinese Medicine The Chinese University of Hong KongShatinNew TerritoriesHong Kong China State Key Laboratory of Research on Bioactivities and Clinical Applications of Medicinal Plants The Chinese University of Hong KongShatinNew TerritoriesHong Kong China Department of Orthopaedics and Traumatology The Chinese University of Hong KongShatinNew TerritoriesHong Kong China

OBJECTIVE:To investigate the efficacy on the combination of oral strontium ranelate(Sr R)with a topical Chinese herbal paste on facilitation of fracture ***:An open fracture was created at the mid-shaft of the right tibia of rat.A herbal pastecalled CDR containing Honghua(Flos Carthami),Chuanxuduan(Radix Dipsaci Asperoidis)and Dahuang(Radix Et Rhizoma Rhei Palmati)was *** rats were treated with either CDR topically on the fracture site,or Sr R orally,or their *** turnover biochemical markers in serum were *** of the fracture was analyzed using micro-CT after 14 and 28 d,followed by histomorphometrical ***:Micro-computed tomography analysis revealed that the combined treatment of CDR with600 mg/g Sr R significantly increased the total callus density,mineralized callus volume fraction,mineralized callus mineral content and mineralized callus density of the callus after 28 d of *** result was consistent with the histomorphometrical analysis on the osteoid *** of biochemical markers showed that the combined treatments reduced the bone resorption that occurs temporarily after ***:This study demonstrated that the combined treatment of oral Sr R and topical CDR is effective to promote fracture healing by their additive effect on promoting bone formation and retarding bone resorption.

关键词： Fracture healing Osteogenesis Bone resorption Medicine,Chinese Traditional Integrative medicine Strontium ranelate