检索结果-南通市图书馆

Genetic dissection of ear-related traits using immortalized F2 population in maize

Journal of Integrative Agriculture 2022年第9期21卷 2492-2507页

作者： GAO Ri-xin HU Ming-jian ZHAO Hai-ming lai jin-sheng SONG Wei-bin State Key Laboratory of Plant Physiology and Biochemistry&National Maize Improvement Center Department of Plant Genetics and BreedingChina Agricultural UniversityBeijing 100193P.R.China Center for Crop Functional Genomics and Molecular Breeding China Agricultural UniversityBeijing 100193P.R.China

Ear-related traits are often selection targets for maize improvement. This study used an immortalized F(IF) population to elucidate the genetic basis of ear-related traits. Twelve ear-related traits(namely, row number(RN), kernel number per row(KNPR), ear length(EL), ear diameter(ED), ten-kernel thickness(TKT), ear weight(EW), cob diameter(CD),kernel length(KL), kernel width(KW), grain weight per ear(GW), 100-kernel weight(HKW), and grain yield per plot(GY)),were collected from the IFpopulation. The ear-related traits were comprised of 265 crosses derived from 516 individuals of the recombinant inbred lines(RILs) under two separated environments in 2017 and 2018, respectively. Quantitative trait loci(QTLs) analyses identified 165 ear traits related QTLs, which explained phenotypic variation ranging from 0.1 to 12.66%. Among the 165 QTLs, 19 underlying nine ear-related traits(CD, ED, GY, RN, TKT, HKW, KL, GW, and KNPR)were identified across multiple environments and recognized as reliable QTLs. Furthermore, 44.85% of the total QTLs showed an overdominance effect, and 12.72% showed a dominance effect. Additionally, we found 35 genomic regions exhibiting pleiotropic effects across the whole maize genome, and 17 heterotic loci(HLs) for RN, EL, ED and EW were identified. The results provide insights into genetic components of ear-related traits and enhance the understanding of the genetic basis of heterosis in maize.

关键词： maize(Zea mays L.) QTL mapping genotyping by sequencing immortalized F2 population ear-related traits

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

CYP2J2-derived EETs attenuated Angiotensin Ⅱ-induced adventitial remodeling via reduced inflammatory response

引用

中国病理生理杂志 2016年第8期32卷 1507-1508页

作者： ZHOU Chi HUANG jin CHEN Jun-xiong lai jin-sheng ZHU Fa-sheng XU Xi-zhen WANG Dao-wen Department of Internal Medicine and The Institute of Hypertension Tongji HospitalTongji Medical College of Huazhong University of Science and Technology

BACKGROUND: Cytochrome P450( CYP) epoxygenases metabolize arachidonic acids( AA) to form epoxyeicosatrienoic acids (EETs),which exert beneficial roles in the treatment of cardiovascular diseases,but little is known about its role on adventitial remodeling. METHODS: We used C57 BL /6J mice in vivo and primary rat adventitial fibroblasts( AFs) in vitro treated with angiotensin II(Ang II) to investigate the effects of CYP2J2 gene delivery and exogenous EETs administration on adventitial remodeling. RESULTS:CYP / s EH system was found to exist in human adventitia,and involved in adventitial remodeling process. Exogenous EETs administration significantly inhibited Ang II-induced AFs activation,characterized by differentiation,proliferation,migration,and collagen synthesis. These protective effects were partially reversed by PPARγ antagonist GW9662 pretreatment or SOCS3 si RNA transfection. EETs suppressed Ang II-induced IκBα phosphorylation,subsequent NF-κB nuclear translocation via PPARγ dependent signaling pathway in AFs. Additionally,EETs reduced Ang II-induced JAK2,STAT3 phosphorylation and subsequent phosphor-STAT3 nuclear translocation,which were mediated by SOCS3 induction but independent of PPARγ activation. Furthermore,r AAV-CYP2J2 gene delivery reduced vessel wall thickening,AFs differentiation,proliferation and collagen deposition in aortic adventitia induced by Ang II infusion,which were mediated by NF-κB and SOCS3 / JAK / STAT signaling pathways in blood pressure-dependent and-independent manners,respectively. CONCLUSION: We concluded that CYP2J2 overexpression attenuated Ang II-induced adventitial remodeling via PPARγ-dependent NF-κB and PPARγ-independent SOCS3 / JAK / STAT inflammatory signaling pathways.

关键词： CYP2J2-derived EETs attenuated Angiotensin induced adventitial remodeling via reduced inflammatory response PPAR SOCS

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

花生四烯酸的细胞色素P450酶代谢途径产物EETs和20-HETE在血管功能调控中的作用

引用

生理学报 2021年第4期73卷 631-645页

作者：赖金胜陈琛华中科技大学同济医学院附属同济医院心血管内科武汉430030 湖北省心血管病遗传与分子机制重点实验室武汉430030

花生四烯酸(arachidonic acids,AA)广泛存在于生物体内,并可通过多种途径代谢成为具有强大生物学功能的脂质小分子。其中,经细胞色素P450酶代谢途径产生的环氧二十碳三烯酸(epoxyeicosatrienoic acids,EETs)及20-羟基二十碳四烯酸(20-hy... 详细信息

花生四烯酸(arachidonic acids,AA)广泛存在于生物体内,并可通过多种途径代谢成为具有强大生物学功能的脂质小分子。其中,经细胞色素P450酶代谢途径产生的环氧二十碳三烯酸(epoxyeicosatrienoic acids,EETs)及20-羟基二十碳四烯酸(20-hydroxyeicosatetraenoic acid,20-HETE)的作用备受关注,尤其是在血管稳态中的作用。血管功能调控是维持血管稳态的基础,主要通过对血管的结构和(或)生物学活性的影响而实现。近30年来,EETs及20-HETE在血管功能调控中的作用及机制被广泛研究。本文分别就EETs和20-HETE在血管新生和血管炎症反应等方面的研究进展逐一进行综述。总的来说,在生物学活性方面,EETs主要体现为舒张血管和抑制血管炎症,而20-HETE则可以促进血管收缩和血管炎症。两者在血管新生方面的作用类似,都可以促进血管新生。另外,本文还对EETs和20-HETE在常见的血管性疾病(如高血压和心肌缺血)中的作用进行了探讨,对其中的作用机制进行了分析和总结,并对基于EETs和20-HETE的血管性疾病靶向治疗提出了展望。

关键词：花生四烯酸细胞色素P450酶 EETs 20-HETE 血管功能血管性疾病

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effects of 50-Hz magnetic field on the cardiovascular system in rats

引用

中国病理生理杂志 2016年第8期32卷 1498-1499页

作者： lai jin-sheng WAN Bao-quan LIU Xing-fa ZHANG Ye-mao RUAN Guo-ran HE Meng-ying CHEN Chen WANG Dao-wen Division of Cardiology Department of Internal MedicineTongji HospitalTongji Medical CollegeHuazhong University of Science and Technology State Key Laboratory of Power Grid Environmental Protection China Electric Power Research Institute

AIM: The 50-Hz magnetic field( MF) is a potential health-risk factor. Its effects on the cardiovascular system have not been fully investigated. This study was conducted to explore the effects of long-term exposure to 50-Hz MF on the cardiovascular ***: In the study,an exposure system was constructed and the distribution of 50-Hz MF was detected. Sixty-four SpragueDawley( SD) rats were exposed to 50-Hz MF at 100 μT for 24 weeks,20 hours per day,while another 64 rats were sham *** the exposure,blood pressure was measured every 4 weeks,and 24 weeks later,echocardiography,cardiac catheterisation and electrocardiography were performed. Moreover,heart and body weight were recorded,while haematoxylin-eosin staining and real-time PCR were conducted. RESULTS: The results showed that compared with the sham group,exposure to 50-Hz MF did not exert any effect on blood pressure,pulse rate,heart rate and cardiac rhythm. Further,echocardiography and cardiac catheterisation showed that there were no significant differences in the cardiac morphology and haemodynamics. In addition,histopathological examination showed that 50-Hz MF exposure had no effect on the structure of hearts. Finally,the expression of the cardiac hypertrophic relative genes did not show any significant differences between 50-Hz MF exposure group and the sham group. CONCLUSION: Taken together,in SD rats,exposure to 50-Hz /100-μT MF for 24 weeks did not show any obvious effects on the cardiovascular system.

关键词： Effects of 50-Hz magnetic field on the cardiovascular system in rats

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Extraordinary Vessels Needling for Vascular Dementia

引用

Journal of Acupuncture and Tuina Science 2003年第1期1卷 17-19页

作者： YU jin lai Xin-sheng HUANG Qiu-tang XIAO Yuan-chun Acupuncture and Tuina School Guangzhou University of TCM Guangdong 510405 China Acupuncture and Tuina School Guangzhou University of TCM Guangdong 510405 China The First Hospital Affiliated to Guangzhou University of TCM Guangdong 510405 China

Purpose To observe the clinical efficacy of extraordinary vessels needling in treating vascular *** 39 cases vascular dementia were treated by acupoints selected from the eight extraordinary meridians and the time needling techniques such as eight methods of spiritual turtle, in accordance with time period and pattern *** 2 cases were cured, 30 cases improved and 7 cases failed; the total effective rate was 82.1%.Conclusion Extraordinary vessels needling has positive effects in treating vascular dementia. Key Words Dementia, Vascular - Acupuncture Therapy - Chronotherapeutics - Eight extra-meridians Foundation Item: Natural Science Fund of Guangdong Province (960548)Author: YU jin (1972-), female, lecture and attending physicianTranslator: XIAO Yuan-chun

关键词： Dementia, Vascular Acupuncture Therapy Chronotherapeutics Eight extra-meridians

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

牵引变电所备自投试验仪的研制

引用

铁道机车车辆 2010年第6期30卷 103-106页

作者：靳来生郑州铁路局郑州供电段河南郑州450061

阐述了在电气化铁路繁忙干线进行牵引变电所备自投试验的必要性和困难性,通过分析牵引变电所综合自动化系统的备自投实现原理,介绍了一种近年来研发的无需利用天窗点开展牵引变电所备自投试验的仪器。

关键词：牵引变电所备自投混合仿真系统综合自动化

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

日本津田故障点标定装置数字接口的研制

引用

铁道机车车辆 2010年第1期30卷 94-96页

作者：靳来生郑州铁路局郑州供电段河南郑州450061

介绍了在既有线牵引变电所综合自动化改造过程中,针对日本津田故障点标定装置接入国产综合自动化系统时所需要的数字接口装置的研制过程、工作原理及性能特点。

关键词：综合自动化故障点标定数字接口智能判断

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

我国农村扶贫的制度性陷阱与制度创新

引用

农业现代化研究 2009年第2期30卷 184-188页

作者：徐孝勇赖景生寸家菊重庆师范大学经济与管理学院重庆400047 重庆工商大学经济贸易学院重庆400067 重庆大学贸易与行政学院重庆400044

本文在从博弈理论和农民的权利贫困角度,分析我国农村扶贫的制度性陷阱生成机理的基础上,提出了开展农村扶贫制度创新和构建"市场+政府+民主协商"准市场化农村扶贫资源配置机制等,打破我国农村扶贫的制度性陷阱和推进农村扶贫事业发展... 详细信息

本文在从博弈理论和农民的权利贫困角度,分析我国农村扶贫的制度性陷阱生成机理的基础上,提出了开展农村扶贫制度创新和构建"市场+政府+民主协商"准市场化农村扶贫资源配置机制等,打破我国农村扶贫的制度性陷阱和推进农村扶贫事业发展的对策及措施。

关键词：农村扶贫制度性陷阱权利贫困制度创新

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

节水灌溉技术措施分析

引用

南水北调与水利科技 2009年第A1期7卷 119-120,143页

作者：来金生新疆博乐农五师全新勘测设计有限公司新疆博乐833400

节水灌溉技术内容十分广泛，包括技术、农业、管理、政策法规等多方面的措施，如各种水源开发与优化利用措施、农业耕作栽培节水技术措施以及节水灌溉措施等。

关键词：节水灌溉技术措施分析

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

高速电梯液压张紧装置的设计及研究

引用

液压与气动 2017年第4期41卷 77-81页

作者：冯斌林建杰金来生西子电梯集团浙江杭州310016

针对高速电梯的补偿钢丝绳在电梯正常工作时存在一定的抖动和在紧急工况能够产生巨大的冲击力等特点,设计了一套液压系统控制的补偿钢丝绳张紧装置。利用AMESim仿真分析了两种工况下的系统响应,结果表明采用该液压系统控制的张紧装置,... 详细信息

针对高速电梯的补偿钢丝绳在电梯正常工作时存在一定的抖动和在紧急工况能够产生巨大的冲击力等特点,设计了一套液压系统控制的补偿钢丝绳张紧装置。利用AMESim仿真分析了两种工况下的系统响应,结果表明采用该液压系统控制的张紧装置,在发生紧急工况时可以快速输出足够的力来阻止钢丝绳的上跳,以保证电梯的安全;在正常运行时液压系统的阻尼作用也有效降低了钢丝绳的晃动,提高了电梯的平稳性。

关键词：高速电梯张紧装置防跳液压系统 AMESim仿真

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：