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Effects of 50-Hz magnetic field on the cardiovascular system in rats

Effects of 50-Hz magnetic field on the cardiovascular system in rats

作     者:LAI Jin-sheng WAN Bao-quan LIU Xing-fa ZHANG Ye-mao RUAN Guo-ran HE Meng-ying CHEN Chen WANG Dao-wen 

作者机构:Division of CardiologyDepartment of Internal MedicineTongji HospitalTongji Medical CollegeHuazhong University of Science and Technology State Key Laboratory of Power Grid Environmental ProtectionChina Electric Power Research Institute 

出 版 物:《中国病理生理杂志》 (Chinese Journal of Pathophysiology)

年 卷 期:2016年第32卷第8期

页      面:1498-1499页

核心收录:

学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基  金:Supported by the Science and Technology Project of the State Grid Corporation of China(No.GY71-13-057) 

主  题:Effects of 50 Hz magnetic field on the cardiovascular system in rats 

摘      要:AIM: The 50-Hz magnetic field( MF) is a potential health-risk factor. Its effects on the cardiovascular system have not been fully investigated. This study was conducted to explore the effects of long-term exposure to 50-Hz MF on the cardiovascular ***: In the study,an exposure system was constructed and the distribution of 50-Hz MF was detected. Sixty-four SpragueDawley( SD) rats were exposed to 50-Hz MF at 100 μT for 24 weeks,20 hours per day,while another 64 rats were sham *** the exposure,blood pressure was measured every 4 weeks,and 24 weeks later,echocardiography,cardiac catheterisation and electrocardiography were performed. Moreover,heart and body weight were recorded,while haematoxylin-eosin staining and real-time PCR were conducted. RESULTS: The results showed that compared with the sham group,exposure to 50-Hz MF did not exert any effect on blood pressure,pulse rate,heart rate and cardiac rhythm. Further,echocardiography and cardiac catheterisation showed that there were no significant differences in the cardiac morphology and haemodynamics. In addition,histopathological examination showed that 50-Hz MF exposure had no effect on the structure of hearts. Finally,the expression of the cardiac hypertrophic relative genes did not show any significant differences between 50-Hz MF exposure group and the sham group. CONCLUSION: Taken together,in SD rats,exposure to 50-Hz /100-μT MF for 24 weeks did not show any obvious effects on the cardiovascular system.

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