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Mechanism of subsidence-buckling and instability of slopes in thick-layered rigid rock under mining

Journal of Mountain Science 2023年第8期20卷 2370-2387页

作者： DENG Jie ZHAO Jian-jun lai qi-yi LI Ai-nong XIE Ming-li LI qing-miao ZHAO Xiao State Key Laboratory of Geohazard Prevention and Geoenvironment Protection Chengdu University of TechnologyChengdu 610059China POWERCHINA Chengdu Engineering Corporation Limited Chengdu 610072China

The deformation and failure of mining slopes in layered rocks predominantly result from shear ***,the instability process of the Pusa rock avalanche in Guizhou,China,revealed a unique damage phenomenon:prominent breaking and toppling of rock blocks occurred in the central section of the mountain,with a lack of commonly observed shear landslide *** paper aims to investigate the underlying reasons behind this distinctive damage *** study employs various methods including geological survey,UAV aerial survey,physical simulation,and discrete element numerical *** findings indicate that the geological conditions,characterized by a hard upper layer and a soft lower layer along with underground mining activities,play a significant role in triggering the ***,the presence of a columnar structured rock mass emerges as the primary factor influencing the instability of the Pusa rock *** elucidate the mining failure mechanism of the rock mass with vertical joints,we propose a"subsidence-buckling"failure *** the subsidence and collapse of the roof rock mass in the goaf,the columnar rock mass in the upper and middle portions of the slope undergoes deflection and deformation,forming a three-hinged arch *** structural configuration converts the pressure exerted by the overlying rock mass into both vertical pressure and lateral *** the influence of external loads,the slope experiences buckling failure,ultimately leading to instability upon *** shedding light on these findings,this study contributes to a better understanding of the spatiotemporal evolution of mining slope fractures and their impact on slope stability.

关键词： Mining landslide Failure mechanism Block structure Failure characteristics Soft-hard interbedding

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Deformation and failure of a high-steep slope induced by multi-layer coal mining

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Journal of Mountain Science 2020年第12期17卷 2942-2960页

作者： YU Jian-le ZHAO Jian-jun YAN Hao-yuan lai qi-yi HUANG Run-qiu LIU Xiu-wei LI Yang-chun State Key Laboratory of Geohazard Prevention and Geoenvironment Protection Chengdu University of TechnologyChengdu 610059China Guizhou Transportation Planning Survey&Design Academy Co. ltd.Guiyang 550081China Guizhou Geological Environment Monitoring Institute Guiyang 550001China

During underground mining,accurate revelation on the deformation and failure mechanisms of a high-steep slope under multi-layer mining conditions facilitates the prevention and control of geological disasters in *** simulation based on discrete element theory can be used to explore the characteristics and mechanism of action of deformation and failure of a slope under complex geological and multi-layer mining *** utilising PFC2 D(particle flow code) software,the deformation and failure characteristics of a high-steep slope in Faer Coal Mine in Guizhou Province,China were ***,the mechanism of influence of different numbers of mining layers on the deformation and failure of the high and steep slope was *** result showed that after the goaf passed by the slope toe,multi-layer mining aggravated the subsidence and deformation of the slope toe:the slope toppled forward as it *** toppling of the slope changed the slope structures:the strata in the front of the slope were transformed from anti-dip to down-dip *** by collapsedtoppled rock mass,the slope toe and the rock mass located in the lower part of the slope toe generally exhibited a locking effect on the ***-layer mining degraded the overall stability of the slope,in that the total displacement of the slope was much greater than the total mining thickness of the coal *** on the aforementioned research,ideas for preventing and controlling geological disasters during mining operations under a high-steep slope were proposed.

关键词： High steep slope Discrete element method Multilayer coal mining Mountain mine geological hazard Subsidence toppling deformation Mining schemes optimization

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Electrocatalytic cleavage of a lignin β-O-4 model compound and coupling with nitrogen-containing aromatics using Prussian blue analogue-derived nickel–cobalt spinel

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Journal of Energy Chemistry 2025年第1期100卷 628-636页

作者： yi qi Xueying Chen Bowen Liu Xuliang Lin Xueqing qiu Yanlin qin Guangdong Provincial Key Laboratory of Plant Resources Biorefinery School of Chemical Engineering and Light Industry Guangdong University of Technology Guangdong Provincial Laboratory of Chemistry and Fine Chemical Engineering Jieyang Center Guangdong Basic Research Center of Excellence for Ecological Security and Green Development Guangdong University of Technology

Electrochemical conversion of lignin for the production of high-value heterocyclic aromatic compounds has great *** demonstrate the targeted synthesis and cation modulation of NiCo2O4spinel nanoboxes,synthesized via cation exchange and calcination *** catalysts exhibit excellent efficacy in the electrocatalytic conversion of lignin model compounds,specifically 2-phenoxy-1-phenylethanol,into nitrogen-containing aromatics,achieving high conversion rates and *** catalysts were synthesized via a cation exchange and calcination oxidation process,using Prussian blue nanocubes as *** porous architecture and polymetallic composition of the NiCo2O4spinel demonstrated superior performance in electrocatalytic oxidative coupling,achieving a 99.2 wt%conversion rate of the 2-phenoxy-1-phenylethanol with selectivities of 37.5 wt%for quinoline derivatives and 31.5 wt%for *** innovations include the development of a sustainable one-pot synthesis method for quinoline derivatives,the elucidation of a multistage reaction pathway involving CAO bond cleavage,hydroxyaldol condensation,and CAN bond formation,and a deeper mechanistic understanding derived from DFT *** work establishes a new strategy for lignin valorization,offering a sustainable route to produce high-value nitrogen-containing aromatics from renewable biomass under mild conditions,without the need for additional reagents.

关键词： Spinel Biomass valorization Electrocatalysis Lignin oxidation Coupling

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Meningeal lymphatic vessel crosstalk with central nervous system immune cells in aging and neurodegenerative diseases

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Neural Regeneration Research 2025年第3期20卷 763-778页

作者： Minghuang Gao Xinyue Wang Shijie Su Weicheng Feng Yaona lai Kongli Huang Dandan Cao qi Wang Science and Technology Innovation Center Guangzhou University of Chinese MedicineGuangzhouGuangdong ProvinceChina Institute of Clinical Pharmacology Guangzhou University of Chinese MedicineGuangzhouGuangdong ProvinceChina The Sixth Affiliated Hospital Sun Yat-sen UniversityGuangzhouGuangdong ProvinceChina

Meningeal lymphatic vessels form a relationship between the nervous system and periphery, which is relevant in both health and disease. Meningeal lymphatic vessels not only play a key role in the drainage of brain metabolites but also contribute to antigen delivery and immune cell activation. The advent of novel genomic technologies has enabled rapid progress in the characterization of myeloid and lymphoid cells and their interactions with meningeal lymphatic vessels within the central nervous system. In this review, we provide an overview of the multifaceted roles of meningeal lymphatic vessels within the context of the central nervous system immune network, highlighting recent discoveries on the immunological niche provided by meningeal lymphatic vessels. Furthermore, we delve into the mechanisms of crosstalk between meningeal lymphatic vessels and immune cells in the central nervous system under both homeostatic conditions and neurodegenerative diseases, discussing how these interactions shape the pathological outcomes. Regulation of meningeal lymphatic vessel function and structure can influence lymphatic drainage, cerebrospinal fluid-borne immune modulators, and immune cell populations in aging and neurodegenerative disorders, thereby playing a key role in shaping meningeal and brain parenchyma immunity.

关键词： central nervous system meningeal lymphatic vessels immunity myeloid cells lymphatic cells neurodegenerative disease

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恒轴压卸围压条件下粉砂岩应力应变特征与能量演化

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科学技术与工程 2023年第22期23卷 9624-9629页

作者：余建乐巫恩歌邓杰赖琪毅中国铁道科学研究院集团有限公司北京100081 国铁川藏科创中心(成都)有限公司成都610213 成都理工大学(地质灾害防治与地质环境保护国家重点实验室) 成都610059

为了获得高陡山区地下工程顶部粉砂岩在开挖后的应力应变和能量演化特征,开展了不同围压下粉砂岩恒轴压卸围压三轴试验,分析其应力应变、应变能转化以及能量耗散特征。结果表明,恒轴压卸围压条件下,围压越高,试样围压卸载率越低,且试样... 详细信息

为了获得高陡山区地下工程顶部粉砂岩在开挖后的应力应变和能量演化特征,开展了不同围压下粉砂岩恒轴压卸围压三轴试验,分析其应力应变、应变能转化以及能量耗散特征。结果表明,恒轴压卸围压条件下,围压越高,试样围压卸载率越低,且试样破坏越快、变形越大。不同围压下能量转化特征曲线趋势基本一致,与应力应变曲线有较好的相关性。围压恒定轴压升高阶段,除围压产生的应变能密度基本恒定外,其他能量演化曲线具有呈指数升高的特征;主要表现为原生孔隙压密,能量转化率较低。轴压恒定围压卸载至试样破坏阶段,轴向应力与能量曲线两者突变点基本对应;产生较大程度宏观破裂,能量转化率较高。试样破坏后围压恒定和继续施加轴向应变阶段,低围压能量释放更强,试样破坏更为碎裂。能量耗散具有总体上先升高后降低再陡增的特征,围压越低,试样破坏时应变越小、能量耗散比越大,试样破坏更加碎裂;围压越高,对试样能量耗散抑制作用越强,有利于弹性应变聚集,更容易产生岩爆现象。

关键词：粉砂岩应力路径应力应变特征能量演化特征碎裂差异

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降雨条件下不良填筑路基破坏过程物理模拟

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科学技术与工程 2019年第32期19卷 75-83页

作者：陈雨志赵建军余建乐李涛赖琪毅成都理工大学地质灾害防治与地质环境保护国家重点实验室成都610059 上海市政工程设计研究总院(集团)有限公司上海200092

为研究不良填筑路基在降雨条件下变形破坏机制,采用相似材料和物理模拟实验方法再现填方路基变形破坏全过程,揭示降雨和软弱夹层与不良填筑路基变形破坏的内在联系。研究表明,雨水和坡后汇聚水流大量下渗,路基自重增加,下滑推力增大,坡... 详细信息

为研究不良填筑路基在降雨条件下变形破坏机制,采用相似材料和物理模拟实验方法再现填方路基变形破坏全过程,揭示降雨和软弱夹层与不良填筑路基变形破坏的内在联系。研究表明,雨水和坡后汇聚水流大量下渗,路基自重增加,下滑推力增大,坡体应力条件发生显著改变。软弱夹层相对隔水,下渗雨水在软弱夹层上运移受阻,夹层浸水软化,于坡体稳定性产生不利影响。路基内部碎屑颗粒含量大,进而堵塞地下水消散通道,孔隙水压力持续增加,加剧坡体变形,最终导致路基失稳。该路基破坏过程可分为水流下渗、坡体应力调整、后缘拉裂缝形成、裂缝贯通-整体破坏四个阶段。

关键词：降雨不良填筑路基破坏过程物理模拟

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中国球针壳属分类的研究——Ⅱ.短附属丝子囊壳类型

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微生物学报 1979年第1期 11-23页

作者：余永年赖奕琪中国科学院微生物研究所

本文报道、描述了我国具短附属丝的球针壳属白粉菌15个种,其中6个新种和2个改级新组合。具短附属丝的球针壳类,其附属丝长度一般为子囊壳直径的0.5-1.5倍。新种为:①油桐球针壳Phyllactinia aleuritidis Yu et lai ***.,②桤木球针壳***... 详细信息

本文报道、描述了我国具短附属丝的球针壳属白粉菌15个种,其中6个新种和2个改级新组合。具短附属丝的球针壳类,其附属丝长度一般为子囊壳直径的0.5-1.5倍。新种为:①油桐球针壳Phyllactinia aleuritidis Yu et lai ***.,②桤木球针壳*** Yu etHan ***.,③蛇葡萄球针壳*** Yu et lai ***.,④木兰球针壳*** Yu et lai ***.,⑤泡桐球针壳*** Yu ***.及⑥中国球针壳*** Yu sp nov.。新组合为:臭椿球针壳Phyllactinia ailanthi（*** Bunk.）Yu ***.和杨球针壳***（Jacz.）Yu ***.还讨论了上述15个种与它们邻近种或相似种之间的区别。模式标本存中国科学院真菌标本室。

关键词：附属丝基部针形附属菌丝子囊壳球针壳属白粉菌科中华人民共和国

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中国叉丝壳属分类研究——Ⅴ.忍冬科上的新种和已知种

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真菌学报 1983年第2期 89-95页

作者：余永年赖奕琪中国科学院微生物研究所中国科学院微生物研究所北京北京、四川成都市工业发酵研究所

本文报道寄生于我国忍冬科植物上的叉丝壳属白粉菌5个种:双盾叉丝壳Microsphacra dipeltae Yu et lai sp. nov., 二郎山叉丝壳M. erlangshanensis Yu sp. nov.,忍冬叉丝壳M. lonicerae(DC.)Winter,万布叉丝壳M. van-brunctiana Gerard和荚蒾叉丝壳***(Duby)Blumer,前二者为新种;对新种作了汉文和拉丁文描述,并附有形态图。每一个种都列有寄主种类和国内外分布,并讨论了它们与邻近种之间的区别。

关键词：忍冬科叉丝壳属双盾叉丝壳二郎山叉丝壳忍冬叉丝壳万布叉丝壳荚蒾叉丝壳

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机器视觉系统中的光源控制器的设计与研究

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电脑知识与技术（过刊） 2015年第5X期21卷 195-196页

作者：赖伊琦刘益民陈锦儒韶关学院物理与机电工程学院广东韶关512005

该文提出了一种基于PID算法控制的LED光源控制器,叙述了光源控制器的总体设计方案、其主要的硬件电路设计、软件系统流程图以及PID算法的调试方式。该设计主要实现了人机界面的多页面切换功能、PID算法的控制、AD采集等程序设计及其对... 详细信息

该文提出了一种基于PID算法控制的LED光源控制器,叙述了光源控制器的总体设计方案、其主要的硬件电路设计、软件系统流程图以及PID算法的调试方式。该设计主要实现了人机界面的多页面切换功能、PID算法的控制、AD采集等程序设计及其对应的硬件电路的搭建,实现手动调节与自动调节一体化的光源控制器系统。

关键词： PID算法调试 AD采集光源控制器

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Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke

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Neural Regeneration Research 2025年第3期20卷 845-857页

作者： Lin-Yan Huang yi-De Zhang Jie Chen Hai-Di Fan Wan Wang Bin Wang Ju-Yun Ma Peng-Peng Li Hai-Wei Pu Xin-yian Guo Jian-Gang Shen Su-Hua qi School of Medical Technology Xuzhou Key Laboratory of Laboratory DiagnosticsXuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Pharmacy Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina Department of Laboratory Medicine Branch Hospital of Huai’an First People’s HospitalHuai’anJiangsu ProvinceChina Department of Laboratory Medicine the Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Chinese Medicine The University of Hong KongHong Kong Special Administrative RegionChina

It has been shown clinically that continuous removal of ischemia/reperfusion-induced reactive oxygen species is not conducive to the recovery of late ***,previous studies have shown that excessive increases in hypochlorous acid after stroke can cause severe damage to brain *** previous studies have found that a small amount of hypochlorous acid still exists in the later stage of stroke,but its specific role and mechanism are currently *** simulate stroke in vivo,a middle cerebral artery occlusion rat model was established,with an oxygen-glucose deprivation/reoxygenation model established in vitro to mimic *** found that in the early stage(within 24 hours)of ischemic stroke,neutrophils produced a large amount of hypochlorous acid,while in the recovery phase(10 days after stroke),microglia were activated and produced a small amount of hypochlorous ***,in acute stroke in rats,hypochlorous acid production was prevented using a hypochlorous acid scavenger,taurine,or myeloperoxidase inhibitor,4-aminobenzoic acid *** results showed that high levels of hypochlorous acid(200μM)induced neuronal apoptosis after oxygen/glucose deprivation/***,in the recovery phase of the middle cerebral artery occlusion model,a moderate level of hypochlorous acid promoted the proliferation and differentiation of neural stem cells into neurons and *** suggests that hypochlorous acid plays different roles at different phases of cerebral ischemia/reperfusion *** levels of hypochlorous acid(5 and 100μM)promoted nuclear translocation ofβ-*** transfection of single-site mutation plasmids,we found that hypochlorous acid induced chlorination of theβ-catenin tyrosine 30 residue,which promoted nuclear ***,our study indicates that maintaining low levels of hypochlorous acid plays a key role in the recovery of neurological function.

关键词： cell differentiation cerebral ischemia/reperfusion injury chlorination hypochlorous acid microglia neural stem cell neurogenesis nuclear translocation stroke β-catenin

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