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Infectious disease Modelling 2024年第1期9卷 234-244页

作者： Ashley n.Micuda Mark R.Anderson Irina Babayan Erin Bolger logan cantin Gillian Groth Ry Pressman-cyna charlotte z.Reed noah j.Rowe Mehdi Shafiee Benjamin Tam Marie c.Vidal Tianai ye Ryan d.Martin department of Physics Engineering Physics&AstronomyQueen's UniversityKingstonONCanada department of Medical Biophysics Western UniversityLondonONCanada department of Mathematics and Statistics Queen's UniversityKingstonONCanada department of Biology Queen's UniversityKingstonONCanada department of Electrical and computer Engineering Nazarbayev UniversityNur-SultanKazakhstan Energetic cosmos laboratory Nazarbayev UniversityNur-SultanKazakhstan School of computing Queen's UniversityKingstonONCanada department of Biomedical and Molecular Sciences Queen's UniversityKingstonONCanada department of Physics University of OxfordOxfordUnited Kingdom department of Physics Stanford UniversityStanfordCAUnited States

This work introduces the Queen's University Agent-Based Outbreak Outcome Model(QUABOOM).This tool is an agent-based Monte carlo simulation for modelling epidemics and informing public health *** illustrate the use of the model by examining capacity restrictions during a *** find that public health measures should focus on the few locations where many people interact,such as grocery stores,rather than the many locations where few people interact,such as small *** also discuss a case where the results of the simulation can be scaled to larger population sizes,thereby improving computational efficiency.

关键词： Monte-carlo Agent-based epidemic modelling cOVId-19 Small business capacity restrictions Public health Basic reproductive number

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人类排放情景的设计与全球变暖预估

气候变化研究进展 2024年第2期20卷 261-264页

作者：赵宗慈罗勇黄建斌清华大学地球系统科学系北京100084 中国气象局国家气候中心北京100081 中国科学院大学资源环境学院北京100049

1气候变化的原因全球气候变化除地球系统内部变率外,自然强迫和人为强迫是重要的外部驱动力。其中自然强迫包括太阳活动和火山活动。人为强迫即人类活动,包括大量化石燃料燃烧排放温室气体、土地利用,以及气溶胶与污染排放等,其强度取... 详细信息

1气候变化的原因全球气候变化除地球系统内部变率外,自然强迫和人为强迫是重要的外部驱动力。其中自然强迫包括太阳活动和火山活动。人为强迫即人类活动,包括大量化石燃料燃烧排放温室气体、土地利用,以及气溶胶与污染排放等,其强度取决于人口发展与变化、社会经济发展、技术变化及其内部的协调性等。本文重点给出人类强迫的影响。IPcc第六次评估报告明确表明,近百年特别是近几十年来观测到的全球变暖归因为人类活动的影响。

关键词：太阳活动火山活动排放情景全球变暖社会经济发展全球气候变化人类强迫变率

Previously undiagnosed Morgagni hernia with bowel perforation detected during repeat screening colonoscopy: A case report

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world journal of clinical cases 2024年第14期12卷 2389-2395页

作者： Said Al Alawi Alan n Barkun Sara najmeh division of Gastroenterology McGill UniversityMontrealQC H4A 3J1Canada division of Thoracic surgery McGill UniversityMontrealQC H4A 3J1Canada

BAcKGROUnd Morgagni hernia(Mh)is a form of congenital diaphragmatic hernia(cdh)characterized by an incomplete formation of diaphragm,resulting in the protru-sion of abdominal organs into the thoracic *** estimated incidence of cdh is between 1 in 2000 and 1 in 5000 live births,although the true incidence is *** typically presents in childhood and can be diagnosed either pre-natally or ***,it can also be asymptomatic and carry the risk of developing into a life-threatening condition in *** SUMMARy A 76-year-old female with no history of prior abdominal surgeries presented for an elective colonoscopy for polyp *** the procedure,when approaching the hepatic flexure,the scope could not be advanced further despite multiple *** patient experienced mild abdominal discomfort,leading to the abortion of the *** in the recovery area,she developed increa-sing abdominal pains and *** abdominal imaging revealed her-niation of the proximal transverse colon through a Mh into the chest with evi-dence of *** patient underwent laparoscopic urgent colonic resection and primary hernia repair and was discharged uneventfully 2 d *** A Mh is a rare condition in adults that can present as a life-threatening compli-cation of colonoscopy,even in patients with a history of uneventful *** case highlights the importance of considering congenital and internal hernias when faced with sudden and unexplained difficulties during *** there is a suspicion of Mh,the endoscopist should halt the procedure and immediately obtain abdominal imaging to confirm the diagnosis.

关键词： Bowel perforation colonoscopy Adverse event congenital diaphragmatic

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蜂花粉中多酚类化合物的研究进展

中国蜂业 2024年第4期75卷 36-42页

作者：蔡雯雯(编译) 董捷乔(编译) 江涛(编译) Qiao j zhang y haubruge E 哈尔滨商业大学食品工程学院哈尔滨150076 资源昆虫高效养殖与利用全国重点实验室中国农业科学院蜜蜂研究所北京100093 不详

蜂花粉是由蜜蜂采集加工而成的花粉团状物,其富含大量的生物活性物质,包括多糖、蛋白质、脂质、多酚等,具有较高的药用功效和食用价值。多项研究表明多酚类化合物具有特定的抗氧化、抗菌、抗糖尿病、抗高血脂以及抗炎等作用。蜂花粉的... 详细信息

蜂花粉是由蜜蜂采集加工而成的花粉团状物,其富含大量的生物活性物质,包括多糖、蛋白质、脂质、多酚等,具有较高的药用功效和食用价值。多项研究表明多酚类化合物具有特定的抗氧化、抗菌、抗糖尿病、抗高血脂以及抗炎等作用。蜂花粉的多酚类化合物,特别是酚胺和黄酮苷已成为近期研究重点,也是蜂花粉发挥重要活性功能的主要成分。本文综述了近年来世界各地不同种类的蜂花粉中多酚类化合物的成分及含量,为蜂花粉后续研究提供参考。

关键词：蜂花粉多酚含量

An electropenetrography waveform library for the probing and ingestion behaviors of culex tarsalis on human hands

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Insect Science 2024年第4期31卷 1165-1186页

作者： Anastasia M.w.cooper Samuel B.jameson Victoria Pickens cameron Osborne Elaine A.Backus Kristopher Silver dana n.Mitzel department of Entomology Kansas State UniversityManhattanKansasUSA department of Tropical Medicine Tulane University School of Public Health and Tropical MedicineNew OrleansLos AngelesUSA USdA Agricultural Research Service San Joaquin Valley Agricultural Sciences CenterParlierCaliforniaUSA national Bio and Agro-defense Facility USDA Agricultural Research ServiceManhattanKansasUSA

culex tarsalis coquillett(diptera:culicidae)mosquitoes are capable of vectoring numerous pathogens affecting public and animal ***,the probing behaviors of mosquitoes are poorly understood because they occur in opaque ***(EPG)has the potential to elucidate these behaviors by recording the electrical signals generated during *** used an Ac–dc EPG with variable input resistors(Ri levels)to construct a waveform library for *** feeding on human *** events associated with mosquito probing were used to characterize waveforms at four Ri levels and with two electrical current *** optimal settings for EPG recordings of *** probing on human hands was an Ri level of 10^(7)Ohms using an applied signal of 150 millivolts alternating *** for *** included those previously observed and associated with probing behaviors in Aedes aegypti l.(diptera:culicidae):waveform families j(surface salivation),K(stylet penetration through the skin),l(types 1 and 2,search for a blood vessel/ingestion site),M(types 1 and 2,ingestion),n(type 1,an unknown behavior which may be a resting and digestion phase),and w(withdrawal).however,we also observed variations in the waveforms not described in ***,which we named types l3,M3,M4,and *** investigation enhances our understanding of mosquito probing *** also provides a new tool for the automated calculation of peak *** work will facilitate future pathogen acquisition and transmission studies and help identify new pest and disease management targets.

关键词： Ac-dc blood feeders electrical penetration graph EPG human hands mosquitoes waveform library

Mechanocatalysis of cO to cO_(2)on TiO_(2)surface controlled at atomic scale

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nano Research 2024年第7期17卷 5826-5834页

作者： yuuki Adachi Robert Turanský ján Brndiar Kamil Tokár Qiang zhu huan Fei wen yasuhiro Sugawara IvanŠtich yan jun li department of Applied Physics Osaka University2-1 YamadaokaSuitaOsaka 565-0871Japan Institute of Physics Slovak Academy of SciencesBratislava 84511Slovakia Institute of Informatics Slovak Academy of SciencesBratislava 84507Slovakia Faculty of natural Sciences University of Ss.Cyril and MethodiusTrnava 91701Slovakia Key laboratory of Instrumentation Science and dynamic Measurement School of Instrument and ElectronicsNorth University of ChinaTaiyuan 030051China

The common ways to activate a chemical reaction are by heat,electric current,or ***,mechanochemistry,where the chemical reaction is activated by applied mechanical force,is less common and only poorly understood at the atomic *** we report a tip-induced activation of chemical reaction of carbon monoxide to dioxide on oxidized rutile TiO_(2)(110)*** activation is studied by atomic force microscopy,Kelvin probe force microscopy under ultrahigh-vacuum and liquid nitrogen temperature conditions,and density functional theory(dFT)*** reaction is inferred from hysteretic behavior of frequency shift signal further supported by vector force mapping of vertical and lateral forces needed to trigger the chemical reaction with torque motion of carbon monoxide towards an oxygen *** reaction is found to proceed stochastically at very small tip-sample ***,the local contact potential difference reveals the atomic-scale charge redistribution in the reactants required to unlock the *** results open up new insights into the mechanochemistry on metal oxide surfaces at the atomic scale.

关键词： atomic resolution mechanochemistry atomic force microscopy Kelvin probe force microscopy density functional theory(dFT)simulation cO oxidation catalysis rutile TiO_(2)surface

Synthesis of coral-like structures of Pr-yb co-doped yIG: Structural,optical, magnetic and antimicrobial properties

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journal of Rare Earths 2024年第3期42卷 543-554,I0004页

作者： A.Fernandez Francisca P.Araujo y.Guerra S.castro-lopes j.Matilla-Arias Idglan S.de lima Edson c.Silva-Filho josy A.Osajima F.Guerrero R.Pena-Garcia Federal University of Piau Graduate Program in Materials Science and EngineeringTeresinaPIBrazil Federal Rural University of Pernambuco Academic Unit of Cabo de Santo AgostinhoCabo de Santo AgostinhoPEBrazil Federal University of Piaui Department of PhysicTeresinaPBrazil Federal University of Pernambuco Graduate Program in Materials ScienceRecifePEBrazil University of Granma Departmentof Basic Sciences and Applied InformaticsFaculty of Technical SciencesBayamoCuba Federal University of Amazonas Department of PhysicManausAMBrazil Federal University of Pernambuco Department of PhysicRecifePEBrazil

coral-like structures of the y_(3-x)Pr_(x)Fe_(5-y)yb_(y)O_(12),(0.00 ≤ x ≤ 0.04, 0.00 ≤ y ≤ 0.02) compound were synthesized using the sol-gel method. Structural investigation certified the yIG cubic crystal structure formation, without any secondary phase. It is shown that, the relatively large ionic radius of the dopant cations results in an expansion of the lattice parameter, variations in the Iona-O-Iondangle, Iona-O,Iond-O and Ionc-O bond distances and decrease in the average crystallite size. Fourier transform infrared(FTIR) and Raman measurements are essential to testify the single-phase formation of yIG crystal structure and are observed changes in the stretching and vibrational modes, respectively. The morphological study, energy dispersive spectroscopy(EdS) spectra and textural properties show corallike structures, peaks associated with Pr^(3+) and yb^(3+) atoms and the effect of dopants on surface area,diameter, and pore volume, respectively. The optical analysis from diffuse reflectance spectra witnessed an increase in the optical gap band, a decrease in Urbach energy and blue shift in the charge transfer,correlated with the expansion of the unit cell due to the dopant's insertion in the yIG structure. A typical ferrimagnetic behavior is exhibited by the y_(3-x)Pr_(x)Fe_(5-y)yb_(y)O_(12)compound. The saturation magnetization(M_(s)), cubic anisotropy constant(K_(1)) and coercive field(h_(c)) increase with the Pr^(3+)cations content, as consequence of their magnetic nature and distribution around of Fe^(3+)ions due to the coexistence with the yb^(3+). Finally, for the first time, antibacterial tests by mean of the direct contact method were performed for yIG co-doped with Pr^(3+)and yb^(3+)and it is shown that, relatively high dosages of Pr^(3+) cations favored the activity against S. aureus, therefore, a new biological property for yIG doped with rare earths is presented.

关键词： yttrium iron garnet(yIG) coral-like structures Rare earths Band gap energy Magnetic properties Antimicrobial properties

The hIF-1α/PlOd2 axis integrates extracellular matrix organization and cell metabolism leading to aberrant musculoskeletal repair

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Bone Research 2024年第2期12卷 289-301页

作者： heeseog Kang Amy l.Strong yuxiao Sun lei Guo conan juan Alec c.Bancroft ji hae choi chase A.Pagani Aysel A.Fernandes Michael woodard juhoon lee Sowmya Ramesh Aaron w.james david hudson Kevin n.dalby lin Xu Robert j.Tower Benjamin levi center for Organogenesis Regeneration and TraumaDepartment of SurgeryUniversity of Texas SouthwesternDallasTX 75390USA Section of Plastic Surgery Department of SurgeryUniversity of MichiganAnn ArborMI 48109USA Quantitative Biomedical Research center Peter O’Donnell Jr.School of Public HealthUniversity of Texas SouthwesternDallasTX 75390USA department of Orthopedics and Sports Medicine University of WashingtonSeattleWA 98195USA division of chemical Biology and Medicinal chemistry College of PharmacyUniversity of Texas at AustinAustinTX 78712USA department of Pathology Johns Hopkins UniversityBaltimoreMD 21218USA

while hypoxic signaling has been shown to play a role in many cellular processes,its role in metabolism-linked extracellular matrix(EcM)organization and downstream processes of cell fate after musculoskeletal injury remains to be ***(hO)is a debilitating condition where abnormal bone formation occurs within extra-skeletal *** andhypoxia-inducible factor 1α(hIF-1α)activation have been shown to promote ***,the underlying molecular mechanisms bywhich the hIF-1αpathway in mesenchymal progenitor cells(MPcs)contributes to pathologic bone formation remain to ***,we used a proven mouse injury-induced hO model to investigate the role of hIF-1αon aberrant cell ***-cell RnA sequencing(scRnA-seq)and spatial transcriptomics analyses of the hO site,we found that collagen EcM organizationis the most highly up-regulated biological process in *** mesenchymal cell-specific deletion of hif1α(hoxa11-creER^(T2);hif1a^(fl/fl))significantly mitigated hO in ***-seq analysis of these hoxa11-creER^(T2);hif1a^(fl/fl)mice identified the PlOd2/lOXpathway for collagen cross-linking as downstream of the hIF-1αregulation of ***,our scRnA-seq data and mechanisticstudies further uncovered that glucose metabolism in MPcs is most highly impacted by hIF-1α*** a translational aspect,a pan-lOX inhibitor significantly decreased hO.A newly screened compound revealed that the inhibition of PlOd2 activity in MPcssignificantly decreased osteogenic differentiation and glycolytic *** suggests that the hIF-1α/PlOd2/lOX axis linked tometabolism regulates hO-forming MPc *** results suggest that the hIF-1α/PlOd2/lOX pathway represents a promisingstrategy to mitigate hO formation.

关键词： metabolism skeletal aberrant

The neglect of nonnative orthopterans as potential invaders:A call for awareness

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Insect Science 2024年第4期31卷 994-1000页

作者： Anna K.Kulessa Paride Balzani Ismael Soto Antonín Kouba david Renault Ali Serhan Tarkan Phillip j.haubrock Ruhr University Bochum Faculty of Biology and BiotechnologyBochumGermany Faculty of Biology University of Duisburg-EssenUniversitätsstraße 5EssenGermany Faculty of Fisheries and Protection of waters South Bohemian Research Center of Aquaculture and Biodiversity of HydrocenosesUniversity of South Bohemia in CˇeskéBudeˇjoviceVodnˇanyCzech Republic University of Rennes CNRSECOBIO(EcosystèmesBiodiversitéEvolution)UMRRennesFrance Faculty of Fisheries Department of Basic SciencesMu˘gla SıtkıKoçman UniversityMu˘glaTurkey department of life and Environmental Sciences Bournemouth UniversityPooleDorsetUK Faculty of Biology and Environmental Protection Department of Ecology and Vertebrate ZoologyUniversity ofŁodzŁodzPoland department of River Ecology and conservation Senckenberg Research Institute and Natural History Museum FrankfurtGelnhausenGermany center for Applied Mathematics and Bioinformatics Gulf University for Science and TechnologyMubarak Al-AbdullahKuwait

despite the potential ecological and economic impacts of invasive species,there is a dearth of data on the presence,impacts,and management implications of potentially invasive Orthoptera *** lack of research and inconsistent data,including risk screenings and impact assessments,is especially evident in ***,assessing the status,distribution,and potential threats of nonnative Orthoptera in Europe remains challenging,impeding the development of effective management *** address this gap,we call for increased efforts to collect and curate data on non-native and possibly invasive Orthoptera in *** efforts will improve our understanding of this order’s invasion dynamics,facilitate the identification of priority areas for conservation,and support the development of effective management policies and preventive measures.

关键词： costs cricket damages grasshopper impact research

Academic productivity correlates with industry earnings in foot and ankle fellowship programs in the United States:A retrospective analysis

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world journal of Orthopedics 2024年第2期15卷 129-138页

作者： Albert T Anastasio Anthony n Baumann Kempland c walley Kyle j hitchman conor O’neill jonathan Kaplan Samuel B Adams department of Orthopedic Surgery Duke University HospitalDurhamNC 27710United States college of Medicine Northeast Ohio Medical UniversityRootstownOH 44272United States department of Orthopedic Surgery University of MichiganAnn ArborMI 48109United States School of Osteopathic Medicine Campbell UniversityLillingtonNC 27546United States

BAcKGROUnd The study investigates the connection between academic productivity and industry earnings in foot and ankle orthopedic surgery *** metrics like the h-index and Open Payments database(OPd)data,it addresses a gap in understanding the relationship between scholarly achievements and financial outcomes,providing a basis for further exploration in this specialized medical *** To elucidate the trends between academic productivity and industry earnings across foot and ankle orthopedic surgery fellowship programs in the United *** This study is a retrospective analysis of the relationship between academic productivity and industry earnings of foot and ankle orthopedic surgery fellowships at an individual faculty and fellowship *** productivity was defined via h-index and recorded from the Scopus *** earnings were recorded from the *** Forty-eight foot and ankle orthopedic surgery fellowships(100%of fellowships)in the United States with a combined total of 165 physicians(95.9%of physicians)were *** individual physician(n=165)total life-time earnings reported on the OPd website was United States dollar(USd)451430.30±1851084.89(range:USd 25.16-21269249.85;median:USd 27839.80).Mean physician(n=165)h-index as reported on Scopus is 14.24±12.39(range:0-63;median:11).There was a significant but weak correlation between individual physician h-index and individual physician total life-time earnings(Pn’s rho=0.334)and a significant and moderate positive correlation between combined fellowship h-index and total life-time earnings per fellowship(P=0.004,Spearman’s rho=0.409).cOnclUSIOn There is a significant and positive correlation between academic productivity and industry earnings at foot and ankle orthopedic surgery fellowships in the United *** observation is true on an individual physician level as well as on a fellowship level.

关键词： Sunshine act Foot and ankle Orthopedic surgery Orthopedic fellowship Industry earnings