检索结果-南通市图书馆

Reducing psychiatric illness in the perinatal period:A review and commentary

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

World Journal of Psychiatry 2023年第4期13卷 149-160页

作者： Jessica Rohr Farhaan S Vahidy Nicole Bartek Katelynn A Bourassa Namrata R Nanavaty Danielle D Antosh Konrad P harms Jennifer l Stanley Alok Madan Department of Psychiatry and Behavioral Health Houston MethodistHoustonTX 77030United States Department of Neurosurgery Houston MethodistHoustonTX 77030United States Department of Obstetrics and Gynecology Houston MethodistHoustonTX 77030United States

This brief overview highlights the global crisis of perinatal psychiatric illness(PPI).PPI is a major contributor to many adverse pregnancy,childbirth,and childhood development *** contributes to billions of dollars in spending worldwide each year and has a significant impact on the individual,their family,and their *** is also highly *** recommendations for intervention and management of PPI are limited and vary considerably from country to ***,there are several significant challenges associated with implementation of these *** challenges are magnified in number and consequence among women of color and/or minority populations,who experience persistent and negative health disparities during pregnancy and the postpartum *** paper aims to provide a broad overview of the current state of recommendations and implementation challenges for PPI and layout a framework for overcoming these *** equityinformed model of care that provides universal intervention for pregnant women may be one solution to address the preventable consequences of PPI on child and maternal ***,this model emphasizes the importance of managing and eliminating known barriers to traditional health care *** and contextually specific challenges must be overcome to fully realize the impact of improved management of PPI.

关键词： Perinatal psychiatric illness Postpartum depression Equity-oriented care Minority populations Maternal mortality Pregnancy

“Autoinflammatory psoriasis”-genetics and biology of pustular psoriasis

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2021年第2期18卷 307-317页

作者： Ranjitha Uppala lam C.Tsoi Paul W.harms Bo Wang Allison C.Billi Emanual Maverakis J.Michelle Kahlenberg Nicole l.Ward Johann E.Gudjonsson Graduate Program in Immunology University of MichiganAnn ArborMIUSA Department of Dermatology University of MichiganAnn ArborMIUSA Department of Pathology University of MichiganAnn ArborMIUSA Department of Dermatology University of CaliforniaDavisSacramentoCAUSA Division of Rheumatology Department of Internal MedicineUniversity of MichiganAnn ArborMIUSA A.Alfred Taubman Medical Research Institute Ann ArborMIUSA Departments of Nutrition and Dermatology Case Western Reserve UniversityClevelandOHUSA

Psoriasis is a chronic inflammatory skin condition that has a fairly wide range of clinical *** psoriasis,which is the most common manifestation of psoriasis,is located on one end of the spectrum,dominated by adaptive immune responses,whereas the rarer pustular psoriasis lies on the opposite end,dominated by innate and autoinflammatory immune *** recent years,genetic studies have identified six genetic variants that predispose to pustular psoriasis,and these have highlighted the role of Il-36 cytokines as central to pustular psoriasis *** this review,we discuss the presentation and clinical subtypes of pustular psoriasis,contribution of genetic predisposing variants,critical role of the Il-36 family of cytokines in disease pathophysiology,and treatment perspectives for pustular *** further outline the application of appropriate mouse models for the study of pustular psoriasis and address the outstanding questions and issues related to our understanding of the mechanisms involved in pustular psoriasis.

关键词： Pustular psoriasis Genetics Il-36 Autoinflammation Clinical features Histology

Effects of therapeutic horseback riding on post-traumatic stress disorder in military veterans

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Military Medical Research 2018年第1期5卷 19-32页

作者： Rebecca A.Johnson David l.Albright James R.Marzolf Jessica l.Bibbo Hayley D.Yaglom Sandra M.Crowder Gretchen K.Carlisle Amy Willard Cynthia l.Russell Karen Grindler Steven Osterlind Marita Wassman Nathan harms Research Center for Human Animal interaction College of Veterinary Medicine University of Missouri Columbia MO 65211 USA. ResearchService Harry S. Truman Memorial Veterans' Hospital ColumbiaMO 65211 USA. School of Social Work University of AlabamaTuscaloosa AL 35487 USA. Occupational Health Services Harry S. Truman Memorial Veterans' Hospital Columbia MO 65211 USA. Center for the Human-Animal Bond College of Veterinary MedicinePurdue University West Lafayette IN 47907 USA. School of Health Professions University of Missouri Columbia MO 65211 USA. TREE House of Greater St. louis Wentzville MO 63385 USA. School of Nursing and Health Studies University of Missouri-Kansas CityKansas City MO 64108 USA. Cedar Creek Therapeutic Riding Center Columbia MO 65201 USA. College of Education School and Counseling Psychology University of Missouri Columbia MO 65211USA. Ride-On St. louis Kimmswick MO 63053 USA.

Background:large numbers of post-deployment *** are diagnosed with post-traumatic stress disorder(PTSD)and/or traumatic brain injury(TBI),leading to an urgent need for effective interventions to reduce symptoms and increase veterans’*** includes anxiety,flashbacks,and emotional *** symptoms increase health care costs for stress-related illnesses and can make veterans’civilian life ***:We used a randomized wait-list controlled design with repeated measures of *** veterans to address our specific aim to test the efficacy of a 6-week therapeutic horseback riding(THR)program for decreasing PTSD symptoms and increasing coping self-efficacy,emotion regulation,social and emotional *** participants were recruited and 29 enrolled in the randomized *** were randomly assigned to either the horse riding group(n=15)or a wait-list control group(n=14).The wait-list control group experienced a 6-week waiting period,while the horse riding group began *** wait-list control group began riding after 6 weeks of participating in the control *** and health history information was obtained from all the *** symptoms were measured using the standardized PTSD Checklist-Military Version(PCl-M).The PCl-M as well as other instruments including,The Coping Self Efficacy Scale(CSES),The Difficulties in Emotion Regulation Scale(DERS)and The Social and Emotional loneliness Scale for Adults-short version(SElSA)were used to access different aspects of individual well-being and the PTSD ***:Participants had a statistically significant decrease in PTSD scores after 3 weeks of THR(P≤0.01)as well as a statistically and clinically significant decrease after 6 weeks of THR(P≤0.01).logistic regression showed that participants had a 66.7%likelihood of having lower PTSD scores at 3 weeks and 87.5%likelihood at 6 *** the generalized linear model(GlM),our ANOVA findings for the coping self

关键词： Animal-assisted intervention Coping self-efficacy Emotion regulation Military veterans Post-traumatic stress disorder Social engagement Therapeutic horseback riding Traumatic brain injury

An optimized derivative of an endogenous CXCR4 antagonist prevents atopic dermatitis and airway inflammation

在线全文

学校读者我要写书评

暂无评论

Acta Pharmaceutica Sinica B 2021年第9期11卷 2694-2708页

作者： Mirja harms Monica MWHabib Simona Nemska Antonella Nicolò Andrea Gilg Nico Preising Pandian Sokkar Sara Carmignani Martina Raasholm Gilbert Weidinger Gönül Kizilsavas Manfred Wagner ludger Ständker Ashraf HAbadi Hassan Jumaa Frank Kirchhoff Nelly Frossard Elsa Sanchez-Garcia Jan Münch Institute of Molecular Virology Ulm University Medical CenterUlm 89081Germany Department of Pharmaceutical Chemistry Faculty of Pharmacy and BiotechnologyGerman University in CairoCairo 11835Egypt laboratoire D'Innovation Thérapeutique UMR7200 CNRS/Universitéde Strasbourg and LabEx MEDALISFacultéde PharmacieIllkirch 67412France Institute of Immunology Ulm University Medical CenterUlm 89081Germany Core Facility Functional Peptidomics Ulm University Medical CenterUlm 89081Germany Center of Medical Biotechnology University of Duisburg-EssenDuisburg 47057Germany Max-Planck-Institute for Coal Research Düsseldorf 45470Germany Faculty of Allied Health Sciences Chettinad Hospital and Research InstituteChettinad Academy of Research and EducationKelambakkam 603103India Max-Planck-Institut für Molekulare Physiologie Dortmund 44227Germany Institute of Biochemistry and Molecular Biology Ulm UniversityUlm 89081Germany Max Planck Institute for Polymer Research Mainz 55128Germany

Aberrant CXCR4/CXCl12 signaling is involved in many pathophysiological processes such as cancer and inflammatory diseases.A natural fragment of serum albumin,named EPI-X4,has previously been identified as endogenous peptide antagonist and inverse agonist of CXCR4 and is a promising compound for the development of improved analogues for the therapy of CXCR4-associated *** generate optimized EPI-X4 derivatives we here performed molecular docking analysis to identify key interaction motifs of EPI-X4/*** rational drug design allowed to increase the anti-CXCR4 activity of *** EPI-X4 derivative JM#21 bound CXCR4 and suppressed CXCR4-tropic HIV-1 infection more efficiently than the clinically approved small molecule CXCR4 antagonist ***-X4 JM#21 did not exert toxic effects in zebrafish embryos and suppressed allergen-induced infiltration of eosinophils and other immune cells into the airways of animals in an asthma mouse ***,topical administration of the optimized EPI-X4 derivative efficiently prevented inflammation of the skin in a mouse model of atopic ***,rationally designed EPIX4 JM#21 is a novel potent antagonist of CXCR4 and the first CXCR4 inhibitor with therapeutic efficacy in atopic *** clinical development of this new class of CXCR4 antagonists for the therapy of atopic dermatitis,asthma and other CXCR4-associated diseases is highly warranted.

关键词： CXCR4 antagonist Asthma Allergy Inflammation Atopic dermatitis

在线全文

学校读者我要写书评

暂无评论

一种新型排液方法——对井口实施降压

海洋石油 2006年第1期26卷 96-100页

作者： harms l K 刘琦（译）蒋建勋（审）不详西南石油学院在读油气田开发工程硕士研究生

论述了在南得克萨斯州某油田的21口井安装井口压缩机装置取得了很好的排液效果。这些井安装了这种局部区域型低压集输系统后,气体的产量有了显著的提高,直接使油田获得了经济效益。还介绍了选井的条件和现场试验得到的经验与结论,可以... 详细信息

论述了在南得克萨斯州某油田的21口井安装井口压缩机装置取得了很好的排液效果。这些井安装了这种局部区域型低压集输系统后,气体的产量有了显著的提高,直接使油田获得了经济效益。还介绍了选井的条件和现场试验得到的经验与结论,可以对未来的工程起到预测和分析的作用。

关键词：井口压缩降压人工举升选井方法积液

饲料中食盐、钙和磷的含量对产蛋鸡生产性能的影响

在线全文

学校读者我要写书评

暂无评论

河南科技大学学报(农学版) 1981年 79-82页

作者： B.l.Damron R.H.harms 杨录臣

用纯种莱航小母鸡进行了两次试验(每次280天),将其分笼饲喂含不等量食盐、钙与磷的日粮,以研究对生产性能的影响。在补给的食盐和总钙量分别为0.18％、0.35％、0.7％和2.25％、3.5％、6.0％的情况下采用3×3因数排列组合法。当食盐和磷... 详细信息

用纯种莱航小母鸡进行了两次试验(每次280天),将其分笼饲喂含不等量食盐、钙与磷的日粮,以研究对生产性能的影响。在补给的食盐和总钙量分别为0.18％、0.35％、0.7％和2.25％、3.5％、6.0％的情况下采用3×3因数排列组合法。当食盐和磷都为变数时,上述食盐的三个因子再同0.45％或0.7％的磷组合,此时钙量为6％。试验表明,钙与食盐的变量组合对产蛋量有明显的影响,当食盐向0.7％递增时,产蛋量也一直在相应提高;含钙量为3.5％时,产蛋量比其2.25％或6.0％时更具有统计意义。0.18％和0.7％的食盐与2.25％和3。5％的钙可使饲料效率大大提高。不论是哪种含盐量,只要钙量增加,鸡采食量就明显减少。在食盐×磷组合试验中,食盐含量为0.35％时产蛋量显著提高。食盐及磷含量的变动对产蛋量也有特殊的意义。

关键词：食盐钙量饲粮氯化钠产蛋量生产性能

COVID-19:Reducing the risk via diet and lifestyle

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Medicine 2023年第1期21卷 1-16页

作者： Jessica l.Campbell 160 Goat Island Road LeighAuckland 0985New Zealand

This review shows that relatively simple changes to diet and lifestyle can significantly,and rapidly,reduce the risks associated with coronavirus disease 2019(COVID-19)in terms of infection risk,severity of disease,and even disease-related mortality.A wide range of interventions including regular exercise,adequate sleep,plant-based diets,maintenance of healthy weight,dietary supplementation,and time in nature have each been shown to have beneficial effects for supporting more positive health outcomes with COVID-19,in addition to promoting better overall *** paper brings together literature from these areas and presents the argument that non-pharmaceutical approaches should not be overlooked in our response to *** is noted that,in several cases,interventions discussed result in risk reductions equivalent to,or even greater than,those associated with currently available *** the balance of evidence suggests benefits,and the risk is minimal to none,it is suggested that communicating the power of individual actions to the public becomes morally ***,many lives could be saved,and many harms from the vaccine mandates avoided,if we were willing to embrace this lifestyle-centred approach in our efforts to deal with COVID-19.

关键词： COVID-19 SARS-CoV-2 Exercise Sleep Diet Risk reduction behaviour

Thoughts of a travelling ecologist 15. Are arthropods in decline and does it matter?

在线全文

学校读者我要写书评

暂无评论

生物安全学报 2019年第2期28卷 79-81页

作者： Gábor l.l?VEI Institute of Applied Ecology Fujian Agriculture and Forestry University Department of Agroecology Aarhus UniversityFlakkebjerg Research Centre

The world population continues to grow, although there are signs that the trend is slowing, and the human population may actually be facing a decline (Bricker & Ibbitson,2019). Nonetheless, the human impact is now so large that it threatens numerous other species. Recent assessments of the state of the natural world underlines that extinctions are not the only relevant criterion to indicate that the human race harms other beings: since 1970, the populations of an estimated 10,000 species of vertebrates declined by over half (WWF,2014). Another striking example of human influence on the living world is on bird abundance. Domesticated chicken ( Gallus gallus domesticus ) is today the world′s most numerous bird with a standing population of 22.7 billion (FAO,2018), which is an order of magnitude greater than the standing stock of the most abundant wild bird species, the red-billed quelea ( Quelea quelea ) at approximately 1.5 billion (Craig,2010).

关键词： population continues Nonetheless red-billed quelea

Exposure to dietary mercury alters cognition and behavior of zebra finches

在线全文

学校读者我要写书评

暂无评论

Current Zoology 2017年第2期63卷 213-219页

作者： John R SWADDlE Tessa R. DIEHl Capwell E, TAYlOR Aaron S. FANAEE Jessica l. BENSON Neil R. HUCKSTEP Daniel A. CRISTOl Biology Department College of William and Mary Institute for Integrative Bird Behavior Studies Williamsburg VA 23187-8795 USA Biological Sciences Virginia Tech 1405 Perry Street Blacksburg VA 24061 USA

Environmental stressors can negatively affect avian cognitive abilities, potentially reducing fitness, for example by altering response to predators, display to mates, or memory of locations of food. We expand on current knowledge by investigating the effects of dietary mercury, a ubiquitous en- vironmental pollutant and known neurotoxin, on avian cognition. Zebra finches Taeniopygia gut- tata were dosed for their entire lives with sub-lethal levels of mercury, at the environmentally rele- vant dose of 1.2 parts per million. In our first study, we compared the dosed birds with controls of the same age using tests of three cognitive abilities： spatial memory, inhibitory control, and color association. In the spatial memory assay, birds were tested on their ability to learn and remember the location of hidden food in their cage. The inhibitory control assay measured their ability to ig- nore visible but inaccessible food in favor of a learned behavior that provided the same reward. Finally, the color association task tested each bird＇s ability to associate a specific color with the presence of hidden food. Dietary mercury negatively affected spatial memory ability but not inhibi- tory control or color association. Our second study focused on three behavioral assays not tied to a specific skill or problem-solving： activity level, neophobia, and social dominance. Zebra finches exposed to dietary mercury throughout their lives were subordinate to, and more active than, con- trol birds. We found no evidence that mercury exposure influenced our metric of neophobia. Together, these results suggest that sub-lethal exposure to environmental mercury selectively harms neurological pathways that control different cognitive abilities, with complex effects on be- havior and fitness.

关键词： animal behavior ecotoxicology cognition mercury spatial memory zebra finch.