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Gut microbes limit growth in house sparrow nestlings(Passer domesticus)but not through limitations in digestive capacity

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Integrative Zoology 2018年第2期13卷 139-151页

作者： Kevin D.KOHl Antonio BRUN Seth R.BORDENSTEIN enrique CAVIEDES-vidal William H.KARASOV Department of Biological Sciences Vanderbilt UniversityNashvilleTennesseeUSA Department of Biological Sciences University of PittsburghPittsburghPennsylvaniaUSA Department of Forest and Wildlife Ecology University of Wisconsin-MadisonMadisonWisconsinUSA Department of Pathology Microbiologyand ImmunologyVanderbilt UniversityNashvilleTennesseeUSA Institute for Multidisciplinary Research in Biology of San luis National Scientific and Technical Research CouncilSan LuisArgentina Department of Biochemistry and Biological Sciences Universidad Nacional de San LuisSan LuisArgentina

Recent research often lauds the services and beneficial effects of host-associated microbes on ***,hosting these microbes may come at a *** example,germ-free and antibiotic-treated birds generally grow faster than their conventional *** the wild,juvenile body size is correlated with survival,so hosting a microbiota may incur a fitness *** altricial nestlings represent an interesting study system in which to investigate these interactions,given that they exhibit the fastest growth rates among vertebrates,and growth is limited by their digestive *** investigated whether reduction and restructuring of the microbiota by antibiotic treatment would:(i)increase growth and food conversion efficiency in nestling house sparrows(Passer domesticus);(ii)alter aspects of gut anatomy or function(particularly activities of digestive carbohydrases and their regulation in response to dietary change);and(iii)whether there were correlations between relative abundances of microbial taxa,digestive function and nestling *** treatment significantly increased growth and food conversion efficiency in *** did not alter aspects of gut anatomy that we considered but depressed intestinal maltase *** were no significant correlations between abundances of microbial taxa and aspects of host ***,we conclude that microbial-induced growth limitation in developing birds is not driven by interactions with digestive ***,decreased energetic and material costs of immune function or beneficial effects from microbes enriched under antibiotic treatment may underlie these *** the costs and tradeoffs of hosting gut microbial communities represents an avenue of future research.

关键词： antibiotics food conversion efficiency gut microbiota host-microbe interactions maltase

Daily expression of sodium-dependent glucose cotransporter-1protein in jejunum during rat ontogeny

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Animal Nutrition 2019年第3期5卷 290-296页

作者： Juan I.Baston Fabricio D.Cid enrique Caviedes-vidal Juan G.Chediack laboratorio de Fisiopatología Endometrial Instituto de Biología y Medicina Experimental(IByME)CONICETCiudad Autoonoma de Buenos AiresC1428ADNArgentina laboratorio de Biología Integrativa“Prof.E.Caviedes Codelia” Facultad de QuímicaBioquímica y FarmaciaUniversidad Nacional de San LuisSan LuisD5700HHWArgentina Instituto Multidisciplinario de Investigaciones en Biología-San luis(IMIBIO-Sl CCT-SL)CONICETSan Luis D5700HHWArgentina

It is widely known that intestinal capacities such as the enzymatic hydrolysis of carbohydrates,lipids and proteins,and the subsequent absorption of the hydrolyzed *** evolutionary matched to dietary loads and feeding *** this study,we demonstrate that the protein expression of apically located sodium-dependent glucose cotransporter-1(SGlT-1)throughout rat ontogeny is daily adjusted to afford glucose uptake when the load of this metabolically essential monosaccharide in the intestinal lumen is *** jejunal expression of SGlT-1 protein in 14 one-day-old suckling pups was found to increase at dark and early light phase(Pld and juvenile 28-d-old rats,the cotransporter expression was high throughout the entire day(Plly,adult 90-d-old rats showed a well-developed circadian rhythm for SGlT-1 protein(Plate light and dark phase when the highest intestinal glucose load was *** our knowledge,these results are the first reporting the daily profile of SGlT-1 expression during rat early developmental stage and may contribute to understand the biological significance of a well-established molecular capacity to deal with the crucial increase of glucose load in the diet during the weaning process.

关键词： Intestinal SGlT-1 Protein expression Daily rhythms Ontogeny Rat

Therapeutic potential of insulin-like growth factor 2 in Huntington's disease: controlling proteostasis to alleviate the load of misfolded protein

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Neural Regeneration Research 2021年第8期16卷 1564-1565页

作者： Paulina Troncoso-Escudero Claudio Hetz Rene l.vidal Biomedical Neuroscience Institute Faculty of MedicineUniversity of ChileSantiagoChile Center for Geroscience Brain Health and MetabolismSantiagoChile Program of Cellular and Molecular Biology Institute of Biomedical SciencesUniversity of ChileSantiagoChile Center for Integrative Biology Faculty of SciencesUniversity MayorChile Buck Institute for Research on Aging NovatoCAUSA

Huntington's disease(HD) is an inherited autosomal dominant neurodegenerative disorder characterized by the development of adult-onset motor dysfunction,psychiatric disturbances and intellectual *** is associated with an expansion of CAG repeat sequence in the huntingtin gene(Htt).Exon 1 of Htt normally contains between 6 to 35 CAG repeats,whereas in patients affected with HD it contains more than 40 trinucleotides.

关键词： Huntington Therapeutic stasis

CD300a inhibits CD16-mediated NK cell effector functions in HIV-1-infected patients

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Cellular & Molecular Immunology 2019年第12期16卷 940-942页

作者： Joana Vitallé Iñigo Terrén Ane Orrantia Raquel Pérez-Garay Francesc vidal JoséA.Iribarren Carmen Rodríguez Ana M.lópez lirola enrique Bernal Olatz Zenarruzabeitia Francisco Borrego Immunopathology Group Biocruces Bizkaia Health Research InstituteBarakaldoSpain Hospital Universitari de Tarragona Joan XXIII IISPVUniversitat Rovira i VirgiliTarragonaSpain Servicio de Enfermedades Infecciosas Hospital Universitario DonostiaInstituto de Investigación Sanitaria BiodonostiaDonostia-San SebastiánSpain Centro Sanitario Sandoval Hospital Clínico San CarlosInstituto de Investigación Sanitaria San CarlosMadridSpain Hospital Universitario de Canarias Santa Cruz de TenerifeSpain Department of Clinical Medicine Universidad de Murcia and Hospital General Universitario Reina SofíaMurciaSpain Ikerbasque Basque Foundation for ScienceBilbaoSpain

Natural killer(NK)cell-mediated antibody-dependent cellular cytotoxicity(ADCC)through CD16 plays a critical role in antihuman immunodeficiency virus(HIV)responses.1–3 CD300a is a surface receptor highly expressed on NK cells that has the capacity to inhibit NK cell-mediated cytotoxicity in healthy donors.4 The CD300a molecule has been related to several viral infections and is able to diminish the NK cell killing of pseudorabies-infected cells through interactions with its ligands phosphatidylserine and phosphatidylethanolamine.5 In addition,CD300a expression on B and CD4+T lymphocytes is altered during HIV-1 infection,and combined antiretroviral therapy(cART)does not restore nonpathological expression levels.5,6 However,the expression and function of CD300a on NK cells during HIV-1 infection is still *** have determined the surface expression of CD300a on different NK cell subsets and the capacity of this receptor to inhibit CD16-induced NK cell effector functions in healthy and HIV-1 infected individuals.

关键词： CD16 CD30 ADCC

Hybrid Triboelectric-Electromagnetic Nanogenerators for Mechanical Energy Harvesting:A Review

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Nano-Micro letters 2021年第12期13卷 163-220页

作者： Joao V.vidal Vladislav Slabov Andrei l.Kholkin Marco P.Soares dos Santos Department of Physics and CICECO-Aveiro Institute of Materials University of Aveiro3810-193 AveiroPortugal Department of Physics and I3N University of Aveiro3810-193 AveiroPortugal laboratory of Functional low-Dimensional Structures National University of Science and Technology MISISMoscowRussia Department of Mechanical Engineering Centre for Mechanical Technology and Automation(TEMA)University of Aveiro3810-193 AveiroPortugal

Motion-driven electromagnetictriboelectric energy generators(E-TENGs) hold a Hybrid triboelectric-electromagnetic generators C A Bgreat potential to provide higher voltages,higher currents and wider operating bandwidths than Cantilever generators1 μm both electromagnetic and triboelectric generators Rotating generatorsSliding generators standing alone. Therefore,they are promising solutions to autonomously supply a broad range of Flexible blade generators Magnetoelectric highly sophisticated devices. This paper provides generators a thorough review focused on major recent breaklinear generators Multidimensional generators throughs in the area of electromagnetic-triboelectric vibrational energy harvesting. A detailed Pendulum generators analysis was conducted on various architectures including rotational,pendulum,linear,sliding,cantilever,flexible blade,multidimensional and 1 cm magnetoelectric,and the following hybrid technologies. They enable highly e cient ways to harvest electric energy from many forms of vibrational,rotational,biomechanical,wave,wind and thermal sources,among others. Open-circuit voltages up to 75 V,short-circuit currents up to 60 mA and instantaneous power up to 144 mW were already achieved by these nanogenerators. Their transduction mechanisms,including proposed models to make intelligible the involved physical phenomena,are also overviewed here. A comprehensive analysis was performed to compare their respective construction designs,external excitations and electric outputs. The results highlight the potential of hybrid E-TENGs to convert unused mechanical motion into electric energy for both large-and small-scale ***,this paper proposes future research directions toward optimization of energy conversion e ciency,power management,durability and stability,packaging,energy storage,operation input,research of transduction mechanisms,quantitative standardization,system integration,miniaturization and multi-energy hybrid cells.

关键词： E-TENG Hybrid triboelectric-electromagnetic Nanogenerators Energy harvesting

Isla San Pedro Nolasco as a late Miocene intrusive record at the eastern margin of the Gulf of California:Insights from geological,geochemical and geochronological studies

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Geoscience Frontiers 2022年第3期13卷 100-114页

作者： l.A.Velderrain-Rojas J.R.vidal-Solano l.M.Alva-Valdivia R.Vega-Granillo M.lópez-Martinez Departamento de Geología División de Ciencias Exactas y NaturalesUniversidad de SonoraC.P.83000 HermosilloSonoraMexico laboratorio de Paleomagnetismo Instituto de GeofísicaUniversidad Nacional Autónoma de MéxicoCircuito de la Investigación CientíficaC.P.04510 MéxicoD.F.Mexico Departamento de Geología División de Ciencias de la TierraCentro de Investigación Científica y de Educación Superior de EnsenadaBaja CaliforniaMexico

Isla San Pedro Nolasco(ISPN)is a structural high bounded by inactive dextral oblique-slip faults in the east-central part of the Gulf of California rift zone and is composed of intrusive rocks not exposed on other Gulf of California *** we present the reconnaissance results from geological mapping,as well as first geochemical and geochronological data for the ISPN intrusive *** intrusive rocks compose a sheet-like body of intermediate and felsic composition intruded by an intermediate and acidic dike *** intrusive rocks(host and dikes)range in age from ca.9 Ma to 10 Ma(^(40)Ar/^(39)Ar)and show a hydrous ferromagnesian mineral association(amphibole and biotite)with a calc-alkalic and transitional *** hydrated mineralogical association has not been recognized in the coeval rocks along the onshore western margin of the North American plate(coastal Sonora).However,such hydrous mineralogical association is found in the coeval rift transitional volcanic rocks from the Baja California Microplate at Santa Rosalía and Bahía de losÁngeles–Bahía de lasÁ*** ISPN continental block,at least 40 km long,has been pulled apart by transtensional faulting of the late Miocene Gulf of California shear zone before the westward migration of the North America-Pacific plate boundary at ca.3–2 ***,ISPN became isolated as an island during the late Miocene flooding of the Gulf of California seaway.

关键词： PAC-NAM plate boundary Gulf of California Intrusive rocks Isla San Pedro Nolasco

Debaryomyces hansenii supplementation in low fish meal diets promotes growth,modulates microbiota and enhances intestinal condition in juvenile marine fish

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Journal of Animal Science and Biotechnology 2024年第1期15卷 253-276页

作者： Ignasi Sanahuja Alberto Ruiz Joana P.Firmino Felipe E.Reyes-lópez Juan B.ortiz-Delgado Eva Vallejos-vidal lluis Tort Dariel Tovar-Ramírez Isabel M.Cerezo Miguel A.Moriñigo Carmen Sarasquete Enric Gisbert Aquaculture Program Institute of Agrifood Research and Technology(IRTA)La Rapita 43540Spain Centro de Biotecnologia Acuicola Universidad de Santiago de ChileSantiagoChile Instituto de Ciencias Marinas de Andalucia(ICMAN-CSIC) Avda.Republica Saharaui no 2Campus Universitario Rio San PedroPuerto RealCadiz 11510Spain Nucleo de Investigaciones Aplicadas en Ciencias Veterinarias y Agronomicas Facultad de Medicina Veterinaria y AgronomiaUniversidad de Las AmericasSantiagoChile Department of Cell Biology Physiologyand ImmunologyUniversitat Autonoma de BarcelonaBarcelonaSpain Centro de Investigaciones Biologicas del Noroeste SC CIBNORLa PazMexico Department of Microbiology Instituto de Biotecnologia Y Desarrollo Azul(IBYDA)Faculty of SciencesUniversity of Malaga29010 MalagaSpain SCBI Bioinformatic UnitUniversity of Malaga29590 MalagaSpain

Background The development of a sustainable business model with social acceptance,makes necessary to develop new strategies to guarantee the growth,health,and well-being of farmed *** hansenii is a yeast species that can be used as a probiotic in aquaculture due to its capacity to i)promote cell proliferation and differen-tiation,ii)have immunostimulatory effects,iii)modulate gut microbiota,and/or iv)enhance the digestive *** provide inside into the effects of *** on juveniles of gilthead seabream(Sparus aurata)condition,we inte-grated the evaluation of the main key performance indicators coupled with the integrative analysis of the intestine condition,through histological and microbiota state,and its transcriptomic *** After 70 days of a nutritional trial in which a diet with low levels of fishmeal(7%)was supplemented with 1.1%of ***(17.2×10^(5) CFU),an increase of ca.12%in somatic growth was observed together with an improve-ment in feed conversion in fish fed a yeast-supplemented *** terms of intestinal condition,this probiotic modu-lated gut microbiota without affecting the intestine cell organization,whereas an increase in the staining intensity of mucins rich in carboxylated and weakly sulphated glycoconjugates coupled with changes in the affinity for certain lectins were noted in goblet *** in microbiota were characterized by the reduction in abundance of several groups of Proteobacteria,especially those characterized as opportunistic *** microarrays-based transcrip-tomic analysis found 232 differential expressed genes in the anterior-mid intestine of ***,that were mostly related to metabolic,antioxidant,immune,and symbiotic *** Dietary administration of *** enhanced somatic growth and improved feed efficiency param-eters,results that were coupled to an improvement of intestinal condition as histochemical and transcriptomic tools *** probiotic ye

关键词： Debaryomyces hansenii Intestine condition low fish meal diet Microbiota Transcriptomics Yeast probiotic

Experimental control of optical helicity in nanophotonics

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light(Science & Applications) 2014年第1期3卷 166-172页

作者： Nora Tischler Ivan Fernandez-Corbaton Xavier Zambrana-Puyalto Alexander Minovich Xavier vidal Mathieu l Juan Gabriel Molina-Terriza ARC Centre for Engineered Quantum Systems Department of Physics&AstronomyMacquarie UniversitySydneyNSW 2109Australia Department of Physics&Astronomy Macquarie UniversitySydneyNSW 2109Australia Nonlinear Physics Centre and Centre for Ultrahigh-bandwidth Devices for Optical Systems(CUDOS) Research School of Physics and EngineeringThe Australian National UniversityCanberraACT 0200Australia

An analysis of light–matter interactions based on symmetries can provide valuable insight,particularly because it reveals which quantities are conserved and which ones can be transformed within a physical *** this context,helicity can be a useful addition to more commonly considered observables such as angular *** question arises how to treat helicity,the projection of the total angular momentum onto the linear momentum direction,in practical *** this paper,we put forward a simple but versatile experimental treatment of *** then apply the proposed method to the scattering of light by isolated cylindrical nanoapertures in a gold *** allows us to study the helicity transformation taking place during the interaction of focused light with the *** particular,we observe from the transmitted light that the scaling of the helicity transformed component with the aperture size is very different to the direct helicity component.

关键词： helicity nanoaperture nanophotonics optics symmetry

The importance of the bite angle of metal(Ⅲ) salen catalysts in the sequestration of CO_(2) with epoxides in mild conditions

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Green Chemical Engineering 2022年第2期3卷 180-187页

作者： Anna vidal-lopez Sergio Posada-Perez Miquel Sola Valerio D'Elia Albert Poater Institut de Quimica Computacional i Catalisi and Departament de Quimica Universitat de GironaC/Maria Aurelia Capmany6917003GironaCataloniaSpain Department of Chemistry Universitat Autonoma de BarcelonaCerdanyola del VallesCatalonia08193Spain Department of Materials Science and Engineering School of Molecular Science and EngineeringVidyasirimedhi Institute of Science and Technology(VISTEC)21210PayupnaiWang ChanThailand

located in the middle of the fever to solve the problem of CO_(2)emissions in the environment,CO_(2)sequestration by reaction with epoxides is one of the key tools,as it not only fixes CO_(2),but also makes it functional by leading to cyclic ***,the results are focused specifically on the formation of cyclic organic carbonates catalyzed by metal-salen complexes,previously achieved with yttrium and scandium,that are compared with those of analogous complexes containing metals from the first transition series,such as cobalt or *** functional theory(DFT)calculations allow to determine whether this switch of metals will be feasible and provide the basis for instigating future experimental efforts in this *** calculations analyzing the structure and electronics of the catalysts allow us to give not only a clear picture of whether these catalysts will be efficient,but also allow us to assess which metal center is the most convenient and/or whether the catalytic reaction will occur under mild *** buried volume calculations with the SambVca packages shed light on the different catalytic pockets of monometallic first row transition metals *** III salen *** predictive catalysis results show that the bite O-M-O angle plays an essential role in the catalysis.

关键词： CO_(2)fixation Salen catalyst CO_(2)functionalization Cyclic carbonate DFT calculations Predictive catalysis