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Batch Active learning for Multispectral and Hyperspectral Image Segmentation Using Similarity Graphs

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Communications on Applied Mathematics and Computation 2024年第2期6卷 1013-1033页

作者： Bohan Chen Kevin Miller Andrea l.Bertozzi Jon Schwenk Department of Mathematics University of CaliforniaLos Angeles520 Portola PlazaLosAngeles90095CAUSA Oden Institute for Computational Engineering and Sciences University of Texas at Austin201 E 24th StAustin 78712TXUSA los Alamos National laboratory Los AlamosNM 87545USA

Graph learning,when used as a semi-supervised learning(SSl)method,performs well for classification tasks with a low label *** provide a graph-based batch active learning pipeline for pixel/patch neighborhood multi-or hyperspectral image *** batch active learning approach selects a collection of unlabeled pixels that satisfy a graph local maximum constraint for the active learning acquisition function that determines the relative importance of each pixel to the *** work builds on recent advances in the design of novel active learning acquisition functions(e.g.,the Model Change approach in arXiv:2110.07739)while adding important further developments including patch-neighborhood image analysis and batch active learning methods to further increase the accuracy and greatly increase the computational efficiency of these *** addition to improvements in the accuracy,our approach can greatly reduce the number of labeled pixels needed to achieve the same level of the accuracy based on randomly selected labeled pixels.

关键词： Image segmentation Graph learning Batch active learning Hyperspectral image

Implications for brainstem recovery from studies in primates after sensory loss from arm

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Neural Regeneration Research 2024年第3期19卷 479-480页

作者： Jamie l.Reed Hui-Xin Qi Jon H.Kaas Department of Psychology Vanderbilt UniversityNashvilleTNUSA

For decades,researchers have known that when neurons lose their activating inputs,they can atrophy and even *** example,removing sensory nerve inputs from the arm to the spinal cord after amputation or cutting the spinal nerves can shrink the post-synaptic target zones(e.g.,Woods et al.,2000).From touch receptors for the hand and arm,primary nerve afferents enter the spinal cord,and axons travel in the dorsal columns to target the cuneate nucleus(Cu)of the brainstem on the same side of the body(Figure 1).When sensory loss is unilateral,the overwhelming result is for the associated primary target zone to shrink in total size(cross-sectional area),as compared to the size of the opposite side.

关键词： brainstem shrink removing

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Use of donepezil for neurocognitive recovery after brain injury in adult and pediatric populations:a scoping review

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Neural Regeneration Research 2024年第8期19卷 1686-1695页

作者： Avery l.Miller Nathan K.Evanson J.Michael Taylor University of Cincinnati College of Medicine CincinnatiOHUSA Department of Pediatrics University of CincinnatiCincinnatiOHUSA Department of Neurology and Rehabilitation Medicine University of CincinnatiCincinnatiOHUSA Division of Pediatric Rehabilitation Medicine Cincinnati Children’s Hospital Medical CenterCincinnatiOHUSA Division of Neurology Cincinnati Children’s Hospital Medical CenterCincinnatiOHUSA

There are few pharmacologic options for the treatment of cognitive deficits associated with traumatic brain injury in pediatric *** inhibitors such as donepezil have been evaluated in adult patients after traumatic brain injury,but relatively less is known about the effect in pediatric *** goal of this review is to identify knowledge gaps in the efficacy and safety of acetylcholinesterase inhibito rs as a potential a djuvant treatment fo r neurocognitive decline in pediatric patients with traumatic brain *** queried PubMed to identify literature published from database inception thro ugh June 2023 desc ribing the use of donepezil in young adult traumatic brain injury and pediatric patients with predefined *** on preselected search criteria,340 unique papers we re selected for title and abstra ct ***-two reco rds were reviewed in full after eliminating preclinical studies and pape rs outside the scope of the *** adult traumatic brain injury,we review results from 14 papers detailing 227 subjects where evidence suggests donepezil is well tole rated and shows both objective and patient-reported efficacy for reducing cognitive *** children,3 pape rs report on 5 children recovering from traumatic brain injury,showing limited *** additional 15 pediatric studies conducted in populations at risk for cognitive dysfunction provide a broader look at safety and efficacy in 210 patients in the pediatric age *** its promise for efficacy in adults with traumatic brain injury and tole rability in pediatric patients,we believe further study of donepezil for children and adolescents with traumatic brain injury is warranted.

关键词： acetylcholinesterase inhibitor adult cognition donepezil pediatrics traumatic brain injury

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Experimental and numerical investigation to elucidate the fluid flow through packed beds with structured particle packings

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Particuology 2024年第6期89卷 218-237页

作者： Shirin Patil Christian Gorges Joel lòpez Bonilla Moritz Stelter Frank Beyrau Berend van Wachem laboratory of Technical Thermodynamics Otto-von-Guericke-Universität MagdeburgUniversitätsplatz 239106 MagdeburgGermany Chair of Mechanical Process Engineering Otto-von-Guericke-Universität MagdeburgUniversitätsplatz 239106 MagdeburgGermany

The present paper presents an experimental and numerical investigation of the dispersion of the gaseous jet flow and co-flow for the simple unit cell(SUC)and body-centred cubic(BCC)configuration of particles in packed *** experimental setup is built in such a way that suitable and simplified boundary conditions are imposed for the corresponding numerical framework,so the simulations can be done under very similar conditions as the ***,a porous plate is used for the co-flow to achieve the uniform velocity and the fully developed flow is ensured for the jet *** SUC and BCC particle beds consist of 3D-printed spheres,and the non-isotropy near the walls is mostly eliminated by placing half-spheres at the channel *** flow velocities are analysed directly at the exit of the particle bed for both beds over 36 pores for the SUC configuration and 60 pores for the BCC configuration,for particle Reynolds numbers of 200,300,and *** particle image velocimetry is experimentally arranged in such a way that the velocities over the entire region at the exit of the packed bed are obtained *** numerical method consists of a state-of-the-art immersed boundary method with adaptive mesh *** paper presents the pore jet structure and velocity field exiting from each pore for the SUC and BCC packed particle *** numerical and experimental studies show a good agreement for the SUC configuration for all flow *** the BCC configuration,some differences can be observed in the pore jet flow structure between the simulations and the experiments,but the general flow velocity distribution shows a good overall *** axial velocity is generally higher for the pores located near the centre of the packed bed than for the pores near the *** addition,the axial velocities are observed to increase near the peripheral pores of the packed *** behaviour is predominant for the BCC configuration as compared to t

关键词： Uniform particle packing Packed bed reactor Stereo particle image velocimetry Immersed boundary method

采用基于影像工作站的高级“预先读片者”工作流程的计算机辅助诊断结直肠腺瘤对于CT结肠成像读片的时间效率

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国际医学放射学杂志 2013年第1期 99-99页

作者： T.Mang G.Hermosillo M.Wolf l.bogoni M.Salganicoff V.Raykar 黄黎香 Department of Radiology Medical University of ViennaWaehringer Guertel 18-201090 ViennaAustria

目的采用一组低发病率队列,评价一种高级"预先读片者"工作流程的计算机辅助诊断的CT结肠成像(CTC)对≥6mm结直肠腺瘤的显示能力。方法一名放射科医师采用"预先读片者"工作流程的计算机辅助诊断技术,回顾性分析616例经结肠镜证实的CT结... 详细信息

目的采用一组低发病率队列,评价一种高级"预先读片者"工作流程的计算机辅助诊断的CT结肠成像(CTC)对≥6mm结直肠腺瘤的显示能力。方法一名放射科医师采用"预先读片者"工作流程的计算机辅助诊断技术,回顾性分析616例经结肠镜证实的CT结肠成像数据。计算机辅助诊断自动生成病变的影像,包括全部数据的二维(2D)和三维(3D)影像、病灶部位的交互式3D影像和2D多平面重组影像。每例病人的数据首先进行计算机辅助诊断,而后采用快速2D浏览方式评价结肠区的情况。在每例病人、每个息肉和每个腺瘤水平上对≥6mm的病灶计算其敏感性。统计学方法采用Fisher确切概率检验和McNemar检验。结果根据参考标准,在91例病人(91/616)中共检出131个≥6mm的息肉(92个腺瘤,39个非腺瘤)和2个癌灶。采用"预先读片者"工作流程的计算机辅助诊断,放射医生检测出了所有≥10mm的腺瘤(34/34)和癌灶。每例病人、每个息肉水平上对于≥6mm病灶的敏感度分别为84.3%(75/89)和83.2%(109/131),对于腺瘤的敏感度分别为89.1%(57/64)和85.9%(79/92)。总体的特异度为95.6%(504/527)。对每例病人的平均读片时间为3.1min。结论采用基于影像工作站的"预先读片者"工作流程的计算机辅助诊断算法的CT结肠成像,能够在较低发病率人群中明显缩短读片时间情况下准确发现结直肠腺瘤。

关键词：直肠腺瘤计算机辅助诊断计算机辅助技术结肠成像读片工作流程 CT

Translating Pathological Brain Activity Primers in Parkinson’s Disease Research

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Research 2024年第1期2023卷 735-752页

作者： Daniela Mirzac Svenja l.Kreis Heiko J.luhmann Gabriel Gonzalez-Escamilla Sergiu Groppa Movement Disorders and Neurostimulation Department of NeurologyFocus Program Translational NeuroscienceRhine Main Neuroscience NetworkUniversity Medical Center of the Johannes Gutenberg University Mainz55131 MainzGermany Institute of Physiology University Medical Center of the Johannes Gutenberg University Mainz55131 MainzGermany

Translational experimental approaches that help us better trace Parkinson’s disease(PD)pathophysiological mechanisms leading to new therapeutic targets are urgently *** this article,we review recent experimental and clinical studies addressing abnormal neuronal activity and pathological network oscillations,as well as their underlying mechanisms and *** aim is to enhance our knowledge about the progression of Parkinson's disease pathology and the timing of its symptom’s ***,we present mechanistic insights relevant for the generation of aberrant oscillatory activity within the cortico-basal ganglia *** summarize recent achievements extrapolated from available PD animal models,discuss their advantages and limitations,debate on their differential applicability,and suggest approaches for transferring knowledge on disease pathology into future research and clinical applications.

关键词： clinical knowledge insight

CT结肠成像:计算机辅助检测作为第二与同步阅片者对具有一定CT结肠成像经验的普通放射科医生诊断结肠息肉的影响

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国际医学放射学杂志 2014年第5期 491-491页

作者： T.Mang l.bogoni V.X.Anand D.Chandra A.J.Curtin A.S.lev-Toaff 孔祥 Department of Biomedical Imaging and Image-guided Therapy Medical University of ViennaWaehringer Guertel 18-201090ViennaAustria

摘要目的评估运用计算机辅助检测(CAD)作为第二和同步阅片者来帮助具一定的CT结肠成像(CTC)经验的放射科医生诊断结肠息肉的有效性。方法 7名具有一定CTC

关键词：结肠成像 CTC 放射科结肠息肉辅助检测 CT 计算机

Integration of multiple flexible electrodes for realtime detection of barrier formation with spatial resolution in a gut-on-chip system

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Microsystems & Nanoengineering 2024年第1期10卷 105-114页

作者： Mara lucchetti Gabriel Werr Sofia Johansson laurent Barbe léa Grandmougin Paul Wilmes Maria Tenje luxembourg Centre for Systems Biomedicine(lCSB) University of LuxembourgEsch-sur-Alzette L-4362Luxembourg Division of Biomedical Engineering Department of Materials Science and EngineeringScience for Life LaboratoryUppsala University75121 UppsalaSweden Department of life Sciences and Medicine Faculty of ScienceTechnology and MedicineUniversity of LuxembourgEsch-sur-Alzette L-4362Luxembourg

In healthy individuals,the intestinal epithelium forms a tight barrier to prevent gut bacteria from reaching blood *** study the effect of probiotics,dietary compounds and drugs on gut barrier formation and disruption,human gut epithelial and bacterial cells can be cocultured in an in vitro model called the human microbial crosstalk(HuMiX)gut-on-a-chip ***,we present the design,fabrication and integration of thin-film electrodes into the HuMiX platform to measure transepithelial electrical resistance(TEER)as a direct readout on barrier tightness in *** various aspects of the HuMiX platform have already been set in their design,such as multiple compressible layers,uneven surfaces and nontransparent materials,a novel fabrication method was developed whereby thin-film metal electrodes were first deposited on flexible substrates and sequentially integrated with the HuMiX system via a transfer-tape ***,to measure localized TEER along the cell culture chamber,we integrated multiple electrodes that were connected to an impedance analyzer via a *** further developed a dynamic normalization method because the active measurement area depends on the measured TEER *** fabrication process and system setup can be applicable to other barrier-on-chip *** a proof-of-concept,we measured the barrier formation of a cancerous Caco-2 cell line in real-time,which was mapped at four spatially separated positions along the HuMiX culture area.

关键词： barrier system multiple

Study on the dynamic mechanical properties of winding-block axial structure considering short circuit strain rate effect

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High Voltage 2024年第2期9卷 380-390页

作者： Xinyu Wang Ping Wang Jianghai Geng Zikang Zhang Fangcheng lü Shuguo Gao Hebei Provincial Key laboratory of Power Transmission Equipment Security Defense North China Electric Power UniversityBaodingChina State Grid Hebei Electric Power Research Institute ShijiazhuangChina

Transformers may suffer multiple short-circuit impacts during long-term operation,and axial instability is one of the typical types of serious accidents caused by short-circuit *** axial instability form of the winding-block structure is analysed,and the dynamic solution of the winding short-circuit electromagnetic force is obtained by estab-lishing the three-dimensional magnetic-circuit-force multi-physical field coupling simulation *** influence of strain rate on the cushion block constitutive equation is corrected,and the modified model is verified by short-circuit impact test and quasi-static *** research results show that for 110 kV 31.5 MVA transformers,the maximum electromagnetic axial resultant force of winding is 363.16 kN,and the ultimate tilt force is 1214.2 *** pre-tightening force configuration is accordingly recom-mended to range from 363.16 to 608.28 kN,which is narrowed by 18.49%compared with the static calculation method;Meanwhile,adding a logarithmic strain rate correction term to the classical constitutive equation of the cushion block can achieve a good correction of the stress-strain relationship with the coefficient of determination above 0.99,and the cushion block has a larger elastic modulus under high strain rate *** research results provide an important theoretical reference for the axial stability structure of transformers.

关键词： axial correction structure