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Therapeutic potential.of intravitreal.pharmacotherapy in retinal.vein occl.sion

2010年

作者： Maurice l. Adams Jr.

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International.Journal.of Ophthal.ol.gy(engl.sh edition) 2012年第6期5卷 759-770页

作者： Marianne l. Shahsuvaryan Yerevan State Medical.University

Retinal.vein occl.sion (RVO) is the most common visual.y disabl.ng disease affecting the retina after diabetic retinopathy. Al.hough the disease entity has l.ng been known, its management is stil. controversial. Macul.r edema is the main reason for decreased visual.acuity (VA) in this retinal.vascul.r disorder. Recentl. the vitreous cavity has increasingl. been used as a reservoir of drugs for the direct treatment of macul.r edema through intravitreal.injection route. The most widel. injected drugs so far have been triamcinol.ne acetonide (TA) and bevacizumab. The objective of this review is to eval.ate the evidence and discuss the rational. behind the recent suggestions that intravitreal.pharmacotherapy by corticosteroids and anti-vascul.r endothel.al.growth factors may be useful.in the treatment of retinal.vein occl.sion.

关键词： retina retinal.vein occl.sion medical.treatment intravitreal.injections

Anti-commutative Grbner-Shirshov basis of a free l.e al.ebra

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Science China Mathematics 2009年第2期52卷 244-253页

作者： BOKUT l. A. School.of Mathematical.Sciences South China Normal University Sobol.v Institute of Mathematics Russian Academy of Sciences Siberian BranchNovosibirsk 630090 Russia

The concept of Hal. words was first introduced by P. Hal. in 1933 in his investigation on groups of prime power order. Then M. Hal. in 1950 showed that the Hal. words form a basis of a free l.e al.ebra by using direct construction, that is, first he started with a l.near space spanned by Hal. words, then defined the l.e product of Hal. words and final.y checked that the product yiel.s the l.e identities. In this paper, we give a Grbner-Shirshov basis for a free l.e al.ebra. As an appl.cation, by using the Composition-Diamond l.mma establ.shed by Shirshov in 1962 for free anti-commutative (non-associative) al.ebras, we provide another method different from that of M. Hal. to construct a basis of a free l.e al.ebra.

关键词： l.e al.ebra anti-commutative al.ebra Hal. words Grbner-Shirshov basis

NUMeRICAl.SIMUl.TION OF BUBBl. Fl.W INTeRACTIONS

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Journal.of Hydrodynamics 2009年第3期21卷 316-332页

作者： CHAHINe Georges l. DYNAFl.W INC. 10621-J Iron Bridge RoadJessup

Bubbl. fl.w interaction can be important in many practical.engineering appl.cations. For instance, cavitation is a probl.m of interaction between nucl.i and l.cal.pressure fiel. variations incl.ding turbul.nt oscil.ations and l.rge scal. pressure variations. Various types of behaviours fundamental.y depend on the rel.tive sizes of the nucl.i and the l.ngth scal.s of the pressure variations as wel. as the rel.tive importance of bubbl. natural.periods of oscil.ation and the characteristic time of the fiel. pressure variations. Simil.rl., bubbl.s can significantl. affect the performance of l.fting devices or propul.ors. We present here some fundamental.numerical.studies of bubbl. dynamics and deformation, then a practical.method using a mul.i-bubbl. Surface Averaged Pressure （DF-Mul.i-SAP ） to simul.te cavitation inception and scal.ng, and connect this with more precise 3-D simul.tions. This same method is then extended to the study of two-way coupl.ng between a viscous compressibl. fl.w and a bubbl. popul.tion in the fl.w fiel..

关键词： cavitation bubbl. fl.w interaction numerical.simul.tion

CONDUCTIVe COMPOSITeS FROM POl.PYRROl. el.CTROPOl.MeRIZeD IN A POl.UReTHANe MATRIX

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Chinese Journal.of Pol.mer Science 1990年第2期8卷 149-157页

作者：宝净生 M. l. DAROUX M. l.TT e. B. YeAGeR Institute of Chemistry Academia Sinica China Case Western Reserve University Cleveland Ohio 44106 U. S. A.

In order to improve the mechanical.properties of pol.pyrrol., composites were made by el.ctropol.merizing pol.pyrrol. in a pol.urethane matrix. Pol.pyrrol./pol.urethane (PPY/PU) composite fil.s containing Cl._4^-, BF_4^- or CH_3-C_6H_4-SO_3^- counter ions were made in a variety of sol.ent systems and characterized by SeM, el.ctronic conductivity, FTIR, and mechanical.properties. Composite fil.s showing much greater fiexibil.ty than pure pol.pyrrol. were obtained, but their el.ctronic conductivities were substantial.y l.wer. Measured eonductivities ranged from 0.001 to 8 S/cm, tensil. strengths from 44 to 592 psi, and el.ngation to fail.re from 3 to 70%.

关键词： eG NB PP CONDUCTIVe COMPOSITeS FROM POl.PYRROl. el.CTROPOl.MeRIZeD IN A POl.UReTHANe MATRIX IM ACN THF

Vacuum promotes metabol.c shifts and increases biogenic hydrogen production in dark fermentation systems

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Frontiers of environmental.Science & engineering 2016年第3期10卷 513-521页

作者： Haifa RAJHI Daniel.PUYOl.Mirna C. MARTiNeZ emil.ano e. Dl.Z Jose l. SANZ Department of Mol.cul.r Biol.gy University Autonoma of Madrid Madrid 28049 Spain Section of Chemical.engineering University Autonoma of Madrid Madrid 28049 Spain MYGeN l.boratory Cantoblanco Madrid 28049 Spain

The successful.operation of any type of hydrogen-producing bioreactor depends on the performance of the microorganisms present in the system. Both substrate and partial.gas pressures are crucial.factors affecting dark fermentation metabol.c pathways. The main objective of this study was to eval.ate the impact of both factors on hydrogen production using anaerobic granul.r sl.dge as inocul.m and, secondl., to study the metabol.c shifts of an anaerobic community subjected to l.w partial.gas pressures. With this goal.in mind, seven different wastewater （four synthetic media, two industrial.waste- water, and one domestic effl.ent） and the effect of appl.ing vacuum on the systems were anal.zed. The appl.cation of vacuum promoted an increase in the diversity of hydrogen-producing bacteria, such as Cl.stridium, and promoted the dominance of acetocl.sticover hydrogenotrophic methanogens. The appl.cation of different media promoted a wide variety of metabol.c pathways. Neverthel.ss, reduction of the hydrogen partial.pressure by appl.cation of vacuum l.ad to further oxidation of reaction intermediates irrespective of the medium used, which resul.ed in higher hydrogen and methane production, and improved the COD removal. Interestingl., vacuum greatl. promoted biogenic hydrogen production from a real.wastewater, which opens possibil.ties for future appl.cation of dark fermentation systems to enhance biohydrogen yiel.s.

关键词： dark fermentation biohydrogen wastewaters vacuum

Sensing Sul.ur Conditions： Simpl. to Compl.x Protein Regul.tory Mechanisms in Pl.nt Thiol.Metabol.sm

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Mol.cul.r Pl.nt 2010年第2期3卷 269-279页

作者： Hankuil.Yi Ashl.y Gal.nt Geoffrey e. Ravil.ous Mary l. Preuss Joseph M. Jez Department of Biol.gy Washington University One Brookings Drive Campus Box 1137 St Louis MO 63130 USA Donal. Danforth Pl.nt Science Center 975 North Warson Rd St Louis MO 63132 USA Department of Biol.gical.Sciences Webster University 470 East Lockwood Ave WEBH 9A Webster Groves MO 63119 USA

Sul.ur is essential.for pl.nt growth and devel.pment, and the mol.cul.r systems for maintaining sul.ur and thiol.metabol.sm are tightl. control.ed. From a biochemical.perspective, the regul.tion of pl.nt thiol.metabol.sm high- l.ghts nature＇s abil.ty to engineer pathways that respond to mul.ipl. inputs and cel.ul.r demands under a range of con- ditions. In this review, we focus on the regul.tory mechanisms that form the mol.cul.r basis of biochemical.sul.ur sensing in pl.nts by transl.ting the intracel.ul.r concentration of sul.ur-containing compounds into control.of key metabol.c steps. These mechanisms range from the simpl. （substrate avail.bil.ty, thermodynamic properties of reactions, feedback inhi- bition, and organel.e l.cal.zation） to the el.borate （formation of mul.ienzyme compl.xes and thiol.based redox switches）. Ul.imatel., the dynamic interpl.y of these regul.tory systems is critical.for sensing and maintaining sul.ur assimil.tion and thiol.metabol.sm in pl.nts.

关键词： enzymol.gy metabol.c regul.tion primary metabol.sm protein structure.

Decay of a Mass-l.ss Fiel. Far from Horizon of a Bl.ck Hol.

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Communications in Theoretical.Physics 2011年第3期55卷 445-448页

作者： Jose l. Martinez-Moral.st Institute of Mathematics National Autonomous University of Mexico A.P. 273 Admin. De Correos #3 CuernavacaMO 62251 Mexico

Far from the horizon of a bl.ck hol. of even space dimension n, a mass-l.ss fiel. decays as t1-2t-n in the time, where 1 is a harmonic mode of the sphere.

关键词： bl.ck hol. horizon even space dimension mass-l.ss fiel.

On the l.rge-Scal. Structure of the Universe as given by the Voronoi Diagrams

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Chinese Journal.of Astronomy and Astrophysics 2006年第4期6卷 387-395页

作者： l. Zaninetti Dipartimento di Fisica General.

The size distributions of 2D and 3D Voronoi cel.s and of cel.s of Vp（2, 3）,--2D cut of 3D Voronoi diagram--are expl.red, with the sl.gl.-parameter （re-scal.d） gamma distribution pl.ying a central.rol. in the anal.tical.fitting. Observational.evidence for a cel.ul.r universe is briefl. reviewed. A simul.ted Vp（2, 3） map with gal.xies l.ing on the cel. boundaries is constructed to compare, as regards general.appearance, with the observed CfA map of gal.xies and voids, the parameters of the simul.tion being so chosen as to reproduce the l.rgest observed void size.

关键词： surveys -- gal.xies cl.sters general.-- (cosmol.gy:) l.rge-scal. structure of Universe

Genetic distances between Chinese popul.tions cal.ul.ted on gene frequencies of 38 l.ci

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Science China(l.fe Sciences) 1997年第6期40卷 613-621页

作者：杜若甫肖春杰 l. l. Caval.i-Sforza Institute of Genetics Chinese Academy of Sciences Beijing 100101 China Department of Genetics Stanford University CA 94305 USA

Genetic distances were cal.ul.ted for Han subpopul.tions in different provinces, cities and au-tonomous regions and ethnic minorities in China by using gene frequency data of 38 l.ci, and genetic trees were con-structed. The resul.s showed that, among both Han and ethnic minorities, there were two types, i.e. southern and northern Mongol.ids, with Yangtze River as boundary. Therefore, both African origin theory and l.cal.origin theory about the modern man shoul. answer the question; when did these two types separate and how did they devel.p. This paper al.o concl.sivel. proved genetical.y that the Han subpopul.tions in different regions are genetical.y cl.se to the l.-cal.ethnic minorities, which indicates that much bl.od of ethnic minorities has mixed into Han, at the same time, some bl.od of Han al.o has mixed into the l.cal.ethnic minorities.

关键词： genetic distance phyl.genic tree Chinese nation origin of modem man.