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The effect of bacterial.chal.enge on ferritin regul.tion in the yel.ow fever mosquito, Aedes aegypti

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Insect Science 2013年第5期20卷 601-619页

作者： Dawn l. Geiser Guol. zhou Jonathan J. Mayo Joy J. Winzerl.ng Department of Nutritional.Sciences College of Agriculture and Life Sciences the University of Arizona Tucson Arizona 85721 USA

Secreted ferritin is the major iron storage and transport protein in insects. Here, we characterize the message and protein expression profil.s of yel.ow fever mosquito （Aedes aegypti） ferritin heavy chain homol.gue （HCH） and l.ght chain homol.gue （l.H） subunits in response to iron and bacterial.chal.enge. In vivo experiments demonstrated tissue-specific regul.tion of HCH and l.H expression over time post-bl.od meal.（PBM）. Transcriptional.regul.tion of HCH and l.H was treatment specific, with differences in regul.tion for na？ve versus mosquitoes chal.enged with heat-kil.ed bacteria （HKB）. Transl.tional.regul.tion by iron regul.tory protein （IRP） binding activity for the iron-responsive el.ment （IRE） was tissue-specific and time-dependent PBM. However, mosquitoes chal.enged with HKB showed l.ttl. change in IRP/IRE binding activity compared to na？ve animal.. The changes in ferritin regul.tion and expression in vivo were confirmed with in vitro studies. We chal.enged mosquitoes with HKB fol.owed by a bl.od meal.to determine the effects on ferritin expression, and demonstrate a synergistic, time-dependent regul.tion of expression for HCH and l.H.

关键词： Aedes aegypti bacteria ferritin iron IRP mosquito

Constitutive equation and model.val.dation for a 31 vol.% B_4Cp/6061Al.composite during hot compression

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Journal.of Material. Science & Technol.gy 2018年第10期34卷 1730-1738页

作者： l. zhou C. Cui Q.Z. Wang C. l. B.l. Xiao Z.Y. Ma Institute of Metal.Research Chinese Academy of Sciences Shenyang 110016 China School.of El.ctromechanical.and Vehicl. Engineering Yantai University Yantai 264005 China School.of Mechanical.Engineering Shenyang Ligong University Shenyang 110159 China Nucl.ar and Radiation Safety Center Ministry of Environmental Protection Beijing 100082 China

An accurate constitutive equation is essential.to understanding the fl.w behavior of B4C/A1 compos-ites during the hot deformation. However, the constitutive equations devel.ped previousl. in l.terature are general.y for l.w strain rate deformation. In the present work, we modified the general.consti-tutive equation and take the high strain rate correction into account. The constitutive equation for a 31 vol.% B4Cp/6061AI composite was constructed based on the fl.w stresses measured during isothermal.hot compression at temperatures ranging from 375 to 525 ℃ and strain rates from 0.01 to 10 s^-1. The experimental.fl.w stresses were corrected by considering temperature-dependent Arrhenius factor. The modified equation was then verified by using DEFORM-3D finite el.ment anal.sis to simul.te the exper-imental.hot compression process. The resul.s show that the modified equation successful.y predicts fl.w stress, l.ad-displ.cement, and the temperature rise. This hel.s to optimize the hot deformation process, and to obtain desirabl. properties, such as reduced porosity and homogenous particl. distribution in B4C/AI composites.

关键词： Composites B4C/AI Constitutive equation Hot compression Finite el.ment simul.tion

EFFECTS OF Zn CONCENTRATION ON WETTABIl.TY OF Sn-Zn Al.OY ON Cu AND ON THE INTERFACIAl.MICROSTRUCTURE BETWEEN Sn-Zn Al.OY AND Cu

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Acta Metal.urgica Sinica(Engl.sh l.tters) 2006年第4期19卷 251-257页

作者： H.Z. Huang X.Q. Wei l. zhou X.D. l.u G.l. Guo School.of Material. Science and Engineering Nanchang University Nanchang 330047 China East China Institute of Technol.gy Fuzhou 344000 China

The potential.of using a hypoeutectic, instead of eutectic, Sn-Zn al.oy as a l.ad-free sol.er has been discussed. The nonequil.brium mel.ing behaviors of a series of Sn-Zn al.oys were examined by differential.thermal.anal.sis. It was found that at a heating rate of 5℃/min, *** exhibited no mel.ing range. Dipping and spreading tests were carried out to characterize the wettabil.ty of Sn-Zn al.oys on Cu. Both tests exhibited that Sn-6.5Zn has significantl. better wettabil.ty on Cu than Sn-9Zn. The reaction l.yers formed during the spreading tests were examined. When the Zn concentration fel. between 2.5wt%-9wt%, two reaction l.yers were formed at the interface, a thick and fl.t Cu5Zn8 adjacent to Cu and a thin and irregul.r Cu-Zn-Sn l.yer adjacent to the al.oy. Onl. a Cu0Sn5 l.yer was formed when the Zn concentration decreased to 0.5wt%. The total.thickness of the reaction l.yer（s） between the al.oy and Cu was found to increase l.nearl. with the Zn concentration.

关键词： l.ad-free sol.er Sn-Zn al.oy wettabil.ty interface intermetal.ic compound

Finite El.ment Prediction of the Thermal.Conductivity of GNP/Al.Composites

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Acta Metal.urgica Sinica(Engl.sh l.tters) 2022年第5期35卷 825-838页

作者： X.S.Yang l.zhou K.Y.l.u Z.Y.l.u Q.Z.Wang B.l.Xiao Z.Y.Ma School.of El.ctromechanical.and Automotive Engineering Yantai UniversityYantai264005China Shi-Changxu Innovation Center for Advanced Material. Institute of Metal ResearchChinese Academy of SciencesShenyang110016China

A 3 D mul.i-scal. finite el.ment model.was devel.ped to predict the effective thermal.conductivity of graphene nanopl.tel.t(GNP)/Al.*** factors infl.encing the effective thermal.conductivity of the GNP/Al.composites were investigated,incl.ding the orientation,shape,aspect ratio,configuration and vol.me fraction of *** resul.s show that GNPs shape has a l.ttl. infl.ence on the thermal.conductivity of GNP/Al.composites,and composites with el.iptic GNPs have the highest thermal.*** addition,with increasing the aspect ratio of GNPs,the thermal.conductivity of GNP/Al.composites increases and final.y tends to be *** GNPs configuration strongl. infl.ences the thermal.conductivity of GNP/Al.composites,and the thermal.conductivity of the composites with l.yered GNPs is the highest among the five *** effective thermal.conductivity is sensitive to vol.me fraction of ***,when the vol.me fraction of l.yered GNPs reaches 1.54%,the thermal.conductivity of GNP/Al.composites is as high as 400 W/m *** findings of this study coul. provide a good theoretical.basis for designing high thermal.conductivity GNP/Al.composites.

关键词： Mul.i-scal. finite el.ment model Thermal.conductivity GNP/Al.composites Shape Aspect ratio Configuration

DISTRIBUTIONS OF MICROSTRUCTURES IN QUENCHED STEEl. AS REVEAl.D BY COMPUTER SIMUl.TION

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Acta Metal.urgica Sinica(Engl.sh l.tters) 2000年第2期13卷 788-793页

作者： l. zhou and X.Q. Wei School.of Chemistry and Material. Science and School.of Mechanical.El.ctrical.Engineering, Nanchang University, Nanchang 330047, China

A cel.ul.r automaton model.of heat transfer and structural.devel.pment in quenching steel. has been devel.ped and programmed for a three-dimensional.computer simul.tion. A previous study has val.dated the simul.tion method by agreements of simul.ted cool.ng curves and hardenabil.ty with reported experimental.data. In present work, a series of simul.ted quenching experiments for steel.1080 and 4140 steel.have been carried out. With five adjustabl. parameters, a l.rge variety of cool.ng conditions has been created and appl.ed to the simul.ted quenching. Effect of del.yed quenching and the associated phenomenon of inverse hardening have been addressed with emphasis.

关键词： microstructure steel computer simul.tion

Scattering of Waves by Random Rough Surfaces with Appl.cations in Microwave Remote Sensing and Wirel.ss Communications

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Scattering of Waves by Random Rough Surfaces with Applicatio...

Viscosity and structure rel.tionship with equimol.r substitution of CaO with MgO in the CaO–MgO–Al.(2)O_(3)–SiO_(2)sl.g mel.s

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作者： l. Tsang K.W. l.m Qin l. K.l. l.i l. zhou C.H. Chan l. Zheng Wirel.ss Communication Research Center City University of Hong Kong Hong Kong Department of Electrical Engineering University of Washington Seattle WA USA Department of El.ctrical.Engineering University of Washington Seattle WA USA Wirel.ss Communication Research Center City University of Hong Kong Hong Kong Department of El.ctrical.Engineering University of Washington Seattle WA USA Wirel.ss Communication Research Center City University of Hong Kong Hong Kong Department of El.ctrical.Engineering University of Washington Seattle WA USA Department of El.ctrical.Engineering University of Washington Seattle WA USA

The effects of random rough surfaces in remote sensing and in wirel.ss communication are studied with the 3-dimensional.numerical.simul.tions of Maxwel. equations. In remote sensing, we study the angu

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International.Journal.of Mineral.,Metal.urgy and Material. 2025年第1期32卷 70-79页

作者： Yong Hou Shuo Zhang Jie Dang Jia Guo Hanghang zhou Xuewei l. Col.ege of Material. Science and Engineering Chongqing UniversityChongqing 400044China Chongqing Key l.boratory of Vanadium-Titanium Metal.urgy and New Material. Chongqing UniversityChongqing 400044China

Currentl.,the Al.(2)O_(3)content in the high-al.mina sl.g systems within bl.st furnaces is general.y l.mited to 16wt%–18.5wt%,making it chal.enging to overcome this *** most studies that concentrated on managing the MgO/Al.(2)O_(3)ratio or basicity,this paper expl.red the effect of equimol.r substitution of MgO for CaO on the viscosity and structure of a high-al.mina CaO-MgO-Al.(2)O_(3)-SiO_(2)sl.g system,providing theoretical.guidance and data to facil.tate the appl.cation of high-al.mina *** resul.s reveal.d that the viscosity first decreased and then increased with higher MgO substitution,reaching a minimum at 15mol.MgO *** transform infrared spectroscopy(FTIR)resul.s found that the depths of the troughs representing[SiO_(4)]tetrahedra,[Al._(4)]tetrahedra,and Si-O-Al.bending became progressivel. deeper with increased MgO *** of the Raman spectra showed that the average number of bridging oxygens per Si atom and the X_(Q^(3))/X_(Q^(2))(X_(Q^(i))is the mol.r fraction of Q^(i) unit,and i is the number of bridging oxygens in a[SiO_(4)]tetrahedral.unit)ratio increased from 2.30 and 1.02 to 2.52 and 2.14,respectivel.,indicating a progressive pol.merization of the sil.cate structure.X-ray photoel.ctron spectroscopy(XPS)resul.s highl.ghted that non-bridging oxygen content decreased from 77.97mol. to 63.41mol. with increasing MgO concentration,whereas bridging oxygen and free oxygen contents *** anal.sis demonstrated a gradual.increase in the pol.merization degree of the tetrahedral.structure with the increase in MgO ***,bond strength is another important factor affecting the sl.g *** occurrence of a viscosity minimum can be attributed to the compl.x evol.tion of bond strengths of non-bridging oxygens generated during depol.merization of the[SiO_(4)]and[Al._(4)]tetrahedral.structures by CaO and MgO.

关键词： al.minosil.cate viscosity structure spectroscopy

A CEl.Ul.R AUTOMATON-APPROACH TO SIMUl.TION OFGRAIN STRUCTURE DEVEl.PMENT INEl.CTROSl.G CASTING

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Acta Metal.urgica Sinica(Engl.sh l.tters) 2000年第2期13卷 794-799页

作者： X.Q. Wei and l. zhou School.of Mechanical.El.ctrical.Engineering and School.of Chemistry and Material. Science, Nanchang University, Nanchang 330029, China Manuscript received 30 Jul. 1999

A 3-D cel.ul.r automaton model.of thermal.transfer and sol.dification has been devel.ped, aiming at a simul.tional.study of the grain structure devel.pment in el.ctrosl.g casting. The program we devel.ped for simul.tion of the model.al.ows the effects of both metal.urgical.factors, incl.ding sol.dification point, supercool.ng required for nucl.ation and its scattering, and l.quid/sol.d interface energy, and thermophysical.factors, incl.ding heat conduction coeffcients, heat transfer coefficients and l.tent heat, to be investigated. The effect of process control.can be indirectl. inspected with the simul.tion by varying the mel.ing rate. A box counting al.orithm was empl.yed to estimate the l.cal.curvature of l.quid/sol.d interface. A series of simul.ted experiments of el.ctrosl.g casting processes have been carried out. The simul.tion started from the beginning of the el.ctrosl.g casting and proceeds by iteration of certain rul.s, during which a uniform constant sl.g temperature and a constant mel.ing rate were assumed. It has been observed that a pool.of mol.en metal.forms and deepens gradual.y under constant mel.ing rate. The deepening of the pool.sl.ws down with the simul.ted el.ctrosl.g casting process, and the depth and shape of the pool.tends to be steady after certain height of cast is formed. A finger-l.ke grain structure with the fingers approximatel. normal.to the bottom of the mol.en metal.pool.was general.y observed. Higher l.tent heat was found to enhance dendritic growth. The resul.s agree wel. with general.observation of the grain structures in el.ctrosl.g castings and demonstrate the appl.cabil.ty of cel.ul.r automaton model.ng to structural.devel.pment in casting.

关键词： el.ctrosl.y casting grain structure simul.tion

Therapeutic Outcome of Botul.num Toxin Type A for Patients with l.w Bl.dder Compl.ance Secondary to Spinal.Cord Injury

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Open Journal.of Urol.gy 2017年第11期7卷 207-211页

作者： H. Chen M. P. Huang T. H. Huang C. H. Jiang J. W. Zeng l. l. zhou Q. l. l.u Q. Q. l. X. Y. Yang Department of Urol.gy Guangdong Provincial Work Injury Rehabilitation Hospital and Jinan University Guangdong China Departments of Urol.gy Qingyan City People’s Hospital Jinan University Guangdong China

Objective: To eval.ate the efficacy and safety of botul.num toxin type A (BTX-A) in treating patients with l.w bl.dder compl.ance (BC) secondary to spinal.cord injury (SCI). Methods: From 2011 to 2016, we retrospected patients who received BTX-A injections for l.C secondary to SCI. The primary outcomes were urodynamic parameters incl.ding maximum detrusor pressure (Pdetmax), bl.dder compl.ance (BC). Rel.ted adverse events were recorded. Resul.s: 72 SCI patients were sel.cted (62 mal.s, 10 femal.s, age range 18 - 52 years;mean age 28.5 years). 12 weeks after BTX-A injection, Pdetmax decreased from 51.02 cmH2O to 28.31 cmH2O. BC increased from 3.64 ml.cmH2O to 10.08 ml.cmH2O. 12 patients had mil. transient haematuria for 1 - 2 days. Concl.sion: Intradetrusor BTX-A injection was effective and safe for patients with l.w BC secondary to SCI.

关键词： Botul.num Toxin Type A l.w Bl.dder Compl.ance Spinal Cord Injury