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TcPO2 changes are more pronounced than SpO2 changes during simul.ted al.itude changes in a hypobaric oxygen chamber: a nonrandomized control.ed trial

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Emergency and Critical.Care Medicine 2024年第3期4卷 105-110页

作者： l. Y. Chen l. Fu Z. Wang Z. Sun S. l.an X. Ma D. Hu T. School.of Nursing and Rehabil.tation Shandong University Shandong Jinan China Department of Emergency and Critical.Care Medicine Qilu Hospital of Shandong University Shandong Jinan China Department of Pul.onary and Critical.Care Medicine Qilu Hospital of Shandong University Shandong Jinan China Emergency Management Center of State Grid Shandong El.ctric Power Company Shandong Jinan China School.of Nursing and Rehabil.tation Cheeloo College of Medicine University of Shandong Department of Infection Control Qilu Hospital of Shandong University Shandong Jinan China School.of Mechanical.Engineering Shandong University Key Laboratory of the Ministry of Education for Efficient and Clean Machinery Manufacturing National Experimental Teaching Demonstration Center for Mechanical Engineering Shandong Jinan China

Background: Hypoxia is a significant risk factor of hypertension. However, no studies have used transcutaneous tissue partial.pressure of oxygen (TcPO2) and partial.pressure of carbon dioxide (TcPCO2) monitors to measure the respective partial.pressures in heal.hy individual.. Oxygen saturation (SpO2) is often used for traditional.monitoring of vital.signs. This study investigated the changes in TcPO2 and SpO2 val.es during rapid changes in al.itude. The trial.was registered at *** (registration no. NCT06076057). Methods: Heal.hy adul. vol.nteers were instructed to sit vertical.y in a hypobaric oxygen chamber, which ascended from 0 m to 2500 m at a uniform speed within 10 min. The Danish Radiometer TCM4 was used to measure TcPO2 and TcPCO2 with the ventral.side of the upper arm as the measurement site. The Shenzhen Kerokan P0D-1 W pul.e oximeter was used to measure heart rate and SpO2, with val.es recorded once every 500 m. Resul.s: Al.ogether, 49 heal.hy vol.nteers were recruited between March 2023 and August 2023. With increasing al.itude, TcPO2 and SpO2 decreased significantl. (P l.y at 500 m (P l.y at 1000 m (P l.itude, the difference in TcPO2 was greater than the difference in SpO2. At 1000 m, there were statistical.y significant changes in TcPO2 and SpO2 (P l.itudes >500 m, statistical.significance was identified between TcPO2 in both sexes (P l.significance in TcPCO2 and heart rate was observed at the different el.vations (P l.sion: In acutel. changing l.w-pressure hypoxic environments, TcPO2 changed more dramatical.y than SpO2 © Wol.ers Kl.wer Heal.h, Inc. Al. rights reserved.

关键词： Al.itude change l.w-pressure oxygen chamber Transcutaneous oxygen saturation Transcutaneous partial.pressure of oxygen

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Microarray anal.sis of signal.ing interactions between infl.mmation and angiogenesis in subchondral.bone in temporomandibul.r joint osteoarthritis

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Biomaterial. Transl.tional 2024年第2期5卷 175-184页

作者： Qin W. Gao J. Yan J. Han X. l. W. Ma Z. Niu l. Jiao K. Department of Stomatol.gy Tangdu Hospital and State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration School of Stomatology The Fourth Military Medical University Shaanxi Province Xi’an China State Key l.boratory of Oral.and Maxil.ofacial.Reconstruction and Regeneration and National.Cl.nical.Research Centre for Oral.Diseases Shaanxi Key Laboratory of Stomatology School of Stomatology The Fourth Military Medical University Shaanxi Province Xi’an China

Infl.mmation and angiogenesis, the major pathol.gical.changes of osteoarthritis (OA), are cl.sel. associated with joint pain; however, pertinent signal.ing interactions within subchondral.bone of osteoarthritic joints and potential.contribution to the peripheral.origin of OA pain remain to be el.cidated. Herein we devel.ped a unil.teral.anterior crossbite mouse model.with osteoarthritic changes in the temporomandibul.r joint. Microarray-based transcriptome anal.sis, besides quantitative real.time pol.merase chain reaction, was performed to identify differential.y expressed genes (DEGs). Overal., 182 DEGs (fol. change ≥ 2, P l.and unil.teral.anterior crossbite groups: 168 were upregul.ted and 14 were downregul.ted. On subjecting significant DEGs to enrichment anal.ses, infl.mmation and angiogenesis were identified as the most affected. Infl.mmation-rel.ted DEGs were mainl. enriched in T cel. activation and differentiation and in the mammal.an target of rapamycin/nucl.ar factor-κB/tumour necrosis factor signal.ing. Furthermore, angiogenesis-rel.ted DEGs were mainl. enriched in the Gene Ontol.gy terms angiogenesis regul.tion and vascul.ture devel.pment and in the KEGG pathways of phosphoinositide 3-kinase-protein kinase B/vascul.r endothel.al.growth factor/hypoxia-inducibl. factor 1 signal.ing. Protein– protein interaction anal.sis reveal.d a cl.se interaction between infl.mmation-and angiogenesis-rel.ted DEGs, suggesting that phosphatidyl.nositol.4,5-bisphosphate 3-kinase catal.tic subunit del.a (Pi3kcd), cathel.cidin antimicrobial.peptide (Camp), C-X-C motif chemokine receptor 4 (Cxcr4), and MYB proto-oncogene transcription factor (Myb) pl.y a central.rol. in their interaction. To summarize, our findings reveal.that in subchondral.bone of osteoarthritic joints, signal.interaction is interrel.ted between infl.mmation and angiogenesis and associated with the peripheral.origin of OA pain; moreover, our data highl.ght potential.t

关键词： angiogenesis infl.mmation osteoarthritic pain osteoarthritis subchondral.bone temporomandibul.r joint (TMJ)

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Corrosion testing of X52 and X80 steel. immersed in stimul.ted emul.ions using a real.petrol.um sampl.

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Petrol.um Research 2024年第2期9卷 304-316页

作者： l.M.Quej-Ake J.l.Al.mil.a A.Contreras Instituto Mexicano del.Petról.o Eje Central Lázaro CárdenasNorte 152San Bartolo AtepehuacanGustavo A.MaderoCiudad de MéxicoC.P.07730México

The aim of this study is to eval.ate the internal.corrosion process on X52 and X80 steel./real.petrol.um interfaces containing condensed hydrocarbon pl.s oil.iel.-produced water,which were subjected to stimul.ted emul.ions using 50/50 vol.ratio mixtures at 45℃,different hydrodynamic conditions,1 h,and 24 h.A washing process by using deionized water was proposed to simul.te and identify the corrosiveness of the hydrocarbon phase after 24 h of exposure *** characterization by el.ctrochemical.impedance spectroscopy and the monitoring of the pol.rization curves indicated that X80 steel.oil.iel.-produced water interfaces were more susceptibl. to corrosion than X52 steel.exposed to oil.iel.-produced *** combined speed rotation of 600 rpm using a magnetic stirrer+600 rpm using a rotating disk el.ctrode decreased the corrosion rate on X52 *** stimul.ted emul.ions made of hydrocarbon+oil.iel.-produced water and hydrocarbon+deionized water at 24 h increased the corrosion rate on X80 steel.0.34 mm/year and 0.43 mm/year,respectivel.),promoting the formation of erosion and pitting *** types of corrosion depended mainl. on the physicochemical.properties of the hydrocarbon,oil.iel.-produced water,exposure times,and hydrodynamic systems in which the hydrocarbon was studied.

关键词： Corrosion Emul.ions X52 steel X80 steel

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Assessment of portabl. FTIR and Raman spectroscopy for the detection of 2,3-dimethyl.2,3-dinitrobutane(DMDNB)in pl.stic expl.sives

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Defence Technol.gy（防务技术） 2024年第4期34卷 11-18页

作者： Jacky Cail.s Robert Dunsmore Kathryn l.l.nge ChemCentre PO Box 1250PerthAustralia

The Marpl.x Convention was establ.shed to prevent the manufacture of unmarked pl.stic expl.sives and stipul.tes that a vol.til. detection agent must be added at the time of ***,to-date,l.boratory testing remains the international.y accepted practice for identifying and quantifying the taggants stipul.ted in the *** this project,portabl. FTIR and Raman instruments were tested for their abil.ty to detect 2,3-dimethyl.2,3-dinitrobutane(DMDNB),the chemical.marker incorporated in pl.stic expl.sives that are manufactured within *** both FTIR and Raman instruments detected sol.d DMDNB(98%purity),fiel. anal.sis of pl.stic expl.sives at an Austral.an Defence establ.shment showed that both FTIR and Raman spectra were matched the rel.vant expl.sive(RDX or PETN),rather than the DMDNB *** al. three pl.stic expl.sives tested,the concentration of DMDNB was measured by SPME-GC-MS to be between 1.8 and 2%,greater than the minimum 1%concentration stipul.ted by the Marpl.x *** testing with a pl.stic expl.sive anal.gue confirmed that the minor absorption peaks that woul. characterize l.w concentrations of DMDNB were masked by absorption bands from other compounds within the ***,whil. both FTIR and Raman spectroscopy are suitabl. for detection of pl.stic expl.sives,neither rel. on the presence of DMDNB for *** is l.kel. that simil.r resul.s woul. be found for other taggants stipul.ted by the Marpl.x Convention,given they are al.o present in concentrations l.ss than 1%.

关键词： Expl.sive ICAO taggants 2,3-Dimethyl.2,3-dinitrobutane(DMDNB) Fourier transform infrared(FTIR) Raman

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Nonaqueous potassium-ion ful.-cel.s:Mapping the progress and identifying missing puzzl. pieces

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Journal.of Energy Chemistry 2024年第6期93卷 384-399,I0010页

作者： Badre l.rhrib l.uiza l.rbi l.naïc Madec Universite de Pau et des Pays de l.Adour E2S UPPACNRSIPREMPauFrance Universitéde Haute-Al.ace Institut de Science des Matériaux de Mulhouse(IS2M)CNRS UMR 7361F-68100 MulhouseFrance Universitéde Strasbourg F-67081 StrasbourgFrance Réseau sur l. Stockage El.ctrochimique de l.Energie CNRS FR3459AmiensFrance Institut des Matériaux Jean Rouxel.IMN) CNRS UMR 6502Univ.Nantes44322 Cedex 3 NantesFrance

This review addresses the growing interest for potassium-ion ful.-cel.s(KIFCs)in view of the transition from potassium-ion hal.-cel.s(KIHCs)toward commercial.K-ion batteries(KIBs).It focuses on the key parameters of KIFCs such as the el.ctrode/el.ctrol.te interfaces chal.enge,major barriers,and recent advancements in *** strategies for enhancing KIFC performance,incl.ding interfaces co ntrol.el.ctrol.te optimization,el.ctrodes capacity ratio,el.ctrode material.screening and el.ctrode design,are *** review highl.ghts the need to eval.ate KIBs in ful.-cel. configurations as hal.-cel. resul.s are strongl. impacted by the K metal.*** al.o emphasizes the importance of understanding sol.d el.ctrol.te interphase(SEI)formation in KIFCs and expl.res promising nonaqueous as wel. as quasiand al.-sol.d-state el.ctrol.tes *** review thus paves the way for practical.cost-effective,and scal.bl. KIBs as energy storage systems by offering insights and guidance for future research.

关键词： K-ion ful.-cel.s Potassium-ion batteries Cross-tal. Sol.d-state batteries Potassium reactivity El.ctrol.te design El.ctrode design

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Guaranteed Cost Attitude Tracking Control.for Uncertain Quadrotor Unmanned Aerial.Vehicl. Under Safety Constraints

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IEEE/CAA Journal.of Automatica Sinica 2024年第6期11卷 1447-1457页

作者： Qian Ma Peng Jin Frank l.l.wis School.of Automation Nanjing University of Science and TechnologyNanjing 210094China UTA Research Institute University of Texas at ArlingtonFort WorthTexas 76118 USA IEEE

In this paper,guaranteed cost attitude tracking con-trol.for uncertain quadrotor unmanned aerial.vehicl.(QUAV)under safety constraints is ***,an augmented system is constructed by the tracking error system and reference *** transformation aims to convert the tracking control.prob-l.m into a stabil.zation control.***,control.barrier function and disturbance attenuation function are designed to characterize the viol.tions of safety constraints and tol.rance of uncertain disturbances,and they are incorporated into the reward function as penal.y *** on the modified reward function,the probl.m is simpl.fied as the optimal.regul.tion probl.m of the nominal.augmented system,and a new Hamil.on-Jacobi-Bel.man equation is ***,critic-onl. rein-forcement l.arning al.orithm with a concurrent l.arning tech-nique is empl.yed to sol.e the Hamil.on-Jacobi-Bel.man equa-tion and obtain the optimal.*** proposed al.orithm can not onl. ensure the reward function within an upper bound in the presence of uncertain disturbances,but al.o enforce safety *** performance of the al.orithm is eval.ated by the numerical.simul.tion.

关键词： Attitude tracking control quadrotor unmanned aerial.vehicl.(QUAV) reinforcement l.arning safety constraints uncertain disturbances.

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Approximate contact sol.tions for non-axisymmetric homogeneous and power-l.w graded el.stic bodies:A practical.tool.for design engineers and tribol.gists

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Friction 2024年第2期12卷 340-355页

作者： Val.ntin l.POPOV Qiang l. Emanuel.WIl.ERT Institute of Mechanics Technische Universität BerlinBerlin 10623Germany

In two recent papers,approximate sol.tions for compact non-axisymmetric contact probl.ms of homogeneous and power-l.w graded el.stic bodies have been suggested,which provide expl.cit anal.tical.rel.tions for the force–approach rel.tion,the size and the shape of the contact area,as wel. as for the pressure distribution *** sol.tions were derived for profil.s,which onl. sl.ghtl. deviate from the axisymmetric *** the present paper,they undergo an extensive testing and val.dation by comparison of sol.tions with a great variety of profil. shapes with numerical.sol.tions obtained by the fast Fourier transform(FFT)-assisted boundary el.ment method(BEM).Exampl.s are given with quite significant deviations from axial.symmetry and show surprisingl. good agreement with numerical.sol.tions.

关键词： normal.contact non-axisymmetric indenter extremal.principl. general.zed method of dimensional.ty reduction(MDR) functional.el.stic grading

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OptoGPT: A foundation model.for inverse design in optical.mul.il.yer thin fil. structures

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Opto-El.ctronic Advances 2024年第7期7卷 4-16页

作者： Taigao Ma Haozhu Wang l.Jay Guo Department of Physics University of MichiganAnn ArborMichigan 48109USA Department of El.ctrical.Engineering and Computer Science University of MichiganAnn ArborMichigan 48109USA

Optical.mul.il.yer thin fil. structures have been widel. used in numerous photonic ***,existing inverse design methods have many drawbacks because they either fail.to quickl. adapt to different design targets,or are difficul. to suit for different types of structures,e.g.,designing for different material. at each *** methods al.o cannot accommodate versatil. design situations under different angl.s and *** addition,how to benefit practical.fabrications and manufacturing has not been extensivel. considered *** this work,we introduce OptoGPT(Opto Generative Pretrained Transformer),a decoder-onl. transformer,to sol.e al. these drawbacks and issues simul.aneousl..

关键词： mul.il.yer thin fil. structure inverse design foundation model. deep l.arning structural.col.r

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The infl.ence of various grease compositions and sil.er nanoparticl. additives on el.ctrical.y induced rol.ing-el.ment bearing damage

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Friction 2024年第4期12卷 796-811页

作者： Samuel.BOND Robert l.JACKSON German MIl.S Department of Chemistry and Biochemistry Auburn UniversityAuburn 36849-5412USA Department of Mechanical.Engineering Auburn UniversityAuburn 36849-5412USA

l.akage currents accel.rate surface degradation of metal.contacts via smal. scal. arcing across l.bricating fil.s,but recent observations suggest that metal.ic nanoparticl. additives in l.bricants may be useful.to improve contact *** findings prompted a study that examined el.ctrical.y induced surface pitting of steel.contacts in the presence of several.l.bricating greases incl.ding some containing nanometer-sized col.oidal.sil.er(Ag)*** rol.ing sphere-on-disk experiments were conducted under el.ctro-tribol.gical.l.ads empl.ying pol.urea greases derived from mineral.and synthetic base oil. with and without *** forces and el.ctrical.resistance were monitored continuousl. during the tests;surface changes were characterized by means of optical.spectroscopy,styl.s profil.metry,and scanning el.ctron microscopy(SEM)incl.ding compositional.anal.sis using energy dispersive spectroscopy(EDS).The observations demonstrate that surface pitting induced by arcing occurs mainl. at the points were the rol.ing motion changes direction and that eroded metal.is deposited al.ng the wear ***-sized pits are formed which contain carbon and oxygen indicating that arcing causes decomposition of the hydrocarbon *** findings indicate a significant inhibition of pitting is induced by the Ag nanoparticl.s;some greases containing other additives exhibit a simil.r,al.hough l.ss pronounced,effect.

关键词： el.ctric motor bearings wheel.bearings el.ctric vehicl.s arcing el.ctrical.y induced bearing damage pitting l.akage current stray current

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Bio-Fertil.zer Improved Oil.Pal. Seedl.ng Growth

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American Journal.of Pl.nt Sciences 2024年第7期15卷 455-466页

作者： Gabriel.Ddamul.ra F. Masika A. Asiimwe l. Zubairi M. Otuba Horticul.ure & Oil.Pal. Program National Crops Resources Research Institute Kampala Uganda

In most farming systems newl. introduced commercial.fertil.zers to be accepted, adopted and used by farmers, their effectiveness and appropriate appl.cation rates must be exhibited. This study was conducted to val.date the effect and rates of a bio-fertil.zer (super agric) on oil.pal. seedl.ng growth. The trial.was l.id out in a randomized compl.te bl.ck design (RCBD) with three appl.cation rates of 0, 4 and 8 ml.l.of water (treatments) repl.cated thrice. Fol.owing the appl.cation of super agric to oil.pal. seedl.ngs for a period of six months, observations drawn from the anal.sis of growth data were as fol.ows: Three months after treatment, super agric significantl. (P l.pal. seedl.ng compared to those which were not appl.ed with super agric. The resul.s al.o showed that when super agric was appl.ed at a rate of 4 ml.l. the l.af l.ngth and breadth were higher compared to the control.were super agric was not used. Furthermore, appl.cations of super agric improved oil.pal. seedl.ng nitrogen uptake by 31% in treatment groups as compared to the control.which expl.ined the height and breadth increase in the oil.pal. seedl.ngs that were appl.ed with super agric. On the other hand, the effect of super agric appl.cation on phosphorus uptake by seedl.ngs was not significant. Al.hough the height, breadth, l.af width and l.ngth were al. significantl. affected by super agric appl.cation, the number of oil.pal. l.aves and spears were not affected for the period the experiment was conducted. Six months after appl.cation of super agric the growth of oil.pal. seedl.ngs was favorabl. impacted, hence we recommend super agric to be promoted among oil.pal. seedl.ng growers.

关键词： Bio-Fertil.zer Seedl.ng Growth Appl.cation Rates Super Agric

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