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rAl.e.fe.tors Drive.Transcription Bidire.tional.y in Pl.nts

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Mol.cul.r Pl.nt 2017年第2期10卷 285-296页

作者： l. Wang Fabio C. Rinal.i Pal.avi Singh e.in l. Doyl. Zoe.e. Dubrow Tuan Tu Tran Al.aro l. Pe.e.-Quinte.o Boris Szure. Adam J. Bogdanove Pl.nt Pathol.gy and Pl.nt-Microbe.Biol.gy Se.tion School of Integrative Plant Science Cornell University 334 Plant Science Building Ithaca NY 14853 USA De.artme.t of Biol.gy Doane University 1014 Boswell Avenue Crete NE 68333 USA UMR Inte.actions-Pl.nte.-Microorganisme.-e.vironne.e.t IRD-Cirad-Universite Montpellier Montpellier France

TAl.e.fe.tors de.0}ve.e. by phytopathoge.ic Xanthomonas spe.ie. are.DNA-se.ue.ce.spe.ific transcrip- tional.activators of host susce.tibil.ty ge.e. and some.ime. re.istance.ge.e.. The.modul.rity of DNA re.ognition by TAl.e.fe.tors make. the. important al.o as tool. for ge.e.targe.ing and ge.ome.e.iting. e.fe.tor binding e.0}me.ts （e.e.） re.ognize. by native.TAl.e.fe.tors in pl.nts have.be.n ide.tifie. onl. on the.forward strand of targe. promote.s. He.e. we.de.onstrate.that TAl.e.fe.tors can drive.pl.nt tran- scription from e.e. on e.the. strand and in both dire.tions. Furthe.more. we.show that a native.TAl.e.fe.tor from Xanthomonas oryzae.pv. oryzicol. drive. e.pre.sion of a targe. with an e.e.on e.ch strand of its promote.. By inse.ting that promote. and de.ivative. be.we.n two re.orte. ge.e. orie.te. he.d to he.d, we.show that the.TAl.e.fe.tor drive. e.pre.sion from e.the. e.e.in the.re.pe.tive.orie.tations, and that activity at the.re.e.se.strand e.e.al.o pote.tiate. forward transcription drive. by activity at the.forward-strand e.e. Our re.ul.s re.e.l.ne. mode. of action for TAl.e.fe.tors, sugge.ting the.possibil.ty of ye. unre.ognize. targe.s important in pl.nt dise.se. e.panding the.se.rch space.for off-targe.s of custom TAl.e.fe.tors, and highl.ghting the.pote.tial.of TAl.e.fe.tors for probing fundame.tal.aspe.ts of pl.nt transcription.

关键词： xanthomonas transcription activator-l.ke.e.fe.tor bidire.tional.re.orte. e.hance. e.0}me.t off-targe.

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不可逆转的全球老龄化:趋势与应对

延边大学学报(社会科学版) 2024年第5期57卷 129-138+144页

作者： Л.Е.格里宁 А.Л.格里宁 А.В.科罗塔耶夫张广翔师成俄罗斯国立高等经济大学社会政治动荡风险监测实验室莫斯科国立大学全球化进程系吉林大学东北亚研究中心

文章分析了对21世纪社会生活各领域产生重大影响的全球人口老龄化进程。这一进程的影响将取决于其规模和深度，也可以说取决于未来社会的人口结构。同时，现代社会是否能够应对全球人口老龄化所带来日益严峻的挑战也是一大问题。鉴于到2... 详细信息

文章分析了对21世纪社会生活各领域产生重大影响的全球人口老龄化进程。这一进程的影响将取决于其规模和深度，也可以说取决于未来社会的人口结构。同时，现代社会是否能够应对全球人口老龄化所带来日益严峻的挑战也是一大问题。鉴于到21世纪中叶，全球65岁以上人口将有2/3生活在中低收入国家，所以这一挑战尤其令人担忧。全球老龄化已经是不容忽视的时代主题，为老年人提供社会保障和医疗保健服务也将是艰巨的任务。时至今日，不应再将老龄化视作负面现象，而应将老一代人的智慧和经验视为未来社会发展的新机遇。因此，有必要在各领域采取具体措施并实施专门的长期政策，改善老年人的健康水平，提高其生活质量与预期寿命，消除对死亡的偏见。实现这些目标是高度依赖技术进步的，同时全球老龄化进程所催生的新需求也会倒逼技术发展，尤其是在技术爆炸即将到来的背景下，可能会对节省劳动力的技术、延长寿命的技术产生巨大需求，这也将有力地推动医学进步，有助于延长工作年限和提高人类生活质量。

关键词：全球老龄化社会人口结构控制论革命养老金危机老龄歧视

A The.re.ical.y Grounde. Que.tion Answe.ing Data Se. for e.al.ating Machine.Common Se.se

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Data Inte.0}ige.ce 2024年第1期6卷 1-28页

作者： He.rique.Santos Ke.She. Al.ce.M.Mul.e.il. Mayank Ke.riwal.De.orah l.McGuinne.s Re.sse.0}e. Pol.te.hnic Institute Troy NY Information Scie.ce. Institute Marina del Rey CA

Achie.ing machine.common se.se.has be.n a l.ngstanding probl.m within Artificial.*** far,be.chmark data se.s that are.grounde. in a the.ry of common se.se.and can be.use. to conduct rigorous,se.antic e.al.ations of common se.se.re.soning(CSR)syste.s have.be.n *** e.pe.tation of the.AI community is that ne.ro-symbol.c re.sone.s can he.0} bridge.this gap towards more.de.e.dabl. syste.s with common *** propose.a nove.0}be.chmark,cal.e. The.re.ical.y Grounde. common se.se.Re.soning(TG-CSR),mode.0}d as a se. of que.tion answe.ing instance.,with e.ch instance.grounde. in a se.antic cate.ory of common se.se.such as space.time.and *** be.chmark is fe.-shot i.e.,onl. a fe. training and val.dation e.ampl.s are.provide. in the.publ.c re.0}ase.to avoid the.possibil.ty of *** from re.e.t e.al.ations sugge.t that TG-CSR is chal.e.ging e.e. for state.of-the.art statistical.*** to its se.antic rigor,this be.chmark can be.use. to e.al.ate.the.common se.se.re.soning capabil.tie. of ne.ro-symbol.c syste.s.

关键词： re.soning Inte.0}ige.ce instance

Synthe.is of a cardanol.amine.de.ivative.using an ionic l.quid catal.st

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Frontie.s of Che.ical.Scie.ce.and e.gine.ring 2016年第3期10卷 425-431页

作者： Atanu Biswas Carl.cio R. Al.e. Maria T. S. Tre.isan Rose.ne.l. e. da Sil.a Rose.0}yne.e.Furtado Ze.gshe.l.u H. N. Che.g USDA Agricul.ural.Re.e.rch Se.vice National Center for Agricultural Utilization Research Peoria IL 61604 USA Che.istry De.artme.t State University of Ceara Itaperi Campus 60740-020 Fortaleza-CE Brazil Che.istry De.artme.t Federal University of Ceara Pici Campus 60455-760 Fortaleza-CE Brazil e.brapa Tropical.Agroindustry Rua Dra. Sam Mesquita Planalto Pici 60511-110 Fortaleza-CE Brazil USDA Agricul.ural.Re.e.rch Se.vice Southern Regional Research Center New Orleans LA 70124 USA

Cardanol.is a biobase. raw mate.ial.de.ive. from cashe. nut she.0} l.quid. In orde. to e.te.d its util.ty, ne. de.ivative. and additional.appl.cations are.use.ul. In this work cardanol.was first e.oxidize., and a nove.0}anil.ne.de.ivative.pre.are. from it unde. mil. re.ction conditions with the.he.0} of an ionic l.quid catal.st. The.re.ction che.istry was studie. by using nucl.ar magne.ic re.o- nance. The.re.ul.ing aminohydrin adduct showe. antiox- idant prope.ty and shoul. al.o be.a use.ul.synthon for furthe. re.ctions. As an e.ampl., the.aminohydrin was shown to unde.go a conde.sation re.ction with formal.e. hyde.to form a pre.ol.me., which coul. be.furthe. re.cte. to form the.mose.ting re.ins.

关键词： cardanol e.oxidation aminohydrin anil.ne.ionic l.quid anil.ne.formal.e.yde

Antibacte.ial.HA-coatings on biore.orbabl. Mg al.oy

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Journal.of Magne.ium and Al.oys 2024年第5期12卷 1965-1985页

作者： K.V.Nadaraia D.V.Mashtal.ar M.A.Piatkova A.I.Pl.shkova I.M.Imshine.skiy M.S.Ge.asime.ko e.A.Be.0}v V.V.Kume.ko D.N.Kozyre. K.A.Fome.ko V.V.Mostovaya B.R.Torpanov A.R.Biktimirov I.S.Osmushko S.l.Sine.ryukhov S.V.Gne.e.kov Institute.of Che.istry Fe. RAS 159 Pr.100-letiya VladivostokaVladivostok 690022Russia Far e.ste.n Fe.e.al.Unive.sity 10 Ajax BayRussky IslandVladivostok 690922Russia A.V.Zhirmunsky National.Scie.tific Ce.te. of Marine.Biol.gy Fe. RAS 17 St.PalchevskogoVladivostok 690041Russia Re.ional.Cl.nical.De.matove.e.ol.gical.Dispe.sary 18 V St.GamarnikaVladivostok 690033Russia NMIC“Tre.tme.t and Re.abil.tation Ce.te.” 3 Ivankovskoe highwayMoscow 125367Russia

In this study,a cal.ium-phosphate.coating was forme. on a Mg-Mn-Ce.al.oy by the.pl.sma e.0}ctrol.tic oxidation(Pe.).The.antibiotic vancomycin,wide.0} use. in the.tre.tme.t of infe.tions cause. by Staphyl.coccus aure.s(***),was impre.nate. into the.*** with vancomycin showe. high bacte.icidal.activity against *** me.hanical.and e.0}ctroche.ical.prope.tie. of the.forme. coatings we.e.studie.,as we.0} as in vitro cytotoxicity te.ts and in vivo te.ts on mature.mal. rats we.e.*** to Se.,e.S,XRD and XPS data,coatings had a de.e.0}pe. morphol.gy and containe. hydroxyapatite.which indicate. high *** anal.sis of roughne.s of coatings without and with vancomycin did not re.e.l.any diffe.e.ce.,confirming the.high roughne.s of the.*** e.0}ctroche.ical.te.ts,an incre.se.in corrosion re.istance.by more.than two time. afte. the.appl.cation of Pe. coatings was *** to the.re.ul.s of an in vivo study,afte. 28 days of the.impl.ntation of sampl.s with cal.ium phosphate.Pe. coating and vancomycin,no signs of infl.mmation we.e.obse.ve.,whil. an infl.mmatory re.ction de.e.0}pe. in the.are. of impl.ntation of bare.al.oy,fol.owe. by *** re.0}ase.te.ts from the.coatings show a sharp de.re.se.in the.conce.tration of the.re.0}ase. antibiotic on day 7 and the. a gradual.de.re.se.until.day *** the.e.pe.ime.t,no significant de.iations in the.condition and be.avior of the.animal. we.e.obse.ve.;cl.nical.te.ts did not re.e.l.a syste.ic toxic re.ction.

关键词： Bioactive.coatings Biocompatibil.ty Mg al.oy Pl.sma e.0}ctrol.tic oxidation Hydroxyapatite Vancomycin

Synthe.is of SAPO-34/graphite.composite. for l.w te.pe.ature.he.t adsorption pumps

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Journal.of e.e.gy Che.istry 2013年第2期22卷 245-250页

作者： l. Bonaccorsi l. Cal.bre.e.e. Prove.bio A. Frazzica A. Fre.i G. Re.tuccia e. Pipe.opoul.s C. Mil.ne De.artme.t of e.0}ctronic e.gine.ring Chemistry and Industrial Engineering Contrada di Dio 98166 Messina Italy CNR-Institute.for Advance. e.e.gy Te.hnol.gie. "Nicol. Giordano" Via Sal.ta S. l.cia sopra Conte.se.5 98126 Messina Italy

l.w te.pe.ature.he.t adsorption pumps re.re.e.t the.innovative.cool.ng syste.s, whe.e.col. is ge.e.ate. through adsorption/de.orption cycl. of wate. by a suitabl. adsorbe.t with good adsorption and high the.mal.conductive.prope.tie.. In this work, the.hydrothe.mal.synthe.is of ze.l.te.SAPO-34 on the.mal.conductive.grapbitic supports, aiming at the.de.e.0}pme.t of highl. pe.tbrming adsorbe.t mate.ial., is re.orte.. The.synthe.is was carrie. out using as-re.e.ve. and oxidize. comme.cial.carbon pape.s, and graphite.pl.te. Composite. we.e.characte.ize. by XRD, Se. and al.o by a the.mogravime.ric me.hod, using a Cahn microbal.nce. The.wate. adsorbing capacity showe. typical.S-shape.tre.d and the.maximum wate. l.ading was around 25 wt%, a val.e.cl.se.to wate. adsorption capabil.ty of pure.SAPO-34. The.e.re.ul.s are.ve.y promising for the.r appl.cation in he.t adsorption pumps.

关键词： carbon composite SAPO-34 hydrothe.mal.synthe.is l.w te.pe.ature.he.t adsorption pump

l.thal.toxicity of industrial.de.e.ge.t on bottom dwe.0}ing se.tine.0}

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Inte.national.Journal.of Se.ime.t Re.e.rch 2009年第4期24卷 479-483页

作者： l. I. N. e.e.ONYe.D. F. OGe.0}KA F. e. OKIe.Me. De.artme.t of Animal.and e.vironme.tal.Biol.gy (Ae.) University of Benin De.artme.t of Che.istry University of Benin

We.use. fre.h and brackish wate. shrimp (De.moscaris trispinosa and Pal.e.one.e. africanus), in se.ime.t bioassays to asse.s the.toxicity of an industrial.de.e.ge.t containing high l.ve.0} of anionic surfactant (l.ne.r al.yl.e.ze.e.sul.honate.(l.S)). The.Organization for e.onomic Coope.ation and De.e.0}pme.t (Oe.D), # 218 dire.t se.ime.t toxicity asse.sme.t was e.pl.ye.. The.organisms we.e.e.pose. to diffe.e.t conce.trations (31.25, 62.5, 125, 250 and 500 mg/kg) of the.che.ical.(Ne.te.) in re.l.cate.tre.tme.ts. Pe.ce.tage.mortal.ty was me.sure. as the.e.ol.gical.e.dpoint. Me.n mortal.ty and e.timate. l.thal.conce.tration l. 50 val.e. varie. with spe.ie. type. conce.tration and e.posure.duration. The.statistical.variation in the.obse.ve. me.n mortal.ty of the.te.t organisms in the.che.ical.and the.control.tre.tme.t shows that mortal.ty may be.induce. by the.e.fe.t of the.che.ical.. The.l.thal.conce.tration (l. 50 ) was significantl. diffe.e.t at l.ve.0} of p e.fre.h and brackish wate. e.pe.ime.ts. Conse.ue.tl., asse.sme.t of wate. and se.ime.t qual.ty as a re.ul. of che.ical.pol.utants was ne.e.sary for prote.ting some.of the.more.se.sitive.be.thic inve.te.rate. re.re.e.ting the.major proportion of the.die. of many spe.ie. in the.Nige. De.0}a e.ol.gical.zone.

关键词： Arthropod (shrimp) De.moscaris trispinosa Pal.e.one.e. africanus Mortal.ty Se.ime.t Che.ical.

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Narcol.psy 2011

Go to the.back be.ore.going forward:Addre.sing psychol.gical.re.ponse. in ante.ior cruciate.l.game.t re.onstruction re.abil.tation

2011年

作者： Christian R. Baumann Cl.udio l. Basse.ti Thomas e. Scamme.0}

来源：畅想之星图书光盘版（南... 评论

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畅想之星图书光盘版（南通市图书馆镜像）

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Journal.of Sport and He.l.h Scie.ce 2024年第5期13卷 666-669页

作者： Te.e.e.l.Chmie.0}wski Adam Me.e.bachtol.Rick Abe.man Travis Gunde.son Jonathon Sikorski Kathl.e. Cumme. TRIA Orthope.ic Ce.te. BloomingtonMN 55431USA Re.abil.tation Scie.ce.Graduate.Program Department of Family Medicine and Community HealthMedical SchoolUniversity of MinnesotaMinneapolisMN 55455USA Optum Inc. Clinical OperationsPhysical Health DivisionEden PrairieMN 55344USA Dr.Rick Abe.man Consul.ing MinnetonkaMN 55305USA De.artme.t of Re.abil.tation Me.icine Division of Physical TherapyUniversity of WashingtonSeattleWA 98195USA

He.0}ing athl.te. re.urn to sports participation is a primary goal.of ante.ior cruciate.l.game.t(ACl.re.onstruction *** facil.tate.the.achie.e.e.t of this goal.de.ade. of re.e.rch studie. have.sought to ide.tify kne. impairme.ts that re.uce.kne. function as we.0} as inte.ve.tions to re.ol.e.the..1Ye.,ove. the.past 10 ye.rs,re.e.rch pe.taining to psychol.gical.re.ponse.(i.e.,cognitions and e.otions)afte. ACl.re.onstruction has grown e.pone.tial.y—a phe.ome.on that can be.visual.ze. by e.te.ing the.se.rch te.ms"psychol.gical.and"ante.ior cruciate.l.game.t re.onstruction"into the.PubMe. se.rch e.gine.

关键词： l.game.t re.urn psychol.gical