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Photonics Research 2021年第9期9卷 1784-1795页

作者： TAE-WOO LEE DOHONG KIM JUN hee HAN SOMIN LEE HOSEUNG LEE SEUNGYEOP CHOI kyung CHEOL CHOI School of Electrical Engineering Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Republic of Korea

It is a persistent problem in organic light-emitting diode(OLED)display devices that the efficiency of blue-light source materials is lower than that of green-or red-light source *** address this problem,numerous studies have investigated blue-light-emitting ***,ensuring the reliability of the blue-light-emitting materials has been difficult in most *** this study,electrodes using asymmetric dielectric/metal/dielectric structures with plasmonic quasi-bandgap characteristics were developed to achieve a highly efficient blue fluorescent *** electrodes were applied in a microcavity OLED and a transparent *** the developed electrode in fabricated OLED devices not only maximized the cavity resonance effect and transparency,but also preserved the advantage of the work function of the metal in terms of electrical properties,with high device *** approach also minimized losses caused by surface plasmon polaritons,which is a blind spot in the optical aspect of metal electrodes,resulting in improved light extraction efficiency.

关键词： light blue surface

Injection molding of micro patterned PMMA plate

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Transactions of Nonferrous Metals Society of China 2011年第A1期21卷 148-152页

作者： Yeong-Eun yoo Tae-Hoon KIM Tae-Jin JE Doo-Sun CHOI Chang-Wan KIM Sun-kyung KIM Department of Nanomanufacturing Technology KIMM 171 Jang-dong Yusung-gu Daejeon 305-343 Korea Department of Product Design and Manufacturing Seoul National University of Technology

A plastic plate with surface micro features was injection molded to investigate the effect of pressure rise of melt on the replication of the micro structures. Prism pattern, which is used in many optical applications, was selected as a model pattern. The prism pattern is 50 μm in pitch and 108° in the vertical angle. The overall size of the plate was 335 mm×213 mm and the thickness of the plate varied linearly from 2.6 mm to 0.7 mm. The prism pattern was firstly machined on the nickel plated core block using micro diamond tool and this machined pattern core was installed in a mold for injection molding of prism patterned plate. Polymethyl methacrylate (PMMA) was used as a molding material. The pressure and temperature of the melt in the cavity were measured at different positions in the cavity and the replication of the pattern was also measured at the same positions. The results show that the pressure or temperature profile through the process depends on the shape and the size of the plate. The replication is affected by the temperature and pressure profiles at the early stage of filling, which is right after the melt reaches the position to be measured.

关键词： PMMA 注塑成型塑料板图案聚甲基丙烯酸甲酯压力上升加工模式位置测量

Effect of gadolinium incorporation on optical characteristics of YNbO_4:Eu^(3+) phosphors for lamp applications

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Journal of Rare Earths 2012年第3期30卷 205-209页

作者： Sung Hwan Choi G. Anoop Dong Wook Suh kyung Pil Kim Hyun Ju Lee Jae Soo yoo Display Materials Laboratory School of Chemical Engineering and Materials Science Chung-Ang University

Eu3＋-doped （Y,Gd）NbO4 phosphor was synthesized by solid-state reaction for possible application in cold cathode fluorescent lamps. A broad absorption band with peak maximum at 272 nm was observed which was due to the charge transfer between Eu3＋ ions and neighboring oxygen anions. A deep red emission at the peak wavelength of 612 nm was observed which could be attributed to the 5D0→7F2 transition in Eu3＋ ions. The highest luminance for Y1-x-yGdyNbO4：Eux3＋ under 254 nm excitation was achieved at Eu3＋ concentration of 18 mol.% （x=0.18） and Gd3＋ concentration of 8.2 mol.% （y=0.082）. The luminance of Y0.738Gd0.082NbO4：Eu3＋0.18 was higher than that of a typical commercial phosphor Y2O3：Eu3＋ and the CIE chromaticity coordinate was （0.6490, 0.3506）, which was deeper than that of Y2O3：Eu3＋. The particle size of the synthesized phosphors was controlled by the NaCl flux and particle size as high as 8 μm with uniform size distribution of particles was obtained.

关键词： YNbO4:Eu oxide phosphors rare earths

Association between the early high level of serum tacrolimus and recurrence of hepatocellular carcinoma in ABO-incompatible liver transplantation

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World Journal of Gastrointestinal Surgery 2023年第12期15卷 2727-2738页

作者： Ji Won Han Jong Young Choi Eun Sun Jung Ji Hoon Kim hee Sun Cho Jae-Sung yoo Pil Soo Sung Jeong Won Jang Seung Kew yoon Ho Joong Choi Young Kyoung You Department of Internal Medicine The Catholic University of KoreaSeoul 06591South Korea The Catholic University Liver Research Center College of MedicineThe Catholic University of KoreaSeoul 06591South Korea Department of Hospital Pathology The Catholic University of KoreaSeoul 06591South Korea Department of Surgery The Catholic University of KoreaSeoul 06591South Korea

BACKGROUND Clinical factors predicting graft survival(GS)after ABO-incompatible(ABOi)liver transplantation(LT),and differences between recipients with and without hepatocellular carcinoma(HCC)are *** To analyze the impact of serial serum tacrolimus trough concentration in recipients with or without(HCC)in ABOi living-donor liver transplantation(LDLT).METHODS We analyzed a historical cohort of 89 recipients who underwent ABOi LDLT,including 47 patients with *** The 1-,3-,5-,and 10-year GS rates were 85.9%,73.3%,71.4%,and 71.4%,respectively,and there were no significant differences between HCC and non-HCC *** multivariate Coxregression analyses,tacrolimus trough concentrations below 5.4 ng/mL at 24 wk post-LT,in addition to the antibody-mediated rejection(AMR)were associated with poor-graft *** HCC patients,AMR[hazard ratio(HR)=63.20,P7.3 ng/mL were significant predictive factors for HCC *** propensity score matching,patients with high tacrolimus concentrations at 4 wk had significantly poor recurrence-free *** Elevated tacrolimus levels at 4 wk after ABOi LDLT have been found to correlate with HCC ***,careful monitoring and control of tacrolimus levels are imperative in ABOi LT recipients with HCC.

关键词： ABO-incompatible Liver transplantation Tacrolimus Hepatocellular carcinoma

A potato late blight resistance gene protects against multiple Phytophthora species by recognizing a broadly conserved RXLR-WY effector

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Molecular Plant 2022年第9期15卷 1457-1469页

作者： Xiao Lin Andrea Olave-Achury Robert Heal Marina Pais Kamil Witek hee-kyung Ahn He Zhao Shivani Bhanvadia Hari S.Karki Tianqiao Song Chih-hang Wu Hiroaki Adachi Sophien Kamoun Vivianne G.A.A.Vleeshouwers Jonathan D.G.Jones The Sainsbury Laboratory University of East AngliaNorwich Research ParkNR47UH NorwichUK Wageningen UR Plant Breeding Wageningen University and ResearchDroevendaalsesteeg 16708 PB WageningenThe Netherlands Present address:Institute of Plant Protection Jiangsu Academy of Agricultural SciencesNanjing 210014P.R.China Present address:Institute of Plant and Microbial Biology Academia SinicaTaipei 11529 Taiwan Present address:Laboratory of Crop Evolution Graduate School of AgricultureKyoto UniversityMozumeMukoKyoto 617-0001Japan Present address:Lipman Family Farms 21106 Six Ls Farm RdEsteroFloridaUnited States

Species of the genus Phytophthora,the plant killer,cause disease and reduce yields in many crop *** many Resistance to Phytophthora infestans(Rpi)genes effective against potato late blight have been cloned,few have been cloned against other Phytophthora *** Rpi genes encode nucleotide-binding domain,leucine-rich repeat-containing(NLR)immune receptor proteins that recognize RXLR(Arg-X-Leu-Arg)***,whether NLR proteins can recognize RXLR effectors from multiple Phytophthora species has rarely been ***,we identified a new RXLR-WY effector AVRamr3 from *** that is recognized by Rpi-amr3 from a wild Solanaceae species Solanum ***-amr3 associates with AVRamr3 in ***3 is broadly conserved in many different Phytophthora species,and the recognition of AVRamr3 homologs by Rpi-amr3 activates resistance against multiple Phytophthora pathogens,including the tobacco black shank disease and cacao black pod disease pathogens *** and ***-amr3 is thus the first characterized resistance gene that acts against *** or *** findings suggest a novel path to redeploy known R genes against different important plant pathogens.

关键词： Rpi-amr3 AVRamr3 potato late blight Phytophthora disease RXLR-WY effector Solanum americanum

Speed vernalization to accelerate generation advance in winter cereal crops

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Molecular Plant 2022年第8期15卷 1300-1309页

作者： Jin-kyung Cha Kathryn O'Connor Samir Alahmad Jong-hee Lee Eric Dinglasan Hyeonjin Park So-Myeong Lee Dominique Hirsz Soon-Wook Kwon Youngho Kwon Kyeong-Min Kim Jong-Min Ko Lee T.Hickey Dongjin Shin Laura E.Dixon National Institute of Crop Science RDAMiryang 50424Korea School of Biology Faculty of Biological SciencesUniversity of LeedsLeeds LS29JTUK Queensland Alliance for Agriculture and Food Innovation The University of QueenslandSt.LuciaQLDAustralia Department of Plant Bioscience Pusan National UniversityMiryang 60463Korea

There are many challenges facing the development of high-yielding,nutritious crops for future *** limiting factor is generation time,which prolongs research and plant breeding *** advances in speed breeding protocols have dramatically reduced generation time for many short-day and long-day species by optimizing lightand temperature conditions during plant ***,winter crops with a vernalization requirement stillrequire upto 6-10weeks in low-temperature conditions before thetransition to ***,we tested a suite of environmental conditions and protocols to investigate whether the vernalization process can be *** identified a vernalization method consisting of exposing seeds at the soil surface to an extended photoperiod of 22 h day:2 h night at 10°C with transfer to speed breeding conditions that dramatically reduces generation time in both winter wheat(Triticum aestivum)and winter barley(Hordeum vulgare).Implementation of the speedvernalization protocolfollowed byspeedbreedingallowed the completion ofuptofivegenerations per yearforwinter wheat or barley,whereas only two generations can be typically completed under standard vernalization and plant growth *** speed vernalization protocol developed in this study has great potential to accelerate biological research and breeding outcomes for winter crops.

关键词： speed breeding photoperiod temperature wheat barley breeding

Turbulent vortex trains in narrow square arrayed rod bundles of a dual-cooled nuclear reactor

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Science China(Technological Sciences) 2013年第9期56卷 2143-2149页

作者： KIM Taehwan KIM kyung Min BAE Ji-Yeul SHIN Chang Hwan IN Wang-Kee CHO Hyung hee School of Mechanical Engineering Yonsei University Korea Atomic Energy Research Institute

The dual-cooled nuclear reactor is currently considered for improving the designs of current/future nuclear reactors. Investigation of the thermal-hydraulic characteristics of the nuclear reactor via experiments is essential for commercializing the dual-cooled nuclear reactor. In this paper, the turbulent flow in square arrayed six-rod bundles in the form of magnified copies of the dual-cooled and current OPR-1000 nuclear reactor is experimentally investigated by means of hot-wire anemometry and smoke-wire generation methods. Vortex trains which do not exist in an ordinary reactor subchannel are presented in the subchannel of the dual-cooled reactor. The vortices are induced by a span-wise velocity gradient. This flow pulsation phenomenon increases the inter-channel mixing of the subchannel. To understand the periodic feature of the pulsation, axial/cross velocities are measured and the periodic characteristic frequencies are obtained by a Fast Fourier Transform (FFT) analysis. The peak frequency that represents the quasi-periodic pulsation of the flow is increased with an increase in the axial velocity while the wavelength of the pulsation remains constant within a tested range of the Reynolds number (9000 51000). The vortex trains are highly synchronized with each other, as confirmed by means of visualization.

关键词：核反应堆旋涡列车棒束快速傅立叶变换脉动现象冷却阵列

COVID-19-activated SREBP2 disturbs cholesterol biosynthesis and leads to cytokine storm

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Signal Transduction and Targeted Therapy 2020年第1期5卷 910-920页

作者： Wonhwa Lee June Hong Ahn hee Ho Park Hong Nam Kim Hyelim Kim Youngbum yoo Hyosoo Shin kyung Soo Hong Jong Geol Jang Chun Gwon Park Eun Young Choi Jong-Sup Bae Young-Kyo Seo Aging Research Center Korea Research Institute of Bioscience and BiotechnologyDaejeon 34141Republic of Korea Division of Pulmonology and Allergy Department of Internal MedicineCollege of MedicineYeungnam University and Regional Center for Respiratory DiseasesYeungnam University Medical CenterDaegu 42415Republic of Korea Department of Biotechnology and Bioengineering Kangwon National UniversityChuncheonGangwon-do 24341Republic of Korea Center for BioMicrosystems Brain Science InstituteKorea Institute of Science and Technology(KIST)Seoul 02792Republic of Korea Division of Bio-Medical Science and Technology KIST SchoolKorea University of Science and TechnologySeoul 02792Republic of Korea College of Pharmacy Chungnam National UniversityDaejeon 34134Republic of Korea Department of Biomedical Engineering SKKU Institute for ConvergenceSungkyunkwan University(SKKU)SuwonRepublic of Korea Biomedical Institute for Convergence at SKKU(BICS) Sungkyunkwan University2066 Seobu-roJangan-guSuwon 16419Republic of Korea College of Pharmacy CMRIResearch Institute of Pharmaceutical SciencesBK21 Plus KNU Multi-Omics based Creative Drug Research TeamKyungpook National UniversityDaegu 41566Republic of Korea

Sterol regulatory element binding protein-2(SREBP-2)is activated by cytokines or pathogen,such as virus or bacteria,but its association with diminished cholesterol levels in COVID-19 patients is ***,we evaluated SREBP-2 activation in peripheral blood mononuclear cells of COVID-19 patients and verified the function of SREBP-2 in ***,we report the first observation of SREBP-2 C-terminal fragment in COVID-19 patients’blood and propose SREBP-2 C-terminal fragment as an indicator for determining *** confirmed that SREBP-2-induced cholesterol biosynthesis was suppressed by Sestrin-1 and PCSK9 expression,while the SREBP-2-induced inflammatory responses was upregulated in COVID-19 ICU *** an infectious disease mouse model,inhibitors of SREBP-2 and NF-κB suppressed cytokine storms caused by viral infection and prevented pulmonary *** results collectively suggest that SREBP-2 can serve as an indicator for severity diagnosis and therapeutic target for preventing cytokine storm and lung damage in severe COVID-19 patients.

关键词： cytokine diagnosis damage

Structural Analysis of FRIGIDA Flowering-Time Regulator

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Molecular Plant 2016年第4期9卷 618-620页

作者： kyung-gi Hyun Jee Eun Oh Jihye Park yoo-Sun Noh Ji-Joon Song Department of Biological Sciences KAIST Institute of the BioCentury KAIST Daejeon 34141 Korea School of Biological Sciences Seoul National University Seoul 151-747 Korea

Dear Editor,Flowering is a major developmental switch in the life cycle of flowering plants. FRIGIDA （FRI） activates FLOWERING LOCUS C （FLC） transcription, a major repressor of this switch regulating flow- ering time （Johanson et al., 2000）. FRI is highly conserved and many natural variations in FRI are found to affect flowering time. However, little is known about the molecular characteristics of FRI.

关键词： Flowering major developmental

经颅直流电刺激对职业高尔夫运动员一号木杆与短杆技术表现的影响

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经颅直流电刺激对职业高尔夫运动员一号木杆与短杆技术表现的影响