A potato late blight resistance gene protects against multiple Phytophthora species by recognizing a broadly conserved RXLR-WY effector

作     者：Xiao Lin Andrea Olave-Achury Robert Heal Marina Pais Kamil Witek Hee-Kyung Ahn He Zhao Shivani Bhanvadia Hari S.Karki Tianqiao Song Chih-hang Wu Hiroaki Adachi Sophien Kamoun Vivianne G.A.A.Vleeshouwers Jonathan D.G.Jones Xiao Lin;Andrea Olave-Achury;Robert Heal;Marina Pais;Kamil Witek;Hee-Kyung Ahn;He Zhao;Shivani Bhanvadia;Hari S.Karki;Tianqiao Song;Chih-hang Wu;Hiroaki Adachi;Sophien Kamoun;Vivianne G.A.A.Vleeshouwers;Jonathan D.G.Jones

作者机构：The Sainsbury LaboratoryUniversity of East AngliaNorwich Research ParkNR47UH NorwichUK Wageningen UR Plant BreedingWageningen University and ResearchDroevendaalsesteeg 16708 PB WageningenThe Netherlands Present address:Institute of Plant ProtectionJiangsu Academy of Agricultural SciencesNanjing 210014P.R.China Present address:Institute of Plant and Microbial BiologyAcademia SinicaTaipei 11529 Taiwan Present address:Laboratory of Crop EvolutionGraduate School of AgricultureKyoto UniversityMozumeMukoKyoto 617-0001Japan Present address:Lipman Family Farms21106 Six Ls Farm RdEsteroFloridaUnited States 

出 版 物：《Molecular Plant》 (分子植物（英文版）)

年 卷 期：2022年第15卷第9期

页      面：1457-1469页

核心收录：

学科分类：09[农学] 0904[农学-植物保护] 090401[农学-植物病理学] 090402[农学-农业昆虫与害虫防治] 

基　　金：financed by Biotechnology and Biological Sciences Research Council(BBSRC UK)grants BB/P021646/1 BB/S018832/1 and BB/M017834/1and the GatsbyCharitableFoundation(Coregrant to TSL) 

主　　题：Rpi-amr3 AVRamr3 potato late blight Phytophthora disease RXLR-WY effector Solanum americanum 

摘      要：Species of the genus Phytophthora,the plant killer,cause disease and reduce yields in many crop *** many Resistance to Phytophthora infestans(Rpi)genes effective against potato late blight have been cloned,few have been cloned against other Phytophthora *** Rpi genes encode nucleotide-binding domain,leucine-rich repeat-containing(NLR)immune receptor proteins that recognize RXLR(Arg-X-Leu-Arg)***,whether NLR proteins can recognize RXLR effectors from multiple Phytophthora species has rarely been ***,we identified a new RXLR-WY effector AVRamr3 from *** that is recognized by Rpi-amr3 from a wild Solanaceae species Solanum ***-amr3 associates with AVRamr3 in ***3 is broadly conserved in many different Phytophthora species,and the recognition of AVRamr3 homologs by Rpi-amr3 activates resistance against multiple Phytophthora pathogens,including the tobacco black shank disease and cacao black pod disease pathogens *** and ***-amr3 is thus the first characterized resistance gene that acts against *** or *** findings suggest a novel path to redeploy known R genes against different important plant pathogens.