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Importance of proper ventilator support and pulmonary rehabilitation in obese patients with heart failure:Two case reports

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World Journal of Clinical Cases 2023年第13期11卷 3029-3037页

作者： Eun-hee lim Sung-hee Park Yu Hui Won Physical Medicine and Rehabilitation Jeonbuk National University Medical SchoolJeonju 54907South Korea Department of Physical Medicine and Rehabilitation Jeonbuk National University Medical SchoolJeonju 54907South Korea Research Institute of Clinical Medicine of Jeonbuk National University Biomedical Research Institute of Jeonbuk National University HospitalJeonju 54907South Korea

BACKGROUND The optimal treatment for heart failure(HF)is a combination of appropriate *** the disease using only medical therapy is difficult in patients with HF,severe hypercapnia,and *** patients should first receive ventilator support followed by pulmonary rehabilitation(PR).CASE SUMMARY We report two cases in which arterial blood gas(ABG)improved and PR was possible with appropriate ventilator *** patients with extreme obesity complaining of worsening dyspnea–a 47-year-old woman and a 36-year-old man both diagnosed with HF–were hospitalized because of severe hypercapnia and *** proper medical treatment,hypercapnia and desaturation resolved in neither case,and both patients were transferred to the rehabilitation department for *** the time of the first consultation,the patients were bedridden because of *** demand was successfully reduced once noninvasive ventilation was *** the patients’dyspnea gradually improved to the point where they could be weaned off the ventilator during the daytime,they started engaging in functional training and aerobic *** 4 mo of followup,both patients were able to perform activities of daily living and maintain their lower body weight and normalized ABG *** Symptoms of patients with obesity and HF may improve once ABG levels are normalized through ventilator support and implementation of PR.

关键词： Noninvasive ventilation Heart failure Obesity Rehabilitation Dyspnea Case report

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Spatial phase-shifting interferometry with compensation of geometric errors based on genetic algorithm(Invited Paper)

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Chinese Optics Letters 2009年第12期7卷 1113-1116页

作者： Joonku Hahn Hwi Kim Yongjun lim Eun-hee Kim Byoungho Lee School of Electrical Engineering Seoul National University

We propose a novel spatial phase-shifting interferometry that exploits a genetic algorithm to compensate for geometric errors. Spatial phase-shifting interferometry is more suitable for measuring objects with properties that change rapidly in time than the temporal phase-shifting interferometry. However, it is more susceptible to the geometric errors since the positions at which interferograms are collected are different. In this letter, we propose a spatial phase-shifting interferometry with separate paths for object and reference waves. Also, the object wave estimate is parameterized in terms of geometric errors, and the error is compensated by using a genetic algorithm.

关键词： Spatial phase-shifting interferometry with compensation of geometric errors based on genetic algorithm

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Surface Waves in a Relativistic Plasma Stream Propagating in a Duct: Kinetic Theory

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Journal of Modern Physics 2022年第7期13卷 1065-1079页

作者： hee J. Lee Young kyung lim kyunggi-do Namyangju-si Hwado-eup Biryong-ro 321 South Korea Department of Radiation Oncology National Cancer Center Goyang South Korea

Dispersion relation of surface waves generated by a relativistic plasma stream in an infinite duct surrounded by vacuum is derived by means of relativistic Vlasov equation. The kinematic boundary condition imposed on the distribution function, the specular reflection conditions on the four sides of duct, can be satisfied by placing infinite number of fictitious surface charge sheets spaced by the duct widths. By placing appropriate fictitious surface charge sheets one can effectively deal with the extended electric field introduced in the Vlasov equation and treat kinetically the surface waves in semi-infinite, slab, and duct plasmas on equal ground. The relativistic duct dispersion relation is compared with the earlier non-relativistic surface wave dispersion relation.

关键词： Surface Wave Relativistic Plasma Duct Slab

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Simulation of Solid Particle Interactions Including Segregated Lamination by Using MPS Method

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Computer Modeling in Engineering & Sciences 2018年第7期116卷 11-29页

作者： kyung Sung Kim Moo-Hyun Kim Hakun Jang hee Chen Cho Tongmyong University BusanRepublic of Korea Texas A&M University College StationTXU.S.A Mississippi State University MSU.S.A

A new MPS(Moving Particle Semi-implicit)method is developed to simulate the behaviors and interactions of multiple fine solid particles as a *** fluid particles are affected by viscosity,so solid particles are affected by *** solid particle dynamics for landslides,dumping,and gravity sorting *** can be difficult to simulate using conventional MPS methods,are modeled in this paper using the developed multi-solid-particle MPS method that benefits from drawing comparisons with the corresponding fluid particle *** present MPS results for dumping solid particles are verified against the corresponding DEM(Discrete Element Method)*** shape and angle of repose for solid particles are shown to be highly dependent on the friction coefficient between *** peculiar phenomenon of segregated lamination(gravity sorting)among grains of different densities has been successfully reproduced using the multi-solid-particle MPS *** quality is found to be dependent on the densities and frictional coefficients of the constituent *** behavior of heterogeneous mixtures of multiple solid and liquid particles are also compared and *** newly developed tool offers a window into the physical dynamics of sedimentology that the broader geoscience community might benefit from.

关键词： Fine solid particle MPS(Moving Particle Semi-implicit) friction force land sliding dumping segregated lamination heterogeneous multiple particles gravity sorting

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Mesenchymal stem cells ameliorate B-cell-mediated immune responses and increase IL-10-expressing regulatory B cells in an EBI3-dependent manner

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Cellular & Molecular Immunology 2017年第11期14卷 895-908页

作者： kyung-Ah Cho Jun-Kyu Lee Yu-hee Kim Minhwa Park So-Youn Woo kyung-Ha Ryu Department of Microbiology School of MedicineEwha Womans UniversitySeoul 07985Republic of Korea Department of Pediatrics School of MedicineEwha Womans UniversitySeoul 07985Republic of Korea

Effector B cells are central contributors to the development of autoimmune disease by activating autoreactive T cells,producing pro-inflammatory cytokines and organizing ectopic lymphoid ***,IL-10-producing regulatory B(Breg)cells have pivotal roles in maintaining immunological tolerance and restraining excessive inflammation in autoinflammatory ***,regulating the equilibrium between antibody-producing effector B cells and Breg cells is critical for the treatment of autoimmune *** this study,we investigated the effect of human palatine tonsil-derived mesenchymal stem cells(T-MSCs)on estradiol(E2)-induced B-cell responses in vivo and in *** of T-MSC into E2-treated mice alleviated B-cell-mediated immune responses and increased the population of IL-10-producing Breg cells.T-MSCs regulated the B-cell populations by producing Epstein–Barr virus(EBV)-induced 3(EBI3),one of the two subunits of IL-35 that is the well-known inducer of Breg *** demonstrate a critical role of EBI3(IL-35)in vitro by depleting EBI3 in T-MSCs and by adding exogenous IL-35 to the culture *** together,our data suggest that IL-35-secreting MSCs may become an attractive therapeutic to treat B-cell-mediated autoimmune diseases via expanding Breg cells.

关键词： autoimmune disease B cells IL-35 mesenchymal stem cells

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Metal stents placement for refractory pancreatic duct stricture in children

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World Journal of Gastroenterology 2018年第3期24卷 408-414页

作者： In Sook Jeong Sung hee Lee Seak hee Oh Do Hyun Park kyung Mo Kim Department of Pediatrics University of Ulsan College of MedicineAsan Medical Center Children’s Hospital Department of Internal Medicine University of Ulsan College of MedicineAsan Medical Center

AIM To evaluate the use of fully covered self-expandable metal stents(FCSEMSs) for pancreatic duct strictures in children with chronic *** Eight patients with refractory benign dominant stricture of the main pancreatic duct(MPD) were enrolled through chart reviews between December 2014 and June 2017 in a single center. Endoscopic retrograde cholangiopancreatography(ERCP) with placement of a 6-mm FCSEMS with dual flaps was performed. Endoscopic removal of FCSEMSs was performed with a snare or rat-tooth forceps. All procedures were performed by a pediatric gastroenterologist. For the assessment of outcomes, technical and clinical success, adverse events, and stent patency were evaluated *** The placement and removal of the FCSEMSs were successful in all 8 patients. Five patients were boys and 3 were girls. The median age at initial FCSEMS placement was 12 years(range, 5-18 years). The diameters of all the inserted stents were 6 mm, and the lengths were 4-7 cm. The median indwelling time was 6 mo(range, 3-10 mo). No pancreatic sepsis, pancreatitis, cholestasis, or mortality occurred. There was no proximal and distal migration. All subjects showed a patent stent. On follow-up ERCP, the mean diameter of the stricture improved from 1.1 mm to 2.8 mm(P < 0.05), whereas that of upstream dilation improved from 8.4 mm to 6.3 mm(P < 0.05).CONCLUSION This initial experience showed that temporary FCSEMS placement is feasible and safe for the management of refractory benign MPD stricture in children.

关键词： Chronic pancreatitis Pancreatic duct Selfexpandable metal stent Child Endoscopic retrograde cholangiopancreatography

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Varicella-zoster virus meningitis after spinal anesthesia:A case report

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World Journal of Clinical Cases 2022年第25期10卷 9127-9131页

作者： Ye-Won Lee Byunghoon Yoo Yun hee lim Department of Anesthesiology and Pain Medicine College of MedicineInje UniversitySanggye Paik HospitalSeoul 01757South Korea

BACKGROUND Headache is a common complication of regional *** treatment of post spinal anesthesia headache varies depending on the *** meningitis is rare,it can cause significant harm to the *** dural puncture headache and septic meningitis are the most commonly suspected causes of post spinal anesthesia headache;however,other causes should also be *** SUMMARY A 69-year-old woman was scheduled for varicose vein stripping surgery under spinal *** procedure was performed aseptically,and surgery was completed without any *** 4 d,the patient visited the emergency room with complaints of headache,nausea,and *** examination revealed that the patient was *** the history of spinal anesthesia,post dural puncture headache and septic meningitis was initially suspected,and the patient was treated with empirical ***,varicella-zoster virus PCR test result was positive,and all other test results were *** patient was diagnosed with meningitis caused by varicella-zoster virus and was treated with acyclovir for 5 *** headache improved,and the patient was discharged without any *** Viral meningitis due to virus reactivation may cause headache after regional ***,clinicians should consider multiple etiologies of headache.

关键词： Aseptic meningitis Headache Regional anesthesia Spinal anesthesia Varicella zoster virus infection Case report

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Retrospective analysis of extra-gastrointestinal stromal tumors

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World Journal of Gastroenterology 2015年第6期21卷 1845-1850页

作者： Jun Ho Yi Byeong-Bae Park Jung Hun Kang In Gyu Hwang Dong Bok Shin Sun Jin Sym hee kyung Ahn Soon Il Lee Do Hyoung lim Keon Woo Park Young-Woong Won Sung hee lim Se Hoon Park Division of Hematology-Oncology Department of Internal Medicine Hanyang University Seoul Hospital Division of Hematology-Oncology Department of Internal Medicine Gyeongsang National University School of Medicine Division of Hematology-Oncology Department of Internal Medicine Chung-Ang University Hospital ChungAng University College of Medicine Division of Hematology-Oncology Department of Internal MedicineGachon University Gil Hospital Department of Hematology-Oncology Dankook University School of Medicine Division of Hematology and Oncology Department of Internal Medicine Hanyang University Guri Hospital Hanyang University College of Medicine Division of HematologyOncology Department of Medicine Sungkyunkwan University Samsung Medical Center Cancer hospital

AIM:To investigate the clinicopathologic features of patients with extra-gastrointestinal stromal tumors(EGISTs)in South ***:A total of 51 patients with an EGIST were *** clinicopathologic features,including sex,age,location,tumor size,histology,mitotic rate,immunohistochemical features,genetic status and survival data,were ***:The median age was 55 years(range:29-80years),and male:female ratio was 1:*** most common site was in the mesentery(n=15)followed by the retroperitoneum(n=13)and omentum(n=8).The median tumor size was 9.0 cm(range:2.6-30.0cm)and the median mitotic rate was 5.0/50HPF.(1/50-185/50).KIT was analyzed in 16,which revealed 10cases with wild-type KIT and 6 cases with an exon *** 51 patients,31 patients had undergone surgery,and 10 had unresectable disease and had taken palliative imatinib,which resulted in 22.7 mo of progression-free *** the patients who had undergone surgery,18 did not take adjuvant imatinib,and 8 of these were categorized as"high risk"according to the risk ***,the relapse-free survival was not different(P=0.157)between two ***:Because the biologic behaviors of GISTs differ according to the location of the tumor,a more stratified strategy is required for managing EGISTs including incorporation of molecular features.

关键词： Gastrointestinal stromal tumor Survival Imatinib R

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Primary central nervous system lymphoma presenting as a single choroidal lesion mimicking metastasis:A case report

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World Journal of Clinical Cases 2022年第4期10卷 1291-1295页

作者： hee Ryeong Jang Kyu-Hyoung lim kyungyul Lee Department of Internal Medicine Kangwon National University HospitalKangwon National University School of MedicineChuncheon 24289South Korea Department of Pathology Kangwon National University HospitalKangwon National University School of MedicineChuncheon 24289South Korea

BACKGROUND Primary choroidal lymphoma is usually an indolent B-cell lymphoma and rarely progresses to extraocular ***,we report a case of primary choroidal lymphoma diagnosed as diffuse large B-cell lymphoma(DLBL),which progressed to the brain parenchyma after 4 *** SUMMARY A 78-year-old man presented with diminution of vision in his right eye.A choroidal lesion suspected of metastatic lesion was observed in the right eye by ophthalmologic *** discover the primary tumor,imaging investigations were performed but no malignant lesion was *** 4 mo,the patient returned to the clinic presenting with neurological *** magnetic resonance imaging revealed an abnormal contrast-enhancing mass in the left cerebellum.A stereotactic biopsy was performed,and DLBL was *** patient received the high dose methotrexate-based chemotherapy and he achieved complete *** Primary choroidal lymphoma is usually known to have a benign clinical course without systemic *** present a rare case of primary choroidal lymphoma diagnosed as DLBL that progressed to the brain parenchyma within months.

关键词： Primary choroidal lymphoma Diffuse large B-cell lymphoma Primary central nervous system lymphoma Case report

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Tribology of multilayer coatings for wear reduction: A review

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Friction 2017年第3期5卷 248-262页

作者： Mahdi KHADEM Oleksiy V.PENKOV hee-kyung YANG Dae-Eun KIM Department of Mechanical Engineering Yonsei University Seoul 03722 Republic of KoreaCenter for Nano-Wear Yonsei University Seoul 03722 Republic of Korea Center for Nano-Wear Yonsei University Seoul 03722 Republic of Korea Department of Mechanical Engineering Yonsei University Seoul 03722 Republic of Korea

Friction and wear phenomena encountered in mechanical systems with moving components are directly related to efficiency,reliability and life of the ***,minimizing and controlling these phenomena to achieve the desired system performance is *** the numerous strategies developed for reducing friction and wear,coatings have been successfully utilized in various engineering applications to mitigate tribological *** of the benefits of coatings is that they may be fabricated using a variety of materials in several different forms and structures to satisfy the requirements of the operating *** many types,coatings that are comprised of a combination of materials in the form of a multilayer have been gaining much interest due to the added degree of freedom in tailoring the coating *** this paper,the properties and development status of multilayer coating systems for tribological applications were reviewed with the aim to gain a better understanding regarding their advantages and ***,focus was given to Ti-based and Cr-based coatings since Ti and Cr were identified as important elements in multilayer coating *** was given to materials,design concepts,mechanical properties,deposition method,and friction and wear characteristics of these types of coatings.

关键词： multilayer coating friction wear tribology

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