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A Systematic Molecular Dynamics Investigation on the Graphene Polymer Nanocomposites for Bulletproofing

Computers, Materials & Continua 2020年第12期65卷 2009-2032页

作者： Hamidreza Noori Zi Goangseup Bohayra Mortazavi Alessandro Di Pierro Emad Jomehzadeh Xiaoying Zhuang kim Sang-Hyun Timon Rabczuk Institute of Structural Mechanics Bauhaus-Universität WeimarWeimarD-99423Germany Chair of Computational Science and Simulation Technology Department of Mathematics and PhysicsLeibniz Universität HannoverHannover30157Germany Cluster of Excellence PhoenixD(Photonics Opticsand Engineering-Innovation Across Disciplines)Gottfried Wilhelm Leibniz Universität HannoverHannoverGermany Dipartimento di ScienzaApplicata e Tecnologia Politecnico di TorinoAlessandria CampusAlessandria15121Italy Faculty of Mechanical and Material Engineering Graduate University of Advanced TechnologyKermanIran School of Civil Environmental and Architectural EngineeringKorea UniversitySeoulKorea Chief Research Engineer Mechanical Engineering R&D LabLIG Nex1Seung NamKorea Division of Computational Mechanics Ton Duc Thang UniversityHo Chi Minh CityVietnam Faculty of Civil Engineering Ton Duc Thang UniversityHo Chi Minh CityVietnam

In modern physics and fabrication technology,simulation of projectile and target collision is vital to improve design in some critical applications,like;bulletproofing and medical ***,the most prominent member of two dimensional materials presents ultrahigh tensile strength and ***,polydimethylsiloxane(PDMS)is one of the most important elastomeric materials with a high extensive application area,ranging from medical,fabric,and interface *** this work we considered graphene/PDMS structures to explore the bullet resistance of resulting *** this aim,extensive molecular dynamic simulations were carried out to identify the penetration of bullet through the graphene and PDMS composite *** this paper,we simulate the impact of a diamond bullet with different velocities on the composites made of single-or bi-layer graphene placed in different positions of PDMS *** underlying mechanism concerning how the PDMS improves the resistance of graphene against impact loading is *** discuss that with the same content of graphene,placing the graphene in between the PDMS result in enhanced bullet *** work comparatively examines the enhancement in design of polymer nanocomposites to improve their bulletproofing response and the obtained results may serve as valuable guide for future experimental and theoretical studies.

关键词： Graphene nanocomposites bulletproofing impact PDMS

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Selective and localized laser annealing effect for high- performance flexible multilayer MoS2 thin-film transistors

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Nano Research 2014年第8期7卷 1137-1145页

作者： Hyukjun Kwon Woong Choi Daeho Lee Yunsung Lee Junyeon Kwon Byungwook Yoo Costas P. Grigoropoulos Sunkook kim Department of Mechanical Engineering University of California Berkeley CA 94720-1740 USA School of Advanced Materials Engineering Kookmin University Seoul 136-702 South Korea Department of Mechanical Engineering 6achon University Seongnam-si Gyeonggi 461-701 South Korea Department of Electronics and Radio Engineering Kyung Hee University Gyeonggi 446-70 I South Korea Flexible Display Research Center Korea Electronics Technology Institute Seongnam Gyeonggi 463-816 South Korea

We report the use of ultra-short, pulsed-laser annealed Ti/Au contacts to enhance the performance of multilayer MoS2 field effect transistors (FETs) on flexible plastic substrates without thermal damage. An analysis of the temperature distribution, based on finite difference methods, enabled understanding of the compatibility of our picosecond laser annealing for flexible poly(ethylene naphthalate) (PEN) substrates with low thermal budget (< 200 °C). The reduced contact resistance after laser annealing provided a significant improvement in transistor performance including higher peak field-effect mobility (from 24.84 to 44.84 cm2·V−1·s−1), increased output resistance (0.42 MΩ at V gs − V th = 20 V, a three-fold increase), a six-fold increase in the self-gain, and decreased sub-threshold swing. Transmission electron microscopy analysis and current-voltage measurements suggested that the reduced contact resistance resulted from the decrease of Schottky barrier width at the MoS2-metal junction. These results demonstrate that selective contact laser annealing is an attractive technology for fabricating low-resistivity metal-semiconductor junctions, providing important implications for the application of high-performance two-dimensional semiconductor FETs in flexible electronics.

关键词：激光退火薄膜晶体管 MoS2 柔性性能退火效应透射电子显微镜分析场效应晶体管

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Growth-controlled synthesis of polymer-coated colloidal-gold nanoparticles using electrospray-based chemical reduction

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Particuology 2021年第4期19卷 72-81页

作者： Mohamed Hasaan Hussain Noor Fitrah Abu Bakar kim-Fatt Low Ana Najwa Mustapa Fatmawati Adam Mohd Nazli Naim I.Wuled Lenggoroe Faculty of Chemical Engineering Universiti Teknologi MARAShah AlamSelangor 40450Malaysia Faculty of Applied Sciences Universiti Teknologi MARAPerak BranchTapah CampusTapah RoadPerak 35400Malaysia Faculty of Chemical and Process Engineering Technology Universiti Malaysia PahangLebuh Raya Tun RazakGambangPahang 26300Malaysia Department of Process and Food Engineering Faculty of EngineeringUniversiti Putra MalaysiaSerdangSelangor 43400Malaysia Graduate School of Bio-Applications and Systems Engineering Tokyo University of Agriculture and TechnologyNaka Cho2-24-16KoganeiTokyo 184-8588Japan Department Chemical of Engineering Tokyo University of Agriculture and TechnologyNaka Cho2-24-16KoganeiTokyo 184-8588Japan

In this study,the controlled nucleation and growth of gold nanoparticles(GNPs)were investigated using a self-repelled mist in a liquid chemical reaction *** electrospray-based chemical reduction method was conducted in the aqueous region and at room temperature to synthesize the polymeric-stabilized gold *** electrospray technique was used to atomize a hydrogen tetrachloraurate(III)(HAuCl4)precursor solution into electrostatically charged *** atomized droplets were dispersed in an aqueous reaction bath containing L-ascorbic acid as a reducing agent and polyvinylpyrrolidone(PVP)as a *** effect of the electrospray parameters,specifically the flow rate and electrospray droplet size,as well as the reaction conditions such as the concentration of reactants,pH,and stabilizer(PVP),were *** mean diameter of the GNPs increased from around 4 to 9 nm with an increase in the electrospray flow rate,droplet size,and current passing through the electrospray *** and monodispersed GNPs were synthesized at a relatively high flow rate of 2 mL/h and a moderate concentration of 2 mM of precursor *** smallest-sized GNP with a high monodispersity was obtained in the reaction bath at a high pH of 10.5 and in the presence of *** is expected that continuous and mass production of the engineered GNPs and other noble metal nanoparticles could be established for scaling up nanoparticle production via the proposed electrospray-based chemical reduction method.

关键词： Electrospray Gold nanoparticles Chemical reduction method L-ascorbic acid PVP Aqueous medium

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Three-dimensional label-free morphology of CD8+T cells as a sepsis biomarker

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Light(Science & Applications) 2023年第12期12卷 2565-2576页

作者： MinDong Sung Jong Hyun kim Hyun-Seok Min Sooyoung Jang JaeSeong Hong Bo Kyu Choi JuHye Shin Kyung Soo Chung Yu Rang Park Division of Pulmonary and Critical Care Medicine Department of Internal MedicineYonsei University College of MedicineSeoulRepublic of Korea Department of Biomedical Systems Informatics Yonsei University College of MedicineSeoulRepublic of Korea Tomocube Inc155 Sinseong-roShinsung-dongYuseong-guDaejeonRepublic of Korea

Sepsis is a dysregulated immune response to infection that leads to organ dysfunction and is associated with a high incidence and mortality *** lack of reliable biomarkers for diagnosing and prognosis of sepsis is a major challenge in its *** aimed to investigate the potential of three-dimensional label-free CD8+T cell morphology as a biomarker for *** study included three-time points in the sepsis recovery cohort(N=8)and healthy controls(N=20).Morphological features and spatial distribution within cells were compared among the patients'*** developed a deep learning model to predict the diagnosis and prognosis of sepsis using the internal cell *** between the morphological features and clinical indices were *** morphological features and spatial distribution differed significantly between patients with sepsis and healthy controls and between the survival and non-survival *** model for predicting the diagnosis and prognosis of sepsis showed an area under the receiver operating characteristic curve of nearly 100%with only a few cells,and a strong correlation between the morphological features and clinical indices was *** study highlights the potential of three-dimensional label-free CD8+T cell morphology as a promising biomarker for *** approach is rapid,requires a minimum amount of blood samples,and has the potential to provide valuable information for the early diagnosis and prognosis of sepsis.

关键词： sepsis diagnosis Morphological

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Liver function alterations after laparoscopy-assisted gastrectomy for gastric cancer and its clinical significance

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World Journal of Gastroenterology 2011年第3期17卷 372-378页

作者： Gui-Ae Jeong Gyu-Seok Cho Eung-Jin Shin Moon-Soo Lee Hyung-Chul kim Ok-Pyung Song Department of Surgery Soonchunhyang University College of Medicine

AIM: To evaluate the factors associated with liver function alterations after laparoscopy-assisted gastrectomy (LAG) for gastric cancer. METHODS: We collected the data of gastrectomy patients with gastric cancer and divided them into 2 groups: open gastrectomy (OG) and LAG. We also collected the data of patients with colon cancer to evaluate the effect of liver manipulations during surgery on liver function alterations. Serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), total bilirubin, and alkaline phosphatase were measured on the preoperative day and postoperative day 1 (POD1), POD3, POD5, and POD7. RESULTS: No changes in liver function were observed after the operation in patients with colon cancer (n = 121). However, in gastric cancer patients (n = 215), AST and ALT levels increased until POD5 compared to those in colon cancer patients and these findings were observed both in the LAG and OG without a significant difference except at POD1. The mean hepatic enzyme levels at POD1 in the LAG group were significantly higher than those in the OG group (P = 0.047 for AST and P = 0.039 for ALT). The factors associated with elevated ALT on POD1 in patients with gastric cancer were body mass index (P < 0.001), operation time (P < 0.001), intraoperative hepatic injury (P = 0.048), and ligation of an aberrant left hepatic artery (P = 0.052) but not type of operation (OG vs LAG, P = 0.094). CONCLUSION: We conclude that the liver function alteration after LAG may have been caused by direct liver manipulation or aberrant hepatic artery ligation rather than the CO2 pneumoperitoneum.

关键词：肝功能腹腔镜胃癌临床意义谷草转氨酶手术操作 LAG 谷丙转氨酶

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面向对象数据库系统:诺言·现实·前景(1)

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计算机科学 1994年第4期21卷 31-36,5页

作者： Won kim

过去十年里,面向对象技术已逐步用于程序设计语言,用户界面、数据库、操作系统、专家系统、等等。尽管如此,关于面向对象数据库系统、扩充了面向对象功能的关系系统、甚至这些系统的必要性,在用户、商业杂志及卖主中仍有许多谬传和混淆... 详细信息

过去十年里,面向对象技术已逐步用于程序设计语言,用户界面、数据库、操作系统、专家系统、等等。尽管如此,关于面向对象数据库系统、扩充了面向对象功能的关系系统、甚至这些系统的必要性,在用户、商业杂志及卖主中仍有许多谬传和混淆。本文旨在回顾面向对象数据库系统的承诺,分析其现实性,以及如何通过与关系技术联合起来以履行其诺言。

关键词：数据库面向对象程序语言

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Portable System for CWA Detection Using Micro Array Gas Sensor

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稀有金属材料与工程 2006年第A3期35卷 124-128页

作者： J.H.Kwak Y.T.Lim G.H.kim N.J.Choi H.D.Park G.H.Rue J.S.Huh J.C.kim D.D.Lee School of Electrical Engineering and Computer Science Kyungpook National UniversityDaegu 1370Korea Electronics and Telecommunications Research Institute Future Technology Research Division New Functional Information Devices TeamGajeongYuseong-GuDaejeon 161 Korea Korea Electronics Technology Institute Yatap-DongBundang-GuSeongnam-SiGyeonggi-Do #68Korea Department of Materials Science and Metallurgy Kyungpook National UniversityDaegu 1370Korea Department of Chemical Engineering Kyungpook National UniversityDaegu 1370Korea

Biochemistry weapon is raising new tools of war and *** research is an experiment about portable system for CWAs (chemical warfare agents) detection using micro array gas *** were divided into four types such as blood, nerve,vesicant,and choking *** detect various CWAs,semiconductor thick film sensor array based on tin oxide was fabricated and their gas responses were *** temperature was range of 250℃to 350℃and gas concentration was range of 0.1μg/g to 10μg/*** array was measured as operating temperatures,concentrations for four simulant agents of *** parameters from results were carried out classification among CWAs through the principal component analysis (PCA).Also,classification of gases is studied using adaptive resonance theory (ART) that is one of neural network *** displayed using PDA system.

关键词： SnO2 chemical warfare agents(CWAs) portable system ART array PCA

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Optimization of rotor shape for constant torque improvement and radial magnetic force minimization

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Journal of Central South University 2012年第2期19卷 357-364页

作者： CHO Gyu-won WOO Seok-hyun JI Seung-hun PARK Kyoung-won JANG Ki-bong kim Gyu-tak School of Mechatronics Changwon National University

The design of notch and barrier was optimized in order to improve the characteristics of constant torque while minimizing the cogging torque that occurs as a result of teeth and slot structure. The barrier was installed in order to minimize the cogging torque and torque ripple by finite element method (FEM) with a reduced barrier width toward the center of magnetic pole. The position and width of notch, which can offset cogging torque, can be calculated with energy distribution of air-gap using Fourier series. The optimized model demonstrates a 60% decrease in the cogging torque, a 75.3% decrease in the torque ripple and a 3% increase in the operating torque when compared with the basic model.

关键词：优化模型恒转矩径向磁力齿槽转矩形状转子转矩脉动傅立叶级数

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Artificial Nanoscale Erythrocytes from Clinically Relevant Compounds for Enhancing Cancer Immunotherapy

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Nano-Micro Letters 2020年第7期12卷 156-174页

作者： Wenquan Ou Kang Sik Nam Dae Hoon Park Jungho Hwang Sae Kwang Ku Chul Soon Yong Jong Oh kim Jeong Hoon Byeon College of Pharmacy Yeungnam UniversityGyeongsan 38541Republic of Korea School of Mechanical Engineering Yonsei UniversitySeoul 03722Republic of Korea College of Korean Medicine Daegu Haany UniversityGyeongsan 38610Republic of Korea School of Mechanical Engineering Yeungnam UniversityGyeongsan 38541Republic of Korea

Because of enhanced e cacy and lower side e ects,cancer immunotherapies have recently been extensively investigated in clinical trials to overcome the limitations of conventional cancer *** engineering attempts have been made to build nanosystems even including stimulus nanomaterials for the e cient delivery of antigens,adjuvants,or anticancer drugs to improve immunogenic cancer cell death,this requires huge R&D e orts and investment for clinically relevant findings to be approved for translation of the *** this end,in this study,an air–liquid two-phase electrospray was developed for stable bubble pressing under a balance between mechanical and electrical parameters of the spray to continuously produce biomimetic nanosystems consisting of only clinically relevant compounds[paclitaxel-loaded fake blood cell Eudragit particle(Eu-FBCP/PTX)]to provide a conceptual leap for the timely development of translatable chemo-immunotherapeutic *** was pursued as the e cacy of systems for delivering anticancer agents that has been mainly influenced by nanosystem shape because of its relevance to transporting behavior to organs,blood circulation,and cell–membrane *** resulting Eu-FBCP/PTX nanosystems exhibiting phagocytic and micropinocytic uptake behaviors can confer better e cacy in chemo-immunotherapeutics in the absence and presence of anti-PD-L1 antibodies than similar sized PTX-loaded spherical Eu particles(Eu-s/PTX).

关键词： Cancer immunotherapies Air–liquid two-phase electrospray Paclitaxel-loaded fake blood cell Eudragit particle Translatable chemo-immunotherapeutic nanosystems Anti-PD-L1 antibodies

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Programming of macrophages by UV-irradiated apoptotic cancer cells inhibits cancer progression and lung metastasis

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Cellular & Molecular Immunology 2019年第11期16卷 851-867页

作者： Yong-Bae kim Young-Ho Ahn Ji-Hae Jung Ye-Ji Lee Jin-Hwa Lee Jihee Lee Kang Tissue Injury Defense Research Center College of MedicineEwha Womans UniversitySeoul 07804Korea Department of Molecular Medicine College of MedicineEwha Womans UniversitySeoul 07804Korea Department of Physiology College of MedicineEwha Womans UniversitySeoul 07804Korea Department of Internal Medicine College of MedicineEwha Womans UniversitySeoul 07804Korea

Apoptotic cell clearance by phagocytes is essential in tissue *** demonstrated that conditioned medium(CM)from macrophages exposed to apoptotic cancer cells inhibits the TGFβ1-induced epithelial–mesenchymal transition(EMT),migration,and invasion of cancer *** 344SQ(ApoSQ)cell-induced PPARγactivity in macrophages increased the levels of PTEN,which was secreted in *** PTEN was taken up by recipient lung cancer ***-exposed CM from PTEN knockdown cells failed to enhance PTEN in 344SQ cells,restore cellular polarity,or exert anti-EMT and anti-invasive *** CM that was deficient in PPARγligands,including 15-HETE,lipoxin A4,and 15d-PGJ2,could not reverse the suppression of PPARγactivity or the PTEN increase in 344SQ cells and consequently failed to prevent the EMT ***,a single injection of ApoSQ cells inhibited lung metastasis in syngeneic immunocompetent mice with enhanced PPARγ/PTEN signaling both in tumorassociated macrophages and in tumor ***γantagonist GW9662 reversed the signaling by PPARγ/PTEN;the reduction in EMT-activating transcription factors,such as Snai1 and Zeb1;and the antimetastatic effect of the ApoSQ ***,the injection of apoptotic lung cancer cells may offer a new strategy for the prevention of lung metastasis.

关键词： Apoptotic cell clearance EMT Metastasis Exosomal PTEN PPARγligands

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