检索结果-南通市图书馆

High Prevalence of Genetic Alterations in Infantile-Onset Cardiomyopathy

Congenital Heart Disease 2021年第4期16卷 397-410页

作者： Junsung Park Go Hun Seo Yena Lee Yunha Choi Minji Kang Hyo-Sang Do Young-Hwue kim Jeong Jin Yu Ellen Ai-Rhan kim Euiseok Jung Byong Sop Lee Jae Suk Baek Beom Hee Lee Department of Pediatrics Asan Medical CenterUniversity of Ulsan College of MedicineSeoulKorea billion Inc.SeoulKorea Genome Research Center for Birth Defects and Genetic Diseases Asan Institute for Life SciencesAsan Medical CenterSeoulKorea Division of Cardiology Department of PediatricsAsan Medical CenterUniversity of Ulsan College of MedicineSeoulKorea Division of Neonatology Department of PediatricsAsan Medical CenterUniversity of Ulsan College of MedicineSeoulKorea Medical Genetics Center Asan Medical Center Children’s HospitalUniversity of Ulsan College of MedicineSeoulKorea

Background and Method:The genetic cause of infantile-onset cardiomyopathy is rarely ***,we conducted whole exome sequencing(WES)and mitochondrial DNA(mtDNA)sequencing in eight patients with infantile-onset cardiomyopathy to identify genetic ***:Among these patients,two(25%)had dilated cardiomyopathy(DCMP),two(25%)had left ventricular non-compaction(LVNC),and four(50%)had hypertrophic cardiomyopathy(HCMP).Except four patients identified prenatally,the remaining patients presented at a median age of 85.5 *** identified genetic variants in a total of seven(87.5%)patients and mtDNA sequencing in the other ***1 and MYH7 variants were identified in the two patients with DCMP;MYH11 and MYLK2 variants in the two patients with LVNC;HRAS,BRAF,and MYH7 variants in three patients with HCMP;and MT-ND1 variant in one patient with HCMP having high blood lactic acid *** the eight variants,four were classified as pathogenic or likely-pathogenic according to the American College of Medical Genetics(ACMG)guidelines,and the remaining were identified as variants of unknown significance(VUSs).Three pathogenic mutations were de novo,whereas four(likely-pathogenic or VUSs)were inherited from a respective parent,excluding one variant where parental testing was unavailable,questioning whether these inherited variants are *** patients died before 3 months of ***:Genomic studies,such as WES with additional mtDNA sequencing,can identify a genetic variant in high proportions of patients with infantile-onset *** clinical implication of the parentally inherited variant needs to be assessed in a larger patient and family cohort with a longitudinal follow-up.

关键词： Cardiomyopathy whole exome sequencing infantile-onset

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effectiveness of gastric cancer screening programs in South Korea:Organized vs opportunistic models

引用

World Journal of Gastroenterology 2013年第5期19卷 736-741页

作者： Beom Jin kim Chae Heo Byoung Kwon kim Jae Yeol kim Jae Gyu kim Department of Internal Medicine Chung-Ang University College of MedicineHeukseok-dongDongjak-guSeoul 156-755South Korea Department of Pathology Green Cross Reference Laboratory314 Pojung-dongGiheung-guYongin-siKyunggi-do 446-913South Korea

AIM:To investigate the outcome and effectiveness of two screening programs,National Cancer Screening Program(NCSP)and opportunistic screening(OS),for the detection of gastric cancer. METHODS:A total of 45 654 subjects underwent upper endoscopy as part of the NCSP or OS at the Chung-Ang University Healthcare System in Korea between January 2007 and December *** study population was comprised of subjects over the age of 40 *** specifically,subjects who took part in the NCSP were Medicaid recipients and beneficiaries of the National Health Insurance *** photo-graphs from the endoscopies diagnosed as gastric cancer were reviewed by two experienced endoscopists. RESULTS:The mean age of the screened subjects was 55 years for men and 54 years for women.A total of 126 cases(0.28%)of gastric cancer were detected from both screening programs;100 cases(0.3%)from NCSP and in 26 cases(0.2%)from *** proportion of early gastric cancer(EGC)detected in NCSP was higher than that in OS(74.0%vs 53.8%,P=0.046). Among the 34 416 screenees in NCSP,6585(19.1%) underwent upper endoscopy every other year as *** the 11 238 screenees in OS,3050(27.1%) underwent upper endoscopy at least once every two years during the study *** detection rate of gastric cancer was found to be significantly higher during irregular follow-up than during regular follow-up in both screening programs(0.3%vs 0.2%,P=0.036).A higher incidence of EGC than advanced gastric cancer was observed during regular follow-up compared with irregular follow-up. CONCLUSION:Compliance to the screening program is more important than the type of screening system used.

关键词： Gastric cancer National Cancer Screening Program Opportunistic screening Early gastric cancer

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Experimental evidence of Bloch surface waves on photonic crystals with thin-film LiNbO_3 as a top layer

引用

光子学研究：英文版 2017年第6期5卷 168-172页

作者： TATIANA KOVALEVICH DJAFFAR BELHARET LAURENT ROBERT MYUN-SIK kim HANS PETER HERZIG THIERRY GROSJEAN MARIA-PILAR BERNAL Département d'Optique P.M.Duffieux Institut FEMTO-ST UMR 6174 CNRS Université Bourgogne Franche-Comté Optics & Photonics Technology Laboratory Ecole Polytechnique Fédérale de Lausanne (EPFL)

Strong nonlinear, electro-optical, and thermo-optical properties of lithium niobate(LN) have gained much attention. However, the implementation of LiNbO_3 in real devices is not a trivial task due to difficulties in manufacturing and handling thin-film LN. In this study, we investigate an optical device where the Bloch surface wave(BSW) propagates on the thin-film LN to unlock its properties. First, access to the LN film from air(or open space) is important to exploit its properties. Second, for sustaining the BSW, one-dimensional photonic crystal(1DPhC) is necessary to be fabricated under the thin-film LN. We consider two material platforms to realize such a device: bulk LN and commercial thin-film LN. Clear reflectance dips observed in far-field measurements demonstrate the propagation of BSWs on top of the LN surface of the designed 1DPhCs.

关键词： LN Li Experimental evidence of Bloch surface waves on photonic crystals with thin-film LiNbO3 as a top layer

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

CALCULATION AND IMPROVEMENT OF DYNAMIC CHARACTERISTICS OF CENTRIFUGE

引用

Chinese Journal of Mechanical Engineering 2001年第1期14卷 32-35,39页

作者： Yang Yun Wang Zheng Department of Engineering Mechanics, Qinghua University kim Lock Song Institute of Biophysics, Chinese Academy of Sciences 清华大学工程力学系北京中科院生物物理所北京

The modeling of the rotor support system of a typical centrifuge is discussed. The impedance matching method, cooperating with Riccati transfer matrix method and modal analysis method are adopted to calculate its dynamic characteristics. The influences of the main parts to the critical speeds are analyzed. Based on the analysis, a critical speed in the operating speed range is tuned successfully, and thus the dynamic characteristics of the centrifuge are much improved.

关键词： Centrifuge Dynamic characteristics Impedance matching method

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Knowledge and attitude toward COVID-19 among healthcare workers at District 2 Hospital, Ho Chi Minh City

引用

Asian Pacific Journal of Tropical Medicine 2020年第6期13卷 260-265页

作者： Huynh Giao Nguyen Thi Ngoc Han Tran Van Khanh Vo kim Ngan Vo Van Tam Pham Le An Faculty of Public Health University of Medicine and Pharmacy at Ho Chi Minh CityVietnam Department of Infectious Diseases University Medical Center Ho Chi Minh CityVietnam Department of Scientific Research District 2 HospitalHo Chi Minh CityVietnam Department of Nursing District 2 HospitalHo Chi Minh CityVietnam Faculty of Nursing and Medical Technology University of Medicine Pham Ngoc Thach at Ho Chi Minh CityVietnam Center for the Training of Family Medicine Faculty of MedicineUniversity of Medicine and Pharmacy at Ho Chi Minh CityVietnam

Objective:To assess the knowledge and attitude toward coronavirus disease-2019(COVID-19)among healthcare workers at District 2 Hospital in Ho Chi Minh City(HCMC).Methods:A cross-sectional study was performed between January 2020 and February 2020 at District 2 Hospital.A systematic random sampling strategy was carried out and the data was collected through a self-administered questionnaire of the knowledge and attitude of healthcare workers regarding *** analysis was reported to describe the demographic,mean knowledge and attitude score of healthcare *** statistics including t-test,ANOVA and Spearman’s correlation were used to evaluate the relationship between study ***:A total of 327 eligible healthcare workers had a mean score of knowledge and attitude of 8.17±1.3(range 4-10)and 1.86±0.43(range 1-5),*** showed good knowledge and a positive ***,approximately two thirds of the participants knew the mode of transmission,the isolation period and treatment(67.0%,65.8%,and 58.4%,respectively),and 82.3%and 79.8%,respectively,held positive attitude regarding the risk of personal and family members getting *** was a negative correlation between knowledge scores and attitude scores(r=-0.21,P<0.001).Additionally,healthcare workerspredominately used social media to inform themselves about COVID-19(91.1%).Conclusions:The majority of healthcare workers had good knowledge and positive attitude toward ***,the level of some knowledge and attitude lower than that expected for their position level towards the *** education interventions and campaigns are required for healthcare workers.

关键词： Knowledge Attitude COVID-19 Healthcare worker District 2 Hospital

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Biotechnological valorization of algal biomass:an overview

引用

Systems Microbiology and Biomanufacturing 2021年第2期1卷 131-141页

作者： A.Naresh Kumar Jeong-Jun Yoon Gopalakrishnan Kumar Sang-Hyoun kim School of Civil and Environmental Engineering Yonsei UniversitySeoul 03722Republic of Korea Intelligent Sustainable Materials R&BD Group Korea Institute of Industrial Technology(KITECH)CheonanChungnam 31056Republic of Korea

Algal biomass has significant advantages over terrestrial plants in terms of CO2 sequestration,biomass productivity,waste-water treatment along with multiple biobased products *** versatility and high carbohydrate content of microalgal biomass act as a potential alternative feedstock to fossil resources and contribute towards the biobased economy *** biomass utilization would play a key role to establish sustainable bioprocess development and technology translation to the industrial *** this framework,the present review discusses the renewable resource potential of algal biomass and its complete utilization for multiple biobased products synthesis in a closed-loop biorefinery *** methods are discussed to obtain high biomass growth and pretreatments to obtain the maximum sugars ***,combined bioprocesses were discussed for the production of biohydrogen,biomethane,bioethanol,short-chain fatty acids(SCFA),medium-chain fatty acids(MCFA),and biopolymers in a closed-loop approach.

关键词： Algal biomass Biorefinery Bioeconomy Closed loop Biohydrogen

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique

引用

Asian Journal of Andrology 2018年第1期20卷 80-84页

作者： Dae Yul Yang Kyungtae Ko seong Ho Lee Du Geon Moon Jong Wook kim Won Ki Lee Department of Urology College of Medicine Hallym University Chuncheon Korea Department of Urology College of Medicine Korea University Seoul Korea.

There is no safe and effective standard method for glans penis augmentation. Furthermore, there has been scant research on glans penis augmentation due to a poor understanding of glans anatomy, technical difficulty, and a lack of suitable substances for augmentation. Cross-linked dextran gel is a newly developed filler for soft-tissue augmentation. We evaluated the efficacy and safety of using a novel technique to inject cross-linked dextran gel for glans penis augmentation during a 24-week follow-up study. This prospective, single-arm, multicenter study enrolled twenty healthy adult men who underwent glans penis augmentation between June and August 2013. Cross-linked dextran gel was injected into the glans penis using a simple and easy technique. The sizes of the glans penis and individual satisfaction were assessed. Any adverse event was also reported. A total of 18 individuals were analyzed; two of them were lost to follow-up. The mean procedure time and injected volume were about 30 rain and 6.6 ＋- 0.9 ml, respectively. The mean surface areas of the glans at baseline and 24 weeks were 20.0 _＋ 3.5 cm2 and 33.6 -＋ 5.4 cm2, respectively, representing a mean increase of 68.7% _＋ 14.0% （P 〈 0.001）. Sixteen individuals （88.9%） were satisfied with the outcomes, and none were dissatisfied. There were no serious adverse events during the study. Cross-linked dextran gel injection for glans penis augmentation was easy and showed a significant augmentative effect on the glans penis, good durability, and was well tolerated without serious adverse events. Therefore, cross-linked dextran gel injection may be an effective, new technique for glans penis augmentation.

关键词： cosmetic technique dermal fillers dextran glans penis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

电极材料在铁磷酸盐玻璃熔体内腐蚀现象的研究

引用

稀有金属材料与工程 2006年第9期35卷 1424-1427页

作者：朱冬梅 Cheol-Woon kim Delbert E.Day 西北工业大学凝固技术国家重点实验室 Ceramic Engineering Department and Graduate Center for Materials Research University of Missouri-RollaRolla MO 65401USA

选用合金Inconel690和693作为研究对象,着重研究了它们在铁磷酸盐玻璃熔体中的腐蚀行为。分别计算了不同电极材料的尺寸损失和质量损失,以及相应的损失速率,采用SEM,EDS和XRD等手段对材料表面的腐蚀层进行了分析,确定了腐蚀层的成分,主... 详细信息

选用合金Inconel690和693作为研究对象,着重研究了它们在铁磷酸盐玻璃熔体中的腐蚀行为。分别计算了不同电极材料的尺寸损失和质量损失,以及相应的损失速率,采用SEM,EDS和XRD等手段对材料表面的腐蚀层进行了分析,确定了腐蚀层的成分,主要相组成及其晶粒形态,讨论了材料腐蚀发生的可能机理。结果表明,在玻璃熔体内,合金Inconel693比Inconel690更耐腐蚀。随着腐蚀时间的延长,合金的腐蚀速率都逐渐降低。合金试样表面的腐蚀层主要由固熔体(Fe,Cr)2O3组成。

关键词： Inconel合金腐蚀固熔体

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

基于最小二乘支持向量机算法的小地锚抗拔承载力研究（英文）

引用

Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2015年第4期16卷 295-301页

作者： Pijush SAMUI Dookie kim Bhairevi G.AIYER Centre for Disaster Mitigation and Management VIT University Department of Civil Engineering Kunsan National University School of Mechanical and Building Science VIT University

目的:基于最小二乘支持向量机算法预测小地锚的抗拔承载力。方法:最小二乘支持向量机算法中的输入参数包括等效地锚直径,地锚埋置深度,平均顶椎阻力,平均椎套摩擦力以及安装工艺。使用现场试验的119组数据中的83组数据进行最小二乘支持... 详细信息

目的:基于最小二乘支持向量机算法预测小地锚的抗拔承载力。方法:最小二乘支持向量机算法中的输入参数包括等效地锚直径,地锚埋置深度,平均顶椎阻力,平均椎套摩擦力以及安装工艺。使用现场试验的119组数据中的83组数据进行最小二乘支持向量机回归模型分析,并使用剩余的36组数据测试模型的拟合良好性;同时用敏感度分析研究每个输入参数的作用。结论:通过与人工神经网络模型的对比,发现最小二乘支持向量机的性能表现优异。

关键词：人工神经网络法最小二乘支持向量机误差条地锚抗拔承载力现场试验敏感度分析

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

PalmPhasor算法性能的理论分析

引用

软件学报 2015年第5期26卷 1237-1250页

作者：冷璐黎明 Andrew Beng Jin TEOH Cheonshik kim 无损检测技术教育部重点实验室(南昌航空大学) 江西南昌330063 School of Electrical and Electronic Engineering Yonsei University Department of Digital Media Engineering Anyang University

模板的安全性和隐私性是掌纹系统实际应用的关键问题,然而生物特征保护的多项指标通常相互冲突并且难以同时满足.作为解决上述冲突的一种可撤销掌纹编码算法,Palm Phasor实现了高效、安全的掌纹认证.建立了系统分析Palm Phasor性能的完... 详细信息

模板的安全性和隐私性是掌纹系统实际应用的关键问题,然而生物特征保护的多项指标通常相互冲突并且难以同时满足.作为解决上述冲突的一种可撤销掌纹编码算法,Palm Phasor实现了高效、安全的掌纹认证.建立了系统分析Palm Phasor性能的完整框架.为了便于具体分析,将情景分为4种情况,并且提供了支持相应分析的预备知识,包括辅助定理以及Gabor滤波掌纹图像实部和虚部分布特性.在统计学基础上建立的理论分析和实验结果均表明:即使在用户口令被盗的情况下,多方向分数级融合增强的Palm Phasor算法也可以同时有效地满足可撤销生物特征的4项指标.

关键词： Palm Phasor算法理论性能分析多方向分数级融合掌纹认证可撤销生物特征

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：