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New Concept for Calculating DC Harmonic Voltages and Currents in BTB HVDC Converters

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Journal of Power and Energy Engineering 2014年第11期2卷 33-42页

作者： Chan-Ki Kim seong-Doo Lee Soon-Ho choi Yong-Beum Yoon KEPCO KEPRI (Korea Electric Power Research Institute) Daejeon Korea

This paper deals with a new concept for calculating DC harmonic voltages and currents of line- commutated HVDC systems. In contrast to the conventional method, this method is useful for BTB (Back-To-Back) HVDC systems without smoothing reactors or PTP (Point-To-Point) with very short transmission line. This method proposes a new direction for HVDC system design and analysis. The proposed method is applied to a 50 Hz/60 Hz BTB test system and a synchronized BTB test system. After simulation and verification, the new results are introduced.

关键词： HVDC BTB (Back-To-Back) PTP (Point-To-Point)

Interaction of Immune System Protein with PEGylated and Un-PEGylated Polymeric Nanoparticles

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Advances in Nanoparticles 2017年第3期6卷 103-113页

作者： Matthewos Eshete Kayla Bailey Tuyen Duong Thanh Nguyen Santosh Aryal seong-O choi Department of Chemistry Mississippi Valley State University Itta Bena MS USA Nanotechnology Innovation Center of Kansas State (NICKS) Kansas State University Manhattan KS USA Department of Chemistry Kansas State University Manhattan KS USA Department of Anatomy and Physiology Kansas State University Manhattan KS USA

Biodegradable Nanoparticles (NPs) are under intense investigation due to their potential application in targeted drug delivery. Upon their entry to the biological system, they encounter the immune system, which limits their availability at the intended site. Most importantly, the innate immune system is the one that acts as the first line of defense against foreign materials. It can be activated by collectin proteins which recognize the structural pattern of polysaccharide on the surface of microorganisms. NPs may interact with these proteins in a similar way, and the interaction may lead to beneficial outcomes in vaccine delivery. On the other hand, in targeted drug delivery, it is desirable for the NPs not to be recognized as foreign material as this may lead to their fast elimination from the system through mechanism such as opsonization. We investigated the interaction of PEGylated and un-PEGylated PLGA NPs with Recombinant Human Mannose-Binding Protein (HMBP) in an effort to understand the effect of surface modification on their binding to the protein. Results show that both PLGA-COOH and PLGA-PEG-NH2 bind to HMBP as studied using dynamic light scattering (DLS), fluoresce and UV-vis spectroscopy. However, their binding is shown to have different effect on the structure of the protein. Study done using fluorescence spectroscopy displayed a decrease in fluorescence emission of the protein upon binding to PLGA-COOH. On the other hand the fluorescence emission of the protein increased upon binding to the PLGA-PEG-NH2 indicating conformational changes in the protein structure.

关键词： Nanoparticles Mannose-Binding Protein Poly (L-Lactic-Co-Glycolic Acid) Nanoparticle Protein Interaction

Comparison of outcomes between laparoscopicvs. open liver resection for intermediate stage hepatocellular carcinoma

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Hepatoma Research 2018年第1期4卷 13-20页

作者： Avril David YoungRok choi Ho-seong Han Yoo-Seok Yoon Jai Young Cho Department of Surgery Seoul National University College of MedicineSeoul National University Bundang HospitalSeongnam-siGyeonggi-do 13620South Korea Department of Surgery Rizal Medical CenterPasig City 1600Philippines

Aim: The Barcelona Clinic Liver Score (BCLC) currently limits hepatic resection only for small, solitary tumors measuring 2-3 cm with no signs of portal hypertension (PHT) or macrovascular invasion. The aim of this study was to show the benefit of surgical resection, and to compare the peri-operative and long-term outcomes between laparoscopic liver resection (LLR) and open liver resection (OLR) for hepatocellular carcinoma (HCC) classified as intermediate stage (B) under BCLC. Methods: From 2004 to 2013, 49 patients staged as intermediate (BCLC B) and who underwent hepatic resection was included. These patients were divided into LLR or OLR. Demographics, tumor characteristics, recurrence rates and overall survival (OS) were compared between the 2 groups. Results: Forty-nine patients were included and grouped into LLR (n = 28) and OLR (n = 21). The average tumor number was 2 ± 1 for both groups, while the mean tumor size was 4.4 ± 1.7 cm and 5.3 ± 2.6 cm for the LLR and OLR group, respectively. When compared with OLR, LLR had lower post-operative complications (14.3% vs. 33.3%, P = 0.114), and a statistically significant shorter hospital stay than the OLR group (9 vs. 21 days, P = 0.023). The LLR group also achieved a statistically significant difference in complete R0 resection as compared with the OLR group (P =0.016). The OS and disease-free survival (DFS) at 1, 3 and 5 years were comparable between LLR and OLR (OS: 89.1% vs. 76.2%;70.4% vs. 55.9%;58.6% vs. 43.5%, P = 0.583;DFS: 59.3% vs. 51.0%;20.2% vs. 44.6%;16.2% vs. 37.2%, P = 0.947, respectively). Conclusion: LLR showed comparable outcomes compared to OLR in the treatment of HCC staged BCLC B. Therefore, LLR as well as OLR can be considered in selective patients in the BCLC B group.

关键词： Hepatocellular carcinoma minimally invasive surgical procedures laparoscopy

Environment-friendly Control of Soil Born Disease Using High Temperature Steam-Sterilizer in Plastic house

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Environment-friendly Control of Soil Born Disease Using High...

Detection of Virus and Infection Pattern on Garlic（Allium scordorpasum ***） in Korea

中国植物病理学会2012年学术年会

作者： choi seong-Yong Lee Joong-Hwan Park Sang-Gu Department of Agricultural Environment Gyeongsangbuk-do Agricultural Research and Extension ServicesDaegu702-708Republic of Korea Institute for Bioresources Research Gyeongsangbuk-do Agricultural Research and Extension ServicesAndong760-891Republic of Korea

＜正＞Soil born disease including root knot nematodes（Meloidogyne spp.） caused severe economic loss in Plastic *** experiment was carried out to control these disease using High Temperature *** temperature steam（HTS） was pumped up into the under-ground（depth 50cm） through pored plastic pipe（diameter 10cm） in plastic *** temperature was reached over 80t after one hour treatment with *** density of microorganism in the soil including fungi,actinomycetes and bacteria was significantly decreased by HTS treatment compared to non-treated *** HTS treatment,the average population of root knot nematodes was significantly reduced from 1 570 heads to 0（Head/300g soil）.The withering rates of oriental melon by root knot nematodes was 5.2%in HTS and 10.4%in chemical fumigation（dazomet） treatment but 60.2%was withered in control in middle stage of growth at 150 days after *** effect of HTS treatment was as effective as dazomet fumigation ***,we concluded that HTS can be used as an environment-friendly control method,alternate to chemical fumigation for the control of Soil born disease in plastic house.

关键词： Soil born disease High Temperature Steam-Sterilizer Root knot nematodes

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Detection of Virus and Infection Pattern on Garlic（Allium s...

A Web-based on-machine mould matching and measurement system based on CAD/CAM/CAI integration

中国植物病理学会2011年学术年会

作者： Joong-Hwan Lee seong-Yong choi Hong-Sik Shim Department of Agricultral Environment Gyeongsangbuk-do Agricultural Research and ExtentionDongho-dongDaegu702-708Republic of Korea Crop Protection Division National Academy of Agricultural ScienceRDASuwon 441-707Republic of Korea

＜正＞In Korea,garlic is major vegetable crop and it is grown on 26323 ha in *** diseases spreaded throughout the world and cause serious damage on *** occurrence of virus diseases were surveyed from 2007 to 2010 and detected species of virus on leaves and *** related to infection by viruses appeared on some leaves in February at the time when garlic *** of garlic plant leaves（90.7%） in April and all of the garlic plant leaves were infected by one or more virus in *** infection rate of Allexivirus was the highest and followed by Shallot latent virus（SLV）,Onion yellow dwarf

关键词： Garlic Shallot latent virus(SLV) Onion yellow dwarf virus(OYDV ) Garlic common latent virus(GCLV) and Leek yellow stripe virus(LYSV) Virus infection rate

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2006年第9期7卷 1474-1481页

作者： choi Jin-hwa JEON Byung-cheol KIM Gun-hee SHIN Bong-cheol LEE Honghee CHO Myeong-woo seong Eun-je PARK Dong-sam Division of Mechanical Engineering Inha University Incheon 402-751 Korea Department of Mechanical Engineering University of Incheon Incheon 402-749 Korea

The purpose of this study is to develop a Web-based on-machine mould identification and measurement system. The Web-based mould identification system matches obtained vision information with CAD database. Developed Web-based system is to exchange messages between a server and a client by making of ActiveX control, and the result of mould identification is shown on Web-browser at remote site. For effective feature classification and extraction, the signature method is used to make meaningful information from obtained image data. For on-machine measurement of the matched mould, inspection database is constructed from CAD database using developed inspection planning methods. The results are simulated and analyzed using developed system to verify the effectiveness of the proposed methods.

关键词： CAD CAM CAI 网络制造视觉系统

A GREENHOUSE ASSAY FOR IDENTIFICATION OF DURABLE BLAST RESISTANCE IN KOREAN RICE CULTIVARS

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A GREENHOUSE ASSAY FOR IDENTIFICATION OF DURABLE BLAST RESIS...

Repeat hepatic resection in patients with colorectal liver metastases

The ⅩⅤth International Plant Protection Congress

作者： seong Sook HAN Sang Won AHN Yeon Kyu HONG Jae Hwan ROH seong Ho choi Crop Environment and Biotechnology Div.National Crop Experiment Station RDA Suwon 441-100 Korea Crop Environment and Biotechnology Div.National Crop Experiment Station RDA Suwon 441-100 Korea National Yeongnam Agricultural Experiment Station RDA Milyang 627-803 Korea Crop Environment and Biotechnology Div.National Crop Experiment Station RDA Suwon 441-100 Korea Crop Environment and Biotechnology Div.National Crop Experiment Station RDA Suwon 441-100 Korea

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World Journal of Gastroenterology 2015年第7期21卷 2124-2130页

作者： Huisong Lee seong Ho choi Yong Beom Cho seong Hyeon Yun Hee Cheol Kim Woo Yong Lee Jin Seok Heo Dong Wook choi Kyung Uk Jung Ho-Kyung Chun Department of Surgery Samsung Medical Center Sungkyunkwan University School of Medicine Department of Surgery Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine

AIM:To investigate the survival outcomes of secondaryhepatectomy for recurrent colorectal liver metastases(CRLM).METHODS:From October 1994 to December 2009,patients with CRLM who underwent surgical treatment with curative intent were *** were divided into two groups:patients who underwent primary hepatectomy(Group 1)and those who underwent secondary hepatectomy for recurrent CRLM(Group 2).RESULTS:Survival and prognostic factors were analyzed.A total of 461 patients were included:406patients in Group 1 and 55 patients in Group *** a median 39-mo(range,3-195 mo)follow-up,there was a significant difference between Groups 1 and 2in terms of disease-free survival(P=0.029)although there was no significant difference in overall survival(P=0.206).Secondary hepatectomy was less effective in patients with multiple recurrent CRLM than primary hepatectomy for initial CRLM(P=0.008).Multiple CRLM and radiofrequency ablation therapy were poor prognostic factors of secondary hepatectomy in multivariate Cox regression analysis(P=0.006,P=0.004,respectively).CONCLUSION:Secondary hepatectomy for single recurrent CRLM is as effective as primary surgical treatment for single recurrent ***,secondary hepatectomy for multiple recurrent CRLM is less effective than that for single recurrent CRLM.

关键词： Colorectal neoplasm Metastasis Recurrence Hepatect

基于转录组测序的油酸诱导延边牛骨骼肌卫星细胞成脂分化差异表达基因的分析

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动物营养学报 2021年第4期33卷 2263-2277页

作者：孙建富孙斌张军芳王英崔岩李强 choi seong H SHIN Jong S 李香子延边大学东北寒区肉牛科技创新教育部工程研究中心延吉133002 韩国忠北国立大学动物生命科学学院清州361-763 韩国江原国立大学校动物生命科学学院春川200-701

本研究旨在研究油酸(OA)引起延边牛骨骼肌卫星细胞成脂分化途径的分子调控机制。对从12日龄延边牛中分离得到的骨骼肌卫星细胞进行体外培养,加入不同浓度OA的诱导分化培养液,进行分化处理,试验设1个空白对照组[CON组,5%马血清(HS)],3个... 详细信息

本研究旨在研究油酸(OA)引起延边牛骨骼肌卫星细胞成脂分化途径的分子调控机制。对从12日龄延边牛中分离得到的骨骼肌卫星细胞进行体外培养,加入不同浓度OA的诱导分化培养液,进行分化处理,试验设1个空白对照组[CON组,5%马血清(HS)],3个不同浓度OA诱导组:OAL组(5%HS+50μmol/L OA)、OAM组(5%HS+100μmol/L OA)、OAH组(5%HS+200μmol/L OA),诱导96 h后,对延边牛骨骼肌卫星细胞进行了转录组测序及分析。结果表明:共得到13951条单基因,对4个组差异表达基因进行比较发现,与CON组相比,OAL组有3412个差异表达基因,OAM组有1045个差异表达基因,OAH组有1428个差异表达基因,各组之间共有278个差异表达基因。GO富集分析显示,差异基因参与了多种生物过程,包括代谢过程、细胞过程、生物调节过程等;在分子功能类别上,大多数的基因功能与结合活性、转录调节活性、催化活性等相关;在细胞组分范畴内,大部分的基因被富集到细胞、细胞器、膜等。KEGG富集分析表明,差异表达基因主要富集通路为单磷酸腺苷激活的蛋白激酶(AMPK)信号通路、过氧化物酶体增殖物激活受体(PPAR)信号通路、脂肪酸代谢通路、脂肪酸降解通路等。不同浓度OA差异基因荧光定量PCR结果显示,所选的5个差异基因与转录组测序结果基本一致,表明了测序结果的可靠性。本试验完成了OA诱导延边牛骨骼肌卫星细胞成脂分化的转录组测序分析,获取差异基因的功能注释信息,初步揭示了OA诱导牛骨骼肌卫星细胞成脂分化的潜在基因和通路。

关键词：转录组测序油酸延边牛骨骼肌卫星细胞成脂分化