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Co-doping Effect on Microstructures and Ionic Conductivity of Aliovalent Cations Modified Ceria

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材料科学与工程学报 2007年第6期25卷 861-863页

作者： yeh Tsung-her CHOU Chen-chia Advanced Ceramics Laboratory Department of Mechanical EngineeringNational Taiwan University of Science and TechnologyTaipei-10672China

Microstructural features and ionic conductivity of divalent(Mg 2+)and trivalent(Gd 3+)cations co-doped ceria electrolyte system Ce_ 0.8-xGd_ 0.2Mg_xO_ 1.9-x were investigated by scanning electron microscopy(SEM)and AC impedance *** experimental results exhibit that addition of MgO to GDC reduces the average binding energy of GDC by decreasing the energy barrier of oxygen ion migration in ceria matrix and the ionic conductivity of 2 mol% magnesium doped GDC(0.018 S/cm)is higher than that of GDC matrix at 650℃(0.0105 S/cm).Co-doping Mg 2+ and Gd 3+ is found to increase the ionic conductivity of ceria and hence decreases the operation temperature as well as the cost of solid oxide fuel cell(SOFC).

关键词：钴掺杂离子电导性改良铈固体氧化物燃料电池结合能电解质

Innovations in the diagnosis and management of uveitis: promising research to address unmet patient needs

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Annals of Eye Science 2022年第1期7卷 1-7页

作者： Steven yeh Ye Huang Joanne Thomas Truhlsen Eye Institute University of Nebraska Medical CenterOmahaNEUSA Emory Eye Center Emory University School of MedicineAtlantaGAUSA Medical College of Georgia AugustaGAUSA.

Uveitis,or inflammation of the uveal tissues(iris,ciliary body and the choroid),and its contiguous structures,can lead to severe visual impairment and is among the leading causes of vision impairment worldwide(1).In clinical practice,specialists in uveitis and ocular immunology are called upon to manage a range of uveitis syndromes-infectious disease,noninfectious autoimmune conditions,and masquerade syndromes such as ***,ophthalmologists of all subspecialties(i.e.,medical and surgical retina,corneal surgeons,orbital/oculoplastic surgeons,and comprehensive ophthalmologists)are called upon to manage uveitis syndromes,emphasizing clear importance to understanding common uveitis syndromes,diagnostic workups,and the state-of-the-art in uveitis and ocular inflammation care.

关键词： uveitis inflammation diagnosis

Blood micronutrient, oxidative stress, and viral load in patients with chronic hepatitis C

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World Journal of Gastroenterology 2005年第30期11卷 4697-4702页

作者： Wang-Sheng Ko Chih-Hung Guo Maw-Sheng yeh Li-yun Lin Guoo-Shyng W. Hsu Pei-Chung Chen Mei-Ching Luo Chia-yeh Lin Department of Food and Nutrition Hung Kuang University Department of Internal Medicine Kuang-Tien General Hospital Taichung 433 Taiwan China Department of Food and Nutrition Hung Kuang University Taichung 433 Taiwan China Department of Nutrition and Food Sciences Fu Jen University Taipei 242 Taiwan China Department of Biotechnology Hung Kuang University Taichung 433 Taiwan China

AIM: To assess the extent of micronutrient and oxidative stress in blood and to examine their linkages with viral loads in chronic hepatitis C ***: Hepatitis C virus (HCV)-RNA levels were quantified in the serum from 37 previously untreated patients with chronic hepatitis C. The plasma and erythrocyte micronutrients (zinc, selenium, copper, and iron) were estimated, and malondialdehyde (MDA)contents were determined as a marker to detect oxidative stress. Antioxidant enzymes, superoxide dismutase (SOD),glutathione peroxidase (GPX) and glutathione reductase (GR) activities in blood were also measured. The control group contained 31 healthy ***: The contents of zinc (Zn), and selenium (Se)in plasma and erythrocytes were significantly lower in hepatitis C patients than in the controls. On the contrary,copper (Cu) levels were significantly higher. Furthermore,plasma and erythrocyte MDA levels, and the SOD and GR activities in erythrocytes significantly increased in hepatitis C patients compared to the controls. However, the plasma GPX activity in patients was markedly lower. Plasma Se (r= -0.730, P<0.05), Cu (r = 0.635), and GPX (r = -0.675)demonstrated correlations with HCV-RNA loads. Significant correlation coefficients were also observed between HCV-RNA levels and erythrocyte Zn (r = -0.403), Se (r = -0.544), Cu (r = 0.701) and MDA (r = 0.629) and GR (r = 0.441).CONCLUSION: The levels of Zn, Se, Cu, and oxidative stress (MDA), as well as related anti-oxidative enzymes (GR and GPX) in blood have important impact on the viral factors in chronic hepatitis C. The distribution of these parameters might be significant biomarkers for HCV.

关键词： Micronutrient Oxidative stress Viral load Plasma and erythrocytes Hepatitis C

Primary squamous cell carcinoma of the liver:A successful surgically treated case

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World Journal of Gastroenterology 2006年第33期12卷 5419-5421页

作者： Hsiang-Lin Lee Yu-Yin Liu Chun-Nan yeh kun-Chun Chiang Tse-Ching Chen Yi-Yin Jan Department of Surgery Chang Gung Memorial Hospital Chang Gung University Taiwan China Department of Pathology Chang Gung Memorial Hospital Chang Gung University Taiwan China

Primary squamous cell carcinoma (SCC) of the liveris rare. Totally nine such cases have been reportedin the literature. Primary SCC of the liver has beenreported to be associated with hepatic teratoma,hepatic cyst, or hepatolithiasis. Complete remission ofpoorly differentiated SCC of the liver could be achievedby systemic chemotherapy followed by surgery orremarkably respond to hepatic arterial injection of lowdose chemotherapeutic drugs. Here we report the fi rstcase of primary SCC of the liver presenting as a solidtumor and receiving successful hepatic resection with9-mo disease free survival.

关键词： Squamous cell carcinoma Liver Surgery

Discovering optimal weights in weighted‑scoring stock‑picking models: a mixture design approach

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Financial Innovation 2020年第1期6卷 814-841页

Certain literature that constructs a multifactor stock selection model adopted a weighted-scoring approach despite its three ***,it cannot effectively identify the connection between the weights of stock-picking concepts and portfolio ***,it cannot provide stock-picking concepts’optimal combination of ***,it cannot meet various investor ***,this study employs a mixture experimental design to determine the weights of stock-picking concepts,collect portfolio performance data,and construct performance prediction models based on the weights of stock-picking ***,these performance prediction models and optimization techniques are employed to discover stock-picking concepts’optimal combination of weights that meet investor *** samples consist of stocks listed on the Taiwan stock *** modeling and testing periods were 1997–2008 and 2009–2015,*** evidence showed(1)that our methodology is robust in predicting performance accurately,(2)that it can identify significant interactions between stock-picking concepts’weights,and(3)that which their optimal combination should *** combination of weights can form stock portfolios with the best performances that can meet investor ***,our methodology can fill the three drawbacks of the classical weighted-scoring approach.

关键词： Portfolio optimization Stock-picking Weighted-scoring Mixture experimental design Multivariable polynomial regression analysis

O-glycosylation in liver cancer:Clinical associations and potential mechanisms

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Liver Research 2017年第4期1卷 193-196页

作者： kung-Hao Liang Chau-Ting yeh Liver Research Center Chang Gung Memorial HospitalTaoyuanTaipeiChina Medical Research Department Taipei Veterans General HospitalTaipeiChina Molecular Medicine Research Center Chang Gung UniversityTaoyuanTaipeiChina

Liver cancer can be an aggressive disease,and is highly prevalent in Asia and ***,its currently approved therapeutic strategies are far from *** progress in genomic,proteomic and glycomic profiling technologies have enabled the identification of biomarkers that significantly correlate with clinical *** biomarkers are related to O-glycosylation of glycoproteins,which belong to an important but less-explored field of liver cancer ***,we review these clinical studies and discuss potential underlying mechanisms.

关键词： O-glycosylation Post-translational modification Glycobiology Biomarkers Hepatocellular carcinoma(HCC) Glycosyltransferase

OPTIMAL MAINTENANCE AND REPLACEMENT OF EXTRACTION MACHINERY

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Journal of Systems Science and Systems Engineering 2008年第4期17卷 416-431页

作者： Suresh P. SETHI Hong-Mo yeh Rong ZHANG Andrew K.S. JARDINE School of Management the University of Texas at Dallas USA Department of Information Management Fu Jen Catholic University Taiwan China College of Economics and Business Administration Chongqing University Chongqing China Department of Mechanical and lndustrial Engineering University of Toronto Canada

This paper considers a problem of optimal preventive maintenance and replacement schedule of equipment devoted to extracting resources from known deposits. Typical examples are oil drills, mine shovels, etc. At most one replacement of the existing machinery by a new one is allowed. The problem is formulated as an optimal control problem subject to the state constraint that the remaining deposit at any given time is nonnegative. We show that the optimal preventive maintenance, production rates, and the replacement and salvage times of the existing machinery and the new one, if required, can be obtained by solving sequentially a series of free-end-point optimal control problems. Moreover, an algorithm based on this result is developed and used to solve two illustrative examples.

关键词： Maintenance and replacement optimal control the maximum principle extraction machinery exhaustible resource

Multifocal intraductal papillary mucinous neoplasm of the pancreas-A case report

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World Journal of Gastroenterology 2009年第5期15卷 628-632页

作者： kun-Chun Chiang Jun Te Hsu Shyh Chuan Jwo Tsann-Long Hwang Yi-Yin Jan Chun-Nan yeh Department of Surgery Chang Gung Memorial Hospital Chang Gung University 5 Fu-Hsing Street Kwei-Shan Taoyuan Taiwan 333 China

Cystic neoplasms of the pancreas are relatively rare, comprising 10 percent of pancreatic cysts and only 1 percent of pancreatic cancers. Cystic neoplasms include mucinous cystic neoplasms, serous cystadenomas, papillary cystic tumors, cystic islet cell tumors and intraductal papillary mucinous neoplasms of the pancreas (IPMNs). IPMN was first described in 1982. It has been most commonly described in 60 to 70 years old males, and represents a relatively ''new'' but increasingly recognized disease. The improvement and widespread use of modern imaging equipments and heightened awareness of physicians contribute to the increasing incidence of IPMN. The majority of IPMNs are located in the pancreatic head (75%) while the rest involves the body/tail regions. Multifocal IPMNs have been hypothesized, but the true presence of multifocality is unknown. Here we present a 72-yearold male diagnosed with IPMN (carcinoma in situ ) in the pancreatic head and a branch duct type IPMN (duct atypia) in the pancreatic body and tail. The patient underwent a Whipple intervention and a distal pancreatectomy. A three-year disease-free survival has been observed so far.

关键词： Intraductal papillary mucinous neoplasm Pancreas Multifocal Pancreatectomy Intraductalpapillary mucinous neoplasms

Efficient and secure three-party authenticated key exchange protocol for mobile environments

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Journal of Zhejiang University-Science C(Computers and Electronics) 2013年第5期14卷 347-355页

作者： Chih-ho CHOU Kuo-yu TSAI Tzong-chen WU Kuo-hui yeh Department of Information Management National Taiwan University of Science and Technology Department of Management Information Systems Hwa Hsia Institute of Technology Department of Information Management National Dong Hwa University

Yang and Chang (2009) proposed a three-party authenticated key exchange protocol for securing communications in mobile-commerce environments. Their protocol reduces computation and communication costs by employing elliptic curve cryptosystems. However, Tan (2010) pointed out that Yang and Chang (2009)'s protocol cannot withstand impersonation and parallel attacks, and further proposed an enhanced protocol to resist these attacks. This paper demonstrates that Tan (2010)'s approach still suffers from impersonation attacks, and presents an efficient and secure three-party authenticated key exchange protocol to overcome shown weaknesses.

关键词： Three-party Key exchange Authentication Mobile environments