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Exploring the transformative impact of traditional Chinese medicine on depression:Insights from animal models

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World Journal of Psychiatry 2024年第5期14卷 607-623页

作者： yan yang yan-kun Chen Meng-Zhou Xie School of Nursing Hunan University of Chinese MedicineChangsha 410200Hunan ProvinceChina Precision Medicine R&D Center Zhuhai Institute of Advanced TechnologyChinese Academy of SciencesZhuhai 519000Guangdong ProvinceChina School of Chinese Medicine Hunan University of Chinese MedicineChangsha 410200Hunan ProvinceChina Hunan Engineering Technology Research Center for Medicinal and Functional Food Hunan University of Chinese MedicineChangsha 410200Hunan ProvinceChina Key Laboratory of TCM Heart and Lung Syndrome Differentiation and Medicated Diet and Dietotherapy Hunan University of Chinese MedicineChangsha 410200Hunan ProvinceChina

Depression,a prevalent and complex mental health condition,presents a significant global health *** is one of the most frequent mental disorders;deaths from it account for 14.3%of people *** recent years,the integration of complementary and alternative medicine,including traditional Chinese medicine(TCM),has gained attention as a potential avenue for addressing *** comprehensive review critically assesses the efficacy of TCM interventions in alleviating depressive *** in-depth look at different research studies,clinical trials,and meta-analyses is used in this review to look into how TCM practices like herbal formulations,acupuncture,and mindbody practices *** review looks at the quality of the evidence,the rigor of the methods,and any possible flaws in the current *** gives us an idea of where TCM stands right now in terms of treating *** comprehensive review aims to assess the efficacy of TCM interventions in alleviating depressive *** order to learn more about their possible healing effects,the study also looks into how different types of TCM work,such as herbal formulas,acupuncture,and mind-body practices.

关键词： Traditional Chinese medicine Depression Efficacy Treatment Holistic approach

A scalable versatile methodology to construct micro/nano open-cell polypropylene foam with high oil adsorption capacity and speed

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Nano Research 2024年第4期17卷 2814-2823页

作者： Chenguang yang Dechang Tao kun yan Zhiyao Li Qingshi Guo Wenwen Wang Dong Wang Key Laboratory of Textile Fiber and Products(Wuhan Textile University) Ministry of EducationWuhan Textile UniversityWuhan 430200China College of Chemistry Chemical Engineering and BiotechnologyDonghua UniversityShanghai 201620China

Oil pollution is a serious environmental and natural resource *** adsorption materials for oil–water separation have limitations in terms of their preparation cost,reusability,and mechanical *** the conventional adsorption materials,super-hydrophobic/super-lipophilic materials are easily contaminated by *** this study,polypropylene(PP)is used as a foam substrate to prepare an open-cell PP foam via hot pressing,supercritical CO_(2) foaming,and electron beam(EB)*** impact of EB irradiation dose on the open-cell content of PP foam can lead to cell wall rupture,resulting in an open-cell structure that enhances oil-water separation *** an absorbed radiation dose of 200 kGy,the PP foams exhibit optimal oil–water separation performance,cyclic compression stability,heat insulation,and preparation *** open-cell content of PP foam is increased to 86.5%,the adsorption capacity for diesel oil is 42.8 g/g,and the adsorption efficiency remains at 99.6%after 100 cycles of oil desorption in a complex pH ***,cracks and nano-voids simultaneously promote the capillary action of oil,and the oil transport rate is 0.0713 g/(g·s).This study provides a new concept for the preparation of open-cell polymer foams that can meet the demand for high oil-absorption capacity under complex acid-base pH conditions.

关键词： open-cell polypropylene(PP)foam electron beam irradiation oil/water separation cyclic compression complex acid-base pH conditions

Structure regulating of metal clusters in carbonized metallic organic frameworks for high-efficient microwave absorption via tuning interaction strength between metals and ligands

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Nano Research 2024年第3期17卷 1699-1709页

作者： Chang Sun kun-yan Zhao Ming-Lu Huang Cheng-Long Luo Xu-Dong Chen Ming Wang School of Chemistry and Chemical Engineering Chongqing Key Laboratory of Soft-Matter Material Chemistry and Function ManufacturingSouthwest UniversityChongqing 400715China Jieyang Branch of Chemistry and Chemical Engineering Guangdong Laboratory(Rongjiang Laboratory) Jieyang 515200China

Carbonized metallic organic frameworks(CMOF)have been attracting attention in microwave absorption(MA)research area because of their diverse structures,tunable compositions,and rich ***,structure regulation on metal clusters in CMOF is achieved by tuning the interaction strength between metals and ligands to enhance microwave absorption *** to relatively weak interaction among copper cations and ligands,copper nanoclusters(CuNC)can be uniformly formed and embedded within the cobalt/zinc(Co/Zn)***,copper cations are added to the Co/Zn bimetallic zeolitic imidazolate frameworks(ZIFs).Secondly,the CMOF composite particles with CuNCs(CuNCs/CoZn-CMOF)were developed by a pyrolysis *** CuNCs/CoZn-CMOF with an appropriate amount of CuNCs can harmonize both dielectric and magnetic *** a result,the minimum reflection loss(RLmin)reaches–45.1 dB at a matching thickness of 2.30 mm and the effective absorption bandwidth(EAB)is 8.80 GHz at a thickness of 3.10 *** broadband response to electromagnetic waves is attributed to interfacial polarization at CuNCs surface and heterogeneous interfaces,impedance matching and multiple scattering of electromagnetic *** study provides a feasible method to develop CMOF microwave absorption materials with high EAB values.

关键词： heterogeneous interface carbonized metallic organic frameworks microwave absorption interfacial polarization

Low-density lipoprotein receptor-related protein 2(LRP2)is required for lipid export in the midgut of the migratory locust,Locusta migratoria

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Journal of Integrative Agriculture 2024年第5期23卷 1618-1633页

作者： Yiyan Zhao Weimin Liu Xiaoming Zhao Zhitao Yu Hongfang Guo yang yang Hans Merzendorfer kun yan Zhu Jianzhen Zhang Research Institute of Applied Biology Shanxi Key Laboratory of Nucleic Acid BiopesticidesShanxi UniversityTaiyuan 030006China College of Life Science Shanxi UniversityTaiyuan 030006China Interfaculty Institute of Cell Biology University of TubingenTubingen 72076Germany Institute of Biology University of SiegenSiegen 57076Germany Department of Entomology Kansas State UniversityManhattanKS 66506USA

Low-density lipoprotein receptor-related protein 2(LRP2)is a multifunctional endocytic receptor expressed in epithelial *** mammals,it acts as an endocytic receptor that mediates the cellular uptake of cholesterol-containing apolipoproteins to maintain lipid ***,little is known about the role of LRP2 in lipid homeostasis in *** the present study,we investigated the function of LRP2 in the migratory locust Locusta migratoria(LmLRP2).The mRNA of LmLRP2 is widely distributed in various tissues,including integument,wing pads,foregut,midgut,hindgut,Malpighian tubules and fat body,and the amounts of LmLRP2 transcripts decreased gradually in the early stages and then increased in the late stages before ecdysis during the nymphal developmental *** immunohistochemistry revealed that the LmLRP2 protein is mainly located in cellular membranes of the midgut and *** RNAi to silence LmLRP2 caused molting defects in nymphs(more than 60%),and the neutral lipid was found to accumulate in the midgut and surface of the integument,but not in the fat body,of dsLmLRP2-treated *** results of a lipidomics analysis showed that the main components of lipids(diglyceride and triglyceride)were significantly increased in the midgut,but decreased in the fat body and ***,the content of total triglyceride was significantly increased in the midgut,but markedly decreased in the fat body and hemolymph in dsLmLRP2-injected *** results indicate that LmLRP2 is located in the cellular membranes of midgut cells,and is required for lipid export from the midgut to the hemolymphand fat body in locusts.

关键词： Locusta migratoria low-density lipoprotein receptor-related protein 2 midgut lipids transport RNAi

Prevalence of hypertension and its associations with body composition across Chinese and American children and adolescents

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World Journal of Pediatrics 2024年第4期20卷 392-403页

作者： Li-Wang Gao Yi-Wen Huang Hong Cheng Xi Wang Hong-Bo Dong Pei Xiao Yin-kun yan Xin-Ying Shan Xiao-Yuan Zhao Jie Mi Center for Non-Communicable Disease Management Beijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthNo.56 Nanlishi RoadXicheng DistrictBeijing100045China Department of Epidemiology Capital Institute of PediatricsNo.2 Yabao RoadChaoyang DistrictBeijing100020China Key Laboratory of Major Diseases in Children Ministry of EducationBeijingChina

Background The age of onset of hypertension(HTN)is decreasing,and obesity is a significant risk *** prevalence and racial disparities in pediatric HTN and the association between body composition and blood pressure are insufficiently *** study aimed to evaluate the prevalence of HTN in Chinese and American children and adolescents and to assess the relationship between various body composition indices and *** Seven thousand,five hundred and seventy-three Chinese and 6239 American children and adolescents aged 8–18 years from the 2013–2015 China Child and Adolescent Cardiovascular Health study and the 2011–2018 National Health and Nutrition Examination Surveys were *** pressure and body composition(fat and muscle)were measured by trained *** crude prevalence and age-standardized prevalence rate(ASPR)of primary HTN and its subtypes[isolated systolic hypertension(ISH)and isolated diastolic hypertension(IDH)]were calculated based on 2017 American Academy of Pediatrics ***-adjusted linear regression coefficients and odds ratios(ORs)were calculated to assess the associations of body composition indicators with HTN,ISH and *** The ASPR of HTN was 18.5%in China(CN)and 4.6%in the United States(US),whereas the obesity prevalence was 7.4%and 18.6%,and the population attributable risk of HTN caused by overweight and obesity was higher in the US than in *** fat mass,muscle mass and body fat percentage mass were associated with a higher risk of HTN in both *** percent of muscle body mass had a protective effect on HTN and ISH in both countries[HTN(CN:OR=0.83,95%CI=0.78–0.88;US:OR=0.72,95%CI=0.64–0.81);ISH(CN:OR=0.87,95%CI=0.80–0.94;US:OR=0.71,95%CI=0.62–0.81)],and the protective effect was more common among children and adolescents with high levels of physical *** The burden of HTN in Chinese children and adolescents was substantial and much greater than that in the US,and th

关键词： Body composition Children and adolescents China Child and Adolescent Cardiovascular Health Hypertension National Health and Nutrition Examination Surveys

中国拔尖人才教育政策嬗变研究——基于1977—2022年政策文本的分析

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中国高教研究 2024年第1期 41-49页

作者：吴菡阎琨北京教育科学研究院高等教育研究所北京100036 清华大学教育研究院北京100084

政策作为拔尖人才教育的环境要素,对拔尖人才培养具有支撑作用。以1977—2022年的144份政策文本为分析对象,将我国拔尖人才教育政策的历史演进划分为探索和起步、渐进扩展、反思更迭和理性创新4个阶段,采用政策文献量化分析方法,从基本... 详细信息

政策作为拔尖人才教育的环境要素,对拔尖人才培养具有支撑作用。以1977—2022年的144份政策文本为分析对象,将我国拔尖人才教育政策的历史演进划分为探索和起步、渐进扩展、反思更迭和理性创新4个阶段,采用政策文献量化分析方法,从基本事实和价值两个层面探究我国拔尖人才教育政策的演进脉络和方向。基于研究结果,建议着力提升对拔尖人才教育的政策关注度,构建多主体协同参与的拔尖人才教育格局,加强对我国拔尖人才教育本土化经验的研究,凝练具有中国特色的方案和模式,并厘清拔尖人才教育政策的定位,强化政策协同。

关键词：拔尖人才教育政策政策变迁内容分析量化分析

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数智时代科技伦理教育改革的思考

自然辩证法研究 2024年第3期40卷 132-137页

作者：闫坤如华南师范大学哲学与社会发展学院广州510631

科学技术的发展带来伦理问题,引发认识论革命、方法论革命以及教学方式变革,科技发展也带来科学伦理教育教学内容的变革,教育科学技术的发展已经从网络时代、信息时代来到数智时代,我们通过分析数智时代科技伦理教育的新特征,尝试从学... 详细信息

科学技术的发展带来伦理问题,引发认识论革命、方法论革命以及教学方式变革,科技发展也带来科学伦理教育教学内容的变革,教育科学技术的发展已经从网络时代、信息时代来到数智时代,我们通过分析数智时代科技伦理教育的新特征,尝试从学科定位、课程设置、教育对象、数智赋能等方面给出数智时代科技伦理教育路径,从而推动我国科技伦理教育的个性化、终身化、智慧化发展。

关键词：科技伦理科技伦理教育教育革命数智赋能

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轻量化YOLO-v7的数显仪表检测及读数

计算机工程与应用 2024年第8期60卷 192-201页

作者：章芮宁闫坤叶进桂林电子科技大学广西桂林541004 广西大学南宁530004

由于较大的参数体量和较高的计算复杂度,通用检测及识别模型直接在移动端部署的难度较高。为解决这个困难,研究了移动设备上使用计算机视觉的仪表检测及读数方法。针对实际工业生产环境下检测及识别的需求,基于YOLO-v7重新设计了轻量化... 详细信息

由于较大的参数体量和较高的计算复杂度,通用检测及识别模型直接在移动端部署的难度较高。为解决这个困难,研究了移动设备上使用计算机视觉的仪表检测及读数方法。针对实际工业生产环境下检测及识别的需求,基于YOLO-v7重新设计了轻量化的仪表检测网络以及字符检测及识别网络。利用深度可分离卷积进一步降低计算复杂度,压缩模型大小。采用K-means++聚类算法加遗传算法自动产生初始锚框。使用通道剪枝,再一次压缩模型。实验结果证明,专用网络模型设计、深度可分离卷积以及通道剪枝对减少模型参数体量和降低算力需求具有显著效果。参数数量相较于原始YOLO-v7模型均下降了99.67%,模型算力需求均降至0.3 GFLOPs,下降了99.71%。实验中平均图片检测时间为10.7 ms。各网络的平均精准度(mAP0.5)达到了99.63%和99.53%。系统整体读数精确度达98.44%。

关键词：数显仪表 YOLO-v7 深度可分离卷积模型压缩通道剪枝

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国际高等教育数字化变革模式及其对我国数字化拔尖人才培养的启示

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教育发展研究 2024年第3期44卷 1-10页

作者：阎琨段梦涵清华大学教育研究院北京100084

伴随国际高等教育数字化改革潮流,我国也将高等教育数字化提升至国家战略高度。本研究基于“政府-院校-社会”三角驱动模型,将国际高等教育数字化变革分为四类模式:均衡驱动模式、社会导向的混合驱动模式、政府与院校导向的混合驱动模... 详细信息

伴随国际高等教育数字化改革潮流,我国也将高等教育数字化提升至国家战略高度。本研究基于“政府-院校-社会”三角驱动模型,将国际高等教育数字化变革分为四类模式:均衡驱动模式、社会导向的混合驱动模式、政府与院校导向的混合驱动模式、政府驱动的单轨模式。论文重点分析了美国、英国、法国、德国、俄罗斯、日本、印度、中国8个国家在四类高等教育数字化变革模式方面的具体特征,进而对高等教育数字化四类模式以及各国在数字化变革的制度、技术平台、资金、教学、科研、管理上呈现的差异特征进行评价。基于国际高等教育数字化变革模式的研究,本文为我国数字化拔尖人才培养提供如下三点启示:立足中国国情,借鉴国际前沿模型构建产科教支撑的复合型数字化人才培养内涵;以立足特色、兼具均衡的高等教育数字化模式驱动复合型数字化拔尖人才培养改革;基于内外协作、多元创新探索优化复合型数字化拔尖人才培养的实践路径。

关键词：高等教育数字化国际比较数字化变革人才培养战略