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Epidemiological and histopathological characteristics of thyroid carcinoma in a Tunisian health care center

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第1期10卷 37-42页

作者： Maissa Ben thayer Fatma Khanchel Imen Helal Dorra Chiboub Hedhli Raoueh Ehsen Ben Brahim Raja Jouini Aschraf Chadli-Debbiche Faculty of Medicine of Tunis Tunis El Manar UniversityTunisTunisia Depatment of Pathology Habib Thameur's HospitalTunisTunisia Department of Otorhinolaryngology-Head and Neck surgery Habib Thameur's HospitalTunisTunisia

Background:Thyroid carcinoma(TC)accounts for almost 0.5%–1%of total *** incidence is increasing rapidly *** studies have drawn up the epidemiological profile of TC and its clinical and pathological ***,to date,no similar studies have been conducted in ***:To establish an epidemiological profile of TC in a Tunisian health care institute and to analyze its clinical and histopathological characteristics in our *** and Methods:We present a retrospective study reviewing the cases of TC diagnosed in our institution in a 4-year ***:We collected a sample of 192 cases of *** consisted of 31 males and 161 females(83.8%)with a sex-ratio M/F of *** mean age was 46.4 *** thyroid carcinoma was the most frequent histological *** multifocality rate was 33.8%.The mean size of TC was 2.2±1.9 cm.60.9%of TC were staged pT1 and 20.3%had nodal *** thyroid microcarcinomas were noted in 37.5%of ***:Our results were consistent with those of the literature.A high proportion of pT1 and pN0 tumors were noted in our series,suggesting that TC's diagnosis and management was performed at an early stage of the disease in our *** addition,our study enabled us to notice the impact of the Coronavirus disease 19 crisis on the management of TC in our *** studies are needed to establish the epidemiological profile of TC in Tunisia and to assess its clinical and pathological features.

关键词： coronavirus disease 19 epidemiology papillary thyroid carcinoma papillary thyroid microcarcinoma pathology thyroid carcinoma

Evaluation of stress-control layout at the Subtropolis Mine,Petersburg,Ohio

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International Journal of Mining Science and Technology 2020年第1期30卷 77-83页

作者： Anthony Iannacchione Tim Miller Gabriel Esterhuizen Brent Slaker Michael Murphy Natalie Cope Scott thayer Department of Civil and Environmental Engineering University of PittsburghPittsburghPA 15216USA East Fairfield Coal Company North LimaOH 44452USA National Institute for Occupational Safety and Health(NIOSH) Pittsburgh Mining Research DivisionPittsburghPA 15236USA Mine Vision Systems Inc. PittsburghPA 1520USA

The Subtropolis room-and-pillar mine extracts the Vanport Limestone(Allegheny Formation,Pennsylvanian System)near Petersburg,*** instability problems associated with excessive concentrations of lateral stress caused the mine operator to implement a change in layout *** mining method has been identified as a stress control layout and has been used by other underground stone mines in the past with varying degrees of *** experience has shown that entry headings advance in the direction of the principal lateral stress,producing lower stress concentrations with better mining *** is important to minimize stress concentrations along the mining front,so an arrowshaped advance is *** technique advances more developments(headings)in a"good"direction and reduces developments(crosscuts)in the"bad direction."As is expected,the stress control layout enhances the potential for shear failures in *** is,therefore,important to focus crosscut engineering interventions that either:(a)lower stress concentrations(for example,an arched roof)or(b)enhance strength of the strata containing the shears(for example,rock reinforcement).This study focuses on observing strata conditions on a regular basis and monitoring the response of these strata to changing geologic and mining conditions through 3D Dynamic LiDAR scans.

关键词： Horizontal stress Stress-control layouts Underground stone mines

Superior Performance of Teaching and Transplant Hospitals in the Management of Hepatic Encephalopathy from 2007 to 2014

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Journal of Clinical and Translational Hepatology 2018年第4期6卷 362-371页

作者： Daniel Bodek Pavan Patel Sushil Ahlawat Evan Orosz thayer Nasereddin Nikolaos Pyrsopoulos Rutgers New Jersey Medical School University HospitalNewarkNJUSA

Background and Aims:Hepatic encephalopathy is a liver disease complication with significant mortality and *** aim of this study was to evaluate the relative performance of facilities based on their teaching status and transplant capability by correlating their connections to mortality,cost,and length of stay from 2007 to ***:The Nationwide Inpatient Sample database was utilized to collect information on(USA)American patients admitted with a primary diagnosis of hepatic encephalopathy from *** were placed into one of four categories using their teaching and transplant *** regression analysis,mortality,length of stay and cost adjusted rate ratios were ***:The study revealed that teaching transplant centers had a mortality risk ratio of 0.783(95%confidence interval(CI):0.750-0.819,p<0.001).Blacks had the highest mortality risk ratio,of 1.273(95%CI:1.217-1.331,p<0.001).Furthermore,teaching transplant hospitals had a cost rate ratio of 1.226(95%CI:1.214-1.238,p<0.001)and a length of stay rate ratio of 1.104(95%CI:1.093-1.115,p<0.001).Conclusions:It appears that admission to transplant facilities for hepatic encephalopathy is associated with reduced mortality but increased costs and longer stay independent of ***,factors impacting black mortality should also be examined more closely.

关键词： Disparities Mortality Cost Length of stay Hepatic encephalopathy

Visual Basic 6 unleashed Rob thayer, ... [et al.]. Professional reference ed.

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Visual Basic 6 unleashed Rob Thayer, ... [et al.].

Linking evolutionary mode to palaeoclimate change reveals rapid radiations of staphylinoid beetles in low-energy conditions

1999年

作者： Rob thayer ... [et al.].

来源：畅想之星图书光盘版（南... 评论

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Current Zoology 2020年第4期66卷 435-444页

作者： Liang LU Chen-Yang CAI Xi ZHANG Alfred FNewton Margaret K.thayer Hong-Zhang ZHou Key Laboratory of Zoological Systematics and Evolution Institute of ZoologyChinese Academy of Sciences1 Beichen West RdChaoyang DistrictBeijing 100101China College of Life Science Hebei Normal UniversityNo.20 Road East 2nd Ring SouthYuhua DistrictShijiazhuangHebei 050024China University of Chinese Academy of Sciences 19AYuquan RdShijingshan DistrictBeijing 100049China Key Laboratory of Economic Stratigraphy and Palaeogeography Nanjing Institute of Geology and Palaeontologyand Centre for Excellence in Life and Paleoenvironment Chinese Academy of SciencesNanjing 210008China School of Earth Sciences University of BristolLife Sciences BuildingTyndall AvenueBristol BS81TQUK department of Parasitology Medical CollegeZhengzhou UniversityZhengzhou 450052China Integrative Research Center Field Museum of Natural HistoryChicagoIL 60605USA Committee on Evolutionary Biology University of ChicagoChicagoIL 60637USA

Staphylinoidea(Insecta:Coleoptera)is one of the most species-rich groups in animals,but its huge diversity can hardly be explained by the popular hypothesis(co-radiation with angiosperms)that applies to phytophagous *** estimated the evolutionary mode of staphylinoid beetles and investigated the relationship between the evolutionary mode and palaeoclimate change,and thus the factors underlying the current biodiversity pattern of staphylinoid *** results demonstrate that staphylinoid beetles originated at around the Triassic-Jurassic bound and the current higher level clades underwent rapid evolution(indicated by increased diversification rate and decreased body size disparity)in the Jurassic and in the Cenozoic,both with low-energy climate,and they evolved much slower during the Cretaceous with high-energy *** factors,especially low 02 and high C02,promoted the diversification rate and among-clade body size disparification in the *** the Cenozoic,however,climate factors had negative associations with diversification rate but little with body size *** present study does not support the explosion of staphylinoid beetles as a direct outcome of the Cretaceous Terrestrial Revolution(KTR).We suppose that occupying and diversifying in refuge niches associated with litter may elucidate rapid radiations of staphylinoid beetles in low-energy conditions.

关键词： evolutionary diversification low-energy conditions palaeoclimate change rapid radiation Staphylinoidea

ECMO in major burn patients: feasibility and considerations when multiple modes of mechanical ventilation fail

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Burns & Trauma 2017年第2期5卷 134-139页

作者： Jason D. Kennedy Wesley thayer Reuben Beuno Kelly Kohorst Avinash B. Kumar Department of Anesthesiology and Critical Care Vanderbilt University Medical Center 121121st Avenue S Suite 526 Nashville TN 37212 USA Department of Plastic Surgery Vanderbilt University Nashville TN USA

Background: We report two cases of acute respiratory distress syndrome in burn patients who were successfully managed with good outcomes with extra corporeal membrane oxygenation (ECMO) after failing multiple conventional modes of ventilation, and review the relevant *** presentation: The two patients were a 39-year-old male and 53-year-old male with modified Baux Scores of 79 and 78, respectively, with no known inhalation injury. After the initial modified Parkland-based fluid resuscitation and partial escharotomy, both patients developed worsening hypoxemia and acute respiratory distress *** hypoxemia continued to worsen on multiple modes of ventilation including volume control, pressure regulated volume control, pressure control, airway pressure release ventilation and volumetric diffusive *** both cases, the PaO2 ≤ 50 mm Hg on a FiO2100% during the trial of mechanical ventilation. The deterioration was rapid (<12 h since onset of worsening oxygenation) in both cases.A decision was made to trial the patients on ECMO. Veno-Venous ECMO (V-V ECMO) was successfully initiated following cannulation-under transesophgeal echo guidance—with the dual lumen Avalon? (Maquet, NJ, USA) cannula. ECMO support was maintained for 4 and 24 days, respectively. Both patients were successfully weaned off ECMO and were discharged to rehabilitation following their complex hospital ***: Early ECMO for isolated respiratory failure in the setting on maintained hemodynamics resulted in a positive outcome in our two burn patients suffered from acute respiratory distress syndrome.

关键词： ARDS Burns Extra corporeal membrane oxygenation Rescue ventilation Conventional ventilation failure Veno-venous ECMO

Effect of absorbed dose and storage length on electron paramagnetic resonance (EPR) signal strength in irradiated alfalfa seeds

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Nuclear Science and Techniques 2006年第2期17卷 83-85页

作者： LI Nai-Nin D. W. thayer R. GATES D. SCHWARTZ R. RICHARDSON Institute of Atomic Energy Application Jiangsu Academy of Agricultural Sciences （JAAS） Nanjing 210014 China Food Safety Research United States Department of Agriculture Agricultural Research Service Eastern Regional Research Center 600 East Mermaid lane Wyndmoor Pennsylvania 19038 USA

A kind of alfalfa seeds was irradiated by 1, 2, 3, 4 and 5 kGy at a dose rate of 6.288 kGy·h-1 in a self-shielded irradiator of 137Cs gamma rays. The EPR spectra, which were measured subsequently between 0.3401 and 0.3501 T, showed that there was a direct proportional relationship between the EPR signal strength of free radi- cals produced by gamma irradiation in the alfalfa seeds and absorbed dose. The first derivative EPR spectra of the al- falfa seeds were very clear and easy to identify. However, the EPR signal strength of the peak-to-peak amplitude de- creased rapidly and most of them decayed beyond 50% within 3 days after the seeds were irradiated. It tended to sta- bilize after half a month since the seeds were irradiated. The differences of the EPR signal strength between the irra- diated and unirradiated alfalfa seeds still remained. All seeds were stored at ambient temperature for more than 3 months. Therefore, using EPR spectrometry technique to measure free radicals in alfalfa seeds as a means to deter- mine whether the seeds have been irradiated or not is feasible, relatively fast and simple.

关键词：紫花苜蓿种子 EPR光谱自由基 Gamma辐射

A novel technique using hydrophilic polymers to promote axonal fusion

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Neural Regeneration Research 2016年第4期11卷 525-528页

作者： Ravinder Bamba D.Colton Riley Nathaniel D.Kelm Mark D.Does Richard D.Dortch Wesley P.thayer Department of Plastic Surgery Vanderbilt University Medical Center Nashville TN USA Department of Surgery Georgetown University Washington DC USA Georgetown University School of Medicine Washington DC USA Vanderbilt University Institute of Imaging Science Nashville TN USA Department of Radiology and Radiological Sciences Vanderbilt University Nashville TN USA

The management of traumatic peripheral nerve injury remains a considerable concern for *** minimal innovations in surgical technique and a limited number of specialists trained to treat peripheral nerve injury,outcomes of surgical intervention have been *** inability to manipulate the pathophysiology of nerve injury（i.e.,Wallerian degeneration） has left scientists and clinicians depending on the slow and lengthy process of axonal regeneration（-1 mm/day）.When axons are severed,the endings undergo calcium-mediated plasmalemmal sealing,which limits the ability of the axon to be primarily *** glycol（PEG） in combination with a bioengineered process overcomes the inability to fuse *** mechanism for PEG axonal fusion is not clearly understood,but multiple studies have shown that a providing a calcium-free environment is essential to the process known as PEG *** proposed mechanism is PEG-induced lipid bilayer fusion by removing the hydration barrier surrounding the axolemma and reducing the activation energy required for membrane fusion to *** review highlights PEG fusion,its past and current studies,and future directions in PEG fusion.

关键词： peripheral nerve injury polyethylene glycol axonal fusion nerve transection traumatic neuropathy

Polyethylene glycol restores axonal conduction after corpus callosum transection

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Neural Regeneration Research 2017年第5期12卷 757-760页

作者： Ravinder Bamba D.Colton Riley Richard B.Boyer Alonda C.Pollins R.Bruce Shack Wesley P.thayer Department of Plastic Surgery Vanderbilt University Medical Center Nashville TN USA Department of Surgery Georgetown University Washington DC USA Georgetown University School of Medicine Washington DC USA

Polyethylene glycol（PEG） has been shown to restore axonal continuity after peripheral nerve transection in animal models. We hypothesized that PEG can also restore axonal continuity in the central nervous system. In this current experiment, coronal sectioning of the brains of Sprague-Dawley rats was performed after animal sacrifice. 3Brain high-resolution microelectrode arrays（MEA） were used to measure mean firing rate（MFR） and peak amplitude across the corpus callosum of the ex-vivo brain slices. The corpus callosum was subsequently transected and repeated measurements were performed. The cut ends of the corpus callosum were still apposite at this time. A PEG solution was applied to the injury site and repeated measurements were performed. MEA measurements showed that PEG was capable of restoring electrophysiology signaling after transection of central nerves. Before injury, the average MFRs at the ipsilateral, midline, and contralateral corpus callosum were 0.76, 0.66, and 0.65 spikes/second, respectively, and the average peak amplitudes were 69.79, 58.68, and 49.60 μV, respectively. After injury, the average MFRs were 0.71, 0.14, and 0.25 spikes/second, respectively and peak amplitudes were 52.11, 8.98, and 16.09 μV, respectively. After application of PEG, there were spikes in MFR and peak amplitude at the injury site and contralaterally. The average MFRs were 0.75, 0.55, and 0.47 spikes/second at the ipsilateral, midline, and contralateral corpus callosum, respectively and peak amplitudes were 59.44, 45.33, 40.02 μV, respectively. There were statistically differences in the average MFRs and peak amplitudes between the midline and non-midline corpus callosum groups（P 〈 0.01, P 〈 0.05）. These findings suggest that PEG restores axonal conduction between severed central nerves, potentially representing axonal fusion.

关键词： nerve regeneration polyethylene glycol nerve repair axonal fusion central nerve injury axonal conduction corpus callosum neural regeneration