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Comparison of incidence of acute kidney injury after robot-assisted radical prostatectomy with that after open retropubic and extraperitoneal laparoscopic radical prostatectomies in patients with prostate cancer

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Current Urology 2024年第2期18卷 139-143页

作者： Shunsuke Sato Toshiaki Tanaka Takeshi Maehana kohei Hashimoto ko kobayashi Naoya Masumori Department of Urology Sapporo Medical UniversitySapporoJapan

Background:We retrospectively evaluated the postoperative renal function in patients who had undergone radical prostatectomy to compare the incidences of postoperative acute kidney injury(AKI)among the patients who had undergone robot-assisted radical prostatectomy(RARP),retropubic radical prostatectomy(RRP),and extraperitoneal laparoscopic radical prostatectomy(exLRP).Materials and methods:Patients with prostate cancer who had undergone radical prostatectomy at our institution between 2008 and 2014 were ***-assisted radical prostatectomy was performed using an intraperitoneal approach in a 25-degree Trendelenburg position,whereas other procedures were performed with the patient in the supine *** evaluated the serum creatinine levels and estimated glomerular filtration rates immediately after surgery and on postoperative day *** evaluated the incidence of AKI after prostatectomy using the Acute Kidney Injury Network criteria of the Kidney Disease:Improving Global Outcomes ***:A total of 150 consecutive patients were included,with each of the 3 groups(RARP,RRP,and exLRP)comprising 50 *** AKI was observed in 15(30.0%),1(2.0%),and 3(6.0%)patients in the RARP,RRP,and exLRP groups,*** 1 AKI was observed in all the patients except *** incidence of AKI in RARP group was significantly higher than that in the other groups(p<0.001).In the RARP group,the serum creatinine level was significantly elevated immediately after the surgery;however,it returned to baseline on postoperative day *** procedures were the only independent factor associated with AKI ***:This study suggest that compared with RRP and exLRP,RARP is associated with a higher incidence of postoperative AKI,although most patients recover ***-abdominal pneumoperitoneum may contribute to AKI onset.

关键词： Acute kidney injury Renal function Prostatectomy

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Which characteristics are associated with changes in medication status for lower urinary tract symptoms among patients with prostate cancer receiving external beam radiotherapy?

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Current Urology 2024年第2期18卷 122-127页

作者： Yuki Kyoda kohei Hashimoto Atsushi Takahashi TakeshiMaehana Kimihito Tachikawa Takashi Muranaka Shuichi Kato Tomoyo Kurisug Fumimasa Fukuta Takahiro Kirisawa Manabu Okada ko kobayashi Toshiaki Tanaka Shiro Hinotsu Naoya Masumoria Department of Urology SapporoMedical University School of MedicineSapporoJapan Department of Urology Hakodate Goryoukaku HospitalHakodateJapan Department of Urology Muroran City General HospitalMuroranJapan Department of Urology NTT-East Sapporo HospitalSapporoJapan Department of Urology Sunagawa City Medical CenterSunagawaJapan Department of Urology Oji General HospitalTomakomaiJapan Department of Urology Steel Memorial Muroran HospitalMuroranJapan Department of Urology Obihiro Kyokai HospitalObihiroJapan Department of Medical Statistics Sapporo Medical University School of MedicineSapporoJapan

Background:We clarified the predictive factors for changes in the status ofmedications for lower urinary tract symptoms(LUTS)2 years after local radiotherapy for nonmetastatic prostate *** and methods:We retrospectively included patients who underwent local external radiotherapy for nonmetastatic prostate cancer in 8 institutions between April 2001 and March *** were divided into themedication and no-medication group based on the use of drugs for LUTS before *** defined improvement of LUTS as when the patient did not require medication for LUTS at 24 months after radiotherapy in the medication group and as deterioration whenmedication was required in the no-medication *** regression analysis was used to evaluate predictive factors for changes in medication ***:Altogether,505 patients were divided into a no-medication group(n=352)and a medication group(n=153).The number of patients with deterioration and improvement in LUTS was 49(14%)and 36(23%),*** the multivariate analysis,the predictive variables for deterioration were the International Prostate SymptomScore(≥8;odds ratio[OR],2.21;p=0.014)and the biopsy Gleason score(≤3+4=7;OR,2.430;p=0.008)in the no-medication group,whereas those for improvement were age(<75 years old;OR,5.81;p=0.002),the quality of life score(<3;OR,3.15;p=0.028),and a positive biopsy core rate(≥50%;OR,2.530;p=0.027)in the medication ***:These predictive factors for changes in the status ofmedications for LUTS at 2 years after external radiotherapymay help determine the definitive therapy for nonmetastatic prostate cancer.

关键词： Prostate cancer Radiotherapy Lower urinary tract symptoms Medications

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Difference in symptom manifestation between postmenopausal and premenopausal women in acute uncomplicated cystitis:A multi-institutional pilot study

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Current Urology 2023年第3期17卷 174-178页

作者： Atsushi Wanifuchi Yuki Kyoda Takuto Ogasawara ko kobayashi Naoki Ito Tetsuya Shindo Atsushi Takahashi Yasuharu Kunishima Naoya Masumori Department of Urology Sapporo Medical University School of MedicineSapporo060-8543Japan Department of Urology NTT East Sapporo HospitalSapporoJapan Department of Urology Hakodate Goryoukaku HospitalHakodateJapan Department of Urology Sunagawa City Medical CenterSunagawaJapan

Objectives:We aimed to prospectively compare lower urinary tract symptoms in premenopausal and postmenopausal women with acute uncomplicated cystitis before and after antibiotic *** and methods:This study included adult women with acute uncomplicated cystitis who visited 4 institutions between 2019 and *** registration,we administered oral antibiotics and prospectively documented the changes in lower urinary tract symptoms from the first visit to a follow-up visit at 1 week using the Core Lower Urinary Tract Symptoms Score(CLSS)***:After treatment,pyuria disappeared in 60 of the 66 patients(14 premenopausal and 46 postmenopausal).The CLSS total score(range)changed from 13(3-29)to 4(0-18)with a significant improvement in all CLSS *** baseline,nocturia,urgency,and urgency incontinence were more prominent in postmenopausal women than in premenopausal *** contrast,baseline urethral pain and quality of life index were more severe in premenopausal women than in postmenopausal *** treatment,the CLSS total score was still higher in postmenopausal women,as reflected by the relatively higher scores for nocturia and urgency,irrespective of the comparable scores for urethral pain and the quality of life index in the 2 ***:Our results suggest that if storage symptoms persist,they should be carefully interpreted according to menopausal status.

关键词： Acute uncomplicated cystitis Core Lower Urinary Tract Symptoms Score Lower urinary tract symptoms Postmenopausal women

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Fundamental Study on Response Properties of Structures Constructed on Lunar Regolith

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Open Journal of Earthquake Research 2024年第1期13卷 27-40页

作者： Yuji Miyamoto Takaharu Nakano Toshio kobayashi Department of Architecture and Civil Engineering Fukui University of Technology Fukui Japan Graduate School of Engineering Osaka University Osaka Japan SANSEI Inc. Tokyo Japan

The Artemis Program, for constructing the lunar base, is in progress. How to design and construct architectural and civil engineering structures in the lunar environment has become an important issue. The lunar surface is covered with soft sand, called regolith, and it is required to protect lunar bases and structures, as well as internal precision equipment, against vibrational disturbances such as moonquakes and meteorite collisions. Therefore, in this study, the static and cyclic triaxial compression tests of the regolith simulant were conducted. The reference strain and equivalent damping factor of the regolith simulant were smaller compared to sandy soil on Earth. In addition, a shaking table test using model specimens was conducted on the response properties of regolith ground alone and structures set on regolith ground. The buried foundation and pile foundation notably suppressed the horizontal response attributed to the rocking component compared to a direct foundation.

关键词： Lunar Development Regolith Soil-Structure Interaction Triaxial Compression Test Shaking Table Test

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TiO₂-PES Fibrous Composite Material for Ammonia Removal Using UV-A Photocatalyst

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Journal of Materials Science and Chemical Engineering 2024年第1期12卷 1-19页

作者： Anh Phuong Le Thi Masaru Ohshiro Takaomi kobayashi Department of Science and Technology Innovation Nagaoka University of Technology Nagaoka Japan Kasai Corporation Niigata Japan

This study focused on the development and characterization of TiO2-PES composite fibers with varying TiO2 loading amounts using a phase inversion process. The resulting composite fibers exhibited a sponge-like structure with embedded TiO2 nanoparticles within a polymer matrix. Their photocatalytic performance for ammonia removal from aqueous solutions under UV-A light exposure was thoroughly investigated. The findings revealed that PeTi8 composite fibers displayed superior adsorption capacity compared to other samples. Moreover, the study explored the impact of pH, light intensity, and catalyst dosage on the photocatalytic degradation of ammonia. Adsorption equilibrium isotherms closely followed the Langmuir model, with the results indicating a correlation between qm values of 2.49 mg/g and the porous structure of the adsorbents. The research underscored the efficacy of TiO2 composite fibers in the photocatalytic removal of aqueous under UV-A light. Notably, increasing the distance between the photocatalyst and the light source resulted in de-creased hydroxyl radical concentration, influencing photocatalytic efficiency. These findings contribute to our understanding of TiO2 composite fibers as promising photocatalysts for ammonia removal in water treatment applications.

关键词： Ammonia Removal Photocatalyst TiO2-PES Composite Fiber Fibrous Material

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Unroofing Technique for Anomalous Origin of the Left Coronary Artery from the Right Sinus of Valsalva: Report of a Case

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World Journal of Cardiovascular Surgery 2024年第6期14卷 69-77页

作者： Keisuke Morimoto Futoshi kobayashi Hiromu Horie Yuki Sakaguchi Einosuke Mizuta Department of Cardiovascular Surgery Sanin Rosai Hospital Yonago Japan Department ofCardiology Sanin Rosai Hospital Yonago Japan

Anomalous origin of the left coronary artery (AOLCA) from the right sinus of Valsalva constitutes a rare congenital coronary artery anomaly. Patients with an anomalous left main coronary artery face a significantly higher risk of sudden cardiac death compared to those with an anomalous right coronary artery. The anomalous coronary artery traversing between the ascending aorta and the pulmonary artery markedly heightens the risk of myocardial ischemia, arrhythmia, and sudden death. Symptomatic patients often exhibit a longer intramural course of the coronary artery, which may necessitate earlier intervention or influence the choice of surgical repair method. Surgical intervention is advocated for patients with this anomaly, even in the absence of symptoms. For anomalous aortic origin of a coronary artery from the opposite sinus of Valsalva with an intramural course, coronary unroofing is the preferred revascularization procedure. This report presents a case of AOLCA originating from the right sinus of Valsalva, treated surgically using the unroofing technique for the aortic intramural segment of the anomalous coronary artery traversing between the great vessels. The unroofing technique is recommended for treating AOLCA with an extensive intramural course that does not involve the commissure.

关键词： Unroofing Technique Anomaly of Coronary Artery Anomalous Origin of Left Coronary Artery

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Conversion surgery after gemcitabine and cisplatin plus durvalumab for advanced intrahepatic cholangiocarcinoma:A case report

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World Journal of Clinical Cases 2024年第34期12卷 6721-6727页

作者： Yu Igata Masashi Kudo Motohiro kojima Shota Kami Keishiro Aoki Tomoyuki Satake Tatsushi kobayashi Motokazu Sugimoto Shin kobayashi Masaru konishi Naoto Gotohda Department of Hepatobiliary and Pancreatic Surgery National Cancer Center Hospital EastKashiwa 277-8577Japan Exploratory Oncology Research and Clinical Trial Center National Cancer CenterKashiwa 277-8577Japan Department of Hepatobiliary and Pancreatic Oncology National Cancer Center Hospital EastKashiwa 277-8577Japan Department of Diagnostic Radiology National Cancer Center Hospital EastChiba 277-8577Japan

BACKGROUND The combination of immune checkpoint inhibitors and chemotherapy has shown promising results for the treatment of advanced biliary tract cancer(BTC).Based on the results of the TOPAZ-1 trial,a gemcitabine and cisplatin plus durvalumab(GCD)regimen was recently approved as first-line therapy for patients with advanced ***,post-GCD conversion surgery has not been previously ***,we describe a case of advanced intrahepatic cholangiocarcinoma(ICC)successfully treated with radical surgery after *** SUMMARY A 65-year-old female diagnosed with advanced ICC with periductal infiltration into the hepatic hilum underwent eight cycles of GCD,followed by durvalumab maintenance treatment,with mild adverse *** response was ***,a conversion surgery with extended left hepatectomy and bile duct resection was *** resection margins were negative,and the pathological diagnosis was compatible with small duct type *** patient remained disease-free for 8 months without adjuvant *** We describe the case of a patient who received successful conversion surgery after GCD treatment for advanced ICC.

关键词： Conversion surgery Intrahepatic cholangiocarcinoma Small duct type Immunotherapy Case report

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Static Stretching Combined with Conscious Slower Breathing May Increase Parasympathetic Activity and Reduce Stress in Adult Women

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Health 2024年第3期16卷 242-256页

作者： Mami Sakurai Yasushi Ikarashi Masahiro Tabuchi Ailing Hu Takuji Yamaguchi Hiroyuki kobayashi Department of Hospital Administration Juntendo University Graduate School of Medicine Tokyo Japan Department of Beauty & Wellness Professional University of Beauty & Wellness Yokohama Japan Department of Personalized Kampo Medicine Juntendo University Graduate School of Medicine Tokyo Japan

Background: Women are thought to be more susceptible to stress than men in a stressful society, and reducing stress is crucial for women to maintain their health. Static stretching (SST) is applied in various fields to not only increase muscle flexibility but also reduce stress. Additionally, conscious slower breathing (CSB) predominates parasympathetic activity, causing a relaxing effect. These results indicate that combining SST and CSB may be more useful in reducing stress. However, to the best of our knowledge, the effect of this combination remains unclear. Objective: This study aimed to elucidate the effects of the combination of SST and CSB on autonomic activity and stress in adult women. Methods: Eleven healthy Japanese adult female participants performed SST with nonconscious natural breathing for 20 min. The same participants performed SST in combination with CSB (2 s inspiratory and 4 s expiratory) for 20 min on another day. Salivary cortisol and chromogranin A levels were measured before and after stretching as stress markers of the hypothalamic-pituitary-adrenal axis and sympathetic nervous system. The coefficient of variation of the R-R interval (CVR-R) and high-frequency component (HF), which reflect parasympathetic nerve activity, and heart rate and low-frequency component (LF)/HF ratio, which reflect sympathetic nerve activity, were measured before, during, and after stretching. Results: SST decreased cortisol levels but with no significant changes in chromogranin A, heart rate, CVR-R, HF, or LF/HF ratio. The combination of SST and CSB increased CVR-R and HF levels in addition to decreasing cortisol levels but with no significant changes in chromogranin A, heart rate, or LF/HF levels. Conclusion: These results indicate that the combination of SST and CSB may increase parasympathetic activity and reduce stress. However, future randomized controlled trials with larger sample sizes should support this conclusion.

关键词： Static Stretching Conscious Slower Breathing Autonomic Activity Heart Rate Variability Stress

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Adult-Type Granulosa Cell Tumor with Similar Clinical Findings Seen during Ovarian Cystectomy Performed at the Same Time as Laparoscopic Ovarian Drilling for Polycystic Ovarian Syndrome: An Extremely Rare Case

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Open Journal of Obstetrics and Gynecology 2024年第8期14卷 1197-1206页

作者： Remi Nakajima Risa kobayashi Marie Kawai Eriko Sakamoto Miho Matsuda Rieko Kanda Makoto Kawamura Department of Obstetrics and Gynecology Kohseichuo General Hospital. Tokyo Japan

Polycystic ovary syndrome (PCOS) is a major cause of anovulatory infertility. Laparoscopic ovarian drilling (LOD) is a treatment for PCOS that allows the laparoscopic identification of other intra-abdominal lesions and the provision of diagnostic treatment. This study reports a case of PCOS with an ovarian mass in which LOD was aggressively used and a granulosa cell tumor (GCT) was found. A 34-year-old woman with secondary amenorrhea and irregular menstrual cycles presented to the emergency department with abdominal pain of unknown etiology. Imaging studies revealed a 6-cm left ovarian mass with an internal appearance suggestive of a hemorrhage. The patient’s secondary amenorrhea was subsequently diagnosed as PCOS, and LOD was performed to preserve her fertility. Simultaneously, a cystectomy was performed to evaluate the tumor in the left ovary;the diagnosis was adult-type GCT. Although concomitant GCT and PCOS are extremely rare, the two conditions have similar clinical manifestations. In women of reproductive age, the impact of surgery on future fertility should be considered, and the initial surgical technique should be chosen carefully.

关键词： Polycystic Ovary Syndrome Laparoscopic Ovarian Drilling Granulosa Cell Tumor

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在中国简牍研究中应用日本木简研究成果的可能性——以马场基《日本古代木简论》为切入点

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敦煌学辑刊 2024年第1期1卷 25-38页

作者：小林文治南开大学历史学院天津300350

近年来,简牍研究的理论内容高速发展,并集中于“简牍学”的形成。在这样的大背景下,中国的简牍研究者开始着眼于国外的简牍研究成果也实属必然。日本木简的研究成果总量十分庞大,并且研究分类十分细致。马场基所著的《日本古代木简论》... 详细信息

近年来,简牍研究的理论内容高速发展,并集中于“简牍学”的形成。在这样的大背景下,中国的简牍研究者开始着眼于国外的简牍研究成果也实属必然。日本木简的研究成果总量十分庞大,并且研究分类十分细致。马场基所著的《日本古代木简论》着重展现、推进了东亚研究视野下的木简研究,充分体现了现阶段日本木简研究最前沿的成果。本文认为,马场氏的研究方式或许蕴含着能给中国的简牍研究带来全新的视角和研究方式的可能性。本文通过马场氏著作的相关讨论,对如何将日本木简研究中的方法应用至中国简牍研究进行探讨。

关键词：日本木简中国简牍简牍学

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