Difference in symptom manifestation between postmenopausal and premenopausal women in acute uncomplicated cystitis:A multi-institutional pilot study

作     者：Atsushi Wanifuchi Yuki Kyoda Takuto Ogasawara Ko Kobayashi Naoki Ito Tetsuya Shindo Atsushi Takahashi Yasuharu Kunishima Naoya Masumori 

作者机构：Department of UrologySapporo Medical University School of MedicineSapporo060-8543Japan Department of UrologyNTT East Sapporo HospitalSapporoJapan Department of UrologyHakodate Goryoukaku HospitalHakodateJapan Department of UrologySunagawa City Medical CenterSunagawaJapan 

出 版 物：《Current Urology》 (当代泌尿学（英文）)

年 卷 期：2023年第17卷第3期

页      面：174-178页

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：Acute uncomplicated cystitis Core Lower Urinary Tract Symptoms Score Lower urinary tract symptoms Postmenopausal women 

摘      要：Objectives:We aimed to prospectively compare lower urinary tract symptoms in premenopausal and postmenopausal women with acute uncomplicated cystitis before and after antibiotic *** and methods:This study included adult women with acute uncomplicated cystitis who visited 4 institutions between 2019 and *** registration,we administered oral antibiotics and prospectively documented the changes in lower urinary tract symptoms from the first visit to a follow-up visit at 1 week using the Core Lower Urinary Tract Symptoms Score(CLSS)***:After treatment,pyuria disappeared in 60 of the 66 patients(14 premenopausal and 46 postmenopausal).The CLSS total score(range)changed from 13(3-29)to 4(0-18)with a significant improvement in all CLSS *** baseline,nocturia,urgency,and urgency incontinence were more prominent in postmenopausal women than in premenopausal *** contrast,baseline urethral pain and quality of life index were more severe in premenopausal women than in postmenopausal *** treatment,the CLSS total score was still higher in postmenopausal women,as reflected by the relatively higher scores for nocturia and urgency,irrespective of the comparable scores for urethral pain and the quality of life index in the 2 ***:Our results suggest that if storage symptoms persist,they should be carefully interpreted according to menopausal status.